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The map label for this gene is insK [H]

Identifier: 93005578

GI number: 93005578

Start: 880839

End: 881597

Strand: Direct

Name: insK [H]

Synonym: Pcryo_0748

Alternate gene names: 93005578

Gene position: 880839-881597 (Clockwise)

Preceding gene: 93005577

Following gene: 93005579

Centisome position: 28.79

GC content: 41.37

Gene sequence:

>759_bases
GTGCATGCATTAAAAGCTGATGATAAGTATGCCGATCTTAAACAGCGTATCAGTGACATCTATCATTACCATAAAGGTCG
ATATGGCTATCGTAGAATCACTCAAACGCTTAAGAACGAAGGAATAAGATACAACCACAAGCTCATCGCACGGCTTATGA
ACGAGCTTAAACTTACCGCGAGAATCAGACGACAGAAGTATCGATCCTATAAAGGTCAGTGTGGCGTCATTGCCAAGAAT
AGAGTCAAACGCAGGTTCAGAGCGAAAGCGCCCAATCGCAGGTGGTTTACTGACATCACAGAGTTTAAAGTCGGTGATGA
GAAGTTGTATCTGTCTCCTATACTAGACTGCTTCAACAATGAGATCATCAGTTATACGCTCTCAAGACGACCCGTATATG
ACTTGGTGAAACAGATGCTAGATAGTGCACTTAAGGGCATACCTACAAAGCGCAAGGAGACACTGACGCTGCATTCAGAT
CAAGGGTGGCACTATCAGATAAAACCGTTTGCGACAACGCTTGAAACGCATAAAATTAAACAGAGTATGAGTAGAAAAGG
CAACTGCTTAGACAATGCGCTGATGGAGAGCTTCTTCGGTACGCTAAAATGTGAAACTATTTATATTGAAAAGCCATCGA
GTATTGAGGCTTTAGAGAAACAGATTCATAACTTTATGCTCTACTACAATCATGAGAGAATTCAGATGAAACTAAAAGGA
CTAAGCCCTGTACAATACAGAACTCAGTCCTTGATTTAA

Upstream 100 bases:

>100_bases
ATCAGACAAAGCAAGGCTCGTCAAAGGACTAAGAGATCAGCATCCGCTAGCTTTACTATTACTCATTGCAGATATAGCAA
GAAGCAGCTTTTACTATCAT

Downstream 100 bases:

>100_bases
TTAAACTGTCCAAGTTTAGGGGGTCAGTTCAATTGATTGCGGGGTTTTTTGCTGTGAGCAATGGCTGGTTTCTCTTATTA
TCTTATGTATAATATGGGAG

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MHALKADDKYADLKQRISDIYHYHKGRYGYRRITQTLKNEGIRYNHKLIARLMNELKLTARIRRQKYRSYKGQCGVIAKN
RVKRRFRAKAPNRRWFTDITEFKVGDEKLYLSPILDCFNNEIISYTLSRRPVYDLVKQMLDSALKGIPTKRKETLTLHSD
QGWHYQIKPFATTLETHKIKQSMSRKGNCLDNALMESFFGTLKCETIYIEKPSSIEALEKQIHNFMLYYNHERIQMKLKG
LSPVQYRTQSLI

Sequences:

>Translated_252_residues
MHALKADDKYADLKQRISDIYHYHKGRYGYRRITQTLKNEGIRYNHKLIARLMNELKLTARIRRQKYRSYKGQCGVIAKN
RVKRRFRAKAPNRRWFTDITEFKVGDEKLYLSPILDCFNNEIISYTLSRRPVYDLVKQMLDSALKGIPTKRKETLTLHSD
QGWHYQIKPFATTLETHKIKQSMSRKGNCLDNALMESFFGTLKCETIYIEKPSSIEALEKQIHNFMLYYNHERIQMKLKG
LSPVQYRTQSLI
>Mature_252_residues
MHALKADDKYADLKQRISDIYHYHKGRYGYRRITQTLKNEGIRYNHKLIARLMNELKLTARIRRQKYRSYKGQCGVIAKN
RVKRRFRAKAPNRRWFTDITEFKVGDEKLYLSPILDCFNNEIISYTLSRRPVYDLVKQMLDSALKGIPTKRKETLTLHSD
QGWHYQIKPFATTLETHKIKQSMSRKGNCLDNALMESFFGTLKCETIYIEKPSSIEALEKQIHNFMLYYNHERIQMKLKG
LSPVQYRTQSLI

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=228, Percent_Identity=29.8245614035088, Blast_Score=92, Evalue=4e-19,
Organism=Escherichia coli, GI1789981, Length=250, Percent_Identity=52.8, Blast_Score=282, Evalue=2e-77,
Organism=Escherichia coli, GI1788405, Length=229, Percent_Identity=32.3144104803493, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1787263, Length=229, Percent_Identity=32.3144104803493, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1786753, Length=229, Percent_Identity=32.3144104803493, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1786570, Length=229, Percent_Identity=32.3144104803493, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1786490, Length=229, Percent_Identity=32.3144104803493, Blast_Score=119, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 29961; Mature: 29961

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHALKADDKYADLKQRISDIYHYHKGRYGYRRITQTLKNEGIRYNHKLIARLMNELKLTA
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RIRRQKYRSYKGQCGVIAKNRVKRRFRAKAPNRRWFTDITEFKVGDEKLYLSPILDCFNN
HHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCC
EIISYTLSRRPVYDLVKQMLDSALKGIPTKRKETLTLHSDQGWHYQIKPFATTLETHKIK
HHEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEECHHHHHHHHHHHH
QSMSRKGNCLDNALMESFFGTLKCETIYIEKPSSIEALEKQIHNFMLYYNHERIQMKLKG
HHHHHCCCHHHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHEECCCEEEEEECC
LSPVQYRTQSLI
CCCHHHHHHHCC
>Mature Secondary Structure
MHALKADDKYADLKQRISDIYHYHKGRYGYRRITQTLKNEGIRYNHKLIARLMNELKLTA
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RIRRQKYRSYKGQCGVIAKNRVKRRFRAKAPNRRWFTDITEFKVGDEKLYLSPILDCFNN
HHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCC
EIISYTLSRRPVYDLVKQMLDSALKGIPTKRKETLTLHSDQGWHYQIKPFATTLETHKIK
HHEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEECHHHHHHHHHHHH
QSMSRKGNCLDNALMESFFGTLKCETIYIEKPSSIEALEKQIHNFMLYYNHERIQMKLKG
HHHHHCCCHHHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHEECCCEEEEEECC
LSPVQYRTQSLI
CCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]