| Definition | Chromohalobacter salexigens DSM 3043 chromosome, complete genome. |
|---|---|
| Accession | NC_007963 |
| Length | 3,696,649 |
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The map label for this gene is pldh-t [H]
Identifier: 92112268
GI number: 92112268
Start: 154514
End: 155284
Strand: Direct
Name: pldh-t [H]
Synonym: Csal_0133
Alternate gene names: 92112268
Gene position: 154514-155284 (Clockwise)
Preceding gene: 92112267
Following gene: 92112269
Centisome position: 4.18
GC content: 66.41
Gene sequence:
>771_bases ATGCGTAGCGGGCTGGCCGGTAAACGTGTGTTGATCACGGGGGCGGCGCGTGGCCTGGGCCGCAGCATTGCCGAGGCCGC GGCCGAGCAGGGCGCGCGCCTGGTGCTCAGCGATATCCTGACCGAGGAGCTGGCGCAGGTCGCCGAGAGCCTGCGCGAGC GAGGCGCGGATGTCGAGACACAGCCCATGGACCAGGGCGACGAGGATTCCATTCGCAACGCGATGGCGGCGATTGGAGCG GGCGGCGCGCTGGACGGCCTGGTGAACAATGCGGCATTGGCGACCCAGGTCGGCGGCAAGACCCTGGTCGATTACGACCC GGCGCTCTGGGACCGTGTCATGCGCATCAACGTACGCGGTCTGTGGCTGGTGACCCGCGAGGCGATACCGCTGCTTTCTC GTGAGGCCGATGCCGGCTCGGCCCGTGCCAAGATCGTCAACCTGGCATCCGATACCGCGTTGTGGGGCGCACCTCGTTTG ATGGCCTATGTCGCCAGTAAAGGCGCGGTGATCGCGATGACGCGCTCGATGGCGCGCGAGCTGGGCGAACAGGGGATCTG CGTCAATGCCATTGCCCCGGGCTTGACGCATTGCGAGGCGACGGAATACGTGCCCGCCGAACGTTATGCCCACTATGCCG CTGGCCGCGCGTTACCGGCCGAGCAGCAGCCGGGGGATATCGATGGCACCGTGCTCTATCTATTGTCCGAGTGGTCCGAC TTCGTGACGGGCCAGCTGATTCCCGTCAATGGCGGATTCGTGTGTCGCTGA
Upstream 100 bases:
>100_bases GAAAACCTGTATCAGCATGACGTCGGCCTCTCGCGGTTGCGCCGGGTCATGCGCAAGGCGGCCAAGCAGCAATTGTCGCG GCGCCAGGAGGTTGCCTGAC
Downstream 100 bases:
>100_bases AACAAGCGCGAACGCAGGAGAGAGAGATGGCCGACGACGAGACGCGCAAGTACGTGATTCCCGGGCTGGAGCGTGGCCTG ACGATTCTCATGGCCTTGAG
Product: short chain dehydrogenase
Products: NA
Alternate protein names: tPLDH [H]
Number of amino acids: Translated: 256; Mature: 256
Protein sequence:
>256_residues MRSGLAGKRVLITGAARGLGRSIAEAAAEQGARLVLSDILTEELAQVAESLRERGADVETQPMDQGDEDSIRNAMAAIGA GGALDGLVNNAALATQVGGKTLVDYDPALWDRVMRINVRGLWLVTREAIPLLSREADAGSARAKIVNLASDTALWGAPRL MAYVASKGAVIAMTRSMARELGEQGICVNAIAPGLTHCEATEYVPAERYAHYAAGRALPAEQQPGDIDGTVLYLLSEWSD FVTGQLIPVNGGFVCR
Sequences:
>Translated_256_residues MRSGLAGKRVLITGAARGLGRSIAEAAAEQGARLVLSDILTEELAQVAESLRERGADVETQPMDQGDEDSIRNAMAAIGA GGALDGLVNNAALATQVGGKTLVDYDPALWDRVMRINVRGLWLVTREAIPLLSREADAGSARAKIVNLASDTALWGAPRL MAYVASKGAVIAMTRSMARELGEQGICVNAIAPGLTHCEATEYVPAERYAHYAAGRALPAEQQPGDIDGTVLYLLSEWSD FVTGQLIPVNGGFVCR >Mature_256_residues MRSGLAGKRVLITGAARGLGRSIAEAAAEQGARLVLSDILTEELAQVAESLRERGADVETQPMDQGDEDSIRNAMAAIGA GGALDGLVNNAALATQVGGKTLVDYDPALWDRVMRINVRGLWLVTREAIPLLSREADAGSARAKIVNLASDTALWGAPRL MAYVASKGAVIAMTRSMARELGEQGICVNAIAPGLTHCEATEYVPAERYAHYAAGRALPAEQQPGDIDGTVLYLLSEWSD FVTGQLIPVNGGFVCR
Specific function: Involved in the degradation of pyridoxine or pyridoxamine (free, phosphate-unbound, forms of vitamin B6). Oxidizes pyridoxal to 4-pyridoxolactone, but does not have activity toward pyridoxal 5'-phosphate, pyridoxine, pyridoxamine, pyridoxamine 5'-phosphat
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=29.4573643410853, Blast_Score=100, Evalue=9e-22, Organism=Homo sapiens, GI7705925, Length=255, Percent_Identity=29.4117647058824, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI15277342, Length=264, Percent_Identity=28.030303030303, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI4758504, Length=224, Percent_Identity=33.9285714285714, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI31542939, Length=215, Percent_Identity=28.8372093023256, Blast_Score=75, Evalue=8e-14, Organism=Homo sapiens, GI5031737, Length=254, Percent_Identity=25.1968503937008, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI142976729, Length=214, Percent_Identity=27.1028037383178, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI66933014, Length=257, Percent_Identity=26.8482490272374, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI19923817, Length=268, Percent_Identity=26.1194029850746, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI4504505, Length=198, Percent_Identity=30.8080808080808, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI126723750, Length=262, Percent_Identity=24.4274809160305, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI126723191, Length=191, Percent_Identity=29.3193717277487, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI33667109, Length=205, Percent_Identity=26.3414634146341, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI83715985, Length=184, Percent_Identity=34.2391304347826, Blast_Score=64, Evalue=9e-11, Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=32.6771653543307, Blast_Score=114, Evalue=6e-27, Organism=Escherichia coli, GI1789208, Length=255, Percent_Identity=30.5882352941176, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=30.8300395256917, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=31.1538461538462, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=28.6821705426357, Blast_Score=91, Evalue=5e-20, Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=28.6852589641434, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=30.6451612903226, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=31.1023622047244, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI2367365, Length=253, Percent_Identity=28.4584980237154, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1788459, Length=258, Percent_Identity=26.7441860465116, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=27.2030651340996, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1787526, Length=252, Percent_Identity=30.1587301587302, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=28.8537549407115, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=30.0751879699248, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=28.6852589641434, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17560220, Length=270, Percent_Identity=30, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17538182, Length=202, Percent_Identity=34.6534653465347, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17561402, Length=261, Percent_Identity=26.8199233716475, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=29.6296296296296, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=27.3809523809524, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI115534694, Length=269, Percent_Identity=26.7657992565056, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=27.9527559055118, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17559104, Length=273, Percent_Identity=28.9377289377289, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=25, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI193204405, Length=273, Percent_Identity=28.2051282051282, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=27.0676691729323, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17562904, Length=270, Percent_Identity=26.2962962962963, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=27.6515151515151, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI193203115, Length=182, Percent_Identity=31.3186813186813, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI193203117, Length=178, Percent_Identity=31.4606741573034, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI72000259, Length=272, Percent_Identity=27.2058823529412, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17555612, Length=216, Percent_Identity=29.6296296296296, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17508895, Length=201, Percent_Identity=26.3681592039801, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17564282, Length=205, Percent_Identity=29.2682926829268, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17562990, Length=273, Percent_Identity=26.7399267399267, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI86565303, Length=214, Percent_Identity=28.9719626168224, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI71997099, Length=206, Percent_Identity=30.5825242718447, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17560150, Length=275, Percent_Identity=26.9090909090909, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17536651, Length=270, Percent_Identity=26.6666666666667, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=24.3445692883895, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17538480, Length=275, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17551412, Length=207, Percent_Identity=28.5024154589372, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17536025, Length=261, Percent_Identity=27.2030651340996, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17563726, Length=273, Percent_Identity=26.3736263736264, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17568967, Length=198, Percent_Identity=26.7676767676768, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=254, Percent_Identity=26.7716535433071, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=30.078125, Blast_Score=107, Evalue=1e-23, Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=32.4324324324324, Blast_Score=97, Evalue=9e-21, Organism=Drosophila melanogaster, GI17737361, Length=224, Percent_Identity=35.7142857142857, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI28571526, Length=259, Percent_Identity=30.8880308880309, Blast_Score=92, Evalue=5e-19, Organism=Drosophila melanogaster, GI23397609, Length=255, Percent_Identity=28.6274509803922, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=28.2352941176471, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI21357673, Length=200, Percent_Identity=31, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI24643142, Length=261, Percent_Identity=30.6513409961686, Blast_Score=84, Evalue=6e-17, Organism=Drosophila melanogaster, GI24644337, Length=178, Percent_Identity=34.2696629213483, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=29.3650793650794, Blast_Score=78, Evalue=7e-15, Organism=Drosophila melanogaster, GI21358495, Length=200, Percent_Identity=30, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI24584744, Length=203, Percent_Identity=27.0935960591133, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI28574402, Length=203, Percent_Identity=27.0935960591133, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.107 [H]
Molecular weight: Translated: 27001; Mature: 27001
Theoretical pI: Translated: 4.74; Mature: 4.74
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRSGLAGKRVLITGAARGLGRSIAEAAAEQGARLVLSDILTEELAQVAESLRERGADVET CCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC QPMDQGDEDSIRNAMAAIGAGGALDGLVNNAALATQVGGKTLVDYDPALWDRVMRINVRG CCCCCCCHHHHHHHHHHHCCCHHHHHHHCCHHHHHHCCCCEEECCCHHHHHHHHHCCCCE LWLVTREAIPLLSREADAGSARAKIVNLASDTALWGAPRLMAYVASKGAVIAMTRSMARE EEEEHHHHHHHHHCCCCCCCCHHEEEECCCCCHHHCHHHHHHHHHCCCCEEEHHHHHHHH LGEQGICVNAIAPGLTHCEATEYVPAERYAHYAAGRALPAEQQPGDIDGTVLYLLSEWSD HCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH FVTGQLIPVNGGFVCR HHCCEEEECCCCEEEC >Mature Secondary Structure MRSGLAGKRVLITGAARGLGRSIAEAAAEQGARLVLSDILTEELAQVAESLRERGADVET CCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC QPMDQGDEDSIRNAMAAIGAGGALDGLVNNAALATQVGGKTLVDYDPALWDRVMRINVRG CCCCCCCHHHHHHHHHHHCCCHHHHHHHCCHHHHHHCCCCEEECCCHHHHHHHHHCCCCE LWLVTREAIPLLSREADAGSARAKIVNLASDTALWGAPRLMAYVASKGAVIAMTRSMARE EEEEHHHHHHHHHCCCCCCCCHHEEEECCCCCHHHCHHHHHHHHHCCCCEEEHHHHHHHH LGEQGICVNAIAPGLTHCEATEYVPAERYAHYAAGRALPAEQQPGDIDGTVLYLLSEWSD HCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH FVTGQLIPVNGGFVCR HHCCEEEECCCCEEEC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11214968 [H]