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The map label for this gene is lytS [H]

Identifier: 93004927

GI number: 93004927

Start: 111371

End: 112522

Strand: Direct

Name: lytS [H]

Synonym: Pcryo_0096

Alternate gene names: 93004927

Gene position: 111371-112522 (Clockwise)

Preceding gene: 93004923

Following gene: 93004928

Centisome position: 3.64

GC content: 40.02

Gene sequence:

>1152_bases
TTGAAGAATTGGCGTTCATATCAGTCTAAGACAAGTCAAGAGAATAAGAACTCAAGTATAGCAAATGATGAGGTTGCCTT
ACTAGCGGAGCGCTTAGAGTTTTTTATACCCAAGCTCATGGAAATCATGAAACCTTGGCAATGGCTGCTGGTAATCTTTT
TTTGGTCGCTTTTTTTAGCGATTGTCGATCGTCATAGCGTTGTCAATGAAACACAATTTGCCATAAAAATGACAGCAAGA
TTTATCCAAACCACCTTAACACTACTGCCTTCCTTTTATCTCATTGACTATCTACGCCCTGTTTTTAAACGTATGCGTAC
ATTGAAGGTGAGCTTATATGTTCTGTTTATCATCACTATCAGTGCCATTATCACGTTGATACTGGTTCTGTTATTGATGA
TCAATACAGGCGCCTTTACCTTTACTCTCACTGCTTTTATTTCAACCGTTATCTTTAACACTTTAATTATTGCAGGATTT
ACCATTACAGGATTGCTGATCTTTTTACGTCGTTATCGTGAGATGACGGCGTTGAAGCAATCGTTTGAAAAAAAGCTTGC
CGCACAAAATGATGTATTAAAAGCGCGTCTGGCACCGCATTTCTTTTTTAATACCATTAATACCTTGATGTCACTGATTG
AGACCAATCCTTCTCGCGCTGCCGATTTATTACAACACGTTTCAGTATTATTTCGTGCCAGCTTTAATGGTGCGCGCGAG
ATCAGTTTTGCAGAAGAGGTGGCACTTTGTGAGCATTATTTGGCCATTGAGACGATTCGATTGGCAGACAAGTTGGTAGT
AAGTTGGCAGCTGCCTGATGAAAATATCATGTATGACATGGTCATCACCGCTTTAAGTTTACAGAGCGTGATTGAAAAAA
TGCTGCTGAATGTGGTTGAGAGGAGCACTGAGACTGTATATATCGATATTCATGTCACGTGGCTACAGCACCGTGTGGCA
ATCACCATTAACGTGCAATTACCTAAAAATAGTTTAATGATCCATCATGATTTGCGCCAGCATATGGATTTTCATATTCA
AGCGCAGCGCTTACAAGCGTATTTTGGTCAGAGTGCAGATATCCAAAGTAGGGTGACAAGCAAACAGATTATGACCACTA
TCGATTATCCGCTACAGGACGTTAGCTTATAG

Upstream 100 bases:

>100_bases
CTAGTAGTAGGGCTGTTCTGTGCGGCAGCGTTTGTTATAGAAGCATCTGTGCTAAACTCAGAAGCAGATGAATTTTTATT
TGAATCAGGATTACTAAGGT

Downstream 100 bases:

>100_bases
CTTTTTTAACCGTGGCATATTTATTGCAGCATTTATTATATCGTACGAATAGTAGGGACAGATGATAAGTCTGATTAAGG
TAAATCTATTATCAAAAACC

Product: histidine kinase

Products: NA

Alternate protein names: Autolysin sensor kinase [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MKNWRSYQSKTSQENKNSSIANDEVALLAERLEFFIPKLMEIMKPWQWLLVIFFWSLFLAIVDRHSVVNETQFAIKMTAR
FIQTTLTLLPSFYLIDYLRPVFKRMRTLKVSLYVLFIITISAIITLILVLLLMINTGAFTFTLTAFISTVIFNTLIIAGF
TITGLLIFLRRYREMTALKQSFEKKLAAQNDVLKARLAPHFFFNTINTLMSLIETNPSRAADLLQHVSVLFRASFNGARE
ISFAEEVALCEHYLAIETIRLADKLVVSWQLPDENIMYDMVITALSLQSVIEKMLLNVVERSTETVYIDIHVTWLQHRVA
ITINVQLPKNSLMIHHDLRQHMDFHIQAQRLQAYFGQSADIQSRVTSKQIMTTIDYPLQDVSL

Sequences:

>Translated_383_residues
MKNWRSYQSKTSQENKNSSIANDEVALLAERLEFFIPKLMEIMKPWQWLLVIFFWSLFLAIVDRHSVVNETQFAIKMTAR
FIQTTLTLLPSFYLIDYLRPVFKRMRTLKVSLYVLFIITISAIITLILVLLLMINTGAFTFTLTAFISTVIFNTLIIAGF
TITGLLIFLRRYREMTALKQSFEKKLAAQNDVLKARLAPHFFFNTINTLMSLIETNPSRAADLLQHVSVLFRASFNGARE
ISFAEEVALCEHYLAIETIRLADKLVVSWQLPDENIMYDMVITALSLQSVIEKMLLNVVERSTETVYIDIHVTWLQHRVA
ITINVQLPKNSLMIHHDLRQHMDFHIQAQRLQAYFGQSADIQSRVTSKQIMTTIDYPLQDVSL
>Mature_383_residues
MKNWRSYQSKTSQENKNSSIANDEVALLAERLEFFIPKLMEIMKPWQWLLVIFFWSLFLAIVDRHSVVNETQFAIKMTAR
FIQTTLTLLPSFYLIDYLRPVFKRMRTLKVSLYVLFIITISAIITLILVLLLMINTGAFTFTLTAFISTVIFNTLIIAGF
TITGLLIFLRRYREMTALKQSFEKKLAAQNDVLKARLAPHFFFNTINTLMSLIETNPSRAADLLQHVSVLFRASFNGARE
ISFAEEVALCEHYLAIETIRLADKLVVSWQLPDENIMYDMVITALSLQSVIEKMLLNVVERSTETVYIDIHVTWLQHRVA
ITINVQLPKNSLMIHHDLRQHMDFHIQAQRLQAYFGQSADIQSRVTSKQIMTTIDYPLQDVSL

Specific function: Member of the two-component regulatory system lytR/lytS that probably regulates genes involved in cell wall metabolism [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44352; Mature: 44352

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNWRSYQSKTSQENKNSSIANDEVALLAERLEFFIPKLMEIMKPWQWLLVIFFWSLFLA
CCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVDRHSVVNETQFAIKMTARFIQTTLTLLPSFYLIDYLRPVFKRMRTLKVSLYVLFIITI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAIITLILVLLLMINTGAFTFTLTAFISTVIFNTLIIAGFTITGLLIFLRRYREMTALKQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFEKKLAAQNDVLKARLAPHFFFNTINTLMSLIETNPSRAADLLQHVSVLFRASFNGARE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCC
ISFAEEVALCEHYLAIETIRLADKLVVSWQLPDENIMYDMVITALSLQSVIEKMLLNVVE
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RSTETVYIDIHVTWLQHRVAITINVQLPKNSLMIHHDLRQHMDFHIQAQRLQAYFGQSAD
CCCCEEEEEEEEEEEEEEEEEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCC
IQSRVTSKQIMTTIDYPLQDVSL
HHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKNWRSYQSKTSQENKNSSIANDEVALLAERLEFFIPKLMEIMKPWQWLLVIFFWSLFLA
CCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVDRHSVVNETQFAIKMTARFIQTTLTLLPSFYLIDYLRPVFKRMRTLKVSLYVLFIITI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAIITLILVLLLMINTGAFTFTLTAFISTVIFNTLIIAGFTITGLLIFLRRYREMTALKQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFEKKLAAQNDVLKARLAPHFFFNTINTLMSLIETNPSRAADLLQHVSVLFRASFNGARE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCC
ISFAEEVALCEHYLAIETIRLADKLVVSWQLPDENIMYDMVITALSLQSVIEKMLLNVVE
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RSTETVYIDIHVTWLQHRVAITINVQLPKNSLMIHHDLRQHMDFHIQAQRLQAYFGQSAD
CCCCEEEEEEEEEEEEEEEEEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCC
IQSRVTSKQIMTTIDYPLQDVSL
HHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA