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The map label for this gene is galE [H]

Identifier: 93004947

GI number: 93004947

Start: 137429

End: 138529

Strand: Direct

Name: galE [H]

Synonym: Pcryo_0116

Alternate gene names: 93004947

Gene position: 137429-138529 (Clockwise)

Preceding gene: 93004946

Following gene: 93004948

Centisome position: 4.49

GC content: 40.69

Gene sequence:

>1101_bases
ATGAAGGCACCCCTACAATGGGGTGTCTTTTTTTGTTTGAAAATTGCTTTGGATATCAATATGGAAAATTATAAAAATAA
AATATTAGTGACTGGAGGCGCAGGATATATCGGTTCACATACTTGTATTGCACTGCATGAAGCAGGCTACGAGGTGGTGA
TATATGACAATTTATCTAACAGCAGTTTTGAGGCAGTAAATCGTGTTTCTAGCCTTATTGGGCAGCCTATCGACTTTATC
GAAGGCGACATTCGTGATGCTGATTCACTCAGGCAAGTATTTGTCGCCCATCGATTTTTTGGCGTGATTCATTTTGCTGG
CTTAAAAGCGGTGGGCGAATCTGTCGCTAAACCCTTGATGTATTATGATAATAATGTGAGTGGTACGATTACCTTACTTA
AAATCATGGCTGAATATGAGGTTAAAAAACTAGTCTTTTCTTCATCAGCTACGGTCTATGGTGATCCTGAAATTCTGCCC
ATTAATGAAGACTCTCCACGCTCCTGTACCAATCCTTATGGACAGAGTAAGCTTACGGTTGAGCATGTTCTAGAAGATTT
AGCGCTATCAGATAACAGCTGGAGCCTTATTCCTTTGAGGTATTTTAATCCTGTTGGCGCGCACCCATCTGGACAAATTG
GCGAAGATCCCAATGATATTCCAAATAATTTAATGCCATATATCTCACAAGTCGCGGTCGGCAAGCTTGATAAATTAAGC
ATTTTTGGCGATGACTATGCTACGGTAGATGGTACGGGTGTGCGTGACTTTATACATGTAACTGACCTCGCACAAGGTCA
TGTCGCCGCGCTCAATTATCTAAAGCAGCAAAAGCAAAGCTTAGGTTTTCTTCCGATCAATTTAGGATCAGGTAAGGGAA
CGTCTGTATTAGAGTTAGTTAGAGCGTTTTCTGCCGTATCAGCTAAAGATATTCCTTTTCAGTTTGTTGGGCGACGAGCT
GGTGATATTGCCAGTTGCTATGCTAGTGCTGATAAAGCACAAGAGTTATTAGGATGGAAGGCAAGCTTATCTATTACTGA
TATGTGTCAAGATACATGGCGTTGGCAAAGCATAAATCCAAATGGTTATAACTCAATATAA

Upstream 100 bases:

>100_bases
CGCGTGACCCATCAAAATTGGGCGAGAAGCTAAAAGAAGTGACAGGTTGGTAGTATCAGTAGCTAACTGACTGTTAATAC
TCAAATGACGTTGAAAAATA

Downstream 100 bases:

>100_bases
GTATTATAGAAAACAAACCCTTATCCATTCTTATTAAGTATGTATTAATCCTTATGAAAAAAATTACTCACGCGGTGATA
CCCGTTGCAGGCTTTGGTAC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MKAPLQWGVFFCLKIALDINMENYKNKILVTGGAGYIGSHTCIALHEAGYEVVIYDNLSNSSFEAVNRVSSLIGQPIDFI
EGDIRDADSLRQVFVAHRFFGVIHFAGLKAVGESVAKPLMYYDNNVSGTITLLKIMAEYEVKKLVFSSSATVYGDPEILP
INEDSPRSCTNPYGQSKLTVEHVLEDLALSDNSWSLIPLRYFNPVGAHPSGQIGEDPNDIPNNLMPYISQVAVGKLDKLS
IFGDDYATVDGTGVRDFIHVTDLAQGHVAALNYLKQQKQSLGFLPINLGSGKGTSVLELVRAFSAVSAKDIPFQFVGRRA
GDIASCYASADKAQELLGWKASLSITDMCQDTWRWQSINPNGYNSI

Sequences:

>Translated_366_residues
MKAPLQWGVFFCLKIALDINMENYKNKILVTGGAGYIGSHTCIALHEAGYEVVIYDNLSNSSFEAVNRVSSLIGQPIDFI
EGDIRDADSLRQVFVAHRFFGVIHFAGLKAVGESVAKPLMYYDNNVSGTITLLKIMAEYEVKKLVFSSSATVYGDPEILP
INEDSPRSCTNPYGQSKLTVEHVLEDLALSDNSWSLIPLRYFNPVGAHPSGQIGEDPNDIPNNLMPYISQVAVGKLDKLS
IFGDDYATVDGTGVRDFIHVTDLAQGHVAALNYLKQQKQSLGFLPINLGSGKGTSVLELVRAFSAVSAKDIPFQFVGRRA
GDIASCYASADKAQELLGWKASLSITDMCQDTWRWQSINPNGYNSI
>Mature_366_residues
MKAPLQWGVFFCLKIALDINMENYKNKILVTGGAGYIGSHTCIALHEAGYEVVIYDNLSNSSFEAVNRVSSLIGQPIDFI
EGDIRDADSLRQVFVAHRFFGVIHFAGLKAVGESVAKPLMYYDNNVSGTITLLKIMAEYEVKKLVFSSSATVYGDPEILP
INEDSPRSCTNPYGQSKLTVEHVLEDLALSDNSWSLIPLRYFNPVGAHPSGQIGEDPNDIPNNLMPYISQVAVGKLDKLS
IFGDDYATVDGTGVRDFIHVTDLAQGHVAALNYLKQQKQSLGFLPINLGSGKGTSVLELVRAFSAVSAKDIPFQFVGRRA
GDIASCYASADKAQELLGWKASLSITDMCQDTWRWQSINPNGYNSI

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=346, Percent_Identity=55.7803468208092, Blast_Score=397, Evalue=1e-110,
Organism=Homo sapiens, GI56118217, Length=346, Percent_Identity=55.7803468208092, Blast_Score=397, Evalue=1e-110,
Organism=Homo sapiens, GI189083684, Length=346, Percent_Identity=55.7803468208092, Blast_Score=397, Evalue=1e-110,
Organism=Homo sapiens, GI7657641, Length=354, Percent_Identity=25.7062146892655, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1786974, Length=338, Percent_Identity=52.9585798816568, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI48994969, Length=366, Percent_Identity=25.1366120218579, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788353, Length=360, Percent_Identity=25.8333333333333, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=346, Percent_Identity=50, Blast_Score=347, Evalue=8e-96,
Organism=Caenorhabditis elegans, GI71982038, Length=348, Percent_Identity=49.7126436781609, Blast_Score=345, Evalue=2e-95,
Organism=Caenorhabditis elegans, GI17539532, Length=283, Percent_Identity=27.5618374558304, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=342, Percent_Identity=53.5087719298246, Blast_Score=376, Evalue=1e-105,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=54.2274052478134, Blast_Score=386, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 40058; Mature: 40058

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAPLQWGVFFCLKIALDINMENYKNKILVTGGAGYIGSHTCIALHEAGYEVVIYDNLSN
CCCCHHHHHHHHHHHHHCCCHHCCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCC
SSFEAVNRVSSLIGQPIDFIEGDIRDADSLRQVFVAHRFFGVIHFAGLKAVGESVAKPLM
CHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
YYDNNVSGTITLLKIMAEYEVKKLVFSSSATVYGDPEILPINEDSPRSCTNPYGQSKLTV
EECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEECCCCCCCCCCCCCCCCCEEH
EHVLEDLALSDNSWSLIPLRYFNPVGAHPSGQIGEDPNDIPNNLMPYISQVAVGKLDKLS
HHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEE
IFGDDYATVDGTGVRDFIHVTDLAQGHVAALNYLKQQKQSLGFLPINLGSGKGTSVLELV
EECCCCEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHH
RAFSAVSAKDIPFQFVGRRAGDIASCYASADKAQELLGWKASLSITDMCQDTWRWQSINP
HHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCC
NGYNSI
CCCCCC
>Mature Secondary Structure
MKAPLQWGVFFCLKIALDINMENYKNKILVTGGAGYIGSHTCIALHEAGYEVVIYDNLSN
CCCCHHHHHHHHHHHHHCCCHHCCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCC
SSFEAVNRVSSLIGQPIDFIEGDIRDADSLRQVFVAHRFFGVIHFAGLKAVGESVAKPLM
CHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
YYDNNVSGTITLLKIMAEYEVKKLVFSSSATVYGDPEILPINEDSPRSCTNPYGQSKLTV
EECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEECCCCCCCCCCCCCCCCCEEH
EHVLEDLALSDNSWSLIPLRYFNPVGAHPSGQIGEDPNDIPNNLMPYISQVAVGKLDKLS
HHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEE
IFGDDYATVDGTGVRDFIHVTDLAQGHVAALNYLKQQKQSLGFLPINLGSGKGTSVLELV
EECCCCEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHH
RAFSAVSAKDIPFQFVGRRAGDIASCYASADKAQELLGWKASLSITDMCQDTWRWQSINP
HHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCC
NGYNSI
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]