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The map label for this gene is yhcX [H]

Identifier: 93005237

GI number: 93005237

Start: 494217

End: 495854

Strand: Reverse

Name: yhcX [H]

Synonym: Pcryo_0407

Alternate gene names: 93005237

Gene position: 495854-494217 (Counterclockwise)

Preceding gene: 93005239

Following gene: 93005236

Centisome position: 16.21

GC content: 44.14

Gene sequence:

>1638_bases
ATGAGTAAGATAGAAAAACCAGAAGACTTTCATTTAACGATTGCTGAGATTAAGAAAAAAGACTACCCGCAACTTAAAGC
GTTAATGGATCGAGTCTATGTCAATTTAGGCGGTGCATGGTCAAAGAATACAATTCATACTTTGATTGACGCTTTCCCAG
AAGGGCAGATTGCTTTATTTGATCACGACGAGCTGATTGGTATCGTATTATCTATGCGCGTTGATTATGCAAAGTTCTCT
AATCCACATACCTATGATGACTTGATTGGTCATAAAGAGATTATCAGAGACAACCCTGAAGGCGATGCTATCTATGGTTT
AGACGCTCTCATTGACCCTGAATATCGTGGTTATCGCTTGGGTCGCAGGCTGTATGATGCCCGTAAAGAGCTTTGTCGTC
AGTTGAACTTCCGAGCTATTTTAGCTGGTGGTCGTATTCCAAACTACCACAACCATCAAGATTTAACGCCCGGTGACTAT
ATCGATGCGGTTGCCTCACGCGAAATTCATGATTCTGCGCTTTCTTTCCAGTTATCGAATGGTTTTATCGTCAAGCGTAT
TTTGACCGCTTATTTGCCAGATGACAAACAGTCTAAAGGCTTTGCGACCTTACTTGAGTGGGCAAATATTTATTATGAGC
CAAAAGACTATAAGCCCAATACGCGCAAATCTGAAGTGCGTATCGGCGGTATCCAGTGGCAGATGCGTGAAGTTGAGTCG
CCAGAAGAGCTGTTGCAGCAAGTTGAATTCTTTGTCGACGTTATGGCTGATTACAACTCAGACTTTGCCTGCTTGCCAGA
ATTTTTTAACGCGCCATTGATGGGTTTGTGTGAGTCGACGGATCAAAACATTGCGATTCGCTTTTTGGCAGGTTATACCG
AGTGGTTTAAAAACGAAATATCGCATTTAGCGGTCAGCTATAACGTTAACGTTATTATGGGCTCCATGCCATTACTAGAT
GAAGACGACACGCTGTACAATGTCAGCTATCTGTGTCGCCGCGACGGTACGGTAGAAGAGCAACGCAAAATCCATATTAC
CCCTCATGAGCGTAGCGCTTGGGTCATCGAAGGCGGTGATGAGGTCAAAGTATTTGATACGGATGCTGGTCGTATTGGTA
TCTTGGTCTGTTATGATGTTGAATTCCCTGAGCTTGCCCGCTTGTTGGCGCTCGACGATATGGATATTTTGTTCGTGCCT
TTTTGGACAGATACCAAAAACGGCTACTTACGTGTGCGCCACTGTGCTCAAGCGCGAGCCATTGAAAACGAATGTTATGT
GATGATTTGTGGATCAGTGGGTAACTTACCGCAAGTTGAGAGCTTAGACATTCAGTACGCGCAGTCGTCTATTTTTTCAC
CGTCAGATTTTGCATTCCCGCATGACGCGATTATGGCAGAAACGACGGCCAACACTGAGATGGTTTTCTTTTCAGATGTG
AATTTAGACAAGCTCACTCACGTCCGTAACGAAGGTTCGGTCCACAATTTGCTTGATCGCCGTGATGACTTATTTAGCTT
AAAATGGAAGCGAAAATCCAAAATTCCAGCGAGCAAGTTGAGTGATGAAGAGCGCCGTGAAAACTCTGGTAGCGTACTTT
TAGGCGATCCATTACAAAACCGTGCGCAAAAGCCTTAA

Upstream 100 bases:

>100_bases
TATCCCACTTATATAAAAATTAATCGCAAGATGTGTCGTACCTTCATTTATCAATATCACTTATTAACACCCGCATACAG
AAACAACAGACAGGAATTTT

Downstream 100 bases:

>100_bases
GTGAGGACTATCCAACCGTTAATTAATAGCATACTTAATTAATGAGACTCTTAATATTTTAATCATACGGCTGACTATTC
AGCCGTATATTTTTATCTAT

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 544

Protein sequence:

>545_residues
MSKIEKPEDFHLTIAEIKKKDYPQLKALMDRVYVNLGGAWSKNTIHTLIDAFPEGQIALFDHDELIGIVLSMRVDYAKFS
NPHTYDDLIGHKEIIRDNPEGDAIYGLDALIDPEYRGYRLGRRLYDARKELCRQLNFRAILAGGRIPNYHNHQDLTPGDY
IDAVASREIHDSALSFQLSNGFIVKRILTAYLPDDKQSKGFATLLEWANIYYEPKDYKPNTRKSEVRIGGIQWQMREVES
PEELLQQVEFFVDVMADYNSDFACLPEFFNAPLMGLCESTDQNIAIRFLAGYTEWFKNEISHLAVSYNVNVIMGSMPLLD
EDDTLYNVSYLCRRDGTVEEQRKIHITPHERSAWVIEGGDEVKVFDTDAGRIGILVCYDVEFPELARLLALDDMDILFVP
FWTDTKNGYLRVRHCAQARAIENECYVMICGSVGNLPQVESLDIQYAQSSIFSPSDFAFPHDAIMAETTANTEMVFFSDV
NLDKLTHVRNEGSVHNLLDRRDDLFSLKWKRKSKIPASKLSDEERRENSGSVLLGDPLQNRAQKP

Sequences:

>Translated_545_residues
MSKIEKPEDFHLTIAEIKKKDYPQLKALMDRVYVNLGGAWSKNTIHTLIDAFPEGQIALFDHDELIGIVLSMRVDYAKFS
NPHTYDDLIGHKEIIRDNPEGDAIYGLDALIDPEYRGYRLGRRLYDARKELCRQLNFRAILAGGRIPNYHNHQDLTPGDY
IDAVASREIHDSALSFQLSNGFIVKRILTAYLPDDKQSKGFATLLEWANIYYEPKDYKPNTRKSEVRIGGIQWQMREVES
PEELLQQVEFFVDVMADYNSDFACLPEFFNAPLMGLCESTDQNIAIRFLAGYTEWFKNEISHLAVSYNVNVIMGSMPLLD
EDDTLYNVSYLCRRDGTVEEQRKIHITPHERSAWVIEGGDEVKVFDTDAGRIGILVCYDVEFPELARLLALDDMDILFVP
FWTDTKNGYLRVRHCAQARAIENECYVMICGSVGNLPQVESLDIQYAQSSIFSPSDFAFPHDAIMAETTANTEMVFFSDV
NLDKLTHVRNEGSVHNLLDRRDDLFSLKWKRKSKIPASKLSDEERRENSGSVLLGDPLQNRAQKP
>Mature_544_residues
SKIEKPEDFHLTIAEIKKKDYPQLKALMDRVYVNLGGAWSKNTIHTLIDAFPEGQIALFDHDELIGIVLSMRVDYAKFSN
PHTYDDLIGHKEIIRDNPEGDAIYGLDALIDPEYRGYRLGRRLYDARKELCRQLNFRAILAGGRIPNYHNHQDLTPGDYI
DAVASREIHDSALSFQLSNGFIVKRILTAYLPDDKQSKGFATLLEWANIYYEPKDYKPNTRKSEVRIGGIQWQMREVESP
EELLQQVEFFVDVMADYNSDFACLPEFFNAPLMGLCESTDQNIAIRFLAGYTEWFKNEISHLAVSYNVNVIMGSMPLLDE
DDTLYNVSYLCRRDGTVEEQRKIHITPHERSAWVIEGGDEVKVFDTDAGRIGILVCYDVEFPELARLLALDDMDILFVPF
WTDTKNGYLRVRHCAQARAIENECYVMICGSVGNLPQVESLDIQYAQSSIFSPSDFAFPHDAIMAETTANTEMVFFSDVN
LDKLTHVRNEGSVHNLLDRRDDLFSLKWKRKSKIPASKLSDEERRENSGSVLLGDPLQNRAQKP

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=300, Percent_Identity=24, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17556280, Length=292, Percent_Identity=25.3424657534247, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323383, Length=260, Percent_Identity=28.4615384615385, Blast_Score=90, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6322335, Length=240, Percent_Identity=23.3333333333333, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355835, Length=261, Percent_Identity=22.9885057471264, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 62395; Mature: 62264

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00527 RIBOSOMAL_S14 ; PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIEKPEDFHLTIAEIKKKDYPQLKALMDRVYVNLGGAWSKNTIHTLIDAFPEGQIALF
CCCCCCCCCCEEEHHHHCCCCCHHHHHHHHHHHEECCCCCCCCHHHHHHHHCCCCCEEEE
DHDELIGIVLSMRVDYAKFSNPHTYDDLIGHKEIIRDNPEGDAIYGLDALIDPEYRGYRL
ECHHHHHHHHHHHCCHHHCCCCCCHHHHHCCHHHHCCCCCCCEEEEEHHEECCCCCCHHH
GRRLYDARKELCRQLNFRAILAGGRIPNYHNHQDLTPGDYIDAVASREIHDSALSFQLSN
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHCHHHCCCEEEEECC
GFIVKRILTAYLPDDKQSKGFATLLEWANIYYEPKDYKPNTRKSEVRIGGIQWQMREVES
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHEECCCCCCCCCCCCEEEEECEEEEEHHCCC
PEELLQQVEFFVDVMADYNSDFACLPEFFNAPLMGLCESTDQNIAIRFLAGYTEWFKNEI
HHHHHHHHHHHHHHHHHCCCCCEECHHHHCCCHHHHHCCCCCCEEEEEEHHHHHHHHHHH
SHLAVSYNVNVIMGSMPLLDEDDTLYNVSYLCRRDGTVEEQRKIHITPHERSAWVIEGGD
HHEEEEEEEEEEECCCCCCCCCCCEEEEEHHCCCCCCCCCCCEEEECCCCCCEEEEECCC
EVKVFDTDAGRIGILVCYDVEFPELARLLALDDMDILFVPFWTDTKNGYLRVRHCAQARA
EEEEEECCCCCEEEEEEEECCHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEHHHHHH
IENECYVMICGSVGNLPQVESLDIQYAQSSIFSPSDFAFPHDAIMAETTANTEMVFFSDV
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHEEECCCCCEEEEEECC
NLDKLTHVRNEGSVHNLLDRRDDLFSLKWKRKSKIPASKLSDEERRENSGSVLLGDPLQN
CHHHHHHHCCCCCHHHHHHCCCCEEEEEECCCCCCCHHHCCCHHHHCCCCCEEECCCHHH
RAQKP
CCCCC
>Mature Secondary Structure 
SKIEKPEDFHLTIAEIKKKDYPQLKALMDRVYVNLGGAWSKNTIHTLIDAFPEGQIALF
CCCCCCCCCEEEHHHHCCCCCHHHHHHHHHHHEECCCCCCCCHHHHHHHHCCCCCEEEE
DHDELIGIVLSMRVDYAKFSNPHTYDDLIGHKEIIRDNPEGDAIYGLDALIDPEYRGYRL
ECHHHHHHHHHHHCCHHHCCCCCCHHHHHCCHHHHCCCCCCCEEEEEHHEECCCCCCHHH
GRRLYDARKELCRQLNFRAILAGGRIPNYHNHQDLTPGDYIDAVASREIHDSALSFQLSN
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHCHHHCCCEEEEECC
GFIVKRILTAYLPDDKQSKGFATLLEWANIYYEPKDYKPNTRKSEVRIGGIQWQMREVES
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHEECCCCCCCCCCCCEEEEECEEEEEHHCCC
PEELLQQVEFFVDVMADYNSDFACLPEFFNAPLMGLCESTDQNIAIRFLAGYTEWFKNEI
HHHHHHHHHHHHHHHHHCCCCCEECHHHHCCCHHHHHCCCCCCEEEEEEHHHHHHHHHHH
SHLAVSYNVNVIMGSMPLLDEDDTLYNVSYLCRRDGTVEEQRKIHITPHERSAWVIEGGD
HHEEEEEEEEEEECCCCCCCCCCCEEEEEHHCCCCCCCCCCCEEEECCCCCCEEEEECCC
EVKVFDTDAGRIGILVCYDVEFPELARLLALDDMDILFVPFWTDTKNGYLRVRHCAQARA
EEEEEECCCCCEEEEEEEECCHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEHHHHHH
IENECYVMICGSVGNLPQVESLDIQYAQSSIFSPSDFAFPHDAIMAETTANTEMVFFSDV
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHEEECCCCCEEEEEECC
NLDKLTHVRNEGSVHNLLDRRDDLFSLKWKRKSKIPASKLSDEERRENSGSVLLGDPLQN
CHHHHHHHCCCCCHHHHHHCCCCEEEEEECCCCCCCHHHCCCHHHHCCCCCEEECCCHHH
RAQKP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]