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The map label for this gene is nuoI [H]

Identifier: 91789108

GI number: 91789108

Start: 3438425

End: 3438922

Strand: Reverse

Name: nuoI [H]

Synonym: Bpro_3248

Alternate gene names: 91789108

Gene position: 3438922-3438425 (Counterclockwise)

Preceding gene: 91789109

Following gene: 91789107

Centisome position: 66.13

GC content: 57.43

Gene sequence:

>498_bases
ATGTCTACCGTAGCCTCCGTCAAGGATTTTGTTTCGAGCTTCATGCTCACCGAGCTGTTCAAGGGCATGGCCCTGACCGG
CAAGTACATGTTCAGCCGCAAGATCACGGTCCAGTTTCCCGAAGAGAAAACCCCGCTGAGCCCGCGTTTTCGAGGGCTTC
ACGCCTTGCGCCGCTATGACAACGGCGAAGAGCGCTGCATTGCCTGCAAGCTCTGCGAAGCCGTGTGCCCGGCGCTGGCC
ATCACAATCGAGTCTGAAGTGCGTGACGACGGCAGCCGCCGCACCTCGCGTTACGACATTGACCTGACCAAATGCATTTT
TTGCGGCTTCTGTGAGGAAGCCTGCCCGGTCGACGCGATTGTCGAGACCCATATTTTTGAATACCACGGTGAAAAGCGCG
GTGACCTGTATTTCACCAAGGAGATGTTGCTGGCAGTGGGCGACCGCTACGAGGCCGAAATTGCCGCCAACAAGGCGGCT
GACGCCAAATACCGTTGA

Upstream 100 bases:

>100_bases
CCCCGGGGGGCGCTGCGCCTGCGGCCCGGCAAAGCCGGTTCCGCGGCCCCTGCTTGCATCAACGTGTCGCCAGCGAGCTC
CACTCCCGCAGGAAACTGAT

Downstream 100 bases:

>100_bases
ATTACCTCGCCACGCAAGTCGGCTCAAGAAAGAATCCACAATAACATGGACGCTAAAACAGGTCTCTTTTATGTTTTTGC
CGCGGTGCTGCTGTTCGCGG

Product: NADH dehydrogenase subunit I

Products: NA

Alternate protein names: NADH dehydrogenase I subunit I; NDH-1 subunit I [H]

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MSTVASVKDFVSSFMLTELFKGMALTGKYMFSRKITVQFPEEKTPLSPRFRGLHALRRYDNGEERCIACKLCEAVCPALA
ITIESEVRDDGSRRTSRYDIDLTKCIFCGFCEEACPVDAIVETHIFEYHGEKRGDLYFTKEMLLAVGDRYEAEIAANKAA
DAKYR

Sequences:

>Translated_165_residues
MSTVASVKDFVSSFMLTELFKGMALTGKYMFSRKITVQFPEEKTPLSPRFRGLHALRRYDNGEERCIACKLCEAVCPALA
ITIESEVRDDGSRRTSRYDIDLTKCIFCGFCEEACPVDAIVETHIFEYHGEKRGDLYFTKEMLLAVGDRYEAEIAANKAA
DAKYR
>Mature_164_residues
STVASVKDFVSSFMLTELFKGMALTGKYMFSRKITVQFPEEKTPLSPRFRGLHALRRYDNGEERCIACKLCEAVCPALAI
TIESEVRDDGSRRTSRYDIDLTKCIFCGFCEEACPVDAIVETHIFEYHGEKRGDLYFTKEMLLAVGDRYEAEIAANKAAD
AKYR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI4505371, Length=163, Percent_Identity=62.5766871165644, Blast_Score=212, Evalue=1e-55,
Organism=Escherichia coli, GI1788617, Length=127, Percent_Identity=41.7322834645669, Blast_Score=106, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17555194, Length=155, Percent_Identity=60, Blast_Score=197, Evalue=1e-51,
Organism=Drosophila melanogaster, GI17864306, Length=162, Percent_Identity=61.1111111111111, Blast_Score=203, Evalue=4e-53,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR010226 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18738; Mature: 18606

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00028 ZINC_FINGER_C2H2_1 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
4.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVASVKDFVSSFMLTELFKGMALTGKYMFSRKITVQFPEEKTPLSPRFRGLHALRRYD
CCHHHHHHHHHHHHHHHHHHHCHHHHCHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHCC
NGEERCIACKLCEAVCPALAITIESEVRDDGSRRTSRYDIDLTKCIFCGFCEEACPVDAI
CCCHHHHHHHHHHHHHHHHEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHH
VETHIFEYHGEKRGDLYFTKEMLLAVGDRYEAEIAANKAADAKYR
HHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure 
STVASVKDFVSSFMLTELFKGMALTGKYMFSRKITVQFPEEKTPLSPRFRGLHALRRYD
CHHHHHHHHHHHHHHHHHHHCHHHHCHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHCC
NGEERCIACKLCEAVCPALAITIESEVRDDGSRRTSRYDIDLTKCIFCGFCEEACPVDAI
CCCHHHHHHHHHHHHHHHHEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHH
VETHIFEYHGEKRGDLYFTKEMLLAVGDRYEAEIAANKAADAKYR
HHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA