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The map label for this gene is trxC [C]

Identifier: 91789225

GI number: 91789225

Start: 3563070

End: 3563507

Strand: Direct

Name: trxC [C]

Synonym: Bpro_3369

Alternate gene names: 91789225

Gene position: 3563070-3563507 (Clockwise)

Preceding gene: 91789220

Following gene: 91789226

Centisome position: 68.52

GC content: 66.89

Gene sequence:

>438_bases
ATGACTGAATCACTCCACATTGTTTGCCCGCACTGCCACACCACCAACCGCGTCCGGGCAGACCAGCTTGGCAGTGCGCC
CGACTGCGGCAGCTGCAAGAAGGCGCTGTTCACCGCCCATTCCACCGCGCTGGACGAAGCCGCCTTTGACAAACACATCG
GCCGCAACCACATTCCGGTGCTGGTGGACTTCTGGGCGCCGTGGTGCGGGCCCTGCCGCCAGATGGCGCCGGCCTACGAA
CAGGTGGCCGCGCAGCTGGAGCCCCGGGTGCGCGTGGCCAAGGTAGACACCGAAGCCGTGCCCAACCTGGGGGCACGTTT
CAACATTCGCAGCATTCCCACGCTGGCGCTGTTTCAGAACGGTCGCGAGGTGGCGCGCCAGGCCGGCGCCATGGGCGCGG
CAGACATCGTGCGCTGGGTGCAGTCCAAGCTGCGCTGA

Upstream 100 bases:

>100_bases
TGCAAATCGCGGGCGGTGGCCGGCAGGACGGGTGCCGGCGCCAGCCGAATCAACGGGAAAATGCTTGAAATGCCCCGCCA
CGGCCCCAAGGTGCACCCTT

Downstream 100 bases:

>100_bases
TGGGGGTCTGCCCAGAAATGCTATTTTTTCAATAGCACTTCACCCTTTGCTTGATTGGACTGCCGGCACTTTTTATTCAT
AAAACTGCCAACCCAGCTCA

Product: thioredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MTESLHIVCPHCHTTNRVRADQLGSAPDCGSCKKALFTAHSTALDEAAFDKHIGRNHIPVLVDFWAPWCGPCRQMAPAYE
QVAAQLEPRVRVAKVDTEAVPNLGARFNIRSIPTLALFQNGREVARQAGAMGAADIVRWVQSKLR

Sequences:

>Translated_145_residues
MTESLHIVCPHCHTTNRVRADQLGSAPDCGSCKKALFTAHSTALDEAAFDKHIGRNHIPVLVDFWAPWCGPCRQMAPAYE
QVAAQLEPRVRVAKVDTEAVPNLGARFNIRSIPTLALFQNGREVARQAGAMGAADIVRWVQSKLR
>Mature_144_residues
TESLHIVCPHCHTTNRVRADQLGSAPDCGSCKKALFTAHSTALDEAAFDKHIGRNHIPVLVDFWAPWCGPCRQMAPAYEQ
VAAQLEPRVRVAKVDTEAVPNLGARFNIRSIPTLALFQNGREVARQAGAMGAADIVRWVQSKLR

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758304, Length=101, Percent_Identity=36.6336633663366, Blast_Score=73, Evalue=7e-14,
Organism=Homo sapiens, GI20070125, Length=92, Percent_Identity=35.8695652173913, Blast_Score=73, Evalue=8e-14,
Organism=Homo sapiens, GI224493972, Length=106, Percent_Identity=33.0188679245283, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI42794771, Length=106, Percent_Identity=33.0188679245283, Blast_Score=71, Evalue=3e-13,
Organism=Homo sapiens, GI21361657, Length=78, Percent_Identity=41.025641025641, Blast_Score=70, Evalue=9e-13,
Organism=Homo sapiens, GI5031973, Length=98, Percent_Identity=33.6734693877551, Blast_Score=66, Evalue=8e-12,
Organism=Homo sapiens, GI94966757, Length=95, Percent_Identity=36.8421052631579, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1788936, Length=140, Percent_Identity=41.4285714285714, Blast_Score=124, Evalue=3e-30,
Organism=Escherichia coli, GI87082331, Length=101, Percent_Identity=34.6534653465347, Blast_Score=87, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI25144092, Length=101, Percent_Identity=37.6237623762376, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17554386, Length=103, Percent_Identity=35.9223300970874, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17556044, Length=104, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193209454, Length=103, Percent_Identity=33.9805825242718, Blast_Score=72, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17569137, Length=103, Percent_Identity=33.9805825242718, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32566189, Length=103, Percent_Identity=33.9805825242718, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17507915, Length=101, Percent_Identity=34.6534653465347, Blast_Score=69, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI115532378, Length=89, Percent_Identity=35.9550561797753, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115532380, Length=89, Percent_Identity=35.9550561797753, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17544108, Length=89, Percent_Identity=34.8314606741573, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323072, Length=86, Percent_Identity=39.5348837209302, Blast_Score=75, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6321648, Length=86, Percent_Identity=36.046511627907, Blast_Score=67, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17647799, Length=98, Percent_Identity=40.8163265306122, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573567, Length=93, Percent_Identity=35.4838709677419, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19921434, Length=104, Percent_Identity=35.5769230769231, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21358065, Length=135, Percent_Identity=28.8888888888889, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17648013, Length=71, Percent_Identity=38.0281690140845, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583090, Length=71, Percent_Identity=38.0281690140845, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI18859803, Length=127, Percent_Identity=30.7086614173228, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 15927; Mature: 15796

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESLHIVCPHCHTTNRVRADQLGSAPDCGSCKKALFTAHSTALDEAAFDKHIGRNHIPV
CCCCCEEEECCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
LVDFWAPWCGPCRQMAPAYEQVAAQLEPRVRVAKVDTEAVPNLGARFNIRSIPTLALFQN
EEECCCCCCCHHHHHCHHHHHHHHHHCCCEEEEECCHHHCCCCCCEEECCCCCHHHHHHC
GREVARQAGAMGAADIVRWVQSKLR
CHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TESLHIVCPHCHTTNRVRADQLGSAPDCGSCKKALFTAHSTALDEAAFDKHIGRNHIPV
CCCCEEEECCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
LVDFWAPWCGPCRQMAPAYEQVAAQLEPRVRVAKVDTEAVPNLGARFNIRSIPTLALFQN
EEECCCCCCCHHHHHCHHHHHHHHHHCCCEEEEECCHHHCCCCCCEEECCCCCHHHHHHC
GREVARQAGAMGAADIVRWVQSKLR
CHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8652661 [H]