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The map label for this gene is sucD [H]

Identifier: 93004946

GI number: 93004946

Start: 136506

End: 137381

Strand: Direct

Name: sucD [H]

Synonym: Pcryo_0115

Alternate gene names: 93004946

Gene position: 136506-137381 (Clockwise)

Preceding gene: 93004945

Following gene: 93004947

Centisome position: 4.46

GC content: 45.09

Gene sequence:

>876_bases
ATGAGTGTATTAATTGATAAAGACACCAAAGTATTGGTGCAAGGTTTTACCGGTAAAAATGGTACGTTCCACTCAGAACA
AGCCATCGAATATGGTACAAAAGTTGTTGGCGGCGTAACCCCAGGTAAAGGCGGTCAAACGCACCTAGGTTTGCCAGTAT
TCAACACCATGTCTGAAGCAATGGCAGCCACCCAAGCAGACGCTTCTGTTATCTATGTACCAGCTCCTTTTGTACTAGAT
TCTATCATCGAAGCAATTGATGCTGGTGTGAAGCTAATTGTTGTGATCACTGAAGGTGTACCAACGCTTGATATGCTTAA
AGCCAAACGCTACCTTGAAACAGCAGGCGATGTACGTCTAATCGGTCCTAACTGCCCAGGCGTTATCACCCCAGGTCAGT
GCAAAATCGGCATCATGCCAGGTCATATCCATTTGCCAGGTAAAGTGGGTATCATCTCACGCTCTGGTACTTTAACTTAT
GAAGCCGTTGCTCAAACCACTAAGCTTGGTTTTGGTCAATCAACCTGTATCGGTATCGGTGGTGATCCGATCCCTGGTAT
GAACCAGATTGATGCGCTTAAATTGTTCCAAGAAGATCCACAAACTGAAGCAATTATCTTAATCGGTGAAATTGGTGGTA
CTGCTGAAGAAGAAGCAGCCGCTTATATCAAAGACCATGTAACTAAGCCAGTTGTTGGTTATATTGCTGGTGTAACTGCT
CCTGAAGGTAAGCGTATGGGTCATGCCGGCGCTATCATCTCTGGCGGTCAAGGTACAGCTGAAGATAAATTTAAAGCGTT
TGAAGCGGCAGGTATTGCTTACACGCGTGACCCATCAAAATTGGGCGAGAAGCTAAAAGAAGTGACAGGTTGGTAG

Upstream 100 bases:

>100_bases
TCAAGAGTATAAGGCGTTTGCTGTTATTCTACCGACGTTAACATTTAACGTGGCAGGATAGGCAAGCGCCTACCAGACAA
CCGCATACAAGGATAAGATA

Downstream 100 bases:

>100_bases
TATCAGTAGCTAACTGACTGTTAATACTCAAATGACGTTGAAAAATAATGAAGGCACCCCTACAATGGGGTGTCTTTTTT
TGTTTGAAAATTGCTTTGGA

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MSVLIDKDTKVLVQGFTGKNGTFHSEQAIEYGTKVVGGVTPGKGGQTHLGLPVFNTMSEAMAATQADASVIYVPAPFVLD
SIIEAIDAGVKLIVVITEGVPTLDMLKAKRYLETAGDVRLIGPNCPGVITPGQCKIGIMPGHIHLPGKVGIISRSGTLTY
EAVAQTTKLGFGQSTCIGIGGDPIPGMNQIDALKLFQEDPQTEAIILIGEIGGTAEEEAAAYIKDHVTKPVVGYIAGVTA
PEGKRMGHAGAIISGGQGTAEDKFKAFEAAGIAYTRDPSKLGEKLKEVTGW

Sequences:

>Translated_291_residues
MSVLIDKDTKVLVQGFTGKNGTFHSEQAIEYGTKVVGGVTPGKGGQTHLGLPVFNTMSEAMAATQADASVIYVPAPFVLD
SIIEAIDAGVKLIVVITEGVPTLDMLKAKRYLETAGDVRLIGPNCPGVITPGQCKIGIMPGHIHLPGKVGIISRSGTLTY
EAVAQTTKLGFGQSTCIGIGGDPIPGMNQIDALKLFQEDPQTEAIILIGEIGGTAEEEAAAYIKDHVTKPVVGYIAGVTA
PEGKRMGHAGAIISGGQGTAEDKFKAFEAAGIAYTRDPSKLGEKLKEVTGW
>Mature_290_residues
SVLIDKDTKVLVQGFTGKNGTFHSEQAIEYGTKVVGGVTPGKGGQTHLGLPVFNTMSEAMAATQADASVIYVPAPFVLDS
IIEAIDAGVKLIVVITEGVPTLDMLKAKRYLETAGDVRLIGPNCPGVITPGQCKIGIMPGHIHLPGKVGIISRSGTLTYE
AVAQTTKLGFGQSTCIGIGGDPIPGMNQIDALKLFQEDPQTEAIILIGEIGGTAEEEAAAYIKDHVTKPVVGYIAGVTAP
EGKRMGHAGAIISGGQGTAEDKFKAFEAAGIAYTRDPSKLGEKLKEVTGW

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=284, Percent_Identity=62.6760563380282, Blast_Score=312, Evalue=2e-85,
Organism=Homo sapiens, GI38569423, Length=258, Percent_Identity=31.3953488372093, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI38569421, Length=258, Percent_Identity=31.3953488372093, Blast_Score=107, Evalue=1e-23,
Organism=Escherichia coli, GI1786949, Length=288, Percent_Identity=77.0833333333333, Blast_Score=450, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17550194, Length=288, Percent_Identity=62.8472222222222, Blast_Score=346, Evalue=8e-96,
Organism=Caenorhabditis elegans, GI17553126, Length=290, Percent_Identity=60, Blast_Score=332, Evalue=2e-91,
Organism=Caenorhabditis elegans, GI17557344, Length=310, Percent_Identity=30.3225806451613, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17551266, Length=312, Percent_Identity=30.4487179487179, Blast_Score=108, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6324716, Length=292, Percent_Identity=52.7397260273973, Blast_Score=282, Evalue=4e-77,
Organism=Drosophila melanogaster, GI21356559, Length=290, Percent_Identity=57.2413793103448, Blast_Score=337, Evalue=6e-93,
Organism=Drosophila melanogaster, GI28574296, Length=288, Percent_Identity=60.0694444444444, Blast_Score=321, Evalue=4e-88,
Organism=Drosophila melanogaster, GI281363477, Length=262, Percent_Identity=32.0610687022901, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI281363475, Length=262, Percent_Identity=32.0610687022901, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI281363473, Length=262, Percent_Identity=32.0610687022901, Blast_Score=107, Evalue=8e-24,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30271; Mature: 30140

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLIDKDTKVLVQGFTGKNGTFHSEQAIEYGTKVVGGVTPGKGGQTHLGLPVFNTMSEA
CCEEECCCCEEEEEECCCCCCCCCCHHHHHHCCCEECCCCCCCCCCEEECCHHHHHHHHH
MAATQADASVIYVPAPFVLDSIIEAIDAGVKLIVVITEGVPTLDMLKAKRYLETAGDVRL
HHHHCCCCEEEEECCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEE
IGPNCPGVITPGQCKIGIMPGHIHLPGKVGIISRSGTLTYEAVAQTTKLGFGQSTCIGIG
ECCCCCCEECCCCEEEEEECCEEECCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECC
GDPIPGMNQIDALKLFQEDPQTEAIILIGEIGGTAEEEAAAYIKDHVTKPVVGYIAGVTA
CCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHCCCC
PEGKRMGHAGAIISGGQGTAEDKFKAFEAAGIAYTRDPSKLGEKLKEVTGW
CCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCEEECCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVLIDKDTKVLVQGFTGKNGTFHSEQAIEYGTKVVGGVTPGKGGQTHLGLPVFNTMSEA
CEEECCCCEEEEEECCCCCCCCCCHHHHHHCCCEECCCCCCCCCCEEECCHHHHHHHHH
MAATQADASVIYVPAPFVLDSIIEAIDAGVKLIVVITEGVPTLDMLKAKRYLETAGDVRL
HHHHCCCCEEEEECCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEE
IGPNCPGVITPGQCKIGIMPGHIHLPGKVGIISRSGTLTYEAVAQTTKLGFGQSTCIGIG
ECCCCCCEECCCCEEEEEECCEEECCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECC
GDPIPGMNQIDALKLFQEDPQTEAIILIGEIGGTAEEEAAAYIKDHVTKPVVGYIAGVTA
CCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHCCCC
PEGKRMGHAGAIISGGQGTAEDKFKAFEAAGIAYTRDPSKLGEKLKEVTGW
CCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCEEECCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]