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The map label for this gene is dhmA [H]

Identifier: 92112313

GI number: 92112313

Start: 201842

End: 202813

Strand: Direct

Name: dhmA [H]

Synonym: Csal_0178

Alternate gene names: 92112313

Gene position: 201842-202813 (Clockwise)

Preceding gene: 92112311

Following gene: 92112321

Centisome position: 5.46

GC content: 62.86

Gene sequence:

>972_bases
ATGACGACTGACAGCCTGACCACCGTCAGCGCCTCGGAAACGCGCGGCGACCATGCGCCTGGTGGGCGAGCGTCGGCAGC
GCCGCAGGTCCACTACCGCGTCGAGCAGGTGGGCGACGTCAAGGTGTTCTATCGGGAAGCGGGAGACCCGGCGGCACCAG
CGGTGCTGCTGCTGCACGGGTTCGCGGCCTCGTCGTACATGTGGCGCGATGTGATCGAGGCGCTCGCGGACGGCTATCAC
GTGATCGCCCCGGATCTGCCCGCTTTTGGCTACACGGAGGCACCGGCACGCGGCCAGTACGATTACACCTTCGCCAACCT
GACGAAAACGATCGAGCGATTCACCGACCAGTTGAAGCTCACCCGCTATGCGATGGCGGTGCACGACTATGGCGCGCCGG
TGGGGTGGCGCTTGGCACTCGCCCACCCGTCAAGGATAACGGCGATCATTTCGCAAAACGGCAACGCGTACGAGGAGGGC
CTTTCCGCCGGCTGGGAGCCCATCCGGAAATACTGGAATGACCCGACGGCGGAAAATCGGCAAGCGCTCAGCGACTTCCC
GACACCGGCGTCCATCAAGTGGCAGTACGTGGAAGGAGTCAGCGACACGAGCCTCGTGGCGCCGGATGCCTATACGCTGG
AAGGTGCCCAGATCTTGCGCCCGGGCATGGCGGATATTCAGCTCGATCTATTGCTGGATTACGCCACCAATGTCGAGCAA
TACCCAGCGTTTCAGGCCTATTTCCGCGAGTATCAGCCGCCGCTTCTTGCCGTCTGGGGGGAGCACGATCCGTTCTTCCT
GCCGCCCGGTGCCGAGGCATGGAAGCGGGATATCCCCGATGCCGACATTCGCCTTTACGACACGGGGCACTTCGCTCTGG
AAACCCACAGCGAGGTGATCATCCCGACCATTCGCCAGTTCCTGGATGACCACGTGAGTCTCCATAGGCAAGAGGGGGCT
CATGCAAAATAG

Upstream 100 bases:

>100_bases
TGAACTCATCTTTGTAACCCTTTAAATGTATGTTGACAGGTTACTATGGGGCTGTATAACCTTCAAATGCACAATTTGAT
GGTTACCAAGGAGTTCGATC

Downstream 100 bases:

>100_bases
CGTGCATGAAACAAATCGCCCGTGGTCCAGGCCACGGGCGATGGGGTCATGGCGCCGGATGGCGCCTGACGAGGCGGATC
ATCGGCAGAAGCTCATTTCT

Product: alpha/beta hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MTTDSLTTVSASETRGDHAPGGRASAAPQVHYRVEQVGDVKVFYREAGDPAAPAVLLLHGFAASSYMWRDVIEALADGYH
VIAPDLPAFGYTEAPARGQYDYTFANLTKTIERFTDQLKLTRYAMAVHDYGAPVGWRLALAHPSRITAIISQNGNAYEEG
LSAGWEPIRKYWNDPTAENRQALSDFPTPASIKWQYVEGVSDTSLVAPDAYTLEGAQILRPGMADIQLDLLLDYATNVEQ
YPAFQAYFREYQPPLLAVWGEHDPFFLPPGAEAWKRDIPDADIRLYDTGHFALETHSEVIIPTIRQFLDDHVSLHRQEGA
HAK

Sequences:

>Translated_323_residues
MTTDSLTTVSASETRGDHAPGGRASAAPQVHYRVEQVGDVKVFYREAGDPAAPAVLLLHGFAASSYMWRDVIEALADGYH
VIAPDLPAFGYTEAPARGQYDYTFANLTKTIERFTDQLKLTRYAMAVHDYGAPVGWRLALAHPSRITAIISQNGNAYEEG
LSAGWEPIRKYWNDPTAENRQALSDFPTPASIKWQYVEGVSDTSLVAPDAYTLEGAQILRPGMADIQLDLLLDYATNVEQ
YPAFQAYFREYQPPLLAVWGEHDPFFLPPGAEAWKRDIPDADIRLYDTGHFALETHSEVIIPTIRQFLDDHVSLHRQEGA
HAK
>Mature_322_residues
TTDSLTTVSASETRGDHAPGGRASAAPQVHYRVEQVGDVKVFYREAGDPAAPAVLLLHGFAASSYMWRDVIEALADGYHV
IAPDLPAFGYTEAPARGQYDYTFANLTKTIERFTDQLKLTRYAMAVHDYGAPVGWRLALAHPSRITAIISQNGNAYEEGL
SAGWEPIRKYWNDPTAENRQALSDFPTPASIKWQYVEGVSDTSLVAPDAYTLEGAQILRPGMADIQLDLLLDYATNVEQY
PAFQAYFREYQPPLLAVWGEHDPFFLPPGAEAWKRDIPDADIRLYDTGHFALETHSEVIIPTIRQFLDDHVSLHRQEGAH
AK

Specific function: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the haloalkane dehalogenase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=115, Percent_Identity=38.2608695652174, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI218777837, Length=139, Percent_Identity=29.4964028776978, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562298, Length=292, Percent_Identity=23.6301369863014, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324392, Length=270, Percent_Identity=48.1481481481481, Blast_Score=250, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.5 [H]

Molecular weight: Translated: 35951; Mature: 35820

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDSLTTVSASETRGDHAPGGRASAAPQVHYRVEQVGDVKVFYREAGDPAAPAVLLLHG
CCCCCCEEEECCCCCCCCCCCCCCCCCCHHEEHHHHCCCEEEEEECCCCCCCCHHHHHHH
FAASSYMWRDVIEALADGYHVIAPDLPAFGYTEAPARGQYDYTFANLTKTIERFTDQLKL
HHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TRYAMAVHDYGAPVGWRLALAHPSRITAIISQNGNAYEEGLSAGWEPIRKYWNDPTAENR
HHHHHHHHHCCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHCCCHHHHHHCCCCCCCHH
QALSDFPTPASIKWQYVEGVSDTSLVAPDAYTLEGAQILRPGMADIQLDLLLDYATNVEQ
HHHHCCCCCCCEEEEEECCCCCCCEECCCCEEECCHHHHCCCCCCEEHEEHHHHHCCHHH
YPAFQAYFREYQPPLLAVWGEHDPFFLPPGAEAWKRDIPDADIRLYDTGHFALETHSEVI
CHHHHHHHHHCCCCEEEEECCCCCEEECCCHHHHHHCCCCCCEEEEECCCEEEECCCCCH
IPTIRQFLDDHVSLHRQEGAHAK
HHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTDSLTTVSASETRGDHAPGGRASAAPQVHYRVEQVGDVKVFYREAGDPAAPAVLLLHG
CCCCCEEEECCCCCCCCCCCCCCCCCCHHEEHHHHCCCEEEEEECCCCCCCCHHHHHHH
FAASSYMWRDVIEALADGYHVIAPDLPAFGYTEAPARGQYDYTFANLTKTIERFTDQLKL
HHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TRYAMAVHDYGAPVGWRLALAHPSRITAIISQNGNAYEEGLSAGWEPIRKYWNDPTAENR
HHHHHHHHHCCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHCCCHHHHHHCCCCCCCHH
QALSDFPTPASIKWQYVEGVSDTSLVAPDAYTLEGAQILRPGMADIQLDLLLDYATNVEQ
HHHHCCCCCCCEEEEEECCCCCCCEECCCCEEECCHHHHCCCCCCEEHEEHHHHHCCHHH
YPAFQAYFREYQPPLLAVWGEHDPFFLPPGAEAWKRDIPDADIRLYDTGHFALETHSEVI
CHHHHHHHHHCCCCEEEEECCCCCEEECCCHHHHHHCCCCCCEEEEECCCEEEECCCCCH
IPTIRQFLDDHVSLHRQEGAHAK
HHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA