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The map label for this gene is dsbD [H]

Identifier: 93005090

GI number: 93005090

Start: 306099

End: 308330

Strand: Direct

Name: dsbD [H]

Synonym: Pcryo_0259

Alternate gene names: 93005090

Gene position: 306099-308330 (Clockwise)

Preceding gene: 93005089

Following gene: 93005091

Centisome position: 10.0

GC content: 43.41

Gene sequence:

>2232_bases
ATGTCCATCAAGACAGTAAAAAGCATTTCGTCATTTAAAGCGGTATCCACCAGAAATCAGTCTTCAAAAAATTTGCCATC
AGTTGTAAATAAAGTGCCAAAGAAGTCTTATTTACTGGCACTAACTATAGCGAGTAGCTCGTTATTTGTAGGATTGACTG
CGACGACTATGACGACGCAGGCAGCAGGATTGGGCGATCTTTTTAGTAGCAATCAAAGCGCTGGACAATCGAAATTTCTG
TCAGTGGATAAAGCCTTCCAAGTCACGAGTAACAGTAAAGCTGTTAAAGCTGGCACTCAGTTATCGATTAATTTTGATAT
CACTCCAGAGCATTATGTTTACAAGAATCAGCTTAAACTCACTTTGCCTGCTGGGGTTACAGCGGCACCGTTTACTTTTA
GTCAAACGCCTGTCTTAATTGATGATCCAACTTTTGGTAAAGTGCCAGTATTTGATCAAAAAAATATGGTAGCCACTACT
ACTCTGAGTACTAGTGGCAAGAGCATTGACAATGCAGCGGTGGTGATTGGTTGGCAAGGCTGCGCCAAAGCAGGACTTTG
CTACCCGCCTGAGAAAATAAAAACCAATGTCGATATCGTTGCAAGCGCGCCGCAAGCGGTGGTTAATACGATAAGTAATG
TCACTGGTGTTGCTAAAAGCGATGTCAATCAAGAGACTACTAATGCAAATTCGGTAAATAATAGCAATAGCGTCACAATA
TCAGAGGCGCCAAATGCCACAAGTATAGACAGTACTGAGGCAATGAGTCCTGAAGCAGAGCAAGCGCTTGCAGAAGAAGA
TGAAGTCATTGATTATGCGTTGTTGGATGATGAGGCTTTAGATGGAGAGCTTGGCGCCACCAATACGATTTCTGGCGCTG
ATACACCGTTAGCAGATAATGCTGCTCCGACAAATGATACGCTAGCTACCGCAGATAATTTGGCTGATGGCGATCCGTTT
GGCTTAGCCAAGCATCCTTGGTTGGCATTAGGGTTACTATTCTTGGCAGGGCTTGGCTTAGCGCTTACGCCGTGCGTACT
ACCTATGTTACCTATCGTCGCAAATATTGTCGCCCGTCAGCAAAATCCAACGGTTAAAAAAGGTGTCATTTTAACGACAA
GTTATGCGATTGGAGTGTCGATTGCTTACGGGATACTTGGTGCTGTCATTGCTGTATTTGGTGAGTCACTCGGCATTATC
GGCTGGCTACAAAACCCAATCATCCTGATCAGTTTTGCAGTAATATTTGTTTTGTTGGCCCTTTACATGCTTGAAGTATT
TACCATTCGTTTGCCGCATTTTATCAGTAGTAAGATGCAGGGCTTAAGCCAAGCAGGCGATAGTAAGCTCGGTAGCGCTG
GTGGCAGTTTAGCTGCTGGATTTTTATCAGCATTGGTAGTATCACCTTGTGTTTCTGCACCATTATTTGGCGCTTTACTT
GCTGTCTCAACGATTGGTAATCCGCTATTGGGTTTTGCTGCCCTATTTATGCTAGGCTTTGGCTTGTCAGCGCCACTGAT
TTTGATTGGTGCTACCCAAGGCAAAATTATGCCAAAAGCGGGCGAGTGGATGAACTGGGTCAAGCAAGGTTTTGCCTTAT
TGTTATTTGCCGTAGCGTTACTATTAATAGAGCGCGTCTTTATATCGTCAGTAATGTTACTGGTATGGGCATTATGGTTT
ATGGTTGTGGCAACATGGGCATGGAGCTGGCGTGGTAAAGGTAGAATGCTATCGCAAGCCATCGGTTTGATAGCTGGTAT
TTGGGCTGCTACTTTAGTGATTGGCGCCGCACTTGGTAATGATGATAGCTTACATCCGTTAGCTTCATTAAGTGCCACCC
CTATGTTAGTACAGTCAGCTAACGGTCAAGCTGGCGCTCAAAATAATGCGACGAATAACTCAGATGAGCATATCACTACG
TTGGCAGAATTAGATGTTATCACTGCTGCCAATCCTAAAGTTTTGGTCGATTTAACCGCTGATTGGTGTATTGAATGTCG
CATTATGGATAAGAATTTATTTACCAATCGTCCCGCACAAATGCAAGACTGGGAATTGGTACGACTCGATATTACGGAAA
CCACAGCGGATTCTAAGGCAATTTTAGCGCGTTATAAATTATTTGGACCACCAACTTTATTGTATTACCAAGATGGTCAA
TTGGTACAAAAACAAGTGGGTGAGATTGGTCGTGCAGAGTTTGAGCAGACTTTGACGGCATTAAATAAATAA

Upstream 100 bases:

>100_bases
AAAAGGTCAAAACCACGTTAAACATTGCAGTCAAACGTTAGTCACTAATATATAGCACAAGTAGGTTGATTTATATAGTC
GTTATAACAGGTAGTCCTTT

Downstream 100 bases:

>100_bases
TAGTCGTATCGGAAATATTTTTTTATCCTCTTAAATGCCTTAATATAATTCCTATAAAAAAGCCAACGTACTGTCATAGT
ATGTTGGCTCTTTTATTTTT

Product: cytochrome c biogenesis protein, transmembrane region

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 743; Mature: 742

Protein sequence:

>743_residues
MSIKTVKSISSFKAVSTRNQSSKNLPSVVNKVPKKSYLLALTIASSSLFVGLTATTMTTQAAGLGDLFSSNQSAGQSKFL
SVDKAFQVTSNSKAVKAGTQLSINFDITPEHYVYKNQLKLTLPAGVTAAPFTFSQTPVLIDDPTFGKVPVFDQKNMVATT
TLSTSGKSIDNAAVVIGWQGCAKAGLCYPPEKIKTNVDIVASAPQAVVNTISNVTGVAKSDVNQETTNANSVNNSNSVTI
SEAPNATSIDSTEAMSPEAEQALAEEDEVIDYALLDDEALDGELGATNTISGADTPLADNAAPTNDTLATADNLADGDPF
GLAKHPWLALGLLFLAGLGLALTPCVLPMLPIVANIVARQQNPTVKKGVILTTSYAIGVSIAYGILGAVIAVFGESLGII
GWLQNPIILISFAVIFVLLALYMLEVFTIRLPHFISSKMQGLSQAGDSKLGSAGGSLAAGFLSALVVSPCVSAPLFGALL
AVSTIGNPLLGFAALFMLGFGLSAPLILIGATQGKIMPKAGEWMNWVKQGFALLLFAVALLLIERVFISSVMLLVWALWF
MVVATWAWSWRGKGRMLSQAIGLIAGIWAATLVIGAALGNDDSLHPLASLSATPMLVQSANGQAGAQNNATNNSDEHITT
LAELDVITAANPKVLVDLTADWCIECRIMDKNLFTNRPAQMQDWELVRLDITETTADSKAILARYKLFGPPTLLYYQDGQ
LVQKQVGEIGRAEFEQTLTALNK

Sequences:

>Translated_743_residues
MSIKTVKSISSFKAVSTRNQSSKNLPSVVNKVPKKSYLLALTIASSSLFVGLTATTMTTQAAGLGDLFSSNQSAGQSKFL
SVDKAFQVTSNSKAVKAGTQLSINFDITPEHYVYKNQLKLTLPAGVTAAPFTFSQTPVLIDDPTFGKVPVFDQKNMVATT
TLSTSGKSIDNAAVVIGWQGCAKAGLCYPPEKIKTNVDIVASAPQAVVNTISNVTGVAKSDVNQETTNANSVNNSNSVTI
SEAPNATSIDSTEAMSPEAEQALAEEDEVIDYALLDDEALDGELGATNTISGADTPLADNAAPTNDTLATADNLADGDPF
GLAKHPWLALGLLFLAGLGLALTPCVLPMLPIVANIVARQQNPTVKKGVILTTSYAIGVSIAYGILGAVIAVFGESLGII
GWLQNPIILISFAVIFVLLALYMLEVFTIRLPHFISSKMQGLSQAGDSKLGSAGGSLAAGFLSALVVSPCVSAPLFGALL
AVSTIGNPLLGFAALFMLGFGLSAPLILIGATQGKIMPKAGEWMNWVKQGFALLLFAVALLLIERVFISSVMLLVWALWF
MVVATWAWSWRGKGRMLSQAIGLIAGIWAATLVIGAALGNDDSLHPLASLSATPMLVQSANGQAGAQNNATNNSDEHITT
LAELDVITAANPKVLVDLTADWCIECRIMDKNLFTNRPAQMQDWELVRLDITETTADSKAILARYKLFGPPTLLYYQDGQ
LVQKQVGEIGRAEFEQTLTALNK
>Mature_742_residues
SIKTVKSISSFKAVSTRNQSSKNLPSVVNKVPKKSYLLALTIASSSLFVGLTATTMTTQAAGLGDLFSSNQSAGQSKFLS
VDKAFQVTSNSKAVKAGTQLSINFDITPEHYVYKNQLKLTLPAGVTAAPFTFSQTPVLIDDPTFGKVPVFDQKNMVATTT
LSTSGKSIDNAAVVIGWQGCAKAGLCYPPEKIKTNVDIVASAPQAVVNTISNVTGVAKSDVNQETTNANSVNNSNSVTIS
EAPNATSIDSTEAMSPEAEQALAEEDEVIDYALLDDEALDGELGATNTISGADTPLADNAAPTNDTLATADNLADGDPFG
LAKHPWLALGLLFLAGLGLALTPCVLPMLPIVANIVARQQNPTVKKGVILTTSYAIGVSIAYGILGAVIAVFGESLGIIG
WLQNPIILISFAVIFVLLALYMLEVFTIRLPHFISSKMQGLSQAGDSKLGSAGGSLAAGFLSALVVSPCVSAPLFGALLA
VSTIGNPLLGFAALFMLGFGLSAPLILIGATQGKIMPKAGEWMNWVKQGFALLLFAVALLLIERVFISSVMLLVWALWFM
VVATWAWSWRGKGRMLSQAIGLIAGIWAATLVIGAALGNDDSLHPLASLSATPMLVQSANGQAGAQNNATNNSDEHITTL
AELDVITAANPKVLVDLTADWCIECRIMDKNLFTNRPAQMQDWELVRLDITETTADSKAILARYKLFGPPTLLYYQDGQL
VQKQVGEIGRAEFEQTLTALNK

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=436, Percent_Identity=31.8807339449541, Blast_Score=182, Evalue=8e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 78390; Mature: 78259

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKTVKSISSFKAVSTRNQSSKNLPSVVNKVPKKSYLLALTIASSSLFVGLTATTMTTQ
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEEEEEEECCCEEEEEEEHHHHHH
AAGLGDLFSSNQSAGQSKFLSVDKAFQVTSNSKAVKAGTQLSINFDITPEHYVYKNQLKL
HCCCHHHHCCCCCCCCHHHEEHHHHEEECCCCCEEECCCEEEEEEECCCCCEEEECEEEE
TLPAGVTAAPFTFSQTPVLIDDPTFGKVPVFDQKNMVATTTLSTSGKSIDNAAVVIGWQG
EECCCCEECCCEECCCCEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCH
CAKAGLCYPPEKIKTNVDIVASAPQAVVNTISNVTGVAKSDVNQETTNANSVNNSNSVTI
HHCCCCCCCHHHHCCCCEEEECCHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCEEE
SEAPNATSIDSTEAMSPEAEQALAEEDEVIDYALLDDEALDGELGATNTISGADTPLADN
ECCCCCCCCCCCCCCCCHHHHHHHCCHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
AAPTNDTLATADNLADGDPFGLAKHPWLALGLLFLAGLGLALTPCVLPMLPIVANIVARQ
CCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QNPTVKKGVILTTSYAIGVSIAYGILGAVIAVFGESLGIIGWLQNPIILISFAVIFVLLA
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHH
LYMLEVFTIRLPHFISSKMQGLSQAGDSKLGSAGGSLAAGFLSALVVSPCVSAPLFGALL
HHHHHHHHHHCCHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AVSTIGNPLLGFAALFMLGFGLSAPLILIGATQGKIMPKAGEWMNWVKQGFALLLFAVAL
HHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LLIERVFISSVMLLVWALWFMVVATWAWSWRGKGRMLSQAIGLIAGIWAATLVIGAALGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
DDSLHPLASLSATPMLVQSANGQAGAQNNATNNSDEHITTLAELDVITAANPKVLVDLTA
CCCCCHHHHCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCCEEEEEECC
DWCIECRIMDKNLFTNRPAQMQDWELVRLDITETTADSKAILARYKLFGPPTLLYYQDGQ
CEEEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCH
LVQKQVGEIGRAEFEQTLTALNK
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIKTVKSISSFKAVSTRNQSSKNLPSVVNKVPKKSYLLALTIASSSLFVGLTATTMTTQ
CCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEEEEEEECCCEEEEEEEHHHHHH
AAGLGDLFSSNQSAGQSKFLSVDKAFQVTSNSKAVKAGTQLSINFDITPEHYVYKNQLKL
HCCCHHHHCCCCCCCCHHHEEHHHHEEECCCCCEEECCCEEEEEEECCCCCEEEECEEEE
TLPAGVTAAPFTFSQTPVLIDDPTFGKVPVFDQKNMVATTTLSTSGKSIDNAAVVIGWQG
EECCCCEECCCEECCCCEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCH
CAKAGLCYPPEKIKTNVDIVASAPQAVVNTISNVTGVAKSDVNQETTNANSVNNSNSVTI
HHCCCCCCCHHHHCCCCEEEECCHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCEEE
SEAPNATSIDSTEAMSPEAEQALAEEDEVIDYALLDDEALDGELGATNTISGADTPLADN
ECCCCCCCCCCCCCCCCHHHHHHHCCHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
AAPTNDTLATADNLADGDPFGLAKHPWLALGLLFLAGLGLALTPCVLPMLPIVANIVARQ
CCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QNPTVKKGVILTTSYAIGVSIAYGILGAVIAVFGESLGIIGWLQNPIILISFAVIFVLLA
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHH
LYMLEVFTIRLPHFISSKMQGLSQAGDSKLGSAGGSLAAGFLSALVVSPCVSAPLFGALL
HHHHHHHHHHCCHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AVSTIGNPLLGFAALFMLGFGLSAPLILIGATQGKIMPKAGEWMNWVKQGFALLLFAVAL
HHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LLIERVFISSVMLLVWALWFMVVATWAWSWRGKGRMLSQAIGLIAGIWAATLVIGAALGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
DDSLHPLASLSATPMLVQSANGQAGAQNNATNNSDEHITTLAELDVITAANPKVLVDLTA
CCCCCHHHHCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCCEEEEEECC
DWCIECRIMDKNLFTNRPAQMQDWELVRLDITETTADSKAILARYKLFGPPTLLYYQDGQ
CEEEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCH
LVQKQVGEIGRAEFEQTLTALNK
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA