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The map label for this gene is ucpA [C]

Identifier: 93005557

GI number: 93005557

Start: 856187

End: 856924

Strand: Direct

Name: ucpA [C]

Synonym: Pcryo_0727

Alternate gene names: 93005557

Gene position: 856187-856924 (Clockwise)

Preceding gene: 93005550

Following gene: 93005558

Centisome position: 27.98

GC content: 43.09

Gene sequence:

>738_bases
ATGACAGACACTGCTAAGAAACAACATATTGTGATCACGGGTGCGACCTCTGGGATTGGTTATCAGCTGGCAAAAGACTA
TCTGCGAGAGGGACAGCATGTCTATGCCGTCGGTCGCGATGAGGAAGCCTTGTCTGAGCTAAAATCATTAGGAGCAGAAA
CTGTCGATTTAGATCTAATGGATCGAGATAAGGTGATTGCTGCTTTTGATAAAATTAATGAGATTGATTTGGCGATTTGC
GGCGCTGGCATGTGTGAGTATCTAGATATGCCAAACTTTGATAGCACGGCATTTATGAAAGTGCTGTCGGTGAATATGGG
TACGTTATCGCATGCCATTGAAGCAGTACTGCCAAAGCTGATTGCTTCAAAAGGACGCTTAGTTGGTATTGGCTCGGCGT
CGGCTTACGTGCCTTTTGCTCGTGCAGAGGCTTATGGTAGCTCAAAAGCAGCTATTCACTATTTAATGAAAACTTTACAG
ATTAGCCTTGCACCGCAAGGTGTAGCAGTCAGCTTAGTAGTTCCCGGCTTTGTAGAGACGCCAATGACCAAACAAAACGA
TTTTCCGATGCCGTTTTTACAGACTACACAGCAGGCAAGTCAAGCGATTCGTGACGGTATAAAAAGTGGCAATGACGTTA
TTGAATTTCCCAAAAAACTGACGTTACCATTAAAAGTATTAGGGACATTACCTGATATAGTTTGGCAACAGGTCAGTACA
AAAATCAATAAAAAATAG

Upstream 100 bases:

>100_bases
ACATTGTTAATAGCTATAAAGCTGCTAAAGGCTTATCAGATAAAGATTTATCAAAGCCAAACCAAGAATAAGATAGCAAA
CGACGAAAAGGACATTTGCG

Downstream 100 bases:

>100_bases
CCAGTTTTAGTATTTTTGAACACCTATAAAGAAAATAACTAGGAATATTTTATGCCGTTTTTACGCCGTAAATCTAAGCA
GCTATCTAATCAAGTAGAAG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MTDTAKKQHIVITGATSGIGYQLAKDYLREGQHVYAVGRDEEALSELKSLGAETVDLDLMDRDKVIAAFDKINEIDLAIC
GAGMCEYLDMPNFDSTAFMKVLSVNMGTLSHAIEAVLPKLIASKGRLVGIGSASAYVPFARAEAYGSSKAAIHYLMKTLQ
ISLAPQGVAVSLVVPGFVETPMTKQNDFPMPFLQTTQQASQAIRDGIKSGNDVIEFPKKLTLPLKVLGTLPDIVWQQVST
KINKK

Sequences:

>Translated_245_residues
MTDTAKKQHIVITGATSGIGYQLAKDYLREGQHVYAVGRDEEALSELKSLGAETVDLDLMDRDKVIAAFDKINEIDLAIC
GAGMCEYLDMPNFDSTAFMKVLSVNMGTLSHAIEAVLPKLIASKGRLVGIGSASAYVPFARAEAYGSSKAAIHYLMKTLQ
ISLAPQGVAVSLVVPGFVETPMTKQNDFPMPFLQTTQQASQAIRDGIKSGNDVIEFPKKLTLPLKVLGTLPDIVWQQVST
KINKK
>Mature_244_residues
TDTAKKQHIVITGATSGIGYQLAKDYLREGQHVYAVGRDEEALSELKSLGAETVDLDLMDRDKVIAAFDKINEIDLAICG
AGMCEYLDMPNFDSTAFMKVLSVNMGTLSHAIEAVLPKLIASKGRLVGIGSASAYVPFARAEAYGSSKAAIHYLMKTLQI
SLAPQGVAVSLVVPGFVETPMTKQNDFPMPFLQTTQQASQAIRDGIKSGNDVIEFPKKLTLPLKVLGTLPDIVWQQVSTK
INKK

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI33667109, Length=239, Percent_Identity=27.1966527196653, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5031737, Length=190, Percent_Identity=30, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI7705855, Length=193, Percent_Identity=27.4611398963731, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI226371731, Length=194, Percent_Identity=25.7731958762887, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI119392083, Length=183, Percent_Identity=30.6010928961749, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI223718074, Length=186, Percent_Identity=30.1075268817204, Blast_Score=64, Evalue=8e-11,
Organism=Homo sapiens, GI4503817, Length=230, Percent_Identity=25.2173913043478, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI87082100, Length=189, Percent_Identity=32.2751322751323, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1787820, Length=178, Percent_Identity=28.0898876404494, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI2367365, Length=186, Percent_Identity=27.4193548387097, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786701, Length=203, Percent_Identity=28.0788177339901, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=182, Percent_Identity=24.1758241758242, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=190, Percent_Identity=30.5263157894737, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=189, Percent_Identity=31.2169312169312, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560176, Length=203, Percent_Identity=25.615763546798, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=228, Percent_Identity=29.3859649122807, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=223, Percent_Identity=24.6636771300448, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=186, Percent_Identity=25.8064516129032, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=218, Percent_Identity=26.1467889908257, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=196, Percent_Identity=29.5918367346939, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322227, Length=192, Percent_Identity=29.6875, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI23397609, Length=182, Percent_Identity=35.7142857142857, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24584744, Length=198, Percent_Identity=31.3131313131313, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28574402, Length=198, Percent_Identity=31.3131313131313, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI161076933, Length=189, Percent_Identity=29.6296296296296, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24584748, Length=189, Percent_Identity=29.6296296296296, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357041, Length=191, Percent_Identity=29.3193717277487, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28571526, Length=191, Percent_Identity=29.8429319371728, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24640442, Length=193, Percent_Identity=26.9430051813472, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24643142, Length=193, Percent_Identity=30.0518134715026, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26506; Mature: 26375

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTAKKQHIVITGATSGIGYQLAKDYLREGQHVYAVGRDEEALSELKSLGAETVDLDLM
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCEEEEEEC
DRDKVIAAFDKINEIDLAICGAGMCEYLDMPNFDSTAFMKVLSVNMGTLSHAIEAVLPKL
CCCHHHHHHHCCCHHHHEEECCCHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
IASKGRLVGIGSASAYVPFARAEAYGSSKAAIHYLMKTLQISLAPQGVAVSLVVPGFVET
HHCCCCEEEECCCCHHCCHHHHHHCCCHHHHHHHHHHHHHHEECCCCEEEEEEECCCCCC
PMTKQNDFPMPFLQTTQQASQAIRDGIKSGNDVIEFPKKLTLPLKVLGTLPDIVWQQVST
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHCCHHHHHHHHHHHHHHHHHH
KINKK
HHCCC
>Mature Secondary Structure 
TDTAKKQHIVITGATSGIGYQLAKDYLREGQHVYAVGRDEEALSELKSLGAETVDLDLM
CCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCEEEEEEC
DRDKVIAAFDKINEIDLAICGAGMCEYLDMPNFDSTAFMKVLSVNMGTLSHAIEAVLPKL
CCCHHHHHHHCCCHHHHEEECCCHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
IASKGRLVGIGSASAYVPFARAEAYGSSKAAIHYLMKTLQISLAPQGVAVSLVVPGFVET
HHCCCCEEEECCCCHHCCHHHHHHCCCHHHHHHHHHHHHHHEECCCCEEEEEEECCCCCC
PMTKQNDFPMPFLQTTQQASQAIRDGIKSGNDVIEFPKKLTLPLKVLGTLPDIVWQQVST
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHCCHHHHHHHHHHHHHHHHHH
KINKK
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730672 [H]