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The map label for this gene is fba [H]

Identifier: 93005513

GI number: 93005513

Start: 809722

End: 810759

Strand: Direct

Name: fba [H]

Synonym: Pcryo_0683

Alternate gene names: 93005513

Gene position: 809722-810759 (Clockwise)

Preceding gene: 93005512

Following gene: 93005514

Centisome position: 26.46

GC content: 46.24

Gene sequence:

>1038_bases
ATGGCCTTAATATCGTTACGTCAACTTTTGGATCATGCTGCTGAACACGGCTATGGTGTTCCTGCTTACAATGTTAATAA
TTTAGAGCAGATGCGTGCCATTATGATGGCGGCTGACGCCTGTGACTCTCCTGTGATTGTACAAGCCAGTGCCGGTGCCC
GTAGTTATGCAGGCTCTGCGTTTTTGCGTCATCTGATTATTGCTGCTATCGAAGAGTGGCCACATATTCCAGTCGTTATG
CATCAAGATCACGGTATGTCACCTGCTATTTGCCAACGCTCAATTCAGCTTGGCTTCTCATCAGTGATGATGGACGGCTC
GCTTGGTACAGACGGTAAAACGCCGATGGATTATGACTATAACGCTAGCGTGACTCGCGAAGTAGTCAAGATGGCTCATG
CTTGCGGTGTTTCAGTCGAAGGCGAGATTGGTTGCTTAGGTAGTCTTGAAACTGGTATGGCAGGCGAAGAAGATGGCTCT
GGCGCAGAAGGCGTATTGGATCACGAGCAGCTATTGACCAGTGCTGATGAAGCAGAGCAGTTCGTTAAAGACACCAACGT
CGATGCGTTAGCGATTGCTATCGGTACCAGTCATGGTGCTTATAAGTTTACGCGTCCACCGACAGGCGATATCTTATCGA
TTGAGCGCGTAAAGGAGATTCATGCCCGTATTCCTAACACTCACCTAGTCATGCATGGTTCATCATCAGTACCGCAAGAA
TGGCTAAAAGTCATCAATGAAAATGGTGGCAACATCGGTGAGACTTATGGTGTACCGGTTGAGCAAATCGTTGAAGCGAT
TAAGCATGGTGTGCGTAAAGTAAATATCGATACCGATTTACGTTTGGCATCAACTGGCGCTATCCGTAAATTCCTTGCAG
AAAATCCGAGTGAATTTGATCCACGTAAATATTTCAAAGCCTCTATGGTTGCGATGTCAGATATCTGTGCCAATCGTTTT
GAAGCCTTTGGTTCAGCGGGTCAAGCGCATAAAATTCGTCCAATCAGTCTTGAAGGTATGGTTAATTTTTACCCGTAA

Upstream 100 bases:

>100_bases
CTAGGTCGCAGTGCAAATGTGGCAACGTCTTATTGTTAAAAATGATGTTTTAATATCATCTTCAAAATACTATTTTTAGA
ATATAACCAGAGAGCGTTTT

Downstream 100 bases:

>100_bases
GCTTAGAGGGTAAAAGATAGTGCTTGATGTCTAGGTCATGGCTTAACCCATTTTTTATAATATAGTCAGATGAAAATAAA
AATGTTATGAAAATTTAAAC

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MALISLRQLLDHAAEHGYGVPAYNVNNLEQMRAIMMAADACDSPVIVQASAGARSYAGSAFLRHLIIAAIEEWPHIPVVM
HQDHGMSPAICQRSIQLGFSSVMMDGSLGTDGKTPMDYDYNASVTREVVKMAHACGVSVEGEIGCLGSLETGMAGEEDGS
GAEGVLDHEQLLTSADEAEQFVKDTNVDALAIAIGTSHGAYKFTRPPTGDILSIERVKEIHARIPNTHLVMHGSSSVPQE
WLKVINENGGNIGETYGVPVEQIVEAIKHGVRKVNIDTDLRLASTGAIRKFLAENPSEFDPRKYFKASMVAMSDICANRF
EAFGSAGQAHKIRPISLEGMVNFYP

Sequences:

>Translated_345_residues
MALISLRQLLDHAAEHGYGVPAYNVNNLEQMRAIMMAADACDSPVIVQASAGARSYAGSAFLRHLIIAAIEEWPHIPVVM
HQDHGMSPAICQRSIQLGFSSVMMDGSLGTDGKTPMDYDYNASVTREVVKMAHACGVSVEGEIGCLGSLETGMAGEEDGS
GAEGVLDHEQLLTSADEAEQFVKDTNVDALAIAIGTSHGAYKFTRPPTGDILSIERVKEIHARIPNTHLVMHGSSSVPQE
WLKVINENGGNIGETYGVPVEQIVEAIKHGVRKVNIDTDLRLASTGAIRKFLAENPSEFDPRKYFKASMVAMSDICANRF
EAFGSAGQAHKIRPISLEGMVNFYP
>Mature_344_residues
ALISLRQLLDHAAEHGYGVPAYNVNNLEQMRAIMMAADACDSPVIVQASAGARSYAGSAFLRHLIIAAIEEWPHIPVVMH
QDHGMSPAICQRSIQLGFSSVMMDGSLGTDGKTPMDYDYNASVTREVVKMAHACGVSVEGEIGCLGSLETGMAGEEDGSG
AEGVLDHEQLLTSADEAEQFVKDTNVDALAIAIGTSHGAYKFTRPPTGDILSIERVKEIHARIPNTHLVMHGSSSVPQEW
LKVINENGGNIGETYGVPVEQIVEAIKHGVRKVNIDTDLRLASTGAIRKFLAENPSEFDPRKYFKASMVAMSDICANRFE
AFGSAGQAHKIRPISLEGMVNFYP

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=328, Percent_Identity=31.4024390243902, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI87082041, Length=329, Percent_Identity=31.0030395136778, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1788072, Length=330, Percent_Identity=27.2727272727273, Blast_Score=105, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006412
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 37209; Mature: 37077

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALISLRQLLDHAAEHGYGVPAYNVNNLEQMRAIMMAADACDSPVIVQASAGARSYAGSA
CHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHH
FLRHLIIAAIEEWPHIPVVMHQDHGMSPAICQRSIQLGFSSVMMDGSLGTDGKTPMDYDY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCHHHHEECCCCCCCCCCCCCCCC
NASVTREVVKMAHACGVSVEGEIGCLGSLETGMAGEEDGSGAEGVLDHEQLLTSADEAEQ
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FVKDTNVDALAIAIGTSHGAYKFTRPPTGDILSIERVKEIHARIPNTHLVMHGSSSVPQE
HHHHCCCCEEEEEEECCCCCEEECCCCCCCEEHHHHHHHHHHHCCCCEEEEECCCCCHHH
WLKVINENGGNIGETYGVPVEQIVEAIKHGVRKVNIDTDLRLASTGAIRKFLAENPSEFD
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCEEHHHHHHHHHHHCCCCCCC
PRKYFKASMVAMSDICANRFEAFGSAGQAHKIRPISLEGMVNFYP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEECCC
>Mature Secondary Structure 
ALISLRQLLDHAAEHGYGVPAYNVNNLEQMRAIMMAADACDSPVIVQASAGARSYAGSA
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHH
FLRHLIIAAIEEWPHIPVVMHQDHGMSPAICQRSIQLGFSSVMMDGSLGTDGKTPMDYDY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCHHHHEECCCCCCCCCCCCCCCC
NASVTREVVKMAHACGVSVEGEIGCLGSLETGMAGEEDGSGAEGVLDHEQLLTSADEAEQ
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FVKDTNVDALAIAIGTSHGAYKFTRPPTGDILSIERVKEIHARIPNTHLVMHGSSSVPQE
HHHHCCCCEEEEEEECCCCCEEECCCCCCCEEHHHHHHHHHHHCCCCEEEEECCCCCHHH
WLKVINENGGNIGETYGVPVEQIVEAIKHGVRKVNIDTDLRLASTGAIRKFLAENPSEFD
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCEEHHHHHHHHHHHCCCCCCC
PRKYFKASMVAMSDICANRFEAFGSAGQAHKIRPISLEGMVNFYP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]