Click here to switch to the map view.

The map label for this gene is nuoN [H]

Identifier: 93005415

GI number: 93005415

Start: 698593

End: 700071

Strand: Direct

Name: nuoN [H]

Synonym: Pcryo_0585

Alternate gene names: 93005415

Gene position: 698593-700071 (Clockwise)

Preceding gene: 93005414

Following gene: 93005416

Centisome position: 22.83

GC content: 44.35

Gene sequence:

>1479_bases
ATGAACGATTTTACGATGAATGATTTGATGGGGCTACTGCCTTATGCACCAATCATTGCGGTAGTTATTACAGTATTGGT
GGTGATGATTGCCATCACGATGAAGCGCTCACATATGGTGACCGGTACGATTTCGGTCATCGGTCTCAATATCGGTCTGT
TTATTTTGCTTGGGCAAATGGCAGGTATAATCGATAGTGGCACACTGGTGCCAGCGGCTGAGCAGTTATTTGTCATTGAT
AACTTCGCTCAGTTTAATATGGTGATTGTCTTTATCTGTGCATTGGCTTGTTGTACGTTGTCTTATGCGTATTTAGCAAA
CCTCAACGATAATAAAGAAGAGCTGTATTTGCTCATGTTGCTATCGACGATTGGTGCACTGCTTATGGTTTGCGCCCAGC
ATTTGGCATCATTCTTTATGAGCCTTGAGATGCTATCGATACCGCTATATGGCATGCTGTCCTATACCTATATGCGCACC
CGCTCGCTTGAGTCAGGGCTGAAATACTTAGTGCTATCAGCGACAGCATCGGCAACGCTGCTGATGGGTATGGCATTTAT
TTATGCAGAAGTCGGCTCACTGGCATTTAAGCCTATTAGTTTAACTTTGGCTGATACGTTTGAATCGCCGCTGTTAATCT
TAGGGGCAGCGATGATGATGTTTGGTATCGCCTTTAAACTCTCTGCTGCGCCCTTTCATATCTGGACACCAGATGTCTAT
GAAGGCGCCCCTGCACCTATCGCGACTTATCTGGCCTCGGTATCAAAAGTAGCGATGATGGCATTGGCAGTACGATTTTT
AATTGATACCTCACTATTGGCATTGCCATCGGTACAGATGCTGCTTATGGTCATGGCAACCTTGTCGATTTTGCTAGGTA
ACTTACTTGCGGTACGCCAAACAAGTCTCAAACGTTTACTTGGTTATTCATCGATTGCCCATATGGGTTATGTGTTAATC
GTAATCGTGAGCATTGGTTCTGCTGCTGATAGTATCTCTAGTATGTATATGGCGATTTATGCCTTTACCTCTATTGGTGC
CTTTGGTGTCGTGACCTTGATGTCTAGCCCTTATCGCTTATCTGGTGAAGCCGATCAATTGATTCATTATCAAGGATTGT
TCTGGAGACGTCCGGTATTGACTGGTGTCATGACTATCATGATGCTATCTCTAGCGGGCATTCCATTAACCGCAGGCTTT
ATTACTAAGCTGTTTGCGGTTCTTGCTGCAGTACAAGGTACCAACTGGTTCTTGGCAGCGATGATTATCCTCGGTAGTGC
GATTGGCTTGTTCTATTACTTGCGCGTCTTGCTCACACTATTTAAGCGTCCAAAACAATTTATTGAATTTGACGTCTCGA
AGCAGTGGGGTCTACGTACTGGTGGTATCATGGTCATAGCAGTCACGGCGATCATCTTGTTCTTTGGCGTATTACCAAAT
AGTATGATTGAATGGGCAAGTTTGGCTCGTATTTGGTAA

Upstream 100 bases:

>100_bases
AAGTCATGCGATGCAGTGGATTAATAACGCTTATATATATAGTCAAGTAACCCAAGTAGATGCCTCGCAGCTGCTTGATG
CAATGGAGGCACGTTAAGTC

Downstream 100 bases:

>100_bases
GCTTAAAAAATAGGTATACAAAGCTGAAATAAGTAATGCTATATCCATACTATTACTTATTCATTGTTACGGTTCGAAAA
ACAAGATGCGCCCGCTTTGT

Product: proton-translocating NADH-quinone oxidoreductase, chain N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MNDFTMNDLMGLLPYAPIIAVVITVLVVMIAITMKRSHMVTGTISVIGLNIGLFILLGQMAGIIDSGTLVPAAEQLFVID
NFAQFNMVIVFICALACCTLSYAYLANLNDNKEELYLLMLLSTIGALLMVCAQHLASFFMSLEMLSIPLYGMLSYTYMRT
RSLESGLKYLVLSATASATLLMGMAFIYAEVGSLAFKPISLTLADTFESPLLILGAAMMMFGIAFKLSAAPFHIWTPDVY
EGAPAPIATYLASVSKVAMMALAVRFLIDTSLLALPSVQMLLMVMATLSILLGNLLAVRQTSLKRLLGYSSIAHMGYVLI
VIVSIGSAADSISSMYMAIYAFTSIGAFGVVTLMSSPYRLSGEADQLIHYQGLFWRRPVLTGVMTIMMLSLAGIPLTAGF
ITKLFAVLAAVQGTNWFLAAMIILGSAIGLFYYLRVLLTLFKRPKQFIEFDVSKQWGLRTGGIMVIAVTAIILFFGVLPN
SMIEWASLARIW

Sequences:

>Translated_492_residues
MNDFTMNDLMGLLPYAPIIAVVITVLVVMIAITMKRSHMVTGTISVIGLNIGLFILLGQMAGIIDSGTLVPAAEQLFVID
NFAQFNMVIVFICALACCTLSYAYLANLNDNKEELYLLMLLSTIGALLMVCAQHLASFFMSLEMLSIPLYGMLSYTYMRT
RSLESGLKYLVLSATASATLLMGMAFIYAEVGSLAFKPISLTLADTFESPLLILGAAMMMFGIAFKLSAAPFHIWTPDVY
EGAPAPIATYLASVSKVAMMALAVRFLIDTSLLALPSVQMLLMVMATLSILLGNLLAVRQTSLKRLLGYSSIAHMGYVLI
VIVSIGSAADSISSMYMAIYAFTSIGAFGVVTLMSSPYRLSGEADQLIHYQGLFWRRPVLTGVMTIMMLSLAGIPLTAGF
ITKLFAVLAAVQGTNWFLAAMIILGSAIGLFYYLRVLLTLFKRPKQFIEFDVSKQWGLRTGGIMVIAVTAIILFFGVLPN
SMIEWASLARIW
>Mature_492_residues
MNDFTMNDLMGLLPYAPIIAVVITVLVVMIAITMKRSHMVTGTISVIGLNIGLFILLGQMAGIIDSGTLVPAAEQLFVID
NFAQFNMVIVFICALACCTLSYAYLANLNDNKEELYLLMLLSTIGALLMVCAQHLASFFMSLEMLSIPLYGMLSYTYMRT
RSLESGLKYLVLSATASATLLMGMAFIYAEVGSLAFKPISLTLADTFESPLLILGAAMMMFGIAFKLSAAPFHIWTPDVY
EGAPAPIATYLASVSKVAMMALAVRFLIDTSLLALPSVQMLLMVMATLSILLGNLLAVRQTSLKRLLGYSSIAHMGYVLI
VIVSIGSAADSISSMYMAIYAFTSIGAFGVVTLMSSPYRLSGEADQLIHYQGLFWRRPVLTGVMTIMMLSLAGIPLTAGF
ITKLFAVLAAVQGTNWFLAAMIILGSAIGLFYYLRVLLTLFKRPKQFIEFDVSKQWGLRTGGIMVIAVTAIILFFGVLPN
SMIEWASLARIW

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831108, Length=339, Percent_Identity=24.7787610619469, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI251831117, Length=377, Percent_Identity=23.8726790450928, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI145693160, Length=490, Percent_Identity=43.8775510204082, Blast_Score=408, Evalue=1e-115,
Organism=Escherichia coli, GI1788829, Length=361, Percent_Identity=29.0858725761773, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788831, Length=172, Percent_Identity=26.7441860465116, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788614, Length=326, Percent_Identity=23.0061349693252, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 53509; Mature: 53509

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
6.9 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
6.9 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDFTMNDLMGLLPYAPIIAVVITVLVVMIAITMKRSHMVTGTISVIGLNIGLFILLGQM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHH
AGIIDSGTLVPAAEQLFVIDNFAQFNMVIVFICALACCTLSYAYLANLNDNKEELYLLML
HHHHCCCCCCCCCHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LSTIGALLMVCAQHLASFFMSLEMLSIPLYGMLSYTYMRTRSLESGLKYLVLSATASATL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHEEEHHHHHHHHH
LMGMAFIYAEVGSLAFKPISLTLADTFESPLLILGAAMMMFGIAFKLSAAPFHIWTPDVY
HHHHHHHHHHHHHHHCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
EGAPAPIATYLASVSKVAMMALAVRFLIDTSLLALPSVQMLLMVMATLSILLGNLLAVRQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSLKRLLGYSSIAHMGYVLIVIVSIGSAADSISSMYMAIYAFTSIGAFGVVTLMSSPYRL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SGEADQLIHYQGLFWRRPVLTGVMTIMMLSLAGIPLTAGFITKLFAVLAAVQGTNWFLAA
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
MIILGSAIGLFYYLRVLLTLFKRPKQFIEFDVSKQWGLRTGGIMVIAVTAIILFFGVLPN
HHHHHHHHHHHHHHHHHHHHHHCCHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCH
SMIEWASLARIW
HHHHHHHHHHCC
>Mature Secondary Structure
MNDFTMNDLMGLLPYAPIIAVVITVLVVMIAITMKRSHMVTGTISVIGLNIGLFILLGQM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHH
AGIIDSGTLVPAAEQLFVIDNFAQFNMVIVFICALACCTLSYAYLANLNDNKEELYLLML
HHHHCCCCCCCCCHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LSTIGALLMVCAQHLASFFMSLEMLSIPLYGMLSYTYMRTRSLESGLKYLVLSATASATL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHEEEHHHHHHHHH
LMGMAFIYAEVGSLAFKPISLTLADTFESPLLILGAAMMMFGIAFKLSAAPFHIWTPDVY
HHHHHHHHHHHHHHHCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
EGAPAPIATYLASVSKVAMMALAVRFLIDTSLLALPSVQMLLMVMATLSILLGNLLAVRQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSLKRLLGYSSIAHMGYVLIVIVSIGSAADSISSMYMAIYAFTSIGAFGVVTLMSSPYRL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SGEADQLIHYQGLFWRRPVLTGVMTIMMLSLAGIPLTAGFITKLFAVLAAVQGTNWFLAA
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
MIILGSAIGLFYYLRVLLTLFKRPKQFIEFDVSKQWGLRTGGIMVIAVTAIILFFGVLPN
HHHHHHHHHHHHHHHHHHHHHHCCHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCH
SMIEWASLARIW
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA