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The map label for this gene is trpG [H]

Identifier: 93006748

GI number: 93006748

Start: 2375094

End: 2375741

Strand: Direct

Name: trpG [H]

Synonym: Pcryo_1924

Alternate gene names: 93006748

Gene position: 2375094-2375741 (Clockwise)

Preceding gene: 93006747

Following gene: 93006749

Centisome position: 77.62

GC content: 44.75

Gene sequence:

>648_bases
ATGAATGTTTTAATTATCGATAATTACGACTCATTTACTTTCAACCTTTACCAGTATATCGGTGAGATCTTGCAGACGAT
GGACAGTGATAAACAAGCAAATGTCATCGTCAAGCGTAATAATGAAATCACCTTAGCAGACGTACAAGCGATGAGTCTTG
ACCGTATTATTATCTCACCCGGTCCTGGGTCACCTGATGATCCTGCCTATTTTGGCATTTGTGCCGAAGTGATTGAAGTG
ATGGGCAAAACGACGCCACTATTAGGCGTTTGCTTAGGCATGCAGGGCATTGCTCATGTATTTGGCGGTGATGTGATACG
CGCCAGTGTGCCGATGCATGGCAAGGTTTCAGCCATTCGTCATGATGGTGCGGGCATTTATAATGATTTGCCGCAGCATT
TAGAAATCATGCGCTATCATTCATTGATGGTACAAGCAGACACGCTACCGGATTGTTTGACTGTCACAGCAGTCGTCGCC
AATGATGAACATAATGATTTAGAGTTGACTGAATCGGCGCTGGCTGGTGATGAGATAATGGGTGTGCAGCACAAAGACTA
TCCGATTCAAGGCGTGCAGTTTCACCCAGAGTCATTTGCGACCGAAGGTGCCAAGCGTTTATTGACGAATTTTTTACTTC
AGGTGTAA

Upstream 100 bases:

>100_bases
AATATCTAGAAATCCAGCGTAAGCTTTCTGCTATGAAAGTGGTACTAGACAGCTTTATGAACCCATAACCACATATAATT
TATCAAAGAGTTGGCCACCC

Downstream 100 bases:

>100_bases
ATCACGATGCTTAAGATGGTTTGGAGGATATGACGCTAAAGAGTAATAAGCTGAAGTGAAGCCTGCATCTAACTCAAATA
AATTGCATTTTATGTCTAAC

Product: glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MNVLIIDNYDSFTFNLYQYIGEILQTMDSDKQANVIVKRNNEITLADVQAMSLDRIIISPGPGSPDDPAYFGICAEVIEV
MGKTTPLLGVCLGMQGIAHVFGGDVIRASVPMHGKVSAIRHDGAGIYNDLPQHLEIMRYHSLMVQADTLPDCLTVTAVVA
NDEHNDLELTESALAGDEIMGVQHKDYPIQGVQFHPESFATEGAKRLLTNFLLQV

Sequences:

>Translated_215_residues
MNVLIIDNYDSFTFNLYQYIGEILQTMDSDKQANVIVKRNNEITLADVQAMSLDRIIISPGPGSPDDPAYFGICAEVIEV
MGKTTPLLGVCLGMQGIAHVFGGDVIRASVPMHGKVSAIRHDGAGIYNDLPQHLEIMRYHSLMVQADTLPDCLTVTAVVA
NDEHNDLELTESALAGDEIMGVQHKDYPIQGVQFHPESFATEGAKRLLTNFLLQV
>Mature_215_residues
MNVLIIDNYDSFTFNLYQYIGEILQTMDSDKQANVIVKRNNEITLADVQAMSLDRIIISPGPGSPDDPAYFGICAEVIEV
MGKTTPLLGVCLGMQGIAHVFGGDVIRASVPMHGKVSAIRHDGAGIYNDLPQHLEIMRYHSLMVQADTLPDCLTVTAVVA
NDEHNDLELTESALAGDEIMGVQHKDYPIQGVQFHPESFATEGAKRLLTNFLLQV

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=210, Percent_Identity=46.1904761904762, Blast_Score=188, Evalue=2e-49,
Organism=Escherichia coli, GI1787517, Length=214, Percent_Identity=32.2429906542056, Blast_Score=105, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6322638, Length=211, Percent_Identity=40.7582938388626, Blast_Score=162, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6324361, Length=228, Percent_Identity=32.8947368421053, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 23557; Mature: 23557

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLIIDNYDSFTFNLYQYIGEILQTMDSDKQANVIVKRNNEITLADVQAMSLDRIIISP
CEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEEEEHEEEECEEEECC
GPGSPDDPAYFGICAEVIEVMGKTTPLLGVCLGMQGIAHVFGGDVIRASVPMHGKVSAIR
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEE
HDGAGIYNDLPQHLEIMRYHSLMVQADTLPDCLTVTAVVANDEHNDLELTESALAGDEIM
ECCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHEEEEEEECCCCCCHHHHHHHHCCCHHC
GVQHKDYPIQGVQFHPESFATEGAKRLLTNFLLQV
CCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNVLIIDNYDSFTFNLYQYIGEILQTMDSDKQANVIVKRNNEITLADVQAMSLDRIIISP
CEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEEEEHEEEECEEEECC
GPGSPDDPAYFGICAEVIEVMGKTTPLLGVCLGMQGIAHVFGGDVIRASVPMHGKVSAIR
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEE
HDGAGIYNDLPQHLEIMRYHSLMVQADTLPDCLTVTAVVANDEHNDLELTESALAGDEIM
ECCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHEEEEEEECCCCCCHHHHHHHHCCCHHC
GVQHKDYPIQGVQFHPESFATEGAKRLLTNFLLQV
CCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703466 [H]