Click here to switch to the map view.

The map label for this gene is algR [H]

Identifier: 93004928

GI number: 93004928

Start: 112718

End: 113455

Strand: Direct

Name: algR [H]

Synonym: Pcryo_0097

Alternate gene names: 93004928

Gene position: 112718-113455 (Clockwise)

Preceding gene: 93004927

Following gene: 93004929

Centisome position: 3.68

GC content: 44.85

Gene sequence:

>738_bases
ATGCGGATCGTAGTTTGTGATGATGAACCATTAGCTCGTGAACGTTTGGTTAGGATTGTTAAAGAGTCAGGTCATGAGGT
GGTTGCCCAAGCAAAGACGGGTATCGAAGCCATTAGTGCCGTAAAATCTCAGCAGCCAGACATCATATTGCTAGATATTC
GTATGCCTGAGATGGATGGCGTACAGTGTGCGCAAGAGCTTGCTAAGCTGCAACATCCGCCCGCAATCATCTTTGTGACG
GCCTATGATCATTATGCCATTGCCGCTCTAAAAGCCAATGCTATTGGTTACTTGCTAAAGCCTGCCAATAAAGATGAGTT
GCTCGAAGCCCTAGAAAAAGCCACCAATCTCAATGCGGCGCAGCTCAATGAGATTCGTAAACTTGAAAGTCCAACGTCTC
GTCCAGTGCGCGAACATATTGCAGCGCGTACCCATCGCGGTGTTGAGCTGATAAAACTCAAAGACATCTACTATTTTACG
GCAGATCAGAAGTACGTCAAAGTACGGCACAAGGATGGCATCGTGCTCATTGATGACACCTTAAAAGAGCTTGAGCAAGA
GTTTGAAGACAAGCTGTTCCGGGTACATCGTAACGCTATCATCAATATCAAATATTTAGATTTTTTAGAGACTTTAGATG
CCGGCCAATATCAGCTACATTTTAAAGGAATTGATGAGACTTTAGCAGTGAGCCGCCGCCATTTACCAGGGCTGCGCGAA
AAGATTCAAAACATTTAA

Upstream 100 bases:

>100_bases
AAACCATTATTTCCCTATACTAAATGATAGGTTATAAGTGCTAATATATTATTGATATTTTTAAATATATGTTCAAAGTA
TGCCCTTGAAAGGAGCTTGC

Downstream 100 bases:

>100_bases
GCATGCCTCACTTTGTCTCCTAAAATAATCACGCCATATCATCAAACCCTTATTTATGCTTAAATAGGGGTATTTTTTTT
GCATTATTATCGTTATAAAC

Product: LytR/AlgR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MRIVVCDDEPLARERLVRIVKESGHEVVAQAKTGIEAISAVKSQQPDIILLDIRMPEMDGVQCAQELAKLQHPPAIIFVT
AYDHYAIAALKANAIGYLLKPANKDELLEALEKATNLNAAQLNEIRKLESPTSRPVREHIAARTHRGVELIKLKDIYYFT
ADQKYVKVRHKDGIVLIDDTLKELEQEFEDKLFRVHRNAIINIKYLDFLETLDAGQYQLHFKGIDETLAVSRRHLPGLRE
KIQNI

Sequences:

>Translated_245_residues
MRIVVCDDEPLARERLVRIVKESGHEVVAQAKTGIEAISAVKSQQPDIILLDIRMPEMDGVQCAQELAKLQHPPAIIFVT
AYDHYAIAALKANAIGYLLKPANKDELLEALEKATNLNAAQLNEIRKLESPTSRPVREHIAARTHRGVELIKLKDIYYFT
ADQKYVKVRHKDGIVLIDDTLKELEQEFEDKLFRVHRNAIINIKYLDFLETLDAGQYQLHFKGIDETLAVSRRHLPGLRE
KIQNI
>Mature_245_residues
MRIVVCDDEPLARERLVRIVKESGHEVVAQAKTGIEAISAVKSQQPDIILLDIRMPEMDGVQCAQELAKLQHPPAIIFVT
AYDHYAIAALKANAIGYLLKPANKDELLEALEKATNLNAAQLNEIRKLESPTSRPVREHIAARTHRGVELIKLKDIYYFT
ADQKYVKVRHKDGIVLIDDTLKELEQEFEDKLFRVHRNAIINIKYLDFLETLDAGQYQLHFKGIDETLAVSRRHLPGLRE
KIQNI

Specific function: Positive regulator of the algD gene, which codes for a GDP-mannose dehydrogenase, a key step enzyme in the alginate biosynthesis pathway [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=244, Percent_Identity=32.3770491803279, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1788724, Length=250, Percent_Identity=28.8, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788550, Length=134, Percent_Identity=34.3283582089552, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=36.8421052631579, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788905, Length=124, Percent_Identity=30.6451612903226, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788712, Length=118, Percent_Identity=30.5084745762712, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 27933; Mature: 27933

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVVCDDEPLARERLVRIVKESGHEVVAQAKTGIEAISAVKSQQPDIILLDIRMPEMDG
CEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCH
VQCAQELAKLQHPPAIIFVTAYDHYAIAALKANAIGYLLKPANKDELLEALEKATNLNAA
HHHHHHHHHHCCCCEEEEEEECCCEEEEEEHHHHHEEEECCCCHHHHHHHHHHHCCCCHH
QLNEIRKLESPTSRPVREHIAARTHRGVELIKLKDIYYFTADQKYVKVRHKDGIVLIDDT
HHHHHHHHCCCCCCHHHHHHHHHHHCCEEEEEEEEEEEEECCCEEEEEEECCCEEEEHHH
LKELEQEFEDKLFRVHRNAIINIKYLDFLETLDAGQYQLHFKGIDETLAVSRRHLPGLRE
HHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCHHHH
KIQNI
HHHCC
>Mature Secondary Structure
MRIVVCDDEPLARERLVRIVKESGHEVVAQAKTGIEAISAVKSQQPDIILLDIRMPEMDG
CEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCH
VQCAQELAKLQHPPAIIFVTAYDHYAIAALKANAIGYLLKPANKDELLEALEKATNLNAA
HHHHHHHHHHCCCCEEEEEEECCCEEEEEEHHHHHEEEECCCCHHHHHHHHHHHCCCCHH
QLNEIRKLESPTSRPVREHIAARTHRGVELIKLKDIYYFTADQKYVKVRHKDGIVLIDDT
HHHHHHHHCCCCCCHHHHHHHHHHHCCEEEEEEEEEEEEECCCEEEEEEECCCEEEEHHH
LKELEQEFEDKLFRVHRNAIINIKYLDFLETLDAGQYQLHFKGIDETLAVSRRHLPGLRE
HHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCHHHH
KIQNI
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2493441; 10984043; 2544550; 8159168 [H]