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The map label for this gene is ectB

Identifier: 92114000

GI number: 92114000

Start: 2134894

End: 2136165

Strand: Direct

Name: ectB

Synonym: Csal_1877

Alternate gene names: 92114000

Gene position: 2134894-2136165 (Clockwise)

Preceding gene: 92113999

Following gene: 92114001

Centisome position: 57.75

GC content: 61.87

Gene sequence:

>1272_bases
ATGCAGACCCAGATTCTCGAACGCATGGAATCCGAAGTCCGGACCTATTCACGTTCTTTTCCTACCGTTTTCACTGAAGC
CAAGGGCGCGCGCCTGCATGCCGAGGACGGCAACCAGTACATCGATTTTCTCGCCGGCGCCGGCACGCTCAACTACGGTC
ACAACCACCCCAAGCTCAAGCAGGCACTGGCCGATTACATCGCCTCCGATGGCATCGTCCATGGTCTGGACATGTGGAGC
GCGGCCAAGCGCGACTATCTGGAAACCCTCGAAGAGGTGATCCTCAAGCCGCGTGGCCTGGATTACAAGGTTCATCTGCC
GGGCCCGACGGGCACCAATGCCGTGGAAGCCGCCATTCGACTGGCGCGCAACGCCAAGGGTCGTCACAACATCGTCACCT
TCACCAACGGATTCCATGGCGTGACCATGGGCGCGCTGGCCACCACCGGCAATCGCAAGTTCCGTGAAGCCACCGGCGGT
ATCCCGACCCAGGGCGCCAGCTTCATGCCGTTCGATGGCTACATGGGCGAGGGCGTCGACACCCTGAGCTACTTCGAGAA
ACTGCTCGGCGACAACTCCGGTGGTCTCGACGTTCCCGCGGCCGTGATCATCGAGACGGTGCAGGGCGAGGGCGGTATCA
ATCCGGCCGGCATCCCGTGGCTGCAGCGCCTGGAAAAGATCTGCCGCGATCACGACATGCTGCTGATCGTCGACGACATT
CAGGCCGGCTGCGGTCGTACGGGCAAGTTCTTCAGCTTCGAGCATGCCGGCATCACGCCGGACATCGTCACCAACTCCAA
GTCCCTGTCGGGTTTCGGCCTGCCGTTCGCGCATGTGCTGATGCGCCCGGAACTGGATATCTGGAAGCCCGGCCAGTACA
ACGGCACGTTCCGTGGTTTCAACCTGGCCTTCGTCACGGCCGCCGCCGCGATGCGTCACTTCTGGAGCGACGACACCTTC
GAGCGCGACGTTCAGCGCAAGGGCCGTGTGGTCGAGGATCGCTTCCAGAAGCTTGCCAGCTTCATGACCGAGAAAGGGCA
TCCGGCCAGCGAGCGTGGCCGTGGCCTGATGCGTGGCCTGGACGTCGGTGACGGCGACATGGCCGACAAGATCACCGCAC
AAGCGTTCAAGAACGGGCTGATCATCGAGACATCCGGCCATTCAGGCCAGGTGATCAAGTGCCTTTGCCCGTTGACCATT
ACCGACGAAGACCTCGTCGGCGGCCTGGACATCCTCGAGCAGAGCGTCAAGGAAGTCTTCGGTCAAGCCTAA

Upstream 100 bases:

>100_bases
CTCCACGGGGCAGTTGGGTGGCGAGCACGATCCGGAAAATCTCGTCCGTATCGGCCCGTTCGAGCCGCAACAAATTTGAT
CCGTCAATCAGAGGCAATCT

Downstream 100 bases:

>100_bases
GTCCATTGTTCGTTAGTCCACTAAATTGTCATTCGCAAATGTGTTTACAGTGGGCACCGCCTGCGGCCACGAGGTCGCGG
GCTTCTTACTCAGATCTGCA

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: DABA aminotransferase; Diaminobutyrate--2-oxoglutarate aminotransferase; L-2,4-diaminobutyric acid transaminase

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MQTQILERMESEVRTYSRSFPTVFTEAKGARLHAEDGNQYIDFLAGAGTLNYGHNHPKLKQALADYIASDGIVHGLDMWS
AAKRDYLETLEEVILKPRGLDYKVHLPGPTGTNAVEAAIRLARNAKGRHNIVTFTNGFHGVTMGALATTGNRKFREATGG
IPTQGASFMPFDGYMGEGVDTLSYFEKLLGDNSGGLDVPAAVIIETVQGEGGINPAGIPWLQRLEKICRDHDMLLIVDDI
QAGCGRTGKFFSFEHAGITPDIVTNSKSLSGFGLPFAHVLMRPELDIWKPGQYNGTFRGFNLAFVTAAAAMRHFWSDDTF
ERDVQRKGRVVEDRFQKLASFMTEKGHPASERGRGLMRGLDVGDGDMADKITAQAFKNGLIIETSGHSGQVIKCLCPLTI
TDEDLVGGLDILEQSVKEVFGQA

Sequences:

>Translated_423_residues
MQTQILERMESEVRTYSRSFPTVFTEAKGARLHAEDGNQYIDFLAGAGTLNYGHNHPKLKQALADYIASDGIVHGLDMWS
AAKRDYLETLEEVILKPRGLDYKVHLPGPTGTNAVEAAIRLARNAKGRHNIVTFTNGFHGVTMGALATTGNRKFREATGG
IPTQGASFMPFDGYMGEGVDTLSYFEKLLGDNSGGLDVPAAVIIETVQGEGGINPAGIPWLQRLEKICRDHDMLLIVDDI
QAGCGRTGKFFSFEHAGITPDIVTNSKSLSGFGLPFAHVLMRPELDIWKPGQYNGTFRGFNLAFVTAAAAMRHFWSDDTF
ERDVQRKGRVVEDRFQKLASFMTEKGHPASERGRGLMRGLDVGDGDMADKITAQAFKNGLIIETSGHSGQVIKCLCPLTI
TDEDLVGGLDILEQSVKEVFGQA
>Mature_423_residues
MQTQILERMESEVRTYSRSFPTVFTEAKGARLHAEDGNQYIDFLAGAGTLNYGHNHPKLKQALADYIASDGIVHGLDMWS
AAKRDYLETLEEVILKPRGLDYKVHLPGPTGTNAVEAAIRLARNAKGRHNIVTFTNGFHGVTMGALATTGNRKFREATGG
IPTQGASFMPFDGYMGEGVDTLSYFEKLLGDNSGGLDVPAAVIIETVQGEGGINPAGIPWLQRLEKICRDHDMLLIVDDI
QAGCGRTGKFFSFEHAGITPDIVTNSKSLSGFGLPFAHVLMRPELDIWKPGQYNGTFRGFNLAFVTAAAAMRHFWSDDTF
ERDVQRKGRVVEDRFQKLASFMTEKGHPASERGRGLMRGLDVGDGDMADKITAQAFKNGLIIETSGHSGQVIKCLCPLTI
TDEDLVGGLDILEQSVKEVFGQA

Specific function: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family

Homologues:

Organism=Homo sapiens, GI4557809, Length=410, Percent_Identity=27.5609756097561, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI284507298, Length=319, Percent_Identity=26.3322884012539, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI188536080, Length=317, Percent_Identity=25.2365930599369, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI38679950, Length=317, Percent_Identity=25.2365930599369, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI38679946, Length=317, Percent_Identity=25.2365930599369, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI1789016, Length=424, Percent_Identity=31.1320754716981, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1787560, Length=406, Percent_Identity=32.0197044334975, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1788044, Length=402, Percent_Identity=29.1044776119403, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI145693181, Length=376, Percent_Identity=27.6595744680851, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789759, Length=410, Percent_Identity=28.2926829268293, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1786991, Length=261, Percent_Identity=34.0996168582375, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25144271, Length=430, Percent_Identity=26.7441860465116, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI32564660, Length=436, Percent_Identity=27.0642201834862, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25144274, Length=300, Percent_Identity=26, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17541228, Length=454, Percent_Identity=24.4493392070485, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324432, Length=430, Percent_Identity=29.7674418604651, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6323470, Length=416, Percent_Identity=29.0865384615385, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6321456, Length=429, Percent_Identity=23.7762237762238, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324386, Length=438, Percent_Identity=24.6575342465753, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21357415, Length=406, Percent_Identity=25.8620689655172, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI161085790, Length=434, Percent_Identity=26.7281105990783, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI28574759, Length=437, Percent_Identity=26.0869565217391, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281366494, Length=415, Percent_Identity=23.6144578313253, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24667139, Length=415, Percent_Identity=23.6144578313253, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24667143, Length=415, Percent_Identity=23.6144578313253, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ECTB_CHRSD (Q9ZEU7)

Other databases:

- EMBL:   AJ011103
- EMBL:   CP000285
- RefSeq:   YP_573928.1
- ProteinModelPortal:   Q9ZEU7
- STRING:   Q9ZEU7
- GeneID:   4028240
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_1877
- NMPDR:   fig|290398.4.peg.1991
- eggNOG:   COG0160
- HOGENOM:   HBG725944
- OMA:   VISFTNG
- ProtClustDB:   PRK09264
- BioCyc:   CSAL290398:CSAL_1877-MONOMER
- BioCyc:   MetaCyc:MONOMER-801
- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR012773
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PANTHER:   PTHR11986
- PANTHER:   PTHR11986:SF7
- TIGRFAMs:   TIGR00709
- TIGRFAMs:   TIGR02407

Pfam domain/function: PF00202 Aminotran_3; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.76

Molecular weight: Translated: 46201; Mature: 46201

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTQILERMESEVRTYSRSFPTVFTEAKGARLHAEDGNQYIDFLAGAGTLNYGHNHPKLK
CCHHHHHHHHHHHHHHHHCCCCCEECCCCCEEECCCCCHHHHHHHCCCCCCCCCCCHHHH
QALADYIASDGIVHGLDMWSAAKRDYLETLEEVILKPRGLDYKVHLPGPTGTNAVEAAIR
HHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHH
LARNAKGRHNIVTFTNGFHGVTMGALATTGNRKFREATGGIPTQGASFMPFDGYMGEGVD
HHHCCCCCCCEEEEECCCCCHHHHHEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCH
TLSYFEKLLGDNSGGLDVPAAVIIETVQGEGGINPAGIPWLQRLEKICRDHDMLLIVDDI
HHHHHHHHHCCCCCCCCCCHHHHEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECC
QAGCGRTGKFFSFEHAGITPDIVTNSKSLSGFGLPFAHVLMRPELDIWKPGQYNGTFRGF
CCCCCCCCCEEEEECCCCCHHHEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCC
NLAFVTAAAAMRHFWSDDTFERDVQRKGRVVEDRFQKLASFMTEKGHPASERGRGLMRGL
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHCCHHHHCC
DVGDGDMADKITAQAFKNGLIIETSGHSGQVIKCLCPLTITDEDLVGGLDILEQSVKEVF
CCCCCCHHHHHHHHHHHCCEEEEECCCCCCEEEEEECCEECCHHHHCHHHHHHHHHHHHH
GQA
CCC
>Mature Secondary Structure
MQTQILERMESEVRTYSRSFPTVFTEAKGARLHAEDGNQYIDFLAGAGTLNYGHNHPKLK
CCHHHHHHHHHHHHHHHHCCCCCEECCCCCEEECCCCCHHHHHHHCCCCCCCCCCCHHHH
QALADYIASDGIVHGLDMWSAAKRDYLETLEEVILKPRGLDYKVHLPGPTGTNAVEAAIR
HHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHH
LARNAKGRHNIVTFTNGFHGVTMGALATTGNRKFREATGGIPTQGASFMPFDGYMGEGVD
HHHCCCCCCCEEEEECCCCCHHHHHEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCH
TLSYFEKLLGDNSGGLDVPAAVIIETVQGEGGINPAGIPWLQRLEKICRDHDMLLIVDDI
HHHHHHHHHCCCCCCCCCCHHHHEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECC
QAGCGRTGKFFSFEHAGITPDIVTNSKSLSGFGLPFAHVLMRPELDIWKPGQYNGTFRGF
CCCCCCCCCEEEEECCCCCHHHEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCC
NLAFVTAAAAMRHFWSDDTFERDVQRKGRVVEDRFQKLASFMTEKGHPASERGRGLMRGL
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHCCHHHHCC
DVGDGDMADKITAQAFKNGLIIETSGHSGQVIKCLCPLTITDEDLVGGLDILEQSVKEVF
CCCCCCHHHHHHHHHHHCCEEEEECCCCCCEEEEEECCEECCHHHHCHHHHHHHHHHHHH
GQA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9924816