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The map label for this gene is xylR [H]

Identifier: 92113853

GI number: 92113853

Start: 1972733

End: 1973923

Strand: Direct

Name: xylR [H]

Synonym: Csal_1730

Alternate gene names: 92113853

Gene position: 1972733-1973923 (Clockwise)

Preceding gene: 92113849

Following gene: 92113862

Centisome position: 53.37

GC content: 69.1

Gene sequence:

>1191_bases
ATGGTCAGCACCTTTGCCCCTCAAGCCGCCGGTGATCTCAACTTTCTCAAGAAGCTCAACCGCAGCTCCATCCTGGCGAC
CGTACGCCGCTATCCCGGCGCCACGCGTGCCGACATCGCCTCGCGCACGCAGCTGACCAAGGCCACGGTGGGAGGCGTCG
TCCAGGCGCTGCTGGAGCGCGGCTGGCTACGCGAGGGCGAGTTGCAGCCCCGTGGCGGCGGCCGTCCCGGGCGGGCGCTG
TATCTCGACGACTCCCACCATGTCCTGCTGGGGGCGGATATCGGGGTGCGCGGCTTGCGTGTGGTGGCATGTACCCTGGG
GGGCGAGGTGCTGCTCCAGCGTTACGTCACCGAGCCGCCCACCACGCCCGAGGCCACGGCGGTGCGTCTGGCCGCCATGC
TGCGTACCCTGCGTGATGATCCGGCCATCGCCGGGCGCCATTGCCTGGGGTTGGGCGTGACGGTGCCGGGGCCGGTCTCG
CCGGTGGATCCCATCCTGCGCCTGGCGCCGAACCTGGGCTGGGTGGATGTCGCGTTTCTGGACGTGCTGCGCGAGCATCT
GACGGATCTGGACGGCATCTGGCTGCTCGACAACGAGGCCAACGCCGCGGCCTTCGGGGAGTTCTACTTCCACGACGGCA
TTCCGCCCGAGTCCATCGTCTATATCAGTGCCGCCAGCGGTATCGGCAGCGGCCTGGTCACGGGAGACAACTTCCCGCTG
GTGCCGCGTGGCGGACAGGGCCTGGTGGGCGAGATCGGTCACACCATCGTGCAGCCGGGCGGCCTGTACTGCCATTGCGG
CAACCGGGGGTGCGCCGAGACGCTGGTCAGCGGCTGGGCGATTCGTGCCGCCCTGGGCATCGCCGACGACGAGAACCTCG
AGGCGGCGATCGTGGCGCGGGGCAACGATGCCGAGGTCGATGTCACGCTGCGGCGTGCCGGCGAGGCGCTGGGGATTCTC
ATGCTCAACCTGCACCACACGCTCAATCCCGCCACGCTGGTACTCGGCGGGTCGTTGATGCGGCTCGGCGAGCGGCTGAT
CGAACCGGCACTGTCGTACTTCGAGGCGCATCAGAACGATCTGCTGCGGGGCACGCAGCGGGTGCCCGTCAAGGTCATTC
ACGACAGTACCTTCACCGCCGCGCGGGGAGCCGCCGCCCAGGTCATGGCCAAGGCGGCGTTGGAGGCGTGA

Upstream 100 bases:

>100_bases
CGCGGAACGCGCGACGAGCCGTCACGGCGCAGAGAGGCGTTGAGTAATTTGATATATTGGCCGACTCGACACGACGCACA
GCGAGGCACCCCGAATCGCC

Downstream 100 bases:

>100_bases
GGCCGGCGGTGCCGGTGTCAGGACAGGGTTAAGAGAAGCGCCGGTGTTCAGAAAATCAGGTCGGGCAGTGTCATCGACAC
GGCGGGCACGAAAGTCACCA

Product: transcriptional repressor of the xylose operon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MVSTFAPQAAGDLNFLKKLNRSSILATVRRYPGATRADIASRTQLTKATVGGVVQALLERGWLREGELQPRGGGRPGRAL
YLDDSHHVLLGADIGVRGLRVVACTLGGEVLLQRYVTEPPTTPEATAVRLAAMLRTLRDDPAIAGRHCLGLGVTVPGPVS
PVDPILRLAPNLGWVDVAFLDVLREHLTDLDGIWLLDNEANAAAFGEFYFHDGIPPESIVYISAASGIGSGLVTGDNFPL
VPRGGQGLVGEIGHTIVQPGGLYCHCGNRGCAETLVSGWAIRAALGIADDENLEAAIVARGNDAEVDVTLRRAGEALGIL
MLNLHHTLNPATLVLGGSLMRLGERLIEPALSYFEAHQNDLLRGTQRVPVKVIHDSTFTAARGAAAQVMAKAALEA

Sequences:

>Translated_396_residues
MVSTFAPQAAGDLNFLKKLNRSSILATVRRYPGATRADIASRTQLTKATVGGVVQALLERGWLREGELQPRGGGRPGRAL
YLDDSHHVLLGADIGVRGLRVVACTLGGEVLLQRYVTEPPTTPEATAVRLAAMLRTLRDDPAIAGRHCLGLGVTVPGPVS
PVDPILRLAPNLGWVDVAFLDVLREHLTDLDGIWLLDNEANAAAFGEFYFHDGIPPESIVYISAASGIGSGLVTGDNFPL
VPRGGQGLVGEIGHTIVQPGGLYCHCGNRGCAETLVSGWAIRAALGIADDENLEAAIVARGNDAEVDVTLRRAGEALGIL
MLNLHHTLNPATLVLGGSLMRLGERLIEPALSYFEAHQNDLLRGTQRVPVKVIHDSTFTAARGAAAQVMAKAALEA
>Mature_396_residues
MVSTFAPQAAGDLNFLKKLNRSSILATVRRYPGATRADIASRTQLTKATVGGVVQALLERGWLREGELQPRGGGRPGRAL
YLDDSHHVLLGADIGVRGLRVVACTLGGEVLLQRYVTEPPTTPEATAVRLAAMLRTLRDDPAIAGRHCLGLGVTVPGPVS
PVDPILRLAPNLGWVDVAFLDVLREHLTDLDGIWLLDNEANAAAFGEFYFHDGIPPESIVYISAASGIGSGLVTGDNFPL
VPRGGQGLVGEIGHTIVQPGGLYCHCGNRGCAETLVSGWAIRAALGIADDENLEAAIVARGNDAEVDVTLRRAGEALGIL
MLNLHHTLNPATLVLGGSLMRLGERLIEPALSYFEAHQNDLLRGTQRVPVKVIHDSTFTAARGAAAQVMAKAALEA

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI190014632, Length=301, Percent_Identity=28.9036544850498, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI298566325, Length=301, Percent_Identity=28.9036544850498, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI4885285, Length=301, Percent_Identity=28.9036544850498, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI298566315, Length=301, Percent_Identity=28.9036544850498, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI1786891, Length=271, Percent_Identity=25.4612546125461, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082127, Length=351, Percent_Identity=24.7863247863248, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 41884; Mature: 41884

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSTFAPQAAGDLNFLKKLNRSSILATVRRYPGATRADIASRTQLTKATVGGVVQALLER
CCCCCCCCCCCCHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GWLREGELQPRGGGRPGRALYLDDSHHVLLGADIGVRGLRVVACTLGGEVLLQRYVTEPP
CCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCEEEEEECCCHHHHHHHHHCCCC
TTPEATAVRLAAMLRTLRDDPAIAGRHCLGLGVTVPGPVSPVDPILRLAPNLGWVDVAFL
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHH
DVLREHLTDLDGIWLLDNEANAAAFGEFYFHDGIPPESIVYISAASGIGSGLVTGDNFPL
HHHHHHHCCCCCEEEEECCCCCEEEEHHHCCCCCCCCCEEEEEECCCCCCCCEECCCCCC
VPRGGQGLVGEIGHTIVQPGGLYCHCGNRGCAETLVSGWAIRAALGIADDENLEAAIVAR
CCCCCCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHCHHHHHHCCCCCCCCCCEEEEEC
GNDAEVDVTLRRAGEALGILMLNLHHTLNPATLVLGGSLMRLGERLIEPALSYFEAHQND
CCCCEEEEEHHHCCCHHEEEEEEHHCCCCCHHEECCHHHHHHHHHHHHHHHHHHHHHHHH
LLRGTQRVPVKVIHDSTFTAARGAAAQVMAKAALEA
HHCCCCCCCEEEEECCCCHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MVSTFAPQAAGDLNFLKKLNRSSILATVRRYPGATRADIASRTQLTKATVGGVVQALLER
CCCCCCCCCCCCHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GWLREGELQPRGGGRPGRALYLDDSHHVLLGADIGVRGLRVVACTLGGEVLLQRYVTEPP
CCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCEEEEEECCCHHHHHHHHHCCCC
TTPEATAVRLAAMLRTLRDDPAIAGRHCLGLGVTVPGPVSPVDPILRLAPNLGWVDVAFL
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHH
DVLREHLTDLDGIWLLDNEANAAAFGEFYFHDGIPPESIVYISAASGIGSGLVTGDNFPL
HHHHHHHCCCCCEEEEECCCCCEEEEHHHCCCCCCCCCEEEEEECCCCCCCCEECCCCCC
VPRGGQGLVGEIGHTIVQPGGLYCHCGNRGCAETLVSGWAIRAALGIADDENLEAAIVAR
CCCCCCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHCHHHHHHCCCCCCCCCCEEEEEC
GNDAEVDVTLRRAGEALGILMLNLHHTLNPATLVLGGSLMRLGERLIEPALSYFEAHQND
CCCCEEEEEHHHCCCHHEEEEEEHHCCCCCHHEECCHHHHHHHHHHHHHHHHHHHHHHHH
LLRGTQRVPVKVIHDSTFTAARGAAAQVMAKAALEA
HHCCCCCCCEEEEECCCCHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]