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The map label for this gene is xcpR [H]

Identifier: 93005080

GI number: 93005080

Start: 293243

End: 294811

Strand: Direct

Name: xcpR [H]

Synonym: Pcryo_0249

Alternate gene names: 93005080

Gene position: 293243-294811 (Clockwise)

Preceding gene: 93005077

Following gene: 93005083

Centisome position: 9.58

GC content: 46.34

Gene sequence:

>1569_bases
ATGATGCAACTGCCGTACAGTTTTGCAAAACGCCATCAGATTTTGGTTATTCTAGCCATTGATCCTGAGCTGCCACCGAC
ATTGCTATTGACCAAGGTGACGCCGCTTTCAGCAATCAATGAAGCGGTGCGATTTTTACAGCAGCAAGGCATACGCGGTG
TGCCAATATATGAAAGTGTCAGCTCGGACGATTTTGAGAAACGCATGAATGCCGCTTATGCAGGTAATACTGGCGAGTCA
CAGCATATCGCCGCTGGCCTTGAAGACCATCCTGATCTTGATAGCTTGGCAGATAGCGTGCCTGAAACTGAAGACTTGAT
GGACCAACAAGACGATGCACCTATTATCCGTCTGATTAATGCATTATTGTCCGAGGCGATACGTCTAAACGCCTCAGATA
TCCATATTGAAACCTTTGAAAAACGCTTGGTCGTTCGATTCCGCGTCGATGGTGAGCTTAAAGAAATCATCACACCAAAA
CGTCAATTAGCGCCGTTATTAGTATCGCGTATTAAAGTGATGGCAAAACTGGATATCGCTGAAAAGCGCGTGCCGCAAGA
TGGGCGTATTAGCTTGCGCTTAGCGGGGCGCGAGGTTGATGTGCGGGTATCGACATTGCCGTCAAGTTTTGGTGAGCGTG
TGGTCATGCGCTTACTAGATAAGCAAGCAGGTCGCCTGAATATGACCTATTTGGGTCTATCTGATAATGATTATAGTGAG
CTTAAGCGCTTAATCCATCGCCCGCATGGCATTATTTTAGTGACAGGACCGACAGGCTCGGGTAAAACCACCACGCTATA
TTCCGCATTGACTGATTTAAATGATCAAACCCGTAATATCTTGACGGCTGAAGATCCAATTGAATTTCAGCTCGATGGTA
TTGGGCAAACGCAGGTCAATAATAAAGTCGATATGACCTTTGCTAAGAGCTTGCGTGCAATGTTGCGTCAAGACCCAGAC
GTGGTCATGGTGGGTGAAATTCGCGATTTAGAGACAGCAGAAATCGCTGTGCAAGCATCTTTAACAGGGCATTTGGTCTT
ATCAACCCTACATACCAACACCGCTATTGGAGCGGTTACGCGCTTGCAAGATATGGGTGTTGAGCCGTTTTTATTATCAT
CATCATTGATAGGCGTGGTCGCCCAGCGTTTGGTACGTACGTTATGTACACATTGTCATGATTGGCAAATAGCTGACCCT
GAACAAGCCAAATTGTTTACTGAGATTGGTATTCAATCAATGTCTGACAATATTGCAGCTAACAATGCTGCTGATAATCT
GACAGATAAAGCTATCAAGCTACCTAGAGCAGTCGGCTGCGATAAGTGTAACCAATCAGGCTTCAAAGGGCGAACAGCGA
TATATGAAGTGGTGCCCGTTGATGATGCGCTGCGACGCATGATTCATAGCAATACCGCCGAGTATGAGCTAGAAGAGTAC
GCCCGCCAAAAGACACCATCAATTCGTGCTGATGGTTTGCGTAAGGTAATCGCGGGACGTACGACATTAGAAGAAGTGCT
ACGCGTGACCAAAGAAAGCGCCCTACTTGAGGACGCTTTGATTGTTTAG

Upstream 100 bases:

>100_bases
CTTGCAGTCTTTTTGAGTTGAGCCAGTTAAGAATAATACATTTACCATGCTTTGATACAAGTTTTTTTCTGAGTTTTTCT
TTATCTATTAGGTCGTTTTT

Downstream 100 bases:

>100_bases
AGTAATATTTTAAGAGACATTTTTATTTGACAGCGATACATTCAACTTCAACGCTGGCACCTGCCGCCAATTCAGCTACG
CCAAAAGCTGAACGGACGGG

Product: type II secretion system protein E

Products: NA

Alternate protein names: Type II traffic warden ATPase [H]

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MMQLPYSFAKRHQILVILAIDPELPPTLLLTKVTPLSAINEAVRFLQQQGIRGVPIYESVSSDDFEKRMNAAYAGNTGES
QHIAAGLEDHPDLDSLADSVPETEDLMDQQDDAPIIRLINALLSEAIRLNASDIHIETFEKRLVVRFRVDGELKEIITPK
RQLAPLLVSRIKVMAKLDIAEKRVPQDGRISLRLAGREVDVRVSTLPSSFGERVVMRLLDKQAGRLNMTYLGLSDNDYSE
LKRLIHRPHGIILVTGPTGSGKTTTLYSALTDLNDQTRNILTAEDPIEFQLDGIGQTQVNNKVDMTFAKSLRAMLRQDPD
VVMVGEIRDLETAEIAVQASLTGHLVLSTLHTNTAIGAVTRLQDMGVEPFLLSSSLIGVVAQRLVRTLCTHCHDWQIADP
EQAKLFTEIGIQSMSDNIAANNAADNLTDKAIKLPRAVGCDKCNQSGFKGRTAIYEVVPVDDALRRMIHSNTAEYELEEY
ARQKTPSIRADGLRKVIAGRTTLEEVLRVTKESALLEDALIV

Sequences:

>Translated_522_residues
MMQLPYSFAKRHQILVILAIDPELPPTLLLTKVTPLSAINEAVRFLQQQGIRGVPIYESVSSDDFEKRMNAAYAGNTGES
QHIAAGLEDHPDLDSLADSVPETEDLMDQQDDAPIIRLINALLSEAIRLNASDIHIETFEKRLVVRFRVDGELKEIITPK
RQLAPLLVSRIKVMAKLDIAEKRVPQDGRISLRLAGREVDVRVSTLPSSFGERVVMRLLDKQAGRLNMTYLGLSDNDYSE
LKRLIHRPHGIILVTGPTGSGKTTTLYSALTDLNDQTRNILTAEDPIEFQLDGIGQTQVNNKVDMTFAKSLRAMLRQDPD
VVMVGEIRDLETAEIAVQASLTGHLVLSTLHTNTAIGAVTRLQDMGVEPFLLSSSLIGVVAQRLVRTLCTHCHDWQIADP
EQAKLFTEIGIQSMSDNIAANNAADNLTDKAIKLPRAVGCDKCNQSGFKGRTAIYEVVPVDDALRRMIHSNTAEYELEEY
ARQKTPSIRADGLRKVIAGRTTLEEVLRVTKESALLEDALIV
>Mature_522_residues
MMQLPYSFAKRHQILVILAIDPELPPTLLLTKVTPLSAINEAVRFLQQQGIRGVPIYESVSSDDFEKRMNAAYAGNTGES
QHIAAGLEDHPDLDSLADSVPETEDLMDQQDDAPIIRLINALLSEAIRLNASDIHIETFEKRLVVRFRVDGELKEIITPK
RQLAPLLVSRIKVMAKLDIAEKRVPQDGRISLRLAGREVDVRVSTLPSSFGERVVMRLLDKQAGRLNMTYLGLSDNDYSE
LKRLIHRPHGIILVTGPTGSGKTTTLYSALTDLNDQTRNILTAEDPIEFQLDGIGQTQVNNKVDMTFAKSLRAMLRQDPD
VVMVGEIRDLETAEIAVQASLTGHLVLSTLHTNTAIGAVTRLQDMGVEPFLLSSSLIGVVAQRLVRTLCTHCHDWQIADP
EQAKLFTEIGIQSMSDNIAANNAADNLTDKAIKLPRAVGCDKCNQSGFKGRTAIYEVVPVDDALRRMIHSNTAEYELEEY
ARQKTPSIRADGLRKVIAGRTTLEEVLRVTKESALLEDALIV

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins. Required for the translocation of a variety of enzymes across the outer membrane [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=459, Percent_Identity=57.9520697167756, Blast_Score=523, Evalue=1e-149,
Organism=Escherichia coli, GI1786296, Length=420, Percent_Identity=42.1428571428571, Blast_Score=316, Evalue=3e-87,
Organism=Escherichia coli, GI87082188, Length=169, Percent_Identity=43.7869822485207, Blast_Score=110, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013369
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 57777; Mature: 57777

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQLPYSFAKRHQILVILAIDPELPPTLLLTKVTPLSAINEAVRFLQQQGIRGVPIYESV
CCCCCHHHHCCCEEEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCC
SSDDFEKRMNAAYAGNTGESQHIAAGLEDHPDLDSLADSVPETEDLMDQQDDAPIIRLIN
CCHHHHHHHHHHCCCCCCCCCCEECCCCCCCCHHHHHHCCCCHHHHHCCCCCCHHHHHHH
ALLSEAIRLNASDIHIETFEKRLVVRFRVDGELKEIITPKRQLAPLLVSRIKVMAKLDIA
HHHHHHHHCCCCCEEHEECCCEEEEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
EKRVPQDGRISLRLAGREVDVRVSTLPSSFGERVVMRLLDKQAGRLNMTYLGLSDNDYSE
HHCCCCCCCEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHH
LKRLIHRPHGIILVTGPTGSGKTTTLYSALTDLNDQTRNILTAEDPIEFQLDGIGQTQVN
HHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHCCEEECCCCCEEEECCCCCCCCC
NKVDMTFAKSLRAMLRQDPDVVMVGEIRDLETAEIAVQASLTGHLVLSTLHTNTAIGAVT
CCHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHEEEEECCCCEEEEEEHHCCHHHHHHH
RLQDMGVEPFLLSSSLIGVVAQRLVRTLCTHCHDWQIADPEQAKLFTEIGIQSMSDNIAA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
NNAADNLTDKAIKLPRAVGCDKCNQSGFKGRTAIYEVVPVDDALRRMIHSNTAEYELEEY
CCCCCHHHHHHHHCCHHCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCHHHHHH
ARQKTPSIRADGLRKVIAGRTTLEEVLRVTKESALLEDALIV
HHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMQLPYSFAKRHQILVILAIDPELPPTLLLTKVTPLSAINEAVRFLQQQGIRGVPIYESV
CCCCCHHHHCCCEEEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCC
SSDDFEKRMNAAYAGNTGESQHIAAGLEDHPDLDSLADSVPETEDLMDQQDDAPIIRLIN
CCHHHHHHHHHHCCCCCCCCCCEECCCCCCCCHHHHHHCCCCHHHHHCCCCCCHHHHHHH
ALLSEAIRLNASDIHIETFEKRLVVRFRVDGELKEIITPKRQLAPLLVSRIKVMAKLDIA
HHHHHHHHCCCCCEEHEECCCEEEEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
EKRVPQDGRISLRLAGREVDVRVSTLPSSFGERVVMRLLDKQAGRLNMTYLGLSDNDYSE
HHCCCCCCCEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHH
LKRLIHRPHGIILVTGPTGSGKTTTLYSALTDLNDQTRNILTAEDPIEFQLDGIGQTQVN
HHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHCCEEECCCCCEEEECCCCCCCCC
NKVDMTFAKSLRAMLRQDPDVVMVGEIRDLETAEIAVQASLTGHLVLSTLHTNTAIGAVT
CCHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHEEEEECCCCEEEEEEHHCCHHHHHHH
RLQDMGVEPFLLSSSLIGVVAQRLVRTLCTHCHDWQIADPEQAKLFTEIGIQSMSDNIAA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
NNAADNLTDKAIKLPRAVGCDKCNQSGFKGRTAIYEVVPVDDALRRMIHSNTAEYELEEY
CCCCCHHHHHHHHCCHHCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCHHHHHH
ARQKTPSIRADGLRKVIAGRTTLEEVLRVTKESALLEDALIV
HHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1588814; 10984043 [H]