Click here to switch to the map view.

The map label for this gene is tolQ [H]

Identifier: 92113973

GI number: 92113973

Start: 2105457

End: 2106134

Strand: Direct

Name: tolQ [H]

Synonym: Csal_1850

Alternate gene names: 92113973

Gene position: 2105457-2106134 (Clockwise)

Preceding gene: 92113972

Following gene: 92113974

Centisome position: 56.96

GC content: 61.95

Gene sequence:

>678_bases
ATGTCCATCCCGCATCTGATCATGAACGCCAGCCTGGTCGTTCAGTTGGTCATGCTTCTTCTGCTGGCGGCTTCCGTCGC
CTCCTGGATCGTGATTTTCCAGCGCGGCTTCGCCCTGCGGCGTGCCGAAAAGGCCTATCGGGACTTCGAGGATCGCTTCT
GGTCCGGCGTGGATCTCAATGAACTCTATCGCGAACTGCCCGCCGAGCAGGAATCGCTCGGCGCGGAACACGTCTTCCGC
TCCGGTTTCCGCGAGTTCAACCGCCTGATGGCCAAGACCCAGAGTACCGAGGCGGTTCTCGAAGGGGTGCAGCGCGGTCA
ACGGGTCGCGCTGTCCCGCGAAGAAGATCGTCTGCAGCTGCATCTGACCTTCCTGGCTACCGTGGCCTCGGCCACCCCCT
ACATCGGTCTTTTCGGTACCGTATGGGGCATCATGGGCTCGTTCCAGAGCCTGTCCATGGCCCAGCAGGCCACGCTTTCC
ACGGTCGCGCCATGGATTGCGGAAGCGCTGGTAGCCACGGCCATGGGGCTGTTCGCCGCGATCCCCGCCGTGATTTTCTA
CAACCGGCTTTCTGCCCATGCGACGAGGCTTCTCGGCAAATACGAAAACTTCGCCGAGGAATTCCACGCCATCCTGCATC
GAAACCTGCAGGGACGCAGCGAACGCGCGGCATCCTGA

Upstream 100 bases:

>100_bases
AAAACCCGTGCGTTGGCCGGATGCCCTGCATTCCGTCATGCTCGGATAACCAAGCGAAACGAACTCTCAAAGCGACACGA
GGACTGCCGTGAACGACTCC

Downstream 100 bases:

>100_bases
GGGAGGAAGCATGTACGGATCCTATCATCGCCGCCAGCGGCGCAAGCCCATGGGCGAAATCAATGTCGTGCCTTTCATCG
ACGTGATGCTGGTACTGCTG

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MSIPHLIMNASLVVQLVMLLLLAASVASWIVIFQRGFALRRAEKAYRDFEDRFWSGVDLNELYRELPAEQESLGAEHVFR
SGFREFNRLMAKTQSTEAVLEGVQRGQRVALSREEDRLQLHLTFLATVASATPYIGLFGTVWGIMGSFQSLSMAQQATLS
TVAPWIAEALVATAMGLFAAIPAVIFYNRLSAHATRLLGKYENFAEEFHAILHRNLQGRSERAAS

Sequences:

>Translated_225_residues
MSIPHLIMNASLVVQLVMLLLLAASVASWIVIFQRGFALRRAEKAYRDFEDRFWSGVDLNELYRELPAEQESLGAEHVFR
SGFREFNRLMAKTQSTEAVLEGVQRGQRVALSREEDRLQLHLTFLATVASATPYIGLFGTVWGIMGSFQSLSMAQQATLS
TVAPWIAEALVATAMGLFAAIPAVIFYNRLSAHATRLLGKYENFAEEFHAILHRNLQGRSERAAS
>Mature_224_residues
SIPHLIMNASLVVQLVMLLLLAASVASWIVIFQRGFALRRAEKAYRDFEDRFWSGVDLNELYRELPAEQESLGAEHVFRS
GFREFNRLMAKTQSTEAVLEGVQRGQRVALSREEDRLQLHLTFLATVASATPYIGLFGTVWGIMGSFQSLSMAQQATLST
VAPWIAEALVATAMGLFAAIPAVIFYNRLSAHATRLLGKYENFAEEFHAILHRNLQGRSERAAS

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=216, Percent_Identity=52.7777777777778, Blast_Score=219, Evalue=1e-58,
Organism=Escherichia coli, GI1789381, Length=209, Percent_Identity=33.4928229665072, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 25148; Mature: 25017

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIPHLIMNASLVVQLVMLLLLAASVASWIVIFQRGFALRRAEKAYRDFEDRFWSGVDLN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ELYRELPAEQESLGAEHVFRSGFREFNRLMAKTQSTEAVLEGVQRGQRVALSREEDRLQL
HHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
HLTFLATVASATPYIGLFGTVWGIMGSFQSLSMAQQATLSTVAPWIAEALVATAMGLFAA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPAVIFYNRLSAHATRLLGKYENFAEEFHAILHRNLQGRSERAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SIPHLIMNASLVVQLVMLLLLAASVASWIVIFQRGFALRRAEKAYRDFEDRFWSGVDLN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ELYRELPAEQESLGAEHVFRSGFREFNRLMAKTQSTEAVLEGVQRGQRVALSREEDRLQL
HHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
HLTFLATVASATPYIGLFGTVWGIMGSFQSLSMAQQATLSTVAPWIAEALVATAMGLFAA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPAVIFYNRLSAHATRLLGKYENFAEEFHAILHRNLQGRSERAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]