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The map label for this gene is ahpC [C]

Identifier: 93005497

GI number: 93005497

Start: 790649

End: 791287

Strand: Direct

Name: ahpC [C]

Synonym: Pcryo_0667

Alternate gene names: 93005497

Gene position: 790649-791287 (Clockwise)

Preceding gene: 93005496

Following gene: 93005498

Centisome position: 25.84

GC content: 44.6

Gene sequence:

>639_bases
ATGGCACATTTACGTTTAGGCGATACCGCACCAAATTTTGATGCAACCACTACTGAAGGTGATATCAATTTCCATGAATG
GGCGGGTGATAATTGGGTGGTTTTCTTCTCACATCCAGCCGATTTTACCCCAGTATGTACCACTGAGCTCGGTCGTGCTG
CTGCGCTAAATGGCGAATTTCAAAAGCGCGGCGTGAAGCCAATTTGTATCTCTGTTGACGGTATCGATGACCATCATGCC
TGGGCAAAAGATATCGGTGAAACTCAAGGTACTGAACTGAACTTCCCCATCATCGCTGATCCTAATAAAGAAGTGGCTGA
GCTGTATGACATGATGCATCCAAATGCAGACAGCACGCATACCGTACGTAGCGTCTTTATTATTGACCCAAGCAAAAAGA
TTCGACTAACACTGACCTATCCTGCTAGCTGTGGACGTAACTTTGACGAGATTCTTCGTGTGATTGACGCACTGCAATTG
TCTGATGAATACAACATCGCAACGCCAGTAGACTGGAAAGATGGTGATGACGTTATCATTCCGCCAAGTGTTAAAAACGA
AGATATCGCTGCCAAATATCCAAAAGGTCACACAGAAATTAAGCCGTATCTACGTACCACTCCTGCACCTAATAAATAA

Upstream 100 bases:

>100_bases
GGTAGATATTTTAACCGCTGAGTATGTCGTTGATAATAAGAGAGCGCGTAGATAGCATTCGATAATAGCGCTCGTCACAA
TCATAAATAAGGAATCAAGC

Downstream 100 bases:

>100_bases
TAAGCTGGAGCATGTGAGCTTGATGAAGAGATGATTTAAAAAGCCCCATAATGCAAAATTGTGGGGCTTTCTGTTATTCA
GCTTAACATCAGAAGCATCA

Product: peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MAHLRLGDTAPNFDATTTEGDINFHEWAGDNWVVFFSHPADFTPVCTTELGRAAALNGEFQKRGVKPICISVDGIDDHHA
WAKDIGETQGTELNFPIIADPNKEVAELYDMMHPNADSTHTVRSVFIIDPSKKIRLTLTYPASCGRNFDEILRVIDALQL
SDEYNIATPVDWKDGDDVIIPPSVKNEDIAAKYPKGHTEIKPYLRTTPAPNK

Sequences:

>Translated_212_residues
MAHLRLGDTAPNFDATTTEGDINFHEWAGDNWVVFFSHPADFTPVCTTELGRAAALNGEFQKRGVKPICISVDGIDDHHA
WAKDIGETQGTELNFPIIADPNKEVAELYDMMHPNADSTHTVRSVFIIDPSKKIRLTLTYPASCGRNFDEILRVIDALQL
SDEYNIATPVDWKDGDDVIIPPSVKNEDIAAKYPKGHTEIKPYLRTTPAPNK
>Mature_211_residues
AHLRLGDTAPNFDATTTEGDINFHEWAGDNWVVFFSHPADFTPVCTTELGRAAALNGEFQKRGVKPICISVDGIDDHHAW
AKDIGETQGTELNFPIIADPNKEVAELYDMMHPNADSTHTVRSVFIIDPSKKIRLTLTYPASCGRNFDEILRVIDALQLS
DEYNIATPVDWKDGDDVIIPPSVKNEDIAAKYPKGHTEIKPYLRTTPAPNK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=220, Percent_Identity=52.2727272727273, Blast_Score=222, Evalue=2e-58,
Organism=Homo sapiens, GI4505591, Length=194, Percent_Identity=33.5051546391753, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI32455266, Length=194, Percent_Identity=33.5051546391753, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI32455264, Length=194, Percent_Identity=33.5051546391753, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI32189392, Length=198, Percent_Identity=32.8282828282828, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI5453549, Length=152, Percent_Identity=32.2368421052632, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5802974, Length=184, Percent_Identity=27.7173913043478, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI32483377, Length=188, Percent_Identity=26.5957446808511, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI1786822, Length=152, Percent_Identity=33.5526315789474, Blast_Score=77, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI25153706, Length=218, Percent_Identity=38.5321100917431, Blast_Score=159, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17554494, Length=193, Percent_Identity=31.6062176165803, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI193204376, Length=198, Percent_Identity=29.2929292929293, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32565831, Length=198, Percent_Identity=29.2929292929293, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319407, Length=214, Percent_Identity=53.7383177570093, Blast_Score=225, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6323613, Length=183, Percent_Identity=28.4153005464481, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24581278, Length=217, Percent_Identity=50.2304147465438, Blast_Score=219, Evalue=7e-58,
Organism=Drosophila melanogaster, GI24652434, Length=217, Percent_Identity=46.5437788018433, Blast_Score=193, Evalue=9e-50,
Organism=Drosophila melanogaster, GI17975518, Length=217, Percent_Identity=46.5437788018433, Blast_Score=192, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24652436, Length=217, Percent_Identity=46.5437788018433, Blast_Score=192, Evalue=1e-49,
Organism=Drosophila melanogaster, GI21357347, Length=193, Percent_Identity=32.1243523316062, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17157991, Length=189, Percent_Identity=29.1005291005291, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641739, Length=189, Percent_Identity=29.1005291005291, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24656348, Length=177, Percent_Identity=28.8135593220339, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17864676, Length=177, Percent_Identity=28.8135593220339, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17738015, Length=203, Percent_Identity=27.0935960591133, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23573; Mature: 23441

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHLRLGDTAPNFDATTTEGDINFHEWAGDNWVVFFSHPADFTPVCTTELGRAAALNGEF
CCEEECCCCCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCHHHHCCCEEECCCHH
QKRGVKPICISVDGIDDHHAWAKDIGETQGTELNFPIIADPNKEVAELYDMMHPNADSTH
HHCCCCEEEEEECCCCCHHHHHHHHCCCCCCEECCCEEECCCHHHHHHHHHHCCCCCCCE
TVRSVFIIDPSKKIRLTLTYPASCGRNFDEILRVIDALQLSDEYNIATPVDWKDGDDVII
EEEEEEEECCCCEEEEEEEECHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
PPSVKNEDIAAKYPKGHTEIKPYLRTTPAPNK
CCCCCCCCCEECCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure 
AHLRLGDTAPNFDATTTEGDINFHEWAGDNWVVFFSHPADFTPVCTTELGRAAALNGEF
CEEECCCCCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCHHHHCCCEEECCCHH
QKRGVKPICISVDGIDDHHAWAKDIGETQGTELNFPIIADPNKEVAELYDMMHPNADSTH
HHCCCCEEEEEECCCCCHHHHHHHHCCCCCCEECCCEEECCCHHHHHHHHHHCCCCCCCE
TVRSVFIIDPSKKIRLTLTYPASCGRNFDEILRVIDALQLSDEYNIATPVDWKDGDDVII
EEEEEEEECCCCEEEEEEEECHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
PPSVKNEDIAAKYPKGHTEIKPYLRTTPAPNK
CCCCCCCCCEECCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]