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The map label for this gene is pilE1 [H]

Identifier: 93005100

GI number: 93005100

Start: 319728

End: 320183

Strand: Direct

Name: pilE1 [H]

Synonym: Pcryo_0269

Alternate gene names: 93005100

Gene position: 319728-320183 (Clockwise)

Preceding gene: 93005099

Following gene: 93005101

Centisome position: 10.45

GC content: 42.11

Gene sequence:

>456_bases
ATGAACACTGCACAAAAAGGTTTTACCTTAATCGAACTAATGATCGTAATCGCCATTATCGGTATCTTGGCTGCGATCGC
TATCCCTGCTTATCAGGACTATATTGCTCGTTCACAAGTAGCTGAAGCTTTTGCTCTTACTGCTGGACAAAAAACTGCTA
TTGCAGAATATGCGCAAACTAATGGTGTTTATCCGGGTACAGCTACAGCGCCGACAAATGGTTCTTTGACAGCTGCTGGA
ACTTACGCTGATGCTACAGTAGCAGCGGGTACTGGTGTTATTACTGTGACTATGAAACCGGCTGGTACTGTAAATGCTAA
TATCGCTGGTAAAACAATTACTTTAACGCCACCTGCACTTACAGGCTCTAATACTACTTTCAACTTTAGCTGTACTACAA
CTGGTGGTACTAAGATGGATCAAAAATACCTACCTAAGTCTTGTGTAGCTAGCTAA

Upstream 100 bases:

>100_bases
GCTAAATGCAGCATCTATAATAAGAGAAAAACATATTATATCCCTAAAGATAAAAAGCGCTATTAGCCAATTATCTTTAT
ATACCCCCTAAGGAGTTCAT

Downstream 100 bases:

>100_bases
TAATTAATGCTTAACTTTTTTCAAATAAATAAAAATAAAGAGCTATTAATAGCTCTTTATTTTTTGCCTTTTTTTTTAGG
TTGGAGTGTAGGGTTTAATA

Product: fimbrial protein pilin

Products: NA

Alternate protein names: MS11 antigen; Pilin [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MNTAQKGFTLIELMIVIAIIGILAAIAIPAYQDYIARSQVAEAFALTAGQKTAIAEYAQTNGVYPGTATAPTNGSLTAAG
TYADATVAAGTGVITVTMKPAGTVNANIAGKTITLTPPALTGSNTTFNFSCTTTGGTKMDQKYLPKSCVAS

Sequences:

>Translated_151_residues
MNTAQKGFTLIELMIVIAIIGILAAIAIPAYQDYIARSQVAEAFALTAGQKTAIAEYAQTNGVYPGTATAPTNGSLTAAG
TYADATVAAGTGVITVTMKPAGTVNANIAGKTITLTPPALTGSNTTFNFSCTTTGGTKMDQKYLPKSCVAS
>Mature_151_residues
MNTAQKGFTLIELMIVIAIIGILAAIAIPAYQDYIARSQVAEAFALTAGQKTAIAEYAQTNGVYPGTATAPTNGSLTAAG
TYADATVAAGTGVITVTMKPAGTVNANIAGKTITLTPPALTGSNTTFNFSCTTTGGTKMDQKYLPKSCVAS

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 15288; Mature: 15288

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTAQKGFTLIELMIVIAIIGILAAIAIPAYQDYIARSQVAEAFALTAGQKTAIAEYAQT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
NGVYPGTATAPTNGSLTAAGTYADATVAAGTGVITVTMKPAGTVNANIAGKTITLTPPAL
CCCCCCCCCCCCCCCEEECCCCCCCEEECCCCEEEEEECCCCCEECCCCCCEEEECCCCC
TGSNTTFNFSCTTTGGTKMDQKYLPKSCVAS
CCCCCEEEEEEECCCCCCCCHHHCCHHHCCC
>Mature Secondary Structure
MNTAQKGFTLIELMIVIAIIGILAAIAIPAYQDYIARSQVAEAFALTAGQKTAIAEYAQT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
NGVYPGTATAPTNGSLTAAGTYADATVAAGTGVITVTMKPAGTVNANIAGKTITLTPPAL
CCCCCCCCCCCCCCCEEECCCCCCCEEECCCCEEEEEECCCCCEECCCCCCEEEECCCCC
TGSNTTFNFSCTTTGGTKMDQKYLPKSCVAS
CCCCCEEEEEEECCCCCCCCHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6148752; 2872674; 1671354; 1348857; 6143785; 7477282; 10048019 [H]