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The map label for this gene is udg [H]

Identifier: 93004950

GI number: 93004950

Start: 141176

End: 142588

Strand: Direct

Name: udg [H]

Synonym: Pcryo_0119

Alternate gene names: 93004950

Gene position: 141176-142588 (Clockwise)

Preceding gene: 93004949

Following gene: 93004952

Centisome position: 4.61

GC content: 44.09

Gene sequence:

>1413_bases
ATGAGCGCCGAGACTATGGATAAAAACATGCCCCAATCTGAATCCAATTCGTTTAGCGATTTGGCAAAAGAATCTGCTGT
CTGTGTACTTATTGGTCATAGTATTGAGGCGGTGACCAGTGCTGTCGTACTGGCAAGTCTTGGTCAGCAAGTGCATTTAT
ACGCAGACCAAGAGATATTGGCGCAGCAGCTACATCAATATGGCTTTGAGCATCATTTGCAGGCACTATGGCAAATGTAT
ACGCAGCAACAGCATATTGTTAGTTATGAGCTGCCTAATAACGCTGATAGGCTTATACAGCTTTATGAAGTAGCAGATCA
TAGCAATACGAAAGCTATCGAAGAGCAGCAAAAGGTAAATCAACCAAAATCAGTAATCCTATATTGGTTGTTTTTAGACA
GTGTAGATTCGGTATGGGTAGAGGATGATTGGATTACCGCCTTTAATCATAGTCAACAGCAGACACAACCGTTCATGATG
AGTGGCATTAAGCCGCTTGGCACTATAGATGCATTGTCTCAGCGCTTAAAGCGTGCTTGGGTCTATTATCTACCGTTCGT
TTTCTTAAAAGATGGTGATGCTTATAGCTCGATGTTAAATCCGTCACTATGGCTACTCGGTGAAAAAACCTCTAATAGTC
GTCATCATTTGGGTATGCTACAGCCATTAATGCAGCATGCGCGTGCTACTCATTATGCCAATATCGCGACTATCGAATTT
GCTCGTAGTAGCATCATGGCGATGCTCGCAACGCGGGTCAGTTTCATGAATGAGATGTCGCGCTTGGCGGATAGTCAACA
AGTCGATATCCAGCAAGTCAGCCATATCATGGGGCTTGATGAGCGCGTGGGCAGTAGCTACTTGCAGGCGGGCTGGGGAT
TTGGTGGTAATACGCTACCGACAGAATTGCTTCAGCTACAGCAATCAAGTCAAGCACAGAGCTTGGCCATGCCGCTATTA
CAATCGGTTATCCATATTAATGAAGACCAAAAAGAGCTAATATTCCGCAAGTTTTGGCAATATTTTGATGGTTTTATCGA
TAATAAAACGGTCATGATTTGGGGCGGCAGTTATAAAGCCGGCTCAGGACGGACGGCAGAGTCGGCGATTCATCCTTTAT
TGGCATTATTGTGGTCTTATAATATTCGCACGCTGGTCTATAGTGATAAAGCGCAAACGGAGCTAGCAGCGCTTTATAAG
CAGCAGCCATTACTGGAGTTAATAAATAATCCTTATCAAAAGCTTAATGAGGCGCAGGCAATTTTTATTATCAGCTGGTT
GCAAGAGAACCGACTAGATATTGCTAAGCTTAATGAGCAAGCGATGCCCGTATTCGATGCGCAAAATGCCTTGTCACGAA
CGCAGATAGATGGTCTAGTCGGCGACTATATGGGGATTGGTCGCGCTAAATAA

Upstream 100 bases:

>100_bases
GGTAACGCACCATTCGATACCTCAACCAATCAGCTGTTAAAACATATCAAACAGCTTTCTTGAGAGCGCTGCTATATTAA
TAACGACTAAAGGTACACTC

Downstream 100 bases:

>100_bases
GCGCTTTCTATCAAGTATAAAATAAGCTCAGTAGACAAACAGTTGTTAGATTAAAGCTAAATAAAAGCGCCGATTAATAT
AAAAATTAATCGGCGCTTTT

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MSAETMDKNMPQSESNSFSDLAKESAVCVLIGHSIEAVTSAVVLASLGQQVHLYADQEILAQQLHQYGFEHHLQALWQMY
TQQQHIVSYELPNNADRLIQLYEVADHSNTKAIEEQQKVNQPKSVILYWLFLDSVDSVWVEDDWITAFNHSQQQTQPFMM
SGIKPLGTIDALSQRLKRAWVYYLPFVFLKDGDAYSSMLNPSLWLLGEKTSNSRHHLGMLQPLMQHARATHYANIATIEF
ARSSIMAMLATRVSFMNEMSRLADSQQVDIQQVSHIMGLDERVGSSYLQAGWGFGGNTLPTELLQLQQSSQAQSLAMPLL
QSVIHINEDQKELIFRKFWQYFDGFIDNKTVMIWGGSYKAGSGRTAESAIHPLLALLWSYNIRTLVYSDKAQTELAALYK
QQPLLELINNPYQKLNEAQAIFIISWLQENRLDIAKLNEQAMPVFDAQNALSRTQIDGLVGDYMGIGRAK

Sequences:

>Translated_470_residues
MSAETMDKNMPQSESNSFSDLAKESAVCVLIGHSIEAVTSAVVLASLGQQVHLYADQEILAQQLHQYGFEHHLQALWQMY
TQQQHIVSYELPNNADRLIQLYEVADHSNTKAIEEQQKVNQPKSVILYWLFLDSVDSVWVEDDWITAFNHSQQQTQPFMM
SGIKPLGTIDALSQRLKRAWVYYLPFVFLKDGDAYSSMLNPSLWLLGEKTSNSRHHLGMLQPLMQHARATHYANIATIEF
ARSSIMAMLATRVSFMNEMSRLADSQQVDIQQVSHIMGLDERVGSSYLQAGWGFGGNTLPTELLQLQQSSQAQSLAMPLL
QSVIHINEDQKELIFRKFWQYFDGFIDNKTVMIWGGSYKAGSGRTAESAIHPLLALLWSYNIRTLVYSDKAQTELAALYK
QQPLLELINNPYQKLNEAQAIFIISWLQENRLDIAKLNEQAMPVFDAQNALSRTQIDGLVGDYMGIGRAK
>Mature_469_residues
SAETMDKNMPQSESNSFSDLAKESAVCVLIGHSIEAVTSAVVLASLGQQVHLYADQEILAQQLHQYGFEHHLQALWQMYT
QQQHIVSYELPNNADRLIQLYEVADHSNTKAIEEQQKVNQPKSVILYWLFLDSVDSVWVEDDWITAFNHSQQQTQPFMMS
GIKPLGTIDALSQRLKRAWVYYLPFVFLKDGDAYSSMLNPSLWLLGEKTSNSRHHLGMLQPLMQHARATHYANIATIEFA
RSSIMAMLATRVSFMNEMSRLADSQQVDIQQVSHIMGLDERVGSSYLQAGWGFGGNTLPTELLQLQQSSQAQSLAMPLLQ
SVIHINEDQKELIFRKFWQYFDGFIDNKTVMIWGGSYKAGSGRTAESAIHPLLALLWSYNIRTLVYSDKAQTELAALYKQ
QPLLELINNPYQKLNEAQAIFIISWLQENRLDIAKLNEQAMPVFDAQNALSRTQIDGLVGDYMGIGRAK

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296040443, Length=302, Percent_Identity=24.1721854304636, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI296040438, Length=302, Percent_Identity=24.1721854304636, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI4507813, Length=302, Percent_Identity=24.1721854304636, Blast_Score=89, Evalue=8e-18,
Organism=Escherichia coli, GI1788340, Length=240, Percent_Identity=23.3333333333333, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17560350, Length=286, Percent_Identity=26.9230769230769, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI17136908, Length=292, Percent_Identity=24.6575342465753, Blast_Score=89, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 53299; Mature: 53168

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAETMDKNMPQSESNSFSDLAKESAVCVLIGHSIEAVTSAVVLASLGQQVHLYADQEIL
CCCCCCCCCCCCCCCCCHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCEEEEECCHHHH
AQQLHQYGFEHHLQALWQMYTQQQHIVSYELPNNADRLIQLYEVADHSNTKAIEEQQKVN
HHHHHHHCHHHHHHHHHHHHHCHHHEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHCC
QPKSVILYWLFLDSVDSVWVEDDWITAFNHSQQQTQPFMMSGIKPLGTIDALSQRLKRAW
CCHHHEEHHHHHHCCCCEEECCCCEECCCCCHHHCCHHHHHCCCCCCHHHHHHHHHHHHH
VYYLPFVFLKDGDAYSSMLNPSLWLLGEKTSNSRHHLGMLQPLMQHARATHYANIATIEF
HHHHCEEEEECCCHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHH
ARSSIMAMLATRVSFMNEMSRLADSQQVDIQQVSHIMGLDERVGSSYLQAGWGFGGNTLP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHH
TELLQLQQSSQAQSLAMPLLQSVIHINEDQKELIFRKFWQYFDGFIDNKTVMIWGGSYKA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
GSGRTAESAIHPLLALLWSYNIRTLVYSDKAQTELAALYKQQPLLELINNPYQKLNEAQA
CCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCHHHHHHCCHHHHHCCCCE
IFIISWLQENRLDIAKLNEQAMPVFDAQNALSRTQIDGLVGDYMGIGRAK
EEEEEHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SAETMDKNMPQSESNSFSDLAKESAVCVLIGHSIEAVTSAVVLASLGQQVHLYADQEIL
CCCCCCCCCCCCCCCCHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCEEEEECCHHHH
AQQLHQYGFEHHLQALWQMYTQQQHIVSYELPNNADRLIQLYEVADHSNTKAIEEQQKVN
HHHHHHHCHHHHHHHHHHHHHCHHHEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHCC
QPKSVILYWLFLDSVDSVWVEDDWITAFNHSQQQTQPFMMSGIKPLGTIDALSQRLKRAW
CCHHHEEHHHHHHCCCCEEECCCCEECCCCCHHHCCHHHHHCCCCCCHHHHHHHHHHHHH
VYYLPFVFLKDGDAYSSMLNPSLWLLGEKTSNSRHHLGMLQPLMQHARATHYANIATIEF
HHHHCEEEEECCCHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHH
ARSSIMAMLATRVSFMNEMSRLADSQQVDIQQVSHIMGLDERVGSSYLQAGWGFGGNTLP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHH
TELLQLQQSSQAQSLAMPLLQSVIHINEDQKELIFRKFWQYFDGFIDNKTVMIWGGSYKA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
GSGRTAESAIHPLLALLWSYNIRTLVYSDKAQTELAALYKQQPLLELINNPYQKLNEAQA
CCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCHHHHHHCCHHHHHCCCCE
IFIISWLQENRLDIAKLNEQAMPVFDAQNALSRTQIDGLVGDYMGIGRAK
EEEEEHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]