Click here to switch to the map view.

The map label for this gene is lpxA [H]

Identifier: 93005445

GI number: 93005445

Start: 732694

End: 733254

Strand: Direct

Name: lpxA [H]

Synonym: Pcryo_0615

Alternate gene names: 93005445

Gene position: 732694-733254 (Clockwise)

Preceding gene: 93005444

Following gene: 93005446

Centisome position: 23.95

GC content: 37.97

Gene sequence:

>561_bases
ATGAATAATAATGCGCAAATACACCCTTCAGCAGTAATTCATGAAGGCGTTATCATTGAAGATGATGTTTATATAGGTCC
CAACTGTATCATTGGCTATCCACCCGAAGATAAAGCTGTGTTTCCTCAAACGCCATACACCGTTCATATATGTTCAGGTA
CGAAAATTACAGGAAATGTGACTATTGATGCTGGAACTATCAAAAACACATACATCGGAAATGATTGCTTTTTAATGAAA
GGTGCTTATGTAGCACATGATGTAGTGATTGGGAATAATGTCACTCTATCTAGCCATGTTATGCTTGGAGGCCATGTAGA
AGTCATGGAGGGCGCTAACTTAGGTATGGGCTGTATTATTCATCAGCGTCAAAAAATTTGGCATTATTGCATGATAGGTA
TGGGTGCAATTGTCACTAAAAAACTAGTTATTGAGCCTTTCTCTATATACGTTGGCAACCCAGCAAAGAAAATAGGAACG
AATGATAAAGGTATTGAGAAAAGTGGGATTGACGAAAGAGCAATGGCTACTATACAAGAAGAATTCAACGCAAGAAGGTA
A

Upstream 100 bases:

>100_bases
GGCGTCAAAACCGTGGAACACATTCGTCATGCCAAAGACTCTACTACAGATGAGTCTAGGCTACACCCGAATGTCAAAAA
ACTATTGTTAGGATAGTAAG

Downstream 100 bases:

>100_bases
TGATGATGCAGTTTATTGATTTAGTCGCTCAGCAGGATAGGATAAAAGATAAATTAAATACCAATATCCAAAAGGTATTG
GCTCATGGTCAATATATTTT

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MNNNAQIHPSAVIHEGVIIEDDVYIGPNCIIGYPPEDKAVFPQTPYTVHICSGTKITGNVTIDAGTIKNTYIGNDCFLMK
GAYVAHDVVIGNNVTLSSHVMLGGHVEVMEGANLGMGCIIHQRQKIWHYCMIGMGAIVTKKLVIEPFSIYVGNPAKKIGT
NDKGIEKSGIDERAMATIQEEFNARR

Sequences:

>Translated_186_residues
MNNNAQIHPSAVIHEGVIIEDDVYIGPNCIIGYPPEDKAVFPQTPYTVHICSGTKITGNVTIDAGTIKNTYIGNDCFLMK
GAYVAHDVVIGNNVTLSSHVMLGGHVEVMEGANLGMGCIIHQRQKIWHYCMIGMGAIVTKKLVIEPFSIYVGNPAKKIGT
NDKGIEKSGIDERAMATIQEEFNARR
>Mature_186_residues
MNNNAQIHPSAVIHEGVIIEDDVYIGPNCIIGYPPEDKAVFPQTPYTVHICSGTKITGNVTIDAGTIKNTYIGNDCFLMK
GAYVAHDVVIGNNVTLSSHVMLGGHVEVMEGANLGMGCIIHQRQKIWHYCMIGMGAIVTKKLVIEPFSIYVGNPAKKIGT
NDKGIEKSGIDERAMATIQEEFNARR

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=220, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 20242; Mature: 20242

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNAQIHPSAVIHEGVIIEDDVYIGPNCIIGYPPEDKAVFPQTPYTVHICSGTKITGNV
CCCCCEECCHHEEECCEEEECCEEECCCCEECCCCCCCEECCCCCCEEEEECCCEEEEEE
TIDAGTIKNTYIGNDCFLMKGAYVAHDVVIGNNVTLSSHVMLGGHVEVMEGANLGMGCII
EEECCCCCCEEECCEEEEEECCEEEEEEEECCCEEEECEEEECCEEEEEECCCCCEEEEE
HQRQKIWHYCMIGMGAIVTKKLVIEPFSIYVGNPAKKIGTNDKGIEKSGIDERAMATIQE
EHHHHHHHHHHHHCHHHHHHHEEECEEEEEECCCHHHCCCCCCCCCCCCCCHHHHHHHHH
EFNARR
HHCCCC
>Mature Secondary Structure
MNNNAQIHPSAVIHEGVIIEDDVYIGPNCIIGYPPEDKAVFPQTPYTVHICSGTKITGNV
CCCCCEECCHHEEECCEEEECCEEECCCCEECCCCCCCEECCCCCCEEEEECCCEEEEEE
TIDAGTIKNTYIGNDCFLMKGAYVAHDVVIGNNVTLSSHVMLGGHVEVMEGANLGMGCII
EEECCCCCCEEECCEEEEEECCEEEEEEEECCCEEEECEEEECCEEEEEECCCCCEEEEE
HQRQKIWHYCMIGMGAIVTKKLVIEPFSIYVGNPAKKIGTNDKGIEKSGIDERAMATIQE
EHHHHHHHHHHHHCHHHHHHHEEECEEEEEECCCHHHCCCCCCCCCCCCCCHHHHHHHHH
EFNARR
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA