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The map label for this gene is pgi [H]

Identifier: 93004949

GI number: 93004949

Start: 139471

End: 141138

Strand: Direct

Name: pgi [H]

Synonym: Pcryo_0118

Alternate gene names: 93004949

Gene position: 139471-141138 (Clockwise)

Preceding gene: 93004948

Following gene: 93004950

Centisome position: 4.56

GC content: 44.42

Gene sequence:

>1668_bases
ATGAACGATACAAAAGACAATAAAGTCTATAGCAGTGCCCGCCATTCTAAATATTGGCAGAAGCTGAAGGCAGCAGCTGA
GTCGAAGTGGTCATTAGCTGCCTTGTTTGCACAAGATAATACGCGTACCCAACGTTTTAGTGCTCAAAGTGGGGCGCTGT
ATATGGACTACAGCAAGCAATGTTTAGATGATACTGTGCTAGAAAGTTTATTAAATCTGGCAAATAGTTGTGAATTGTCT
GCTCGTATTCAGGCCTTGCTACAAGGGGCGATGGTGAATACCAGTGAAGAACGTGCCGCTTTGCATACTGCACTACGATT
GCCCACCACAGCAAATTTACAACTTGATAATCAAGATGTAGTCGCTGATGTCCATCAAAGTTTGGGGCAAGTTGAACGCT
TATCGGAGCGTGTACGCAGTGGGACATGGCGCGGGTTTTCAGGTAAAGCGATTACAGATGTTGTTAATATCGGTGTAGGG
GGTTCTGACTTAGGGCCACTGATGGCAACCACTGCCCTTGATGAGTGGGCAGATACCTGTGTTGAGGTCCATTTCGTCTC
CAATATGGATGGCACGCAGCTGGATAATTTGCTAAAACATCTGAATCCTGAAACCACTTTATTTATTATCTCATCTAAAT
CTTTTGGTACCATTGATACCTTATCCAATGCCAAAACGGCACTATCATGGCTGCTTGCAACCGCAAAGCTGCGTGCGGGC
ACTGAAGACAGTGTATTACGTCGTCATTTCATCGGTATCTCGGCCAATAGTGAAAAAATGAGTGCTTGGGGTATTCATCC
TGAGCACCAGTTGCAGCTTTGGGAATGGGTAGGGGGCCGTTTTTCTTTATGGTCAGCGATTGGTCTTGCCATAGCTATTC
GTATCGGTATGTCTGGGTTTAAAGAGCTGTTGGCAGGCGCGCATAGTATGGATGAGCATTTTGCGCAGGCGGATTTTGCA
GAAAACTTACCGGTATTATTGGGCTTAATCGCAGTTTGGAATAGCACCTTTTTGCAGGTAAATGCTCATACTGTGCTGCC
TTATGATGGGCGCTTAAGCTATTTACCCAGTTATTTAACTCAGCTAGAGATGGAAAGTAATGGTAAATCGGTGACCCAGC
ATGGTGATCGTATTGATTATGATACCTGTCCTATTCTTTGGGGTGAAATTGGTTCTAATGCCCAACATGCTTTTTATCAG
CTGCTACATCAAGGAACGCAGCAAGTCTCTTGTGATTTTATCGCTTGTGTACGTCGCTACAGTGATAAGGCAAAAAATAC
GCCACTACAACAGCAGCATGAACTGTCTTTAGCCAATTGTTTGGCTCAAAGCCGTGTACTGGCTTTTGGTAATGCTGCTA
TCGCTGAAACGGATAGTCAAATTGCTTGTGATGCTGATAAATATAAATACTACCGAGGCAACCAGCCTTCTACAACCTTG
CTGATTGATGAACTTACTCCGCATAGCTTAGGGGCGTTAATCGCGCTTTATGAGCATAAGGTTTATGTTATGGCTAGTAT
CTGGGATATCAATCCATTTGATCAATGGGGCGTTGAGATGGGTAAGCAGATGGCAGAGTCCGTTCATGATGCGATGCAGC
AAGAGGGTAACGCACCATTCGATACCTCAACCAATCAGCTGTTAAAACATATCAAACAGCTTTCTTGA

Upstream 100 bases:

>100_bases
GACCATGCGTGGTAACAGTTATGATGCTGGCGATATGCGCTCTTATATGCAAGCCTTTATATATTTCGCTCAGCAGCAAC
TAGCCGATGAAGAGTAGTTA

Downstream 100 bases:

>100_bases
GAGCGCTGCTATATTAATAACGACTAAAGGTACACTCATGAGCGCCGAGACTATGGATAAAAACATGCCCCAATCTGAAT
CCAATTCGTTTAGCGATTTG

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MNDTKDNKVYSSARHSKYWQKLKAAAESKWSLAALFAQDNTRTQRFSAQSGALYMDYSKQCLDDTVLESLLNLANSCELS
ARIQALLQGAMVNTSEERAALHTALRLPTTANLQLDNQDVVADVHQSLGQVERLSERVRSGTWRGFSGKAITDVVNIGVG
GSDLGPLMATTALDEWADTCVEVHFVSNMDGTQLDNLLKHLNPETTLFIISSKSFGTIDTLSNAKTALSWLLATAKLRAG
TEDSVLRRHFIGISANSEKMSAWGIHPEHQLQLWEWVGGRFSLWSAIGLAIAIRIGMSGFKELLAGAHSMDEHFAQADFA
ENLPVLLGLIAVWNSTFLQVNAHTVLPYDGRLSYLPSYLTQLEMESNGKSVTQHGDRIDYDTCPILWGEIGSNAQHAFYQ
LLHQGTQQVSCDFIACVRRYSDKAKNTPLQQQHELSLANCLAQSRVLAFGNAAIAETDSQIACDADKYKYYRGNQPSTTL
LIDELTPHSLGALIALYEHKVYVMASIWDINPFDQWGVEMGKQMAESVHDAMQQEGNAPFDTSTNQLLKHIKQLS

Sequences:

>Translated_555_residues
MNDTKDNKVYSSARHSKYWQKLKAAAESKWSLAALFAQDNTRTQRFSAQSGALYMDYSKQCLDDTVLESLLNLANSCELS
ARIQALLQGAMVNTSEERAALHTALRLPTTANLQLDNQDVVADVHQSLGQVERLSERVRSGTWRGFSGKAITDVVNIGVG
GSDLGPLMATTALDEWADTCVEVHFVSNMDGTQLDNLLKHLNPETTLFIISSKSFGTIDTLSNAKTALSWLLATAKLRAG
TEDSVLRRHFIGISANSEKMSAWGIHPEHQLQLWEWVGGRFSLWSAIGLAIAIRIGMSGFKELLAGAHSMDEHFAQADFA
ENLPVLLGLIAVWNSTFLQVNAHTVLPYDGRLSYLPSYLTQLEMESNGKSVTQHGDRIDYDTCPILWGEIGSNAQHAFYQ
LLHQGTQQVSCDFIACVRRYSDKAKNTPLQQQHELSLANCLAQSRVLAFGNAAIAETDSQIACDADKYKYYRGNQPSTTL
LIDELTPHSLGALIALYEHKVYVMASIWDINPFDQWGVEMGKQMAESVHDAMQQEGNAPFDTSTNQLLKHIKQLS
>Mature_555_residues
MNDTKDNKVYSSARHSKYWQKLKAAAESKWSLAALFAQDNTRTQRFSAQSGALYMDYSKQCLDDTVLESLLNLANSCELS
ARIQALLQGAMVNTSEERAALHTALRLPTTANLQLDNQDVVADVHQSLGQVERLSERVRSGTWRGFSGKAITDVVNIGVG
GSDLGPLMATTALDEWADTCVEVHFVSNMDGTQLDNLLKHLNPETTLFIISSKSFGTIDTLSNAKTALSWLLATAKLRAG
TEDSVLRRHFIGISANSEKMSAWGIHPEHQLQLWEWVGGRFSLWSAIGLAIAIRIGMSGFKELLAGAHSMDEHFAQADFA
ENLPVLLGLIAVWNSTFLQVNAHTVLPYDGRLSYLPSYLTQLEMESNGKSVTQHGDRIDYDTCPILWGEIGSNAQHAFYQ
LLHQGTQQVSCDFIACVRRYSDKAKNTPLQQQHELSLANCLAQSRVLAFGNAAIAETDSQIACDADKYKYYRGNQPSTTL
LIDELTPHSLGALIALYEHKVYVMASIWDINPFDQWGVEMGKQMAESVHDAMQQEGNAPFDTSTNQLLKHIKQLS

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=544, Percent_Identity=42.2794117647059, Blast_Score=458, Evalue=1e-129,
Organism=Homo sapiens, GI296080693, Length=542, Percent_Identity=38.5608856088561, Blast_Score=393, Evalue=1e-109,
Organism=Escherichia coli, GI1790457, Length=534, Percent_Identity=43.0711610486891, Blast_Score=461, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI71996708, Length=543, Percent_Identity=42.3572744014733, Blast_Score=441, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI71996703, Length=543, Percent_Identity=42.3572744014733, Blast_Score=440, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6319673, Length=551, Percent_Identity=39.5644283121597, Blast_Score=422, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24651916, Length=551, Percent_Identity=43.1941923774955, Blast_Score=460, Evalue=1e-129,
Organism=Drosophila melanogaster, GI24651914, Length=551, Percent_Identity=43.1941923774955, Blast_Score=460, Evalue=1e-129,
Organism=Drosophila melanogaster, GI17737445, Length=551, Percent_Identity=43.1941923774955, Blast_Score=460, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 61433; Mature: 61433

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTKDNKVYSSARHSKYWQKLKAAAESKWSLAALFAQDNTRTQRFSAQSGALYMDYSKQ
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHCCCCCCEEECCCHH
CLDDTVLESLLNLANSCELSARIQALLQGAMVNTSEERAALHTALRLPTTANLQLDNQDV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEECCHHH
VADVHQSLGQVERLSERVRSGTWRGFSGKAITDVVNIGVGGSDLGPLMATTALDEWADTC
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
VEVHFVSNMDGTQLDNLLKHLNPETTLFIISSKSFGTIDTLSNAKTALSWLLATAKLRAG
EEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCC
TEDSVLRRHFIGISANSEKMSAWGIHPEHQLQLWEWVGGRFSLWSAIGLAIAIRIGMSGF
CHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
KELLAGAHSMDEHFAQADFAENLPVLLGLIAVWNSTFLQVNAHTVLPYDGRLSYLPSYLT
HHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEECEEEECCCCCHHHHHHHHH
QLEMESNGKSVTQHGDRIDYDTCPILWGEIGSNAQHAFYQLLHQGTQQVSCDFIACVRRY
HHHHCCCCCHHHHCCCCCCCCCCCEEHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHH
SDKAKNTPLQQQHELSLANCLAQSRVLAFGNAAIAETDSQIACDADKYKYYRGNQPSTTL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCEEECCHHHHEECCCCCCCEE
LIDELTPHSLGALIALYEHKVYVMASIWDINPFDQWGVEMGKQMAESVHDAMQQEGNAPF
EEECCCCHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DTSTNQLLKHIKQLS
CCCHHHHHHHHHHCC
>Mature Secondary Structure
MNDTKDNKVYSSARHSKYWQKLKAAAESKWSLAALFAQDNTRTQRFSAQSGALYMDYSKQ
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHCCCCCCEEECCCHH
CLDDTVLESLLNLANSCELSARIQALLQGAMVNTSEERAALHTALRLPTTANLQLDNQDV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEECCHHH
VADVHQSLGQVERLSERVRSGTWRGFSGKAITDVVNIGVGGSDLGPLMATTALDEWADTC
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
VEVHFVSNMDGTQLDNLLKHLNPETTLFIISSKSFGTIDTLSNAKTALSWLLATAKLRAG
EEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCC
TEDSVLRRHFIGISANSEKMSAWGIHPEHQLQLWEWVGGRFSLWSAIGLAIAIRIGMSGF
CHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
KELLAGAHSMDEHFAQADFAENLPVLLGLIAVWNSTFLQVNAHTVLPYDGRLSYLPSYLT
HHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEECEEEECCCCCHHHHHHHHH
QLEMESNGKSVTQHGDRIDYDTCPILWGEIGSNAQHAFYQLLHQGTQQVSCDFIACVRRY
HHHHCCCCCHHHHCCCCCCCCCCCEEHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHH
SDKAKNTPLQQQHELSLANCLAQSRVLAFGNAAIAETDSQIACDADKYKYYRGNQPSTTL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCEEECCHHHHEECCCCCCCEE
LIDELTPHSLGALIALYEHKVYVMASIWDINPFDQWGVEMGKQMAESVHDAMQQEGNAPF
EEECCCCHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DTSTNQLLKHIKQLS
CCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA