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The map label for this gene is yedW [H]

Identifier: 93006072

GI number: 93006072

Start: 1515024

End: 1515710

Strand: Reverse

Name: yedW [H]

Synonym: Pcryo_1244

Alternate gene names: 93006072

Gene position: 1515710-1515024 (Counterclockwise)

Preceding gene: 93006073

Following gene: 93006071

Centisome position: 49.54

GC content: 42.36

Gene sequence:

>687_bases
ATGTATAAGATACTTATTATTGAAGACAATCCTGATATCGTAGCCAATATCTATGCTTTTTTTGAGCCAAAAGGTTTCGA
GTTGGACAATGCCCATAATAGTCTGAGTGGCTTGGCACTGGCTTCAAGCAATCGCTACGATGTTATATTGCTCGACGTGA
TGCTTCCCGGTATGGATGGTACTAAGCTGTGCAAAACGCTTAGAGAAGAGCTGCATGATAAGACGCCCGTATTGATGCTG
ACCGCGCGTGATACTGTTTTGGATAAGGTTGCAGGGTTTGATAGTGGTGCGGATGATTATTTGGTCAAACCTTTCTCATT
GGTTGAATTAGAAGCTCGCATCAAAGCATTAATACGCCGCCATCAAGATGAACATTTTCAGCACAATATAGAAGTTGGCA
AGCTGTCTCTAAATACTGAGGAACACAGTATCAAACGAGAAGACAAACCATTAAAACTAACCCCAACGGGATTCAAAATC
TTACACACTCTGATGATTGCCTCGCCTCGGGTAGTCAGTAAAACTGAGCTTGAGGAAAAAGTATGGGGACAAGATGTGCC
AAGTAGTGATGCGCTTCGCACCCATTTGCATAGTGTGCGTGCGCAAGTTGATAAACCGTTTGATAAAGTCATGATAGTAA
CAATGGCTGGTGTTGGTTACCAAATTATTGACCCAGACAAAGTTTGA

Upstream 100 bases:

>100_bases
TGGTATCACTACTCAAGAAGTAGCGTCAGAACCCACCTTTTTTAAGACTACCCATTAAACTTTTTTATTCAATTCACACT
TTTTGTAGATAGTAGCCATT

Downstream 100 bases:

>100_bases
AAATTCATAATACAATTTAAAGATTGAAGTTTACTATAAGTAGTTACGCCCGTACTTCCCTATCTATTACCTGACTCTAA
ATAAGCACCTGCCATGTTCA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MYKILIIEDNPDIVANIYAFFEPKGFELDNAHNSLSGLALASSNRYDVILLDVMLPGMDGTKLCKTLREELHDKTPVLML
TARDTVLDKVAGFDSGADDYLVKPFSLVELEARIKALIRRHQDEHFQHNIEVGKLSLNTEEHSIKREDKPLKLTPTGFKI
LHTLMIASPRVVSKTELEEKVWGQDVPSSDALRTHLHSVRAQVDKPFDKVMIVTMAGVGYQIIDPDKV

Sequences:

>Translated_228_residues
MYKILIIEDNPDIVANIYAFFEPKGFELDNAHNSLSGLALASSNRYDVILLDVMLPGMDGTKLCKTLREELHDKTPVLML
TARDTVLDKVAGFDSGADDYLVKPFSLVELEARIKALIRRHQDEHFQHNIEVGKLSLNTEEHSIKREDKPLKLTPTGFKI
LHTLMIASPRVVSKTELEEKVWGQDVPSSDALRTHLHSVRAQVDKPFDKVMIVTMAGVGYQIIDPDKV
>Mature_228_residues
MYKILIIEDNPDIVANIYAFFEPKGFELDNAHNSLSGLALASSNRYDVILLDVMLPGMDGTKLCKTLREELHDKTPVLML
TARDTVLDKVAGFDSGADDYLVKPFSLVELEARIKALIRRHQDEHFQHNIEVGKLSLNTEEHSIKREDKPLKLTPTGFKI
LHTLMIASPRVVSKTELEEKVWGQDVPSSDALRTHLHSVRAQVDKPFDKVMIVTMAGVGYQIIDPDKV

Specific function: Probable member of a two-component regulatory system yedW/yedV [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=37.3873873873874, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=37.3873873873874, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=35.5855855855856, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=36.036036036036, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=32.4444444444444, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=31.1965811965812, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=30.9734513274336, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=34.5291479820628, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=35.7758620689655, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=28.3783783783784, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=28, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=27.3542600896861, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=26.0869565217391, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=37.037037037037, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790299, Length=129, Percent_Identity=27.906976744186, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25673; Mature: 25673

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKILIIEDNPDIVANIYAFFEPKGFELDNAHNSLSGLALASSNRYDVILLDVMLPGMDG
CEEEEEEECCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEECCCCCH
TKLCKTLREELHDKTPVLMLTARDTVLDKVAGFDSGADDYLVKPFSLVELEARIKALIRR
HHHHHHHHHHHCCCCCEEEEEECHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHH
HQDEHFQHNIEVGKLSLNTEEHSIKREDKPLKLTPTGFKILHTLMIASPRVVSKTELEEK
HCHHHHHCCCEEEEEEECCHHHHHHCCCCCEEECCCHHHHHHHHHHCCCCCCCHHHHHHH
VWGQDVPSSDALRTHLHSVRAQVDKPFDKVMIVTMAGVGYQIIDPDKV
HCCCCCCCHHHHHHHHHHHHHHHCCCHHHEEEEEECCCCEEEECCCCC
>Mature Secondary Structure
MYKILIIEDNPDIVANIYAFFEPKGFELDNAHNSLSGLALASSNRYDVILLDVMLPGMDG
CEEEEEEECCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEECCCCCH
TKLCKTLREELHDKTPVLMLTARDTVLDKVAGFDSGADDYLVKPFSLVELEARIKALIRR
HHHHHHHHHHHCCCCCEEEEEECHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHH
HQDEHFQHNIEVGKLSLNTEEHSIKREDKPLKLTPTGFKILHTLMIASPRVVSKTELEEK
HCHHHHHCCCEEEEEEECCHHHHHHCCCCCEEECCCHHHHHHHHHHCCCCCCCHHHHHHH
VWGQDVPSSDALRTHLHSVRAQVDKPFDKVMIVTMAGVGYQIIDPDKV
HCCCCCCCHHHHHHHHHHHHHHHCCCHHHEEEEEECCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]