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The map label for this gene is uxuR [H]

Identifier: 92113862

GI number: 92113862

Start: 1982728

End: 1983483

Strand: Direct

Name: uxuR [H]

Synonym: Csal_1739

Alternate gene names: 92113862

Gene position: 1982728-1983483 (Clockwise)

Preceding gene: 92113853

Following gene: 92113866

Centisome position: 53.64

GC content: 66.14

Gene sequence:

>756_bases
ATGCCGATTCAAACCATTCGCTCACAGCGCCTGTACCGGCAGATCGCCGATCAGTTGCAGCAACTGATTCGTGACGGCGA
ATTTCCCCCGGGATCCTTGTTGCCGCCCGAGCGGGATCTGGCGCAGCAGCTGGGCGTCAGCCGCGCGTCGGTGCGCGAGG
CGCTGATCGCCCTGGAAGTCGTGGGCATCGTCGAGGTGCGCGTGGGACACGGGGTGCTGGTCAAGGAAGTCGACGCCATG
CCGCCGGGCTCGGTGATGCAGGCCGCGGCTCGCAAGGAGCCGTGGGCGCTCGACCCCGAGTTCGCCAGCGAGATCGAGCT
CAATCTCGACGAGGAGATACCGCCGTTTTCGCTGCTGCAGGCGCGGCGTTATCTGGAGCCGGAGAACGCGGCCCTGGCGG
CGATGAACGCCACGGACGAGGATCTCAGCGCCATCCGTGCGGCGCTGGAGCGCAACATCTACGACAACAACCATGGCGGC
GGCAACCTGGCCGGCGACCGGCTGTTGCACATCCGCATCGCCGAAGCCTCGGGTAACGCGGCCTATGCGCTGCTGATCAA
GCACCTGCTGGGTCACCAGTACGGGGTCATGTTCCGGCGCCTGCAGGAATTGTTCATGGAGACCGGCATGCCGCAGCGCT
CGCAGGAAGATCACGAGCGCCTGGTAGCGGCGATCGAGGCGCGTGACCCGGCGGCGGCGCGTCAGGCCATGGAAGTGCAC
CTCGATCATGTGCTGCGGGTGTTTTTCGCGGAGTGA

Upstream 100 bases:

>100_bases
GGCCTGACCAATGGTCGAGCCATCATCTACTGGGCTAGGTCTCGGCGGCAAGTCAATTGCCATCAACTTTAGTCGCAACG
CGGTGCGGAGAGACGACGCG

Downstream 100 bases:

>100_bases
CGGCCCGGCGGCTCGCCTCTGCGTCATCTACCAGGCGAGCACTGCGCCGTCGGCACGGGGTTCGGTGCCGCCACTGAGCA
CGCCGCTGTCGGGGTCCCGC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MPIQTIRSQRLYRQIADQLQQLIRDGEFPPGSLLPPERDLAQQLGVSRASVREALIALEVVGIVEVRVGHGVLVKEVDAM
PPGSVMQAAARKEPWALDPEFASEIELNLDEEIPPFSLLQARRYLEPENAALAAMNATDEDLSAIRAALERNIYDNNHGG
GNLAGDRLLHIRIAEASGNAAYALLIKHLLGHQYGVMFRRLQELFMETGMPQRSQEDHERLVAAIEARDPAAARQAMEVH
LDHVLRVFFAE

Sequences:

>Translated_251_residues
MPIQTIRSQRLYRQIADQLQQLIRDGEFPPGSLLPPERDLAQQLGVSRASVREALIALEVVGIVEVRVGHGVLVKEVDAM
PPGSVMQAAARKEPWALDPEFASEIELNLDEEIPPFSLLQARRYLEPENAALAAMNATDEDLSAIRAALERNIYDNNHGG
GNLAGDRLLHIRIAEASGNAAYALLIKHLLGHQYGVMFRRLQELFMETGMPQRSQEDHERLVAAIEARDPAAARQAMEVH
LDHVLRVFFAE
>Mature_250_residues
PIQTIRSQRLYRQIADQLQQLIRDGEFPPGSLLPPERDLAQQLGVSRASVREALIALEVVGIVEVRVGHGVLVKEVDAMP
PGSVMQAAARKEPWALDPEFASEIELNLDEEIPPFSLLQARRYLEPENAALAAMNATDEDLSAIRAALERNIYDNNHGGG
NLAGDRLLHIRIAEASGNAAYALLIKHLLGHQYGVMFRRLQELFMETGMPQRSQEDHERLVAAIEARDPAAARQAMEVHL
DHVLRVFFAE

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=241, Percent_Identity=33.195020746888, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082208, Length=243, Percent_Identity=32.5102880658436, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1790032, Length=241, Percent_Identity=31.5352697095436, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786303, Length=245, Percent_Identity=31.0204081632653, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1789353, Length=235, Percent_Identity=25.9574468085106, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789621, Length=246, Percent_Identity=28.0487804878049, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27932; Mature: 27801

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50949 HTH_GNTR ; PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIQTIRSQRLYRQIADQLQQLIRDGEFPPGSLLPPERDLAQQLGVSRASVREALIALEV
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
VGIVEVRVGHGVLVKEVDAMPPGSVMQAAARKEPWALDPEFASEIELNLDEEIPPFSLLQ
HHHHHHHCCCCHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCHHHHH
ARRYLEPENAALAAMNATDEDLSAIRAALERNIYDNNHGGGNLAGDRLLHIRIAEASGNA
HHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCH
AYALLIKHLLGHQYGVMFRRLQELFMETGMPQRSQEDHERLVAAIEARDPAAARQAMEVH
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
LDHVLRVFFAE
HHHHHHHHHCC
>Mature Secondary Structure 
PIQTIRSQRLYRQIADQLQQLIRDGEFPPGSLLPPERDLAQQLGVSRASVREALIALEV
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
VGIVEVRVGHGVLVKEVDAMPPGSVMQAAARKEPWALDPEFASEIELNLDEEIPPFSLLQ
HHHHHHHCCCCHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCHHHHH
ARRYLEPENAALAAMNATDEDLSAIRAALERNIYDNNHGGGNLAGDRLLHIRIAEASGNA
HHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCH
AYALLIKHLLGHQYGVMFRRLQELFMETGMPQRSQEDHERLVAAIEARDPAAARQAMEVH
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
LDHVLRVFFAE
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]