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The map label for this gene is fabF [H]

Identifier: 92113727

GI number: 92113727

Start: 1823473

End: 1824705

Strand: Direct

Name: fabF [H]

Synonym: Csal_1603

Alternate gene names: 92113727

Gene position: 1823473-1824705 (Clockwise)

Preceding gene: 92113726

Following gene: 92113728

Centisome position: 49.33

GC content: 65.21

Gene sequence:

>1233_bases
ATGCCTCGTAAAAGGGTCGTGGTGACCGGATTGGGCCTAGTGACCCCTGTCGGTAACACTGTCAAGGAAAGCTGGGACAA
CATCCTGGCAGGCAAGAGCGGCATCTCGCTGATCGACCAGTTCGATACGTCGGGATTCAACACGCGCTTCGGCGGTTCGG
TGAAGGACTTCGATATCAGCCCGTACCTGAACCCCAAGGATGCGCGCAAGATGGATCTGTTCATCCAGTACGGAATCGCG
GCGGCCGGGCAGGCCATCGCCGACGCCGGGCTGGAAAGCAACGACGACAACGCGGACCGCATCGGTGTGGCGATCGGCTC
GGGCATCGGCGGTCTGCCGATGATCGAGCACAACCACAACGCACTGAACCGTGGCGGGCCGCGCAAGATTTCCCCCTTCT
TCGTGCCGGGGTCGATCATCAACATGATCTCCGGCAATCTGGCGATCCAGCATGGCTTTCGCGGTCCCAACATCGCCATT
ACCACGGCGTGCACCACCGGGACGCACAACATCGGCTACGCGGCTCGCACCATCGCGTACGGCGATGCGGATGCCATGGT
CTGCGGCGGGGCCGAAATGGCCACCACGCCGCTGGGCCTGGGCGGGTTCTCGGCGGCCCGGGCACTGTCCACGCGCAATG
ACGATCCCGCCGCGGCGAGCCGCCCCTGGGATCGCGAGCGCGACGGTTTCGTGCTCTCCGACGGGGCCGGGGTGCTGGTG
CTGGAAGAGTACGAGCATGCCAAGCGTCGAGGCGCGCCCATCTATGCCGAGCTGCTGGGCTTCGGCATGAGCGACGACGC
CTATCACATGACCGCGCCCAATGGCAGCGGCGCCGAGATGGCGATGCGCAACGCGGTCAAGGATGCGGGCATCGAGGCCG
GCCAGCTGGGCTACATCAACGCGCACGGTACCTCCACCCAGGCGGGCGACGTCGCCGAGAGCCAGGCGGTGGAGCGCGTC
ATGGGCGAGGCGGCCAAGTCCGTGGCGGTGAGTTCCACGAAGTCGATGATCGGCCACTTGCTGGGTGCCGCCGGCGCGGT
CGAGGCGATCTTCAGCATCCTCGCCATTCGCGATCAGGTCGCGCCGCCGACCATCAATCTCGACGATCCCGATGAAGGCT
GCGTGCTCGACTACGTGCCCAACACGGCGCGCGAGATGGCCATCGACTACACCCTGTCGAACTCCTTCGGCTTCGGTGGT
ACCAACGGGTCACTGATCTTCGGTCGTACCTGA

Upstream 100 bases:

>100_bases
GTTTGTGCATGCTTGCCGTCTCCATCCCGGCGGCGAATCGGGTATAATGCGCGCCAAACACGGCCATGCCGTGCCAACTC
GCAAGTCTGGAGGAGAGCTG

Downstream 100 bases:

>100_bases
TCGCCATGGGTGACGAGGCGGTACCGTTCGATGATCGGGGCCTCGCTTACGGGGACGGTCTCTTCGAGACCGTCCTCGTG
CGTGACGGGCAGCCTGTCCT

Product: 3-oxoacyl-[acyl-carrier-protein] synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MPRKRVVVTGLGLVTPVGNTVKESWDNILAGKSGISLIDQFDTSGFNTRFGGSVKDFDISPYLNPKDARKMDLFIQYGIA
AAGQAIADAGLESNDDNADRIGVAIGSGIGGLPMIEHNHNALNRGGPRKISPFFVPGSIINMISGNLAIQHGFRGPNIAI
TTACTTGTHNIGYAARTIAYGDADAMVCGGAEMATTPLGLGGFSAARALSTRNDDPAAASRPWDRERDGFVLSDGAGVLV
LEEYEHAKRRGAPIYAELLGFGMSDDAYHMTAPNGSGAEMAMRNAVKDAGIEAGQLGYINAHGTSTQAGDVAESQAVERV
MGEAAKSVAVSSTKSMIGHLLGAAGAVEAIFSILAIRDQVAPPTINLDDPDEGCVLDYVPNTAREMAIDYTLSNSFGFGG
TNGSLIFGRT

Sequences:

>Translated_410_residues
MPRKRVVVTGLGLVTPVGNTVKESWDNILAGKSGISLIDQFDTSGFNTRFGGSVKDFDISPYLNPKDARKMDLFIQYGIA
AAGQAIADAGLESNDDNADRIGVAIGSGIGGLPMIEHNHNALNRGGPRKISPFFVPGSIINMISGNLAIQHGFRGPNIAI
TTACTTGTHNIGYAARTIAYGDADAMVCGGAEMATTPLGLGGFSAARALSTRNDDPAAASRPWDRERDGFVLSDGAGVLV
LEEYEHAKRRGAPIYAELLGFGMSDDAYHMTAPNGSGAEMAMRNAVKDAGIEAGQLGYINAHGTSTQAGDVAESQAVERV
MGEAAKSVAVSSTKSMIGHLLGAAGAVEAIFSILAIRDQVAPPTINLDDPDEGCVLDYVPNTAREMAIDYTLSNSFGFGG
TNGSLIFGRT
>Mature_409_residues
PRKRVVVTGLGLVTPVGNTVKESWDNILAGKSGISLIDQFDTSGFNTRFGGSVKDFDISPYLNPKDARKMDLFIQYGIAA
AGQAIADAGLESNDDNADRIGVAIGSGIGGLPMIEHNHNALNRGGPRKISPFFVPGSIINMISGNLAIQHGFRGPNIAIT
TACTTGTHNIGYAARTIAYGDADAMVCGGAEMATTPLGLGGFSAARALSTRNDDPAAASRPWDRERDGFVLSDGAGVLVL
EEYEHAKRRGAPIYAELLGFGMSDDAYHMTAPNGSGAEMAMRNAVKDAGIEAGQLGYINAHGTSTQAGDVAESQAVERVM
GEAAKSVAVSSTKSMIGHLLGAAGAVEAIFSILAIRDQVAPPTINLDDPDEGCVLDYVPNTAREMAIDYTLSNSFGFGGT
NGSLIFGRT

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=419, Percent_Identity=45.8233890214797, Blast_Score=339, Evalue=4e-93,
Organism=Homo sapiens, GI223972627, Length=145, Percent_Identity=51.0344827586207, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI41872631, Length=424, Percent_Identity=26.6509433962264, Blast_Score=126, Evalue=5e-29,
Organism=Escherichia coli, GI1787337, Length=412, Percent_Identity=69.9029126213592, Blast_Score=554, Evalue=1e-159,
Organism=Escherichia coli, GI1788663, Length=412, Percent_Identity=40.0485436893204, Blast_Score=251, Evalue=7e-68,
Organism=Caenorhabditis elegans, GI71983541, Length=412, Percent_Identity=38.1067961165049, Blast_Score=258, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI71983535, Length=262, Percent_Identity=44.6564885496183, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI212642053, Length=422, Percent_Identity=24.4075829383886, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17550940, Length=410, Percent_Identity=22.4390243902439, Blast_Score=92, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320904, Length=453, Percent_Identity=37.3068432671082, Blast_Score=271, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24644341, Length=418, Percent_Identity=44.7368421052632, Blast_Score=331, Evalue=6e-91,
Organism=Drosophila melanogaster, GI19920632, Length=435, Percent_Identity=23.9080459770115, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI221330659, Length=435, Percent_Identity=23.9080459770115, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24581345, Length=429, Percent_Identity=22.8438228438228, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 42703; Mature: 42572

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRKRVVVTGLGLVTPVGNTVKESWDNILAGKSGISLIDQFDTSGFNTRFGGSVKDFDIS
CCCCEEEEEECCEECCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCC
PYLNPKDARKMDLFIQYGIAAAGQAIADAGLESNDDNADRIGVAIGSGIGGLPMIEHNHN
CCCCCCCCHHEEEEEEECHHHHCHHHHHCCCCCCCCCCCEEEEEECCCCCCCCEEECCCC
ALNRGGPRKISPFFVPGSIINMISGNLAIQHGFRGPNIAITTACTTGTHNIGYAARTIAY
HHCCCCCCCCCCEECCHHHHHHHCCCEEEEECCCCCCEEEEEEEECCCCCCCCEEEEEEE
GDADAMVCGGAEMATTPLGLGGFSAARALSTRNDDPAAASRPWDRERDGFVLSDGAGVLV
CCCCEEEECCCHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCEEE
LEEYEHAKRRGAPIYAELLGFGMSDDAYHMTAPNGSGAEMAMRNAVKDAGIEAGQLGYIN
ECCHHHHHHCCCCEEHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEE
AHGTSTQAGDVAESQAVERVMGEAAKSVAVSSTKSMIGHLLGAAGAVEAIFSILAIRDQV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APPTINLDDPDEGCVLDYVPNTAREMAIDYTLSNSFGFGGTNGSLIFGRT
CCCCCCCCCCCCCEEEECCCCCHHHEEEEEEECCCCCCCCCCCCEEEECC
>Mature Secondary Structure 
PRKRVVVTGLGLVTPVGNTVKESWDNILAGKSGISLIDQFDTSGFNTRFGGSVKDFDIS
CCCEEEEEECCEECCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCC
PYLNPKDARKMDLFIQYGIAAAGQAIADAGLESNDDNADRIGVAIGSGIGGLPMIEHNHN
CCCCCCCCHHEEEEEEECHHHHCHHHHHCCCCCCCCCCCEEEEEECCCCCCCCEEECCCC
ALNRGGPRKISPFFVPGSIINMISGNLAIQHGFRGPNIAITTACTTGTHNIGYAARTIAY
HHCCCCCCCCCCEECCHHHHHHHCCCEEEEECCCCCCEEEEEEEECCCCCCCCEEEEEEE
GDADAMVCGGAEMATTPLGLGGFSAARALSTRNDDPAAASRPWDRERDGFVLSDGAGVLV
CCCCEEEECCCHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCEEE
LEEYEHAKRRGAPIYAELLGFGMSDDAYHMTAPNGSGAEMAMRNAVKDAGIEAGQLGYIN
ECCHHHHHHCCCCEEHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEE
AHGTSTQAGDVAESQAVERVMGEAAKSVAVSSTKSMIGHLLGAAGAVEAIFSILAIRDQV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APPTINLDDPDEGCVLDYVPNTAREMAIDYTLSNSFGFGGTNGSLIFGRT
CCCCCCCCCCCCCEEEECCCCCHHHEEEEEEECCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]