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The map label for this gene is yegE [H]

Identifier: 92113846

GI number: 92113846

Start: 1962132

End: 1964333

Strand: Direct

Name: yegE [H]

Synonym: Csal_1723

Alternate gene names: 92113846

Gene position: 1962132-1964333 (Clockwise)

Preceding gene: 92113845

Following gene: 92113847

Centisome position: 53.08

GC content: 65.58

Gene sequence:

>2202_bases
ATGCCCTCGCGTCGGCGCGGTGCGAGTGACTGCCAGTACGACGCCTGTGCAACGAGACGAATCGGGGCACGGGGTTTGCT
CGCGACAGCCGCTGGGATAGGCTTGTCACTCGTTTACATTCCTGACCGACCCCGGCGCCGCACAATGCGAAGATGGCCCT
ATCGTGCAAGACGGTTTTCCACGCTACTGCCCAGGATATTGCCCAGAACGCTGCTTCCGGGCACGCTATTCGGTCGTCTT
GTCATGGGCATCGGTCTGGGCTGGTTGGTGCTGGTGGCTGCCATTCTCTGGGTATCGCTGCGTGGCGGCAGCGATCTGGC
GGACGAGATCAACCGTTCGCACCTGGATTATGAAGCCTCGCTGATCGCGCGCGACATTCAGCAGGCGATCACGTTGCGGC
TCGATACGCTGGAAACCCTTGCGACCGCCCAGGCCGGGCAATTGCGGGGACGCGGTGAATCCCTCGACGAGGCGAGTGTC
GAGGATGTGCAACGGCGTCTGAGCCGTCACTCGGCCTTGCTCGAGCTGTTCGATTCCGCCTTCGTGACCGACGCGCAAGG
CGAGGTCAAGGCTTTCATGCCGTCGTTGTCGGGCGCCGTGGGCCTGAATGTCGCCGAGCGTGAGTACTTTCGCTTCCTCC
AAGAGGTCGGGCGCCCCTTCGTGGGGCGTCCGATCATCAGCAAGCTGCACGATCGACGTCCCCTGGTGGTGATGGGCGTG
CCCCTGCGCGACGACGAAGGCGACTTCGCCGGCATGCTGGGGGGCGTGGTCAACCTGCGCGATGGCCGCTTCTTTCTCGA
TCTGCGCAGCCTGCGTATCGGCGAGCGGGGCTATGCGGTGTTGATGACCAGCGATGGAACGGTACTCAGTCATCCCGATC
AGAACCGGATCATGCAGCAAACGCCGGCGGCATGGGAGGGGCCGTTGCTCGAGAAGGCGCTGGACGGCTGGCAGGGCACG
GGTATCGGGCGACTGGTCAATGGCGAGTCGGCGTTGATGAGCTTCCATCAGGTCTGGCAGCCGGGCTGGGTCGTTGGCGT
CTTCCTGCCGGAAAGCCAAGTGCGGCAGCCGATCCTGGATTACGTGCGTCGCCAGGGGTGGGTGGCCGCGGTGGTGGTAC
TGTCGATGCTGCCGCTGTTGTGGTGGCTACTGCGCCTGGGATTGTCGCCCTTGCGGCGCCTGGCCCGGCAGATCGCGCTG
GTGGGGCAGGGCGAGATTTCGCGCATCACCCTGGATACGTCGCTGGATGAGTTGCGCCGTATCGCCCGGACGTTCAACGA
TGTCGAGCATGAGCGCGGCCTCGAGCGCGCCGAGCGCCATCGTCGGCAGGCGTATCTCGACGCGGTGCTGCGTTCCTCGC
CGTTGCCGATGTTCCTGGCGAGCCTCGAGGGCCGCATCACCTATGTCAATCCGGCCCTGGAGAGTCTGACGGGGCTGTCG
ACGCCGGCCTTCCAGCGCCGCGAATGGCTGCGCCGCCTGCACCCCGAGGACCGTCCGGTGCTGTTCGCGCTGTGGCGTCA
TGCGGTGAACGGCGGTCACGAGCTGCACCGACAGCTGCGCTTCGCCTGCGGCGAACGCGGCATGATGTGGCTGGAGCTCT
ACACCAGCCAGGTCATGAACGATGGCCGGCCCCAGGGTGTGGTGGGCTTCGTCAAGGACATCACTCACCTGCGTGAACAG
CAGAAACGCCAGCTCTGGGAGGCCGAGCACGATCCGCTGACGGGGCTGCTCAACCGGCGTGGCTTCGACCGACGCCTGAA
CGATACCTTCATGGCCTTCAAGGAGCGCGGCGATGTGGCAGCGCTGATCCTGTTCGACCTGGACAGCTTCAAGCCCATCA
ACGACGACGGCGGTCATGCCCTGGGCGACGAGATGCTCGATGCCATCGCCCGTTGCCTGGAAGGCTGCGTGCGTCGCGAC
GACCATCTGGCCCGGCTCGGCGGCGACGAGTTCGCGATTCTGCTCCCCGGCTGCGGCCACCAGCAGGCCGTGCGTATCGC
CGACAAGGTACGCCATGCGGTGAGCGAGCTTTCCGTGGTGCAAGATGGCAAGCGTTACCGCGTCACGGCGAGCCTGGGTG
TCTCGTGTCTGGGGAGCGACGATGACGAGGCCCAGGCCGTGGTCAAGCGCGCCGACGCGGCGAGCTACGAGGCCAAGGCG
CAGGGCAAGAATCGGATGGTGGCCGATGCGCGCTGCGGATGA

Upstream 100 bases:

>100_bases
CGCGCGGGCCAACTCCGTGGCGTCGTAGCACTTTCTCTGTCGTCTTTTTTTCTACCGTGTTTGGCCTTGACGCCGGTGCT
TCGTGCACCGGCGTTTTTTT

Downstream 100 bases:

>100_bases
TGCCACCGGCCGTCGAGGCGACAGCGCCCGACGACATCATGGGGACGCACGATGACACACGATACCCTGGTACTCGGGGC
CGGCATGGTCGGCGTGGGCG

Product: PAS/PAC sensor-containing diguanylate cyclase

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 733; Mature: 732

Protein sequence:

>733_residues
MPSRRRGASDCQYDACATRRIGARGLLATAAGIGLSLVYIPDRPRRRTMRRWPYRARRFSTLLPRILPRTLLPGTLFGRL
VMGIGLGWLVLVAAILWVSLRGGSDLADEINRSHLDYEASLIARDIQQAITLRLDTLETLATAQAGQLRGRGESLDEASV
EDVQRRLSRHSALLELFDSAFVTDAQGEVKAFMPSLSGAVGLNVAEREYFRFLQEVGRPFVGRPIISKLHDRRPLVVMGV
PLRDDEGDFAGMLGGVVNLRDGRFFLDLRSLRIGERGYAVLMTSDGTVLSHPDQNRIMQQTPAAWEGPLLEKALDGWQGT
GIGRLVNGESALMSFHQVWQPGWVVGVFLPESQVRQPILDYVRRQGWVAAVVVLSMLPLLWWLLRLGLSPLRRLARQIAL
VGQGEISRITLDTSLDELRRIARTFNDVEHERGLERAERHRRQAYLDAVLRSSPLPMFLASLEGRITYVNPALESLTGLS
TPAFQRREWLRRLHPEDRPVLFALWRHAVNGGHELHRQLRFACGERGMMWLELYTSQVMNDGRPQGVVGFVKDITHLREQ
QKRQLWEAEHDPLTGLLNRRGFDRRLNDTFMAFKERGDVAALILFDLDSFKPINDDGGHALGDEMLDAIARCLEGCVRRD
DHLARLGGDEFAILLPGCGHQQAVRIADKVRHAVSELSVVQDGKRYRVTASLGVSCLGSDDDEAQAVVKRADAASYEAKA
QGKNRMVADARCG

Sequences:

>Translated_733_residues
MPSRRRGASDCQYDACATRRIGARGLLATAAGIGLSLVYIPDRPRRRTMRRWPYRARRFSTLLPRILPRTLLPGTLFGRL
VMGIGLGWLVLVAAILWVSLRGGSDLADEINRSHLDYEASLIARDIQQAITLRLDTLETLATAQAGQLRGRGESLDEASV
EDVQRRLSRHSALLELFDSAFVTDAQGEVKAFMPSLSGAVGLNVAEREYFRFLQEVGRPFVGRPIISKLHDRRPLVVMGV
PLRDDEGDFAGMLGGVVNLRDGRFFLDLRSLRIGERGYAVLMTSDGTVLSHPDQNRIMQQTPAAWEGPLLEKALDGWQGT
GIGRLVNGESALMSFHQVWQPGWVVGVFLPESQVRQPILDYVRRQGWVAAVVVLSMLPLLWWLLRLGLSPLRRLARQIAL
VGQGEISRITLDTSLDELRRIARTFNDVEHERGLERAERHRRQAYLDAVLRSSPLPMFLASLEGRITYVNPALESLTGLS
TPAFQRREWLRRLHPEDRPVLFALWRHAVNGGHELHRQLRFACGERGMMWLELYTSQVMNDGRPQGVVGFVKDITHLREQ
QKRQLWEAEHDPLTGLLNRRGFDRRLNDTFMAFKERGDVAALILFDLDSFKPINDDGGHALGDEMLDAIARCLEGCVRRD
DHLARLGGDEFAILLPGCGHQQAVRIADKVRHAVSELSVVQDGKRYRVTASLGVSCLGSDDDEAQAVVKRADAASYEAKA
QGKNRMVADARCG
>Mature_732_residues
PSRRRGASDCQYDACATRRIGARGLLATAAGIGLSLVYIPDRPRRRTMRRWPYRARRFSTLLPRILPRTLLPGTLFGRLV
MGIGLGWLVLVAAILWVSLRGGSDLADEINRSHLDYEASLIARDIQQAITLRLDTLETLATAQAGQLRGRGESLDEASVE
DVQRRLSRHSALLELFDSAFVTDAQGEVKAFMPSLSGAVGLNVAEREYFRFLQEVGRPFVGRPIISKLHDRRPLVVMGVP
LRDDEGDFAGMLGGVVNLRDGRFFLDLRSLRIGERGYAVLMTSDGTVLSHPDQNRIMQQTPAAWEGPLLEKALDGWQGTG
IGRLVNGESALMSFHQVWQPGWVVGVFLPESQVRQPILDYVRRQGWVAAVVVLSMLPLLWWLLRLGLSPLRRLARQIALV
GQGEISRITLDTSLDELRRIARTFNDVEHERGLERAERHRRQAYLDAVLRSSPLPMFLASLEGRITYVNPALESLTGLST
PAFQRREWLRRLHPEDRPVLFALWRHAVNGGHELHRQLRFACGERGMMWLELYTSQVMNDGRPQGVVGFVKDITHLREQQ
KRQLWEAEHDPLTGLLNRRGFDRRLNDTFMAFKERGDVAALILFDLDSFKPINDDGGHALGDEMLDAIARCLEGCVRRDD
HLARLGGDEFAILLPGCGHQQAVRIADKVRHAVSELSVVQDGKRYRVTASLGVSCLGSDDDEAQAVVKRADAASYEAKAQ
GKNRMVADARCG

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=347, Percent_Identity=27.0893371757925, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI87081881, Length=298, Percent_Identity=30.5369127516779, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1786584, Length=171, Percent_Identity=32.7485380116959, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=32.1212121212121, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI87082007, Length=177, Percent_Identity=31.638418079096, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI145693134, Length=157, Percent_Identity=31.8471337579618, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1787802, Length=178, Percent_Identity=30.3370786516854, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1788085, Length=164, Percent_Identity=33.5365853658537, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1788956, Length=174, Percent_Identity=33.9080459770115, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787541, Length=203, Percent_Identity=28.0788177339901, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1787816, Length=155, Percent_Identity=30.9677419354839, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787056, Length=215, Percent_Identity=27.906976744186, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081974, Length=106, Percent_Identity=33.9622641509434, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081977, Length=176, Percent_Identity=28.4090909090909, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 82129; Mature: 81997

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSRRRGASDCQYDACATRRIGARGLLATAAGIGLSLVYIPDRPRRRTMRRWPYRARRFS
CCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHCCHHHHHHH
TLLPRILPRTLLPGTLFGRLVMGIGLGWLVLVAAILWVSLRGGSDLADEINRSHLDYEAS
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHH
LIARDIQQAITLRLDTLETLATAQAGQLRGRGESLDEASVEDVQRRLSRHSALLELFDSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FVTDAQGEVKAFMPSLSGAVGLNVAEREYFRFLQEVGRPFVGRPIISKLHDRRPLVVMGV
HCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEEC
PLRDDEGDFAGMLGGVVNLRDGRFFLDLRSLRIGERGYAVLMTSDGTVLSHPDQNRIMQQ
CCCCCCCCHHHHHHCCEEECCCEEEEEHHHHEECCCCCEEEEECCCCEECCCCHHHHHHH
TPAAWEGPLLEKALDGWQGTGIGRLVNGESALMSFHQVWQPGWVVGVFLPESQVRQPILD
CCCCCCCHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHH
YVRRQGWVAAVVVLSMLPLLWWLLRLGLSPLRRLARQIALVGQGEISRITLDTSLDELRR
HHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHH
IARTFNDVEHERGLERAERHRRQAYLDAVLRSSPLPMFLASLEGRITYVNPALESLTGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEECHHHHHHHCCC
TPAFQRREWLRRLHPEDRPVLFALWRHAVNGGHELHRQLRFACGERGMMWLELYTSQVMN
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
DGRPQGVVGFVKDITHLREQQKRQLWEAEHDPLTGLLNRRGFDRRLNDTFMAFKERGDVA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCEE
ALILFDLDSFKPINDDGGHALGDEMLDAIARCLEGCVRRDDHLARLGGDEFAILLPGCGH
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEECCCCC
QQAVRIADKVRHAVSELSVVQDGKRYRVTASLGVSCLGSDDDEAQAVVKRADAASYEAKA
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEECCCCCHHHHHHHHHHHHHCCHHHH
QGKNRMVADARCG
CCCCCCCCCCCCC
>Mature Secondary Structure 
PSRRRGASDCQYDACATRRIGARGLLATAAGIGLSLVYIPDRPRRRTMRRWPYRARRFS
CCCCCCCCCCCHHHHHHHHCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHCCHHHHHHH
TLLPRILPRTLLPGTLFGRLVMGIGLGWLVLVAAILWVSLRGGSDLADEINRSHLDYEAS
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHH
LIARDIQQAITLRLDTLETLATAQAGQLRGRGESLDEASVEDVQRRLSRHSALLELFDSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FVTDAQGEVKAFMPSLSGAVGLNVAEREYFRFLQEVGRPFVGRPIISKLHDRRPLVVMGV
HCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEEC
PLRDDEGDFAGMLGGVVNLRDGRFFLDLRSLRIGERGYAVLMTSDGTVLSHPDQNRIMQQ
CCCCCCCCHHHHHHCCEEECCCEEEEEHHHHEECCCCCEEEEECCCCEECCCCHHHHHHH
TPAAWEGPLLEKALDGWQGTGIGRLVNGESALMSFHQVWQPGWVVGVFLPESQVRQPILD
CCCCCCCHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHH
YVRRQGWVAAVVVLSMLPLLWWLLRLGLSPLRRLARQIALVGQGEISRITLDTSLDELRR
HHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHH
IARTFNDVEHERGLERAERHRRQAYLDAVLRSSPLPMFLASLEGRITYVNPALESLTGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEECHHHHHHHCCC
TPAFQRREWLRRLHPEDRPVLFALWRHAVNGGHELHRQLRFACGERGMMWLELYTSQVMN
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
DGRPQGVVGFVKDITHLREQQKRQLWEAEHDPLTGLLNRRGFDRRLNDTFMAFKERGDVA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCEE
ALILFDLDSFKPINDDGGHALGDEMLDAIARCLEGCVRRDDHLARLGGDEFAILLPGCGH
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEECCCCC
QQAVRIADKVRHAVSELSVVQDGKRYRVTASLGVSCLGSDDDEAQAVVKRADAASYEAKA
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEECCCCCHHHHHHHHHHHHHCCHHHH
QGKNRMVADARCG
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]