Click here to switch to the map view.

The map label for this gene is wzc [C]

Identifier: 92113836

GI number: 92113836

Start: 1949292

End: 1951487

Strand: Direct

Name: wzc [C]

Synonym: Csal_1713

Alternate gene names: 92113836

Gene position: 1949292-1951487 (Clockwise)

Preceding gene: 92113835

Following gene: 92113837

Centisome position: 52.73

GC content: 64.25

Gene sequence:

>2196_bases
ATGAATCTCAATGTACCTGCCCCACAAACCAGCAAGACCGACAACGACATGGAGCTGGGACGCATCCTGGGCCTGTTGTT
CGACGCCAAGGGACTGGTAATCAGTCTGATCGTGCTGTTCGCACTCGTGGGGGCGGCGTATGCCTTCTTCGCGACGCCTA
TCTTTCGGGCCGACTCACTGGTCCAGGTGGAAACCAAGACCCCCAAGAATCCACTCGCGGATGCCACGGCGTCCGCCATG
ATGCCGCAGTTGCCGCCCTCGCGCGCGGAAATGGAAATCATGAAATCGCGCATGGTGCTGGGCCGCGCGGTGGATCTGCT
CAACCTCGACATCCGCGTCGAGCCGGTGCGCGTGCCGGTCATCGGCGGGTTCCTGCAGCGCCACCAGATCGCCGCACCCG
CGTTCGCCCAGGACTGGGGCTACGCCTGGGGCGACGACCATATCGAACTCGCCGGCATGCCGGTGGCCGGTGAGTATCTG
GGCAAGACCTTCACTCTCGAAGTGCTCGACGAGACCCGCTATGCCTTGCATTACCGGGGCGAACGCCTGGGCGAGGGCAG
CGTCGGCGAGGAAGCGAGTTTCCTCGGTGGTGCGGTAGGCGTTGAAGTCGAGTCGATCGCGGCGGCACCGGGTGCGACCT
TCAAGTTGACCCACGCCCAGCGCGTGGTGGCTGTCGACCAATTGCGCGACAACTTCGGCGTCGCCGAGCAAGGCAATGGC
ACGGGCATCATCTCCTGGAGCCTGACCGATCCATCGCCGGCTCTGGCCGAGCGGGTGCTGGCCACCATCGGCGATATCTA
CGTCACCCAGAACATTCAGCGTCAGTCCGAGGAGGCGCGCAAGAGCCTGGAATTCTTGAGCAAGCAGGTGCCGGAGGTGC
GTGGCGAACTCGCCGGGGCCGAGCAGCAGCTCAATGCCTACCGCTCCGAGCACGACAGCGTGGATATTTCCATGGAGACC
AAGTCGGTGCTCGACCGCGTGGTCAACCTGGAAAGCCAGCTCAACGAGCTCGAATTCTCCGAGGCCGAGATCTCGCGGCG
CTTCACGCCCAGCCACCCGACCTACGCGGCCCTGCTGGAGAAGAAGGCACAGCTCAAGAGGGAGCTCAACACGTTGGAAG
AGCGCATCAACGGCATGCCGGAAACCCAGCAGGAAGTGCTGCGCATGCAGCGCGATGTTTCGGTCAATCAGGCGATCTAC
GTGCAGCTGCGCAACAAGGTGCAGGAAATGCAGATCGCCGAGGCCAGCACGGTGGGCAACGTTCGGGTGCTGGACGACTC
CGAGTCGTTCCCGCGTCCGGTCTCGCCCAACAAGATCATGATCATCGCCCTGGCGACCATACTGGGCGCGGCCTTCGCAG
TGGCAGTGGTGATGCTGCGCGCGATGTTCAACCGCGGTCTGGAAAGCCCCGACCAGCTCGAACAACTGGGCTTGCCGGTC
TACGCCATCGTGCCCAAGTCCGACGATCAGAACCGGCTCAGCCGCCGCATTCGTCGCGGCGGGCGCTCGCAGAGCGTGCC
GGCGGGGCTTTTGGCCTGGCATCGTCCGCTGGATGTCTCCATCGAGGCGCTGCGCAGCCTGCGTACCAGCCTGCACTTCG
CGATGCTGGACAGCACGGACAACCGCTTGATGATCACCGGCCCCAGTCCGGCGGTGGGCAAGAGCTTCATCACCGCCAAC
CTGGCGGCGGTATGCGCCCAGAACGGCCAGCGCGTGCTGGTGATCGACGGCGACATGCGCAAGGGCCAGATGCACAAGAT
CTTCAAGGGCCCCTCCGAGGATGGCCTGAGCGAGATTCTCGCCGGCCGCCATACGCTGGAAGAAATGGTGCGCCCGGTGG
AAAGCATCGAGGGACTCGAGTACCTGGCGCGCGGGGTGGTACCGCCGAATGCCTCGGAACTGCTGGCCTCAGAGCGCTTC
ACCGAGCTCCTGGCCAAGGCCAGCGAGCGCTATGACCTGGTGATCGTCGATTCGCCGCCGGTGCTGGCGGTGACGGATGC
CACGGTCATCGGCAAGCGCGTGGGCACGACGCTGATGGTGGCACGCTTCCAGCTCAATCCGCCCAAGGAAATCGAGCTGG
CGATGCGGCGGCTGGATACCGGCGGGGTACGCGTCAAGGGCGCGATCCTCAACGGCCTGGAGCGCAAGGCGGCCACGGCG
TACACCTATGGTTACTACAACTATTCCTACCGCTAA

Upstream 100 bases:

>100_bases
CGATAACTAGTAAGCCGTCATTGTCTCGAGGCCGCCGCCGTCCGCCGCCAGGCGCCGGGGGCGGCCCTCGATACCCACAT
TCTCATGGAGTGGGAATTCT

Downstream 100 bases:

>100_bases
TCCTTTCCTGATGCTGACCTTGCGTTCCGCCGAGCGGCCCTTGGGGGCCGTGAGGCATGCGAGACGCGTTCGAGGAGTCA
ACCTTGCTGATTCGCTATAC

Product: protein-tyrosine kinase

Products: ADP; protein tyrosine phosphate [C]

Alternate protein names: ORF6 [H]

Number of amino acids: Translated: 731; Mature: 731

Protein sequence:

>731_residues
MNLNVPAPQTSKTDNDMELGRILGLLFDAKGLVISLIVLFALVGAAYAFFATPIFRADSLVQVETKTPKNPLADATASAM
MPQLPPSRAEMEIMKSRMVLGRAVDLLNLDIRVEPVRVPVIGGFLQRHQIAAPAFAQDWGYAWGDDHIELAGMPVAGEYL
GKTFTLEVLDETRYALHYRGERLGEGSVGEEASFLGGAVGVEVESIAAAPGATFKLTHAQRVVAVDQLRDNFGVAEQGNG
TGIISWSLTDPSPALAERVLATIGDIYVTQNIQRQSEEARKSLEFLSKQVPEVRGELAGAEQQLNAYRSEHDSVDISMET
KSVLDRVVNLESQLNELEFSEAEISRRFTPSHPTYAALLEKKAQLKRELNTLEERINGMPETQQEVLRMQRDVSVNQAIY
VQLRNKVQEMQIAEASTVGNVRVLDDSESFPRPVSPNKIMIIALATILGAAFAVAVVMLRAMFNRGLESPDQLEQLGLPV
YAIVPKSDDQNRLSRRIRRGGRSQSVPAGLLAWHRPLDVSIEALRSLRTSLHFAMLDSTDNRLMITGPSPAVGKSFITAN
LAAVCAQNGQRVLVIDGDMRKGQMHKIFKGPSEDGLSEILAGRHTLEEMVRPVESIEGLEYLARGVVPPNASELLASERF
TELLAKASERYDLVIVDSPPVLAVTDATVIGKRVGTTLMVARFQLNPPKEIELAMRRLDTGGVRVKGAILNGLERKAATA
YTYGYYNYSYR

Sequences:

>Translated_731_residues
MNLNVPAPQTSKTDNDMELGRILGLLFDAKGLVISLIVLFALVGAAYAFFATPIFRADSLVQVETKTPKNPLADATASAM
MPQLPPSRAEMEIMKSRMVLGRAVDLLNLDIRVEPVRVPVIGGFLQRHQIAAPAFAQDWGYAWGDDHIELAGMPVAGEYL
GKTFTLEVLDETRYALHYRGERLGEGSVGEEASFLGGAVGVEVESIAAAPGATFKLTHAQRVVAVDQLRDNFGVAEQGNG
TGIISWSLTDPSPALAERVLATIGDIYVTQNIQRQSEEARKSLEFLSKQVPEVRGELAGAEQQLNAYRSEHDSVDISMET
KSVLDRVVNLESQLNELEFSEAEISRRFTPSHPTYAALLEKKAQLKRELNTLEERINGMPETQQEVLRMQRDVSVNQAIY
VQLRNKVQEMQIAEASTVGNVRVLDDSESFPRPVSPNKIMIIALATILGAAFAVAVVMLRAMFNRGLESPDQLEQLGLPV
YAIVPKSDDQNRLSRRIRRGGRSQSVPAGLLAWHRPLDVSIEALRSLRTSLHFAMLDSTDNRLMITGPSPAVGKSFITAN
LAAVCAQNGQRVLVIDGDMRKGQMHKIFKGPSEDGLSEILAGRHTLEEMVRPVESIEGLEYLARGVVPPNASELLASERF
TELLAKASERYDLVIVDSPPVLAVTDATVIGKRVGTTLMVARFQLNPPKEIELAMRRLDTGGVRVKGAILNGLERKAATA
YTYGYYNYSYR
>Mature_731_residues
MNLNVPAPQTSKTDNDMELGRILGLLFDAKGLVISLIVLFALVGAAYAFFATPIFRADSLVQVETKTPKNPLADATASAM
MPQLPPSRAEMEIMKSRMVLGRAVDLLNLDIRVEPVRVPVIGGFLQRHQIAAPAFAQDWGYAWGDDHIELAGMPVAGEYL
GKTFTLEVLDETRYALHYRGERLGEGSVGEEASFLGGAVGVEVESIAAAPGATFKLTHAQRVVAVDQLRDNFGVAEQGNG
TGIISWSLTDPSPALAERVLATIGDIYVTQNIQRQSEEARKSLEFLSKQVPEVRGELAGAEQQLNAYRSEHDSVDISMET
KSVLDRVVNLESQLNELEFSEAEISRRFTPSHPTYAALLEKKAQLKRELNTLEERINGMPETQQEVLRMQRDVSVNQAIY
VQLRNKVQEMQIAEASTVGNVRVLDDSESFPRPVSPNKIMIIALATILGAAFAVAVVMLRAMFNRGLESPDQLEQLGLPV
YAIVPKSDDQNRLSRRIRRGGRSQSVPAGLLAWHRPLDVSIEALRSLRTSLHFAMLDSTDNRLMITGPSPAVGKSFITAN
LAAVCAQNGQRVLVIDGDMRKGQMHKIFKGPSEDGLSEILAGRHTLEEMVRPVESIEGLEYLARGVVPPNASELLASERF
TELLAKASERYDLVIVDSPPVLAVTDATVIGKRVGTTLMVARFQLNPPKEIELAMRRLDTGGVRVKGAILNGLERKAATA
YTYGYYNYSYR

Specific function: Required For The Extracellular Polysaccharide Colanic Acid Synthesis. The Autophosphorylated Form Is Inactive. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG3206

COG function: function code M; Uncharacterized protein involved in exopolysaccharide biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the etk/wzc family [H]

Homologues:

Organism=Escherichia coli, GI87082032, Length=724, Percent_Identity=43.5082872928177, Blast_Score=587, Evalue=1e-168,
Organism=Escherichia coli, GI1787216, Length=727, Percent_Identity=42.5034387895461, Blast_Score=565, Evalue=1e-162,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR005702
- InterPro:   IPR003856 [H]

Pfam domain/function: PF01656 CbiA; PF02706 Wzz [H]

EC number: 2.7.1.112 [C]

Molecular weight: Translated: 80227; Mature: 80227

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLNVPAPQTSKTDNDMELGRILGLLFDAKGLVISLIVLFALVGAAYAFFATPIFRADSL
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VQVETKTPKNPLADATASAMMPQLPPSRAEMEIMKSRMVLGRAVDLLNLDIRVEPVRVPV
EEEECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEECH
IGGFLQRHQIAAPAFAQDWGYAWGDDHIELAGMPVAGEYLGKTFTLEVLDETRYALHYRG
HHHHHHHHHHCCCCHHHHCCCCCCCCCEEEECCCCCHHHHCCEEEEEEHHCHHHHHHCCC
ERLGEGSVGEEASFLGGAVGVEVESIAAAPGATFKLTHAQRVVAVDQLRDNFGVAEQGNG
CCCCCCCCCCCHHHHCCHHCCCHHHHHCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCC
TGIISWSLTDPSPALAERVLATIGDIYVTQNIQRQSEEARKSLEFLSKQVPEVRGELAGA
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EQQLNAYRSEHDSVDISMETKSVLDRVVNLESQLNELEFSEAEISRRFTPSHPTYAALLE
HHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHH
KKAQLKRELNTLEERINGMPETQQEVLRMQRDVSVNQAIYVQLRNKVQEMQIAEASTVGN
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
VRVLDDSESFPRPVSPNKIMIIALATILGAAFAVAVVMLRAMFNRGLESPDQLEQLGLPV
EEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCE
YAIVPKSDDQNRLSRRIRRGGRSQSVPAGLLAWHRPLDVSIEALRSLRTSLHFAMLDSTD
EEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHEEEEECCC
NRLMITGPSPAVGKSFITANLAAVCAQNGQRVLVIDGDMRKGQMHKIFKGPSEDGLSEIL
CEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHCCCCCCCHHHHH
AGRHTLEEMVRPVESIEGLEYLARGVVPPNASELLASERFTELLAKASERYDLVIVDSPP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
VLAVTDATVIGKRVGTTLMVARFQLNPPKEIELAMRRLDTGGVRVKGAILNGLERKAATA
EEEEECHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHE
YTYGYYNYSYR
EEEEEEEECCC
>Mature Secondary Structure
MNLNVPAPQTSKTDNDMELGRILGLLFDAKGLVISLIVLFALVGAAYAFFATPIFRADSL
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VQVETKTPKNPLADATASAMMPQLPPSRAEMEIMKSRMVLGRAVDLLNLDIRVEPVRVPV
EEEECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEECH
IGGFLQRHQIAAPAFAQDWGYAWGDDHIELAGMPVAGEYLGKTFTLEVLDETRYALHYRG
HHHHHHHHHHCCCCHHHHCCCCCCCCCEEEECCCCCHHHHCCEEEEEEHHCHHHHHHCCC
ERLGEGSVGEEASFLGGAVGVEVESIAAAPGATFKLTHAQRVVAVDQLRDNFGVAEQGNG
CCCCCCCCCCCHHHHCCHHCCCHHHHHCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCC
TGIISWSLTDPSPALAERVLATIGDIYVTQNIQRQSEEARKSLEFLSKQVPEVRGELAGA
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EQQLNAYRSEHDSVDISMETKSVLDRVVNLESQLNELEFSEAEISRRFTPSHPTYAALLE
HHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHH
KKAQLKRELNTLEERINGMPETQQEVLRMQRDVSVNQAIYVQLRNKVQEMQIAEASTVGN
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
VRVLDDSESFPRPVSPNKIMIIALATILGAAFAVAVVMLRAMFNRGLESPDQLEQLGLPV
EEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCE
YAIVPKSDDQNRLSRRIRRGGRSQSVPAGLLAWHRPLDVSIEALRSLRTSLHFAMLDSTD
EEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHEEEEECCC
NRLMITGPSPAVGKSFITANLAAVCAQNGQRVLVIDGDMRKGQMHKIFKGPSEDGLSEIL
CEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHCCCCCCCHHHHH
AGRHTLEEMVRPVESIEGLEYLARGVVPPNASELLASERFTELLAKASERYDLVIVDSPP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
VLAVTDATVIGKRVGTTLMVARFQLNPPKEIELAMRRLDTGGVRVKGAILNGLERKAATA
EEEEECHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHE
YTYGYYNYSYR
EEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; a protein tyrosine [C]

Specific reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7896702 [H]