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The map label for this gene is pabC [H]

Identifier: 92113728

GI number: 92113728

Start: 1824711

End: 1825526

Strand: Direct

Name: pabC [H]

Synonym: Csal_1604

Alternate gene names: 92113728

Gene position: 1824711-1825526 (Clockwise)

Preceding gene: 92113727

Following gene: 92113729

Centisome position: 49.36

GC content: 68.63

Gene sequence:

>816_bases
ATGGGTGACGAGGCGGTACCGTTCGATGATCGGGGCCTCGCTTACGGGGACGGTCTCTTCGAGACCGTCCTCGTGCGTGA
CGGGCAGCCTGTCCTGTGGCAAGCGCACATGGCGCGGCTGGCACGGGGAGCCGACCGCCTGGGGCTGCCCATGCCGGCGG
CCGAGACGTTGAACGCGCTGCCCGGGCGGGCGGAAGGTGGCCTGCAGGTGCTCAAGCTGCTCGTGACGCGCGGCAGTGGC
GGGCGCGGGTACGCCGTGCCCGATACGCCCAGGCCGCGTCTGCGCTGGCGTTTCTCCCCCTTCGCGCCCATGCCCCGGCG
ATGGCGCGAGGGCGTGCACGTGCGCCTGTGCCACCTGCGCCTCGGTCATCAGCCGCTGCTGGCCGGCATCAAGCATCTCA
ATCGTCTCGAGAACGTACTGGCGCGTCGCGAATGGCAGGCCCCCGAGATTGCCGAGGGCCTGCTCCGCGACCAGCAAGAT
CGCCTCGTCGAAGCGACCAGCATGAATCTGGTATGGCGACGTCACGGGCGGCTGGAAACGCCGTGCCTGACGGCATGCGG
CGTGGAAGGAACCCTGCTGTCGACCCTGCGCGAGCATTTGCCGATCCATGCCTGCGACGCGGGCATCGATGCCCTGATCG
AGGCCGAGGCGGCATGGGTGCTCAATTCGGTGCAAGGCGCCTGGCCACTGGCACGCCTGGACGATGCGCAAGGTGGCTGT
CTGAAGCGTTGGTCGATGGGTACCGAGCACAGGCAATTACAACGCCACGCCCAGGCGCTGCTGGGATATCCCGCGAGTGC
CCTGGGCGAGGCTTGA

Upstream 100 bases:

>100_bases
CCAACACGGCGCGCGAGATGGCCATCGACTACACCCTGTCGAACTCCTTCGGCTTCGGTGGTACCAACGGGTCACTGATC
TTCGGTCGTACCTGATCGCC

Downstream 100 bases:

>100_bases
AACAAGGTAGCGACATGCGAGTGGTCAAGATTTTATTGGGCGGGGCGGCGCTGGTGGGCGTGGCGGCATTCGGCGCCTAC
CAGTATTGGCAATCCCGGCT

Product: aminodeoxychorismate lyase apoprotein

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MGDEAVPFDDRGLAYGDGLFETVLVRDGQPVLWQAHMARLARGADRLGLPMPAAETLNALPGRAEGGLQVLKLLVTRGSG
GRGYAVPDTPRPRLRWRFSPFAPMPRRWREGVHVRLCHLRLGHQPLLAGIKHLNRLENVLARREWQAPEIAEGLLRDQQD
RLVEATSMNLVWRRHGRLETPCLTACGVEGTLLSTLREHLPIHACDAGIDALIEAEAAWVLNSVQGAWPLARLDDAQGGC
LKRWSMGTEHRQLQRHAQALLGYPASALGEA

Sequences:

>Translated_271_residues
MGDEAVPFDDRGLAYGDGLFETVLVRDGQPVLWQAHMARLARGADRLGLPMPAAETLNALPGRAEGGLQVLKLLVTRGSG
GRGYAVPDTPRPRLRWRFSPFAPMPRRWREGVHVRLCHLRLGHQPLLAGIKHLNRLENVLARREWQAPEIAEGLLRDQQD
RLVEATSMNLVWRRHGRLETPCLTACGVEGTLLSTLREHLPIHACDAGIDALIEAEAAWVLNSVQGAWPLARLDDAQGGC
LKRWSMGTEHRQLQRHAQALLGYPASALGEA
>Mature_270_residues
GDEAVPFDDRGLAYGDGLFETVLVRDGQPVLWQAHMARLARGADRLGLPMPAAETLNALPGRAEGGLQVLKLLVTRGSGG
RGYAVPDTPRPRLRWRFSPFAPMPRRWREGVHVRLCHLRLGHQPLLAGIKHLNRLENVLARREWQAPEIAEGLLRDQQDR
LVEATSMNLVWRRHGRLETPCLTACGVEGTLLSTLREHLPIHACDAGIDALIEAEAAWVLNSVQGAWPLARLDDAQGGCL
KRWSMGTEHRQLQRHAQALLGYPASALGEA

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=194, Percent_Identity=37.1134020618557, Blast_Score=111, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 29966; Mature: 29835

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDEAVPFDDRGLAYGDGLFETVLVRDGQPVLWQAHMARLARGADRLGLPMPAAETLNAL
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCHHCCCCCCHHHHHHCC
PGRAEGGLQVLKLLVTRGSGGRGYAVPDTPRPRLRWRFSPFAPMPRRWREGVHVRLCHLR
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHCCCEEEEEEHH
LGHQPLLAGIKHLNRLENVLARREWQAPEIAEGLLRDQQDRLVEATSMNLVWRRHGRLET
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PCLTACGVEGTLLSTLREHLPIHACDAGIDALIEAEAAWVLNSVQGAWPLARLDDAQGGC
CHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCH
LKRWSMGTEHRQLQRHAQALLGYPASALGEA
HHHHCCCHHHHHHHHHHHHHHCCCHHHHCCC
>Mature Secondary Structure 
GDEAVPFDDRGLAYGDGLFETVLVRDGQPVLWQAHMARLARGADRLGLPMPAAETLNAL
CCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCHHCCCCCCHHHHHHCC
PGRAEGGLQVLKLLVTRGSGGRGYAVPDTPRPRLRWRFSPFAPMPRRWREGVHVRLCHLR
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHCCCEEEEEEHH
LGHQPLLAGIKHLNRLENVLARREWQAPEIAEGLLRDQQDRLVEATSMNLVWRRHGRLET
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PCLTACGVEGTLLSTLREHLPIHACDAGIDALIEAEAAWVLNSVQGAWPLARLDDAQGGC
CHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCH
LKRWSMGTEHRQLQRHAQALLGYPASALGEA
HHHHCCCHHHHHHHHHHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]