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The map label for this gene is nuoH

Identifier: 91789109

GI number: 91789109

Start: 3439066

End: 3440145

Strand: Reverse

Name: nuoH

Synonym: Bpro_3249

Alternate gene names: 91789109

Gene position: 3440145-3439066 (Counterclockwise)

Preceding gene: 91789110

Following gene: 91789108

Centisome position: 66.15

GC content: 57.59

Gene sequence:

>1080_bases
ATGATCGATACGGTATATGGTTTTGGCCAGGGCTTGATGGGTGGCATCTGGCCGGCGACGGTCTGGCCCGTGCTCTGGGC
GCTCATCAAGATTGTCTGTGTCCTGCTGCCGCTGATGGGCTGTGTGGCCTACCTCACCTTGTGGGAGCGCAAGGCCATCG
GTTTTACCCAGATTCGCTTCGGCCCCAATCGCGTCGGTCCCTTCGGCCTGCTGCAGCCGATTGCCGATGCGCTCAAGCTG
CTGACCAAAGAGATCATCATGCCGACGGCGGCCAGCAAAGGCCTGTTTGTATTGGGCCCCATCATGACCATCATGCCGGC
ACTGGCCGCATGGGCGGTGATTCCTTTTGGCCCCGACATTGCACTGTCCAACATCAATGCTGGCCTGCTGTTCCTGATGG
CCATCACCTCGATGGAGGTGTACGGCGTGATCATTGCGGGCTGGGCCTCGAATTCCAAATACGCGTTTCTGGGCGCCATG
CGCGCTTCGGCGCAAATGGTGAGCTACGAGATCGCCATGGGTTTCTGTCTGGTGGTGGTGCTGATGGTCTCAGCCAGTCT
GAACATGACCGACATCGTGATGAGCCAGGCCAAAGGTATCGCTGTCGGTTATGGCCTGAATTTCCTGTCCTGGAATTGGT
TGCCGCTGCTGCCGATTTTTGTCGTGTATTTCATCTCCGGGCTGGCCGAAACCAATCGTCATCCGTTTGACGTGGTTGAG
GGCGAGTCGGAAATTGTGGCGGGCCATATGGTCGAGTATTCGGGCATGGCCTTTGCCATGTTCTTCCTGGCCGAGTACGC
CAACATGTGGCTGGTCGCCATCCTGGCCGTCATTCTTTTCCTGGGCGGCTGGTTGTCGCCAGTGGACTGGTGGCTGTTCA
ATTTGATTCCAGGCTGGATCTGGTTGGGTGCCAAAACCTTTGTCGTCGTCACCATGTTCCTCTGGGTGCGCGCTACCTTC
CCACGCTTCCGTTACGACCAGATCATGCGTCTGGGCTGGAAGATCTTCATACCTGTGACCCTGGTCTGGCTGGTGGTCGT
TGGGGCCTGGATGCAGACCCCCTACAACATCTGGAAATAA

Upstream 100 bases:

>100_bases
ATCAGCTGGACGGACTGGTCCGGCGCGCCACGTCGTTGCAGCTGACAGCCGATGCGCGGCAGGGTGCCGGGCTGCAATCC
AGGCTGGAAGGAGCAGGCGC

Downstream 100 bases:

>100_bases
CATGAGCCCCCACGTTCGCTCACTTCGTGTAGCTCTCTGCCCCCCCCGGGGGGCGCTGCGCCTGCGGCCCGGCAAAGCCG
GTTCCGCGGCCCCTGCTTGC

Product: respiratory-chain NADH dehydrogenase subunit 1

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MIDTVYGFGQGLMGGIWPATVWPVLWALIKIVCVLLPLMGCVAYLTLWERKAIGFTQIRFGPNRVGPFGLLQPIADALKL
LTKEIIMPTAASKGLFVLGPIMTIMPALAAWAVIPFGPDIALSNINAGLLFLMAITSMEVYGVIIAGWASNSKYAFLGAM
RASAQMVSYEIAMGFCLVVVLMVSASLNMTDIVMSQAKGIAVGYGLNFLSWNWLPLLPIFVVYFISGLAETNRHPFDVVE
GESEIVAGHMVEYSGMAFAMFFLAEYANMWLVAILAVILFLGGWLSPVDWWLFNLIPGWIWLGAKTFVVVTMFLWVRATF
PRFRYDQIMRLGWKIFIPVTLVWLVVVGAWMQTPYNIWK

Sequences:

>Translated_359_residues
MIDTVYGFGQGLMGGIWPATVWPVLWALIKIVCVLLPLMGCVAYLTLWERKAIGFTQIRFGPNRVGPFGLLQPIADALKL
LTKEIIMPTAASKGLFVLGPIMTIMPALAAWAVIPFGPDIALSNINAGLLFLMAITSMEVYGVIIAGWASNSKYAFLGAM
RASAQMVSYEIAMGFCLVVVLMVSASLNMTDIVMSQAKGIAVGYGLNFLSWNWLPLLPIFVVYFISGLAETNRHPFDVVE
GESEIVAGHMVEYSGMAFAMFFLAEYANMWLVAILAVILFLGGWLSPVDWWLFNLIPGWIWLGAKTFVVVTMFLWVRATF
PRFRYDQIMRLGWKIFIPVTLVWLVVVGAWMQTPYNIWK
>Mature_359_residues
MIDTVYGFGQGLMGGIWPATVWPVLWALIKIVCVLLPLMGCVAYLTLWERKAIGFTQIRFGPNRVGPFGLLQPIADALKL
LTKEIIMPTAASKGLFVLGPIMTIMPALAAWAVIPFGPDIALSNINAGLLFLMAITSMEVYGVIIAGWASNSKYAFLGAM
RASAQMVSYEIAMGFCLVVVLMVSASLNMTDIVMSQAKGIAVGYGLNFLSWNWLPLLPIFVVYFISGLAETNRHPFDVVE
GESEIVAGHMVEYSGMAFAMFFLAEYANMWLVAILAVILFLGGWLSPVDWWLFNLIPGWIWLGAKTFVVVTMFLWVRATF
PRFRYDQIMRLGWKIFIPVTLVWLVVVGAWMQTPYNIWK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family

Homologues:

Organism=Homo sapiens, GI251831107, Length=305, Percent_Identity=41.3114754098361, Blast_Score=243, Evalue=2e-64,
Organism=Escherichia coli, GI1788618, Length=326, Percent_Identity=41.4110429447853, Blast_Score=258, Evalue=4e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOH_POLSJ (Q127X9)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_550061.1
- STRING:   Q127X9
- GeneID:   4014095
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_3249
- NMPDR:   fig|296591.1.peg.1189
- eggNOG:   COG1005
- HOGENOM:   HBG727670
- OMA:   FMVEYGS
- PhylomeDB:   Q127X9
- ProtClustDB:   CLSK723583
- BioCyc:   PSP296591:BPRO_3249-MONOMER
- HAMAP:   MF_01350
- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086
- PANTHER:   PTHR11432

Pfam domain/function: PF00146 NADHdh

EC number: =1.6.99.5

Molecular weight: Translated: 39950; Mature: 39950

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS00667 COMPLEX1_ND1_1; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x148ab5d0)-; HASH(0xaea8714)-; HASH(0xaea9284)-; HASH(0xaea8948)-; HASH(0x15a0990c)-; HASH(0x15888d18)-; HASH(0xaea8bd0)-; HASH(0xaea875c)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDTVYGFGQGLMGGIWPATVWPVLWALIKIVCVLLPLMGCVAYLTLWERKAIGFTQIRF
CCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
GPNRVGPFGLLQPIADALKLLTKEIIMPTAASKGLFVLGPIMTIMPALAAWAVIPFGPDI
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCC
ALSNINAGLLFLMAITSMEVYGVIIAGWASNSKYAFLGAMRASAQMVSYEIAMGFCLVVV
EECCCCHHHHHHHHHHHHHHHEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
LMVSASLNMTDIVMSQAKGIAVGYGLNFLSWNWLPLLPIFVVYFISGLAETNRHPFDVVE
HHHHCCCCHHHHHHHHCCCEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEC
GESEIVAGHMVEYSGMAFAMFFLAEYANMWLVAILAVILFLGGWLSPVDWWLFNLIPGWI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
WLGAKTFVVVTMFLWVRATFPRFRYDQIMRLGWKIFIPVTLVWLVVVGAWMQTPYNIWK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
>Mature Secondary Structure
MIDTVYGFGQGLMGGIWPATVWPVLWALIKIVCVLLPLMGCVAYLTLWERKAIGFTQIRF
CCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
GPNRVGPFGLLQPIADALKLLTKEIIMPTAASKGLFVLGPIMTIMPALAAWAVIPFGPDI
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCC
ALSNINAGLLFLMAITSMEVYGVIIAGWASNSKYAFLGAMRASAQMVSYEIAMGFCLVVV
EECCCCHHHHHHHHHHHHHHHEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
LMVSASLNMTDIVMSQAKGIAVGYGLNFLSWNWLPLLPIFVVYFISGLAETNRHPFDVVE
HHHHCCCCHHHHHHHHCCCEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEC
GESEIVAGHMVEYSGMAFAMFFLAEYANMWLVAILAVILFLGGWLSPVDWWLFNLIPGWI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
WLGAKTFVVVTMFLWVRATFPRFRYDQIMRLGWKIFIPVTLVWLVVVGAWMQTPYNIWK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA