| Definition | Polaromonas sp. JS666 chromosome, complete genome. |
|---|---|
| Accession | NC_007948 |
| Length | 5,200,264 |
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The map label for this gene is parC [H]
Identifier: 91789023
GI number: 91789023
Start: 3346214
End: 3348568
Strand: Reverse
Name: parC [H]
Synonym: Bpro_3163
Alternate gene names: 91789023
Gene position: 3348568-3346214 (Counterclockwise)
Preceding gene: 91789024
Following gene: 91789018
Centisome position: 64.39
GC content: 65.44
Gene sequence:
>2355_bases ATGGATCTCTTTACACCGGACGCAGTAGCCCCGATCCCCGAACCTGCTGACCAGGACTCGCTCGCCGCCTATGCGCAGCG CGCCTACCTGGAATACGCGCTGAGCGTTGTCAAGGGCAGGGCGCTGCCCGACGTGTGCGATGGCCAGAAGCCCGTGCAGC GGCGCATTTTGTACAGCATGGCGCGCATGGGCCTGGGCTTTGGCGGCGCCAATGGTGCAAGCGGGGCCAAGCCGGTCAAG AGCGCGCGCGTCGTCGGCGACGTGCTCGGCAAATACCATCCGCACGGCGACCAGGCGGCTTACGACGCGATGGTGCGCAT GGCGCAGGACTTCAGCCAGCGTTACCCGCTGGTCGACGGCCAGGGCAATTTCGGCTCGCGCGACGGCGACGGGGCGGCGG CCATGCGTTATACCGAGGCTCGGCTGGCGCGCATCACAACCTTGTTGCTCGACGAACTCGACGAAGGCACGGTCGACTTT GCGCCGAATTACGATGGCTCGTTCGAAGAGCCGCGCCAGTTGCCGGCGCGCCTGCCGTTCACGCTGCTTAACGGCGCCAG CGGCATTGCCGTGGGCCTGGCCACCGAGATTCCCAGCCACAACCTGCGCGAAGTGGCCGACGCCTGCGTCGCCCTGATCA AGACGCCCAGGCTCAGCGATGAAGAGCTGTACACGCTGATCGCCGGTCCCGACTACCCGGGCGGCGGACAGATCATTTCC AGCACGGCGGAAATTGCGGCGGCCTACAGCACCGGCCGGGGTTCTCTCAAGGTACGCGCGCGCTGGAAGATTGAGGACCT GGCCCGCGGCCAGTGGCAGCTGGTGGTGCAGGAGTTGCCTCCCGGCGTCAGCACCCAGCGCGTGCTGGAAGAGATTGAAG AGCTGACCAATCCCAAGATCAAGGCCGGCAAAAAGGCCTTGAGCCAGGAGCAGGTGCAGCTCAAGCAGACCGTGCTGTCG GTGCTCGATGTGGTGCGCGATGAGTCCAGCAAGGACGCCGCGGTGCGCCTGGTGTTCGAGCCCAAGACCAGCAGAATCGG GCAGTCCGAGCTCATCAATACCTTGCTGGCGCACACCAGCCTGGAGAGCTCTGCCTCCATCAACCTGACCATGGTCGGGC TCGACGGCAAGCCGACGCAAAAGACGCTGCGGCAGATGCTGGGCGAGTGGATCGAGTTCCGCCAGGCCACGGTGCAACGG CGCTCGCAGCACCGGCTCGATAAGGTCCTCGACCGCATTCACATCCTCGAGGGACGGCAGCTGGTGCTGCTCAACATCGA TGAGGTAATTGCCATCATCCGCCAGTCGGACGAACCCAAGGCCGCGCTGATCGCCCGCTTCTCGTTAAGCGAGCGGCAGG CCGAAGACATCCTCGAAATCCGCCTGCGCCAGCTGGCGCGGCTTGAGGCCATCAAGATCGAGCAAGAGCTCAAAACCCTG CGCGAAGAGCAGGGCAAGCTCGAGGAAATCCTGGGCAGCCCGGCGGCGCTTCGCCGGCTGCTGGTCAAGGAAATTGAAGC GGACGCCAAACAGTTTGCCGACCCGCGCCGCACGCTGATCCAGGCCGAGAAAAAGGCTGTGCTCGAAGTCAAGGTGCTGG ACGAGCCGGTCACGGTGGTGGTGAGCGCCAAGGGCTGGGTGCGCGCCCGCTCGGGCCACGGCCACGACGCTGCAAGCTTT GCCTTCAAGGCGGGCGACGGCCTGTACGCCACGTTCGAATGCCGTACCGTCGATACCCTGCTGGCCTTTGGCTCACGCGG CCGTATTTACTCTGTCCCGGTGGCGTCCCTGCCGGGCGCGCGCGGTGACGGGCAGCCGCTCACGACGCTGATCGACCTGG AGTCCGGCACGCAGTTGGTGCATTACTTTGCGGGTCCTGCCAACGCAACGCTGCTCCTCAGCGCCAGCGGCGGCTACGGT TTTCTTGCCACGGTTGAAAACATGACCTCACGCCTGAAGGCCGGCAAGGCCTTCATCAGTTGCGCGGAGGGCGAAACCGT GTGCCGGCCATCGCACGTCTCGGGCGGAACGGGCGCGACCCCGCTCAACCCGGCTACGCATGTGGCCTGCGCCTCGACGG GTGGCCGCATCCTTACCTTCGAGATTGCCGAACTCAAACTTCAGGCGGCCGGTGGACGCGGCTTGATGCTGCTGGACCTG GATGCCAAGGACACGCTGGCCGGCGCAGCGGCCTACACCCGCAGCGTGAAGATCGAAGGCATCGGGCGCGGTGGCAAGGC GCGGGAGGAGACTCTGGAGATCCGTAGCCTGAACAATGCCCGTGCGGCGCGTGCCCGCAAAGGCAAGGCGGCCGACCTGG GCTTCAAACCGACGGGTATTGTCCGGGTGGAATAA
Upstream 100 bases:
>100_bases GAAAAACGGCTCCCCCTGCATTTCTTTGTAGCCCTGTGCCGGCCGCACCAGTGTGTACCGGCATGCGTAACTCCACCTTA CCAGCCAAGTCAAATTCAAG
Downstream 100 bases:
>100_bases GTCTTGCTGTGGGGCGCCTGAGTGAGCTCAGGCCACCTCGGCAATCAGCTCGATCTCAACGCAGGCGCCCATCGGGATTT GTGCCACGCCGAAAGCGCTG
Product: DNA topoisomerase IV subunit A
Products: NA
Alternate protein names: Topoisomerase IV subunit A [H]
Number of amino acids: Translated: 784; Mature: 784
Protein sequence:
>784_residues MDLFTPDAVAPIPEPADQDSLAAYAQRAYLEYALSVVKGRALPDVCDGQKPVQRRILYSMARMGLGFGGANGASGAKPVK SARVVGDVLGKYHPHGDQAAYDAMVRMAQDFSQRYPLVDGQGNFGSRDGDGAAAMRYTEARLARITTLLLDELDEGTVDF APNYDGSFEEPRQLPARLPFTLLNGASGIAVGLATEIPSHNLREVADACVALIKTPRLSDEELYTLIAGPDYPGGGQIIS STAEIAAAYSTGRGSLKVRARWKIEDLARGQWQLVVQELPPGVSTQRVLEEIEELTNPKIKAGKKALSQEQVQLKQTVLS VLDVVRDESSKDAAVRLVFEPKTSRIGQSELINTLLAHTSLESSASINLTMVGLDGKPTQKTLRQMLGEWIEFRQATVQR RSQHRLDKVLDRIHILEGRQLVLLNIDEVIAIIRQSDEPKAALIARFSLSERQAEDILEIRLRQLARLEAIKIEQELKTL REEQGKLEEILGSPAALRRLLVKEIEADAKQFADPRRTLIQAEKKAVLEVKVLDEPVTVVVSAKGWVRARSGHGHDAASF AFKAGDGLYATFECRTVDTLLAFGSRGRIYSVPVASLPGARGDGQPLTTLIDLESGTQLVHYFAGPANATLLLSASGGYG FLATVENMTSRLKAGKAFISCAEGETVCRPSHVSGGTGATPLNPATHVACASTGGRILTFEIAELKLQAAGGRGLMLLDL DAKDTLAGAAAYTRSVKIEGIGRGGKAREETLEIRSLNNARAARARKGKAADLGFKPTGIVRVE
Sequences:
>Translated_784_residues MDLFTPDAVAPIPEPADQDSLAAYAQRAYLEYALSVVKGRALPDVCDGQKPVQRRILYSMARMGLGFGGANGASGAKPVK SARVVGDVLGKYHPHGDQAAYDAMVRMAQDFSQRYPLVDGQGNFGSRDGDGAAAMRYTEARLARITTLLLDELDEGTVDF APNYDGSFEEPRQLPARLPFTLLNGASGIAVGLATEIPSHNLREVADACVALIKTPRLSDEELYTLIAGPDYPGGGQIIS STAEIAAAYSTGRGSLKVRARWKIEDLARGQWQLVVQELPPGVSTQRVLEEIEELTNPKIKAGKKALSQEQVQLKQTVLS VLDVVRDESSKDAAVRLVFEPKTSRIGQSELINTLLAHTSLESSASINLTMVGLDGKPTQKTLRQMLGEWIEFRQATVQR RSQHRLDKVLDRIHILEGRQLVLLNIDEVIAIIRQSDEPKAALIARFSLSERQAEDILEIRLRQLARLEAIKIEQELKTL REEQGKLEEILGSPAALRRLLVKEIEADAKQFADPRRTLIQAEKKAVLEVKVLDEPVTVVVSAKGWVRARSGHGHDAASF AFKAGDGLYATFECRTVDTLLAFGSRGRIYSVPVASLPGARGDGQPLTTLIDLESGTQLVHYFAGPANATLLLSASGGYG FLATVENMTSRLKAGKAFISCAEGETVCRPSHVSGGTGATPLNPATHVACASTGGRILTFEIAELKLQAAGGRGLMLLDL DAKDTLAGAAAYTRSVKIEGIGRGGKAREETLEIRSLNNARAARARKGKAADLGFKPTGIVRVE >Mature_784_residues MDLFTPDAVAPIPEPADQDSLAAYAQRAYLEYALSVVKGRALPDVCDGQKPVQRRILYSMARMGLGFGGANGASGAKPVK SARVVGDVLGKYHPHGDQAAYDAMVRMAQDFSQRYPLVDGQGNFGSRDGDGAAAMRYTEARLARITTLLLDELDEGTVDF APNYDGSFEEPRQLPARLPFTLLNGASGIAVGLATEIPSHNLREVADACVALIKTPRLSDEELYTLIAGPDYPGGGQIIS STAEIAAAYSTGRGSLKVRARWKIEDLARGQWQLVVQELPPGVSTQRVLEEIEELTNPKIKAGKKALSQEQVQLKQTVLS VLDVVRDESSKDAAVRLVFEPKTSRIGQSELINTLLAHTSLESSASINLTMVGLDGKPTQKTLRQMLGEWIEFRQATVQR RSQHRLDKVLDRIHILEGRQLVLLNIDEVIAIIRQSDEPKAALIARFSLSERQAEDILEIRLRQLARLEAIKIEQELKTL REEQGKLEEILGSPAALRRLLVKEIEADAKQFADPRRTLIQAEKKAVLEVKVLDEPVTVVVSAKGWVRARSGHGHDAASF AFKAGDGLYATFECRTVDTLLAFGSRGRIYSVPVASLPGARGDGQPLTTLIDLESGTQLVHYFAGPANATLLLSASGGYG FLATVENMTSRLKAGKAFISCAEGETVCRPSHVSGGTGATPLNPATHVACASTGGRILTFEIAELKLQAAGGRGLMLLDL DAKDTLAGAAAYTRSVKIEGIGRGGKAREETLEIRSLNNARAARARKGKAADLGFKPTGIVRVE
Specific function: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule [H]
COG id: COG0188
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
Gene ontology:
Cell location: Cell membrane; Peripheral membrane protein [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the topoisomerase gyrA/parC subunit family [H]
Homologues:
Organism=Homo sapiens, GI19913408, Length=174, Percent_Identity=31.6091954022989, Blast_Score=82, Evalue=1e-15, Organism=Homo sapiens, GI19913406, Length=180, Percent_Identity=29.4444444444444, Blast_Score=80, Evalue=8e-15, Organism=Escherichia coli, GI1789396, Length=717, Percent_Identity=44.6304044630404, Blast_Score=596, Evalue=1e-171, Organism=Escherichia coli, GI1788562, Length=761, Percent_Identity=37.5821287779238, Blast_Score=409, Evalue=1e-115, Organism=Caenorhabditis elegans, GI212645845, Length=386, Percent_Identity=24.3523316062176, Blast_Score=88, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17535065, Length=180, Percent_Identity=31.1111111111111, Blast_Score=78, Evalue=2e-14, Organism=Caenorhabditis elegans, GI212645657, Length=179, Percent_Identity=31.8435754189944, Blast_Score=77, Evalue=4e-14, Organism=Saccharomyces cerevisiae, GI6324241, Length=376, Percent_Identity=27.3936170212766, Blast_Score=77, Evalue=7e-15, Organism=Drosophila melanogaster, GI17136538, Length=286, Percent_Identity=26.2237762237762, Blast_Score=84, Evalue=5e-16,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020899 - InterPro: IPR002205 - InterPro: IPR013758 - InterPro: IPR013757 - InterPro: IPR013760 - InterPro: IPR005742 [H]
Pfam domain/function: PF00521 DNA_topoisoIV [H]
EC number: 5.99.1.-
Molecular weight: Translated: 84605; Mature: 84605
Theoretical pI: Translated: 7.88; Mature: 7.88
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 2.0 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDLFTPDAVAPIPEPADQDSLAAYAQRAYLEYALSVVKGRALPDVCDGQKPVQRRILYSM CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH ARMGLGFGGANGASGAKPVKSARVVGDVLGKYHPHGDQAAYDAMVRMAQDFSQRYPLVDG HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEECC QGNFGSRDGDGAAAMRYTEARLARITTLLLDELDEGTVDFAPNYDGSFEEPRQLPARLPF CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHCCCCCCC TLLNGASGIAVGLATEIPSHNLREVADACVALIKTPRLSDEELYTLIAGPDYPGGGQIIS CEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHH STAEIAAAYSTGRGSLKVRARWKIEDLARGQWQLVVQELPPGVSTQRVLEEIEELTNPKI HHHHHHHHHCCCCCCEEEEEEECHHHHCCCHHEEHHHHCCCCCCHHHHHHHHHHHCCCCH KAGKKALSQEQVQLKQTVLSVLDVVRDESSKDAAVRLVFEPKTSRIGQSELINTLLAHTS HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCC LESSASINLTMVGLDGKPTQKTLRQMLGEWIEFRQATVQRRSQHRLDKVLDRIHILEGRQ CCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE LVLLNIDEVIAIIRQSDEPKAALIARFSLSERQAEDILEIRLRQLARLEAIKIEQELKTL EEEEEHHHHHHHHHCCCCCCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH REEQGKLEEILGSPAALRRLLVKEIEADAKQFADPRRTLIQAEKKAVLEVKVLDEPVTVV HHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEEEECCCEEEE VSAKGWVRARSGHGHDAASFAFKAGDGLYATFECRTVDTLLAFGSRGRIYSVPVASLPGA EECCCCEEECCCCCCCHHHEEEECCCCEEEEEECHHHHHHHHCCCCCCEEECCHHHCCCC RGDGQPLTTLIDLESGTQLVHYFAGPANATLLLSASGGYGFLATVENMTSRLKAGKAFIS CCCCCCCEEEEEECCCCEEEEEECCCCCEEEEEECCCCCEEEHHHHHHHHHHHHCHHEEE CAEGETVCRPSHVSGGTGATPLNPATHVACASTGGRILTFEIAELKLQAAGGRGLMLLDL ECCCCCEECCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEEEEEEEEECCCCEEEEEEC DAKDTLAGAAAYTRSVKIEGIGRGGKAREETLEIRSLNNARAARARKGKAADLGFKPTGI CCCHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCE VRVE EEEC >Mature Secondary Structure MDLFTPDAVAPIPEPADQDSLAAYAQRAYLEYALSVVKGRALPDVCDGQKPVQRRILYSM CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH ARMGLGFGGANGASGAKPVKSARVVGDVLGKYHPHGDQAAYDAMVRMAQDFSQRYPLVDG HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEECC QGNFGSRDGDGAAAMRYTEARLARITTLLLDELDEGTVDFAPNYDGSFEEPRQLPARLPF CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHCCCCCCC TLLNGASGIAVGLATEIPSHNLREVADACVALIKTPRLSDEELYTLIAGPDYPGGGQIIS CEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHH STAEIAAAYSTGRGSLKVRARWKIEDLARGQWQLVVQELPPGVSTQRVLEEIEELTNPKI HHHHHHHHHCCCCCCEEEEEEECHHHHCCCHHEEHHHHCCCCCCHHHHHHHHHHHCCCCH KAGKKALSQEQVQLKQTVLSVLDVVRDESSKDAAVRLVFEPKTSRIGQSELINTLLAHTS HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCC LESSASINLTMVGLDGKPTQKTLRQMLGEWIEFRQATVQRRSQHRLDKVLDRIHILEGRQ CCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE LVLLNIDEVIAIIRQSDEPKAALIARFSLSERQAEDILEIRLRQLARLEAIKIEQELKTL EEEEEHHHHHHHHHCCCCCCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH REEQGKLEEILGSPAALRRLLVKEIEADAKQFADPRRTLIQAEKKAVLEVKVLDEPVTVV HHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEEEECCCEEEE VSAKGWVRARSGHGHDAASFAFKAGDGLYATFECRTVDTLLAFGSRGRIYSVPVASLPGA EECCCCEEECCCCCCCHHHEEEECCCCEEEEEECHHHHHHHHCCCCCCEEECCHHHCCCC RGDGQPLTTLIDLESGTQLVHYFAGPANATLLLSASGGYGFLATVENMTSRLKAGKAFIS CCCCCCCEEEEEECCCCEEEEEECCCCCEEEEEECCCCCEEEHHHHHHHHHHHHCHHEEE CAEGETVCRPSHVSGGTGATPLNPATHVACASTGGRILTFEIAELKLQAAGGRGLMLLDL ECCCCCEECCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEEEEEEEEECCCCEEEEEEC DAKDTLAGAAAYTRSVKIEGIGRGGKAREETLEIRSLNNARAARARKGKAADLGFKPTGI CCCHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCE VRVE EEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7830580 [H]