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The map label for this gene is ectC

Identifier: 92114001

GI number: 92114001

Start: 2136280

End: 2136672

Strand: Direct

Name: ectC

Synonym: Csal_1878

Alternate gene names: 92114001

Gene position: 2136280-2136672 (Clockwise)

Preceding gene: 92114000

Following gene: 92114002

Centisome position: 57.79

GC content: 58.02

Gene sequence:

>393_bases
ATGATCGTTCGTAACCTGGAAGAATGCCGCAAGACCGAGCGCTTCGTCGAAGCCGAAAACGGCAACTGGGACAGCACCCG
TCTGGTGCTGGCCGACGACAACGTCGGTTTCTCGTTCAACATCACCCGCATTCATCCGGGTACCGAGACGCATATCCATT
ACAAGCATCACTTCGAGGCGGTTTTCTGCTACGAAGGCGAAGGCGAAGTCGAAACGCTGGCCGATGGCAAGATCCATCCC
ATCAAGGCCGGCGACATGTACTTGCTCGATCAGCACGACGAGCACCTGCTGCGCGGCAAGGAAAAAGGCATGACCGTGGC
ATGCGTGTTCAATCCGGCGCTGACGGGCCGCGAAGTGCACCGTGAAGACGGTTCCTACGCACCGGTCGATTGA

Upstream 100 bases:

>100_bases
AGTCCACTAAATTGTCATTCGCAAATGTGTTTACAGTGGGCACCGCCTGCGGCCACGAGGTCGCGGGCTTCTTACTCAGA
TCTGCAGAGGATTGCGCCAC

Downstream 100 bases:

>100_bases
ACCTTCAGTTGAACTGTACCCGAGAAAGCGCTGCCGAATGGCAGCGCTTTCTTTTGAGGTTTCGTGCGCGTCGGGATCGT
CAGACATGTCCCGCACGAGT

Product: L-ectoine synthase

Products: NA

Alternate protein names: N-acetyldiaminobutyrate dehydratase

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MIVRNLEECRKTERFVEAENGNWDSTRLVLADDNVGFSFNITRIHPGTETHIHYKHHFEAVFCYEGEGEVETLADGKIHP
IKAGDMYLLDQHDEHLLRGKEKGMTVACVFNPALTGREVHREDGSYAPVD

Sequences:

>Translated_130_residues
MIVRNLEECRKTERFVEAENGNWDSTRLVLADDNVGFSFNITRIHPGTETHIHYKHHFEAVFCYEGEGEVETLADGKIHP
IKAGDMYLLDQHDEHLLRGKEKGMTVACVFNPALTGREVHREDGSYAPVD
>Mature_130_residues
MIVRNLEECRKTERFVEAENGNWDSTRLVLADDNVGFSFNITRIHPGTETHIHYKHHFEAVFCYEGEGEVETLADGKIHP
IKAGDMYLLDQHDEHLLRGKEKGMTVACVFNPALTGREVHREDGSYAPVD

Specific function: Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ectoine synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ECTC_CHRSD (Q9ZEU6)

Other databases:

- EMBL:   AJ011103
- EMBL:   CP000285
- RefSeq:   YP_573929.1
- ProteinModelPortal:   Q9ZEU6
- STRING:   Q9ZEU6
- GeneID:   4028241
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_1878
- NMPDR:   fig|290398.4.peg.1992
- eggNOG:   NOG08290
- HOGENOM:   HBG294526
- OMA:   DENGVYP
- ProtClustDB:   PRK13290
- BioCyc:   CSAL290398:CSAL_1878-MONOMER
- BioCyc:   MetaCyc:MONOMER-803
- BRENDA:   4.2.1.108
- HAMAP:   MF_01255
- InterPro:   IPR011051
- InterPro:   IPR010462
- InterPro:   IPR014710
- Gene3D:   G3DSA:2.60.120.10
- ProDom:   PD080544

Pfam domain/function: PF06339 Ectoine_synth; SSF51182 RmlC_like_cupin

EC number: =4.2.1.108

Molecular weight: Translated: 14825; Mature: 14825

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVRNLEECRKTERFVEAENGNWDSTRLVLADDNVGFSFNITRIHPGTETHIHYKHHFEA
CCCCCHHHHHHHHHEEECCCCCCCCEEEEEEECCCCEEEEEEEECCCCCEEEEEEECEEE
VFCYEGEGEVETLADGKIHPIKAGDMYLLDQHDEHLLRGKEKGMTVACVFNPALTGREVH
EEEECCCCCEEEECCCCEEEEECCCEEEEECCCCHHHCCCCCCCEEEEEECCCCCCCEEE
REDGSYAPVD
CCCCCCCCCC
>Mature Secondary Structure
MIVRNLEECRKTERFVEAENGNWDSTRLVLADDNVGFSFNITRIHPGTETHIHYKHHFEA
CCCCCHHHHHHHHHEEECCCCCCCCEEEEEEECCCCEEEEEEEECCCCCEEEEEEECEEE
VFCYEGEGEVETLADGKIHPIKAGDMYLLDQHDEHLLRGKEKGMTVACVFNPALTGREVH
EEEECCCCCEEEECCCCEEEEECCCEEEEECCCCHHHCCCCCCCEEEEEECCCCCCCEEE
REDGSYAPVD
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9924816