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The map label for this gene is dsbD [H]

Identifier: 93005089

GI number: 93005089

Start: 305479

End: 306039

Strand: Direct

Name: dsbD [H]

Synonym: Pcryo_0258

Alternate gene names: 93005089

Gene position: 305479-306039 (Clockwise)

Preceding gene: 93005088

Following gene: 93005090

Centisome position: 9.98

GC content: 41.35

Gene sequence:

>561_bases
ATGTCTATCGAAACATCAAAATCGAAATCAATTATCATGAATAAACAATTAACTAAAAAGCCTTATTTGCTTGCTATAAC
AGCCACTGCTTTGATGACTACTTTGTCAATGACGTCTGTTGCGACTCAAGCTGCAGGTCTGGGGGAATTGTTTAGTAATA
ATAGTGCTCAGCAATCAAAATTTTTGCCCGTTGATAAGGCATTTCAAGTGACTAGCAGTACCAAGGCGACCACTAAAGGC
ACGCAGTTATCGATCGCTTTTGATATCACACCAGGTCATTACGTTTATAAAGATAAGCTGACCTTGAGTTTTCCAAAAGG
TATCAATGCGTCGCCATTTACCTTTAGCCAATCGCCTGTCTCTATTGATGATCCAACCTTTGGCAAGGTACCCGTATTTA
CGCAAAAAACTGTGATAGCAACGACTATGATGACGACCAAAAACGGTAAAGCGGCAAAGAATGTGCCGGTTGTGATTGGC
TGGCAAGGTTGTGCTCAAGCTGGACTATGCTATCCGCCAGAAAAGGTCAAAACCACGTTAAACATTGCAGTCAAACGTTA
G

Upstream 100 bases:

>100_bases
TAAACGGAATCTTAACCCTGCTATTTATTATTAAAACGAGTGACTATTTTCTATTGATTGTAAAAAAACAGCTGTTCTTC
TAGTAATCTGAGGTAATCAT

Downstream 100 bases:

>100_bases
TCACTAATATATAGCACAAGTAGGTTGATTTATATAGTCGTTATAACAGGTAGTCCTTTATGTCCATCAAGACAGTAAAA
AGCATTTCGTCATTTAAAGC

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSIETSKSKSIIMNKQLTKKPYLLAITATALMTTLSMTSVATQAAGLGELFSNNSAQQSKFLPVDKAFQVTSSTKATTKG
TQLSIAFDITPGHYVYKDKLTLSFPKGINASPFTFSQSPVSIDDPTFGKVPVFTQKTVIATTMMTTKNGKAAKNVPVVIG
WQGCAQAGLCYPPEKVKTTLNIAVKR

Sequences:

>Translated_186_residues
MSIETSKSKSIIMNKQLTKKPYLLAITATALMTTLSMTSVATQAAGLGELFSNNSAQQSKFLPVDKAFQVTSSTKATTKG
TQLSIAFDITPGHYVYKDKLTLSFPKGINASPFTFSQSPVSIDDPTFGKVPVFTQKTVIATTMMTTKNGKAAKNVPVVIG
WQGCAQAGLCYPPEKVKTTLNIAVKR
>Mature_185_residues
SIETSKSKSIIMNKQLTKKPYLLAITATALMTTLSMTSVATQAAGLGELFSNNSAQQSKFLPVDKAFQVTSSTKATTKGT
QLSIAFDITPGHYVYKDKLTLSFPKGINASPFTFSQSPVSIDDPTFGKVPVFTQKTVIATTMMTTKNGKAAKNVPVVIGW
QGCAQAGLCYPPEKVKTTLNIAVKR

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 19934; Mature: 19803

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIETSKSKSIIMNKQLTKKPYLLAITATALMTTLSMTSVATQAAGLGELFSNNSAQQSK
CCCCCCCCCEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
FLPVDKAFQVTSSTKATTKGTQLSIAFDITPGHYVYKDKLTLSFPKGINASPFTFSQSPV
CCCCCHHEEECCCCCCCCCCCEEEEEEECCCCCEEEEEEEEEECCCCCCCCCEEECCCCC
SIDDPTFGKVPVFTQKTVIATTMMTTKNGKAAKNVPVVIGWQGCAQAGLCYPPEKVKTTL
CCCCCCCCCCCEEECCEEEEEEEEEECCCCCCCCCCEEEECCHHCCCCCCCCHHHHEEEE
NIAVKR
EEEEEC
>Mature Secondary Structure 
SIETSKSKSIIMNKQLTKKPYLLAITATALMTTLSMTSVATQAAGLGELFSNNSAQQSK
CCCCCCCCEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
FLPVDKAFQVTSSTKATTKGTQLSIAFDITPGHYVYKDKLTLSFPKGINASPFTFSQSPV
CCCCCHHEEECCCCCCCCCCCEEEEEEECCCCCEEEEEEEEEECCCCCCCCCEEECCCCC
SIDDPTFGKVPVFTQKTVIATTMMTTKNGKAAKNVPVVIGWQGCAQAGLCYPPEKVKTTL
CCCCCCCCCCCEEECCEEEEEEEEEECCCCCCCCCCEEEECCHHCCCCCCCCHHHHEEEE
NIAVKR
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA