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The map label for this gene is comA [H]

Identifier: 91789018

GI number: 91789018

Start: 3334978

End: 3337560

Strand: Reverse

Name: comA [H]

Synonym: Bpro_3158

Alternate gene names: 91789018

Gene position: 3337560-3334978 (Counterclockwise)

Preceding gene: 91789023

Following gene: 91789017

Centisome position: 64.18

GC content: 68.22

Gene sequence:

>2583_bases
GTGGGCGACCGTGTATCAGCCAGACCATGGGCGGCCTCCATGGGGCCTGGCCTTGTCTTTGGCGGCTTCATCACCGGGGT
AGCCTTGCAGCTGCAGCAGCCCGGTTTGTGGCCGGGCAGCCTGTATCCCGCATTGGCGGTGCTCGCGGCACTGGCGGGGG
TGGTAATGGGCGCTTGGTGGCTCATGGCTGGCCGCAGCTCGCCTCTGACCCTGAACGTCAGGGGTTTTCGCGGTGTGGGT
GTGGTGGCCCTGGCGCTCGCGGCCCTGCTGGGCTTTGGCCTGACGGGGTGGCGGGCCACGGTCTTTCAGTCGGCGGCACT
CGACCCCGCGCTGGAGGGTCGCGATATTGCCGTGACGGGTGTGGTGCTGGCCATGCCGCAACCCGCCGAAGACGGCCTGC
GCTTTCGCCTGGGTATTGAATCGGCCCGCCTGAATGGGCAAACAGTCACCTTGCCGCGGCATATCCTGCTTGGCTGGTAC
AGCGGCTTCGGCATGCGGGACGGCAGGGCATCGCCGGCCGAAAGCGCCGATCCGTCTGACCTTGCGCTGGAGCTGCAGCG
CCAGCCGCAGGACTTGCGCGCGGGCGAGCGCTGGCAGATGACGGTGCGGCTGAAGGTCCCGCACGGCAACAGCAACCCGC
ACGGATTCGACTACGAACTCTGGCTGTGGGAGCAGGGCATTCAGGCCACCGGCTATGTGCGCGCCGGGCTGAACGATGCG
CCGCCCCGACGGCTGTCCGGCGGCTGGGATCATCCGGTAGAGAGCGCCCGGCAGTCGGTGCGTGAAGCGATTTTCCAGCG
CGTTGGCAACCGCCAGCTGGCCGGTGTAGTGGCCGCCCTGGTGGTGGGCGACCAGAACGCCATTGATCGCGCTGACTGGG
ATGTCTTTCGCGCCACCGGTGTCGCTCACCTGATGAGTATTTCGGGCCTGCACATCACCATGTTCGCCTGGCTCGCCTCC
CTGCTGTTGAGCGGCCTGTGGCGGCGCTCTGCCGGGTTGACGCCCCGGCTTTGCCTGGCGCTGCCGGCCGTCAGCGCCGG
AGCCTGGGGCGGCCTGTTGCTCGCGGTCCTGTACGCGCTGTTTTCAGGCTGGGGCGTGCCGGCGCAGAGAACCATCTGGA
TGCTGGCGACGGTGGTGTTGCTGCGGCACAGCGGCAAGCAGTGGCCCTGGCTGCAAACCTGGCTGCTGGCCATGGCGGTG
GTGGTCACGCTGGACCCCTGGGCGCTGATGCAGGCGGGTTTCTGGCTGTCGTTTGTTGCGGTGGGCGTGCTGTTTGCTGC
AAATCCAGGAGCGTCTGGTGCCCGTGATTCGGCGGGTGATGGCCCGCTTCTCTCAGGAAGTCCGGTGAAGCAAGGGTGGG
TGCCGCGGCTGTTGGCAAAACCGGCTGCTGCCTTGCTGCGCGCCGCCCGGGAGCAATGGGTGGTCACGCTGGCGCTCACG
CCCCTGTCGCTGCTGCTGTTCAACCAGGTGTCGCTGGTCGGCCTGCTGGCCAACGCGGTGGCCATTCCCTGGGTGACGCT
GGTTGTGACGCCGCTGGCCATGCTGGGCGTGCTGTGGGCGCCGGTGTGGGACGCGGCGGCGTGGGCCGTGGGCCTGCTGG
CGGTCTTTTTGCAGTGGCTGGCCGCCTGGCCGCTGGCCTCTGTCAGCGTGGCCGCGGCGCCGCCGTGGTGCGCTGCCTTT
GGTGTGCTGGGGGGTGTTTTGCTGGCGCTGCGCCTGCCCTGGCACTGGCGCGCTCTGGGCGTGCCGCTACTGCTCCCCGT
ACTGCTGTGGCAACCGGTGCGGGTCGCGCCGGGGCAGTTTGAGTTGCTGGCAGCGGACATCGGGCAGGGCAATGCCGTAC
TGGTGCGCACGGCCACCCATTCGCTGCTGTATGACACCGGCCCGCGCTTTTCGCGCGAGAGCGATGCCGGGCACCGCGTG
CTGGTGCCGCTGCTGCGCGCCCTTGGTGAGCGACTGGACATGCTGATGCTGAGCCACCGGGATATCGACCATATTGGCGG
CGCGCGGGCCGTGCTGGCCATGCAGCCGCAAGCCAGCCTGCTCAGCTCGATTGAGGACAGCCACGAGTTGCAGGCTGTGC
GCAAATCGGCCCGCTGCACGGCGGGCCTGCGCTGGGTCTGGGATGCGGTGACTTTTGAAGTGCTGCACCCGGTGGCCGCC
GACTACGAGGCGGCGAACAAATCCAATGCCATGAGCTGCGTGCTGCGTATCTCCAACGGCGCGCAGACCGCCTTGCTGGC
GGGCGACATCGAGTCCGCCCAGGAGCTCCGGCTGGCCACCAGCGGTGACCCGCCTGGCCTGAAGGCCGACTTTTTGCTGG
TGCCGCACCACGGCAGCAAGACCTCGTCGAGTGCTGTGTTCCTCGATGCCGTCCAGCCCCGGCTGGCGCTGGTGCAGGCA
GGCTACCGCAACCGGTTTGGCCATCCGGTGGACTTGGTGGTGGCGCGCTACAACGAACGCGGCATCAGGCTGCTCAGGTC
GCCGCAGTGTGGGGCAGCCGTCTGGCAGAGCCTGAAACCGGCGGACATCACGTGCCAGCGGCAGGCAGGCCAGCACTACT
GGCATCATGTGCCTGAGCCATAA

Upstream 100 bases:

>100_bases
AGGCTTTGTCGGCTTTTTGCGTCGTCCGGCCGTTGAACACGCAGCCATTGCATCAAACAACATTGAACAAAGCAATCAAT
AACAAGTGGGGGAGGAGGCT

Downstream 100 bases:

>100_bases
GGAAAAGGAGAAAAAAAAGGATTCCACCGGAAGTGAAAAAGAAAACCGCGACGTGATACCCGATTCGCCAATCTGGCGCA
TAACTTGCTAAGCTAGTCAT

Product: DNA internalization-like protein competence protein ComEC/Rec2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 860; Mature: 859

Protein sequence:

>860_residues
MGDRVSARPWAASMGPGLVFGGFITGVALQLQQPGLWPGSLYPALAVLAALAGVVMGAWWLMAGRSSPLTLNVRGFRGVG
VVALALAALLGFGLTGWRATVFQSAALDPALEGRDIAVTGVVLAMPQPAEDGLRFRLGIESARLNGQTVTLPRHILLGWY
SGFGMRDGRASPAESADPSDLALELQRQPQDLRAGERWQMTVRLKVPHGNSNPHGFDYELWLWEQGIQATGYVRAGLNDA
PPRRLSGGWDHPVESARQSVREAIFQRVGNRQLAGVVAALVVGDQNAIDRADWDVFRATGVAHLMSISGLHITMFAWLAS
LLLSGLWRRSAGLTPRLCLALPAVSAGAWGGLLLAVLYALFSGWGVPAQRTIWMLATVVLLRHSGKQWPWLQTWLLAMAV
VVTLDPWALMQAGFWLSFVAVGVLFAANPGASGARDSAGDGPLLSGSPVKQGWVPRLLAKPAAALLRAAREQWVVTLALT
PLSLLLFNQVSLVGLLANAVAIPWVTLVVTPLAMLGVLWAPVWDAAAWAVGLLAVFLQWLAAWPLASVSVAAAPPWCAAF
GVLGGVLLALRLPWHWRALGVPLLLPVLLWQPVRVAPGQFELLAADIGQGNAVLVRTATHSLLYDTGPRFSRESDAGHRV
LVPLLRALGERLDMLMLSHRDIDHIGGARAVLAMQPQASLLSSIEDSHELQAVRKSARCTAGLRWVWDAVTFEVLHPVAA
DYEAANKSNAMSCVLRISNGAQTALLAGDIESAQELRLATSGDPPGLKADFLLVPHHGSKTSSSAVFLDAVQPRLALVQA
GYRNRFGHPVDLVVARYNERGIRLLRSPQCGAAVWQSLKPADITCQRQAGQHYWHHVPEP

Sequences:

>Translated_860_residues
MGDRVSARPWAASMGPGLVFGGFITGVALQLQQPGLWPGSLYPALAVLAALAGVVMGAWWLMAGRSSPLTLNVRGFRGVG
VVALALAALLGFGLTGWRATVFQSAALDPALEGRDIAVTGVVLAMPQPAEDGLRFRLGIESARLNGQTVTLPRHILLGWY
SGFGMRDGRASPAESADPSDLALELQRQPQDLRAGERWQMTVRLKVPHGNSNPHGFDYELWLWEQGIQATGYVRAGLNDA
PPRRLSGGWDHPVESARQSVREAIFQRVGNRQLAGVVAALVVGDQNAIDRADWDVFRATGVAHLMSISGLHITMFAWLAS
LLLSGLWRRSAGLTPRLCLALPAVSAGAWGGLLLAVLYALFSGWGVPAQRTIWMLATVVLLRHSGKQWPWLQTWLLAMAV
VVTLDPWALMQAGFWLSFVAVGVLFAANPGASGARDSAGDGPLLSGSPVKQGWVPRLLAKPAAALLRAAREQWVVTLALT
PLSLLLFNQVSLVGLLANAVAIPWVTLVVTPLAMLGVLWAPVWDAAAWAVGLLAVFLQWLAAWPLASVSVAAAPPWCAAF
GVLGGVLLALRLPWHWRALGVPLLLPVLLWQPVRVAPGQFELLAADIGQGNAVLVRTATHSLLYDTGPRFSRESDAGHRV
LVPLLRALGERLDMLMLSHRDIDHIGGARAVLAMQPQASLLSSIEDSHELQAVRKSARCTAGLRWVWDAVTFEVLHPVAA
DYEAANKSNAMSCVLRISNGAQTALLAGDIESAQELRLATSGDPPGLKADFLLVPHHGSKTSSSAVFLDAVQPRLALVQA
GYRNRFGHPVDLVVARYNERGIRLLRSPQCGAAVWQSLKPADITCQRQAGQHYWHHVPEP
>Mature_859_residues
GDRVSARPWAASMGPGLVFGGFITGVALQLQQPGLWPGSLYPALAVLAALAGVVMGAWWLMAGRSSPLTLNVRGFRGVGV
VALALAALLGFGLTGWRATVFQSAALDPALEGRDIAVTGVVLAMPQPAEDGLRFRLGIESARLNGQTVTLPRHILLGWYS
GFGMRDGRASPAESADPSDLALELQRQPQDLRAGERWQMTVRLKVPHGNSNPHGFDYELWLWEQGIQATGYVRAGLNDAP
PRRLSGGWDHPVESARQSVREAIFQRVGNRQLAGVVAALVVGDQNAIDRADWDVFRATGVAHLMSISGLHITMFAWLASL
LLSGLWRRSAGLTPRLCLALPAVSAGAWGGLLLAVLYALFSGWGVPAQRTIWMLATVVLLRHSGKQWPWLQTWLLAMAVV
VTLDPWALMQAGFWLSFVAVGVLFAANPGASGARDSAGDGPLLSGSPVKQGWVPRLLAKPAAALLRAAREQWVVTLALTP
LSLLLFNQVSLVGLLANAVAIPWVTLVVTPLAMLGVLWAPVWDAAAWAVGLLAVFLQWLAAWPLASVSVAAAPPWCAAFG
VLGGVLLALRLPWHWRALGVPLLLPVLLWQPVRVAPGQFELLAADIGQGNAVLVRTATHSLLYDTGPRFSRESDAGHRVL
VPLLRALGERLDMLMLSHRDIDHIGGARAVLAMQPQASLLSSIEDSHELQAVRKSARCTAGLRWVWDAVTFEVLHPVAAD
YEAANKSNAMSCVLRISNGAQTALLAGDIESAQELRLATSGDPPGLKADFLLVPHHGSKTSSSAVFLDAVQPRLALVQAG
YRNRFGHPVDLVVARYNERGIRLLRSPQCGAAVWQSLKPADITCQRQAGQHYWHHVPEP

Specific function: Essential for natural transformation. Could be a transporter involved in DNA uptake [H]

COG id: COG0658

COG function: function code R; Predicted membrane metal-binding protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis ComEC, H.influenzae REC2, and E.coli YcaI [H]

Homologues:

Organism=Escherichia coli, GI87081801, Length=671, Percent_Identity=28.3159463487332, Blast_Score=201, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR004477
- InterPro:   IPR004797 [H]

Pfam domain/function: PF03772 Competence; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 92372; Mature: 92241

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDRVSARPWAASMGPGLVFGGFITGVALQLQQPGLWPGSLYPALAVLAALAGVVMGAWW
CCCCCCCCCCCCCCCCCHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LMAGRSSPLTLNVRGFRGVGVVALALAALLGFGLTGWRATVFQSAALDPALEGRDIAVTG
HHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEEEEE
VVLAMPQPAEDGLRFRLGIESARLNGQTVTLPRHILLGWYSGFGMRDGRASPAESADPSD
EEEECCCCCCCCCEEEEECHHHHCCCCEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCHH
LALELQRQPQDLRAGERWQMTVRLKVPHGNSNPHGFDYELWLWEQGIQATGYVRAGLNDA
HHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCEEECCCCCC
PPRRLSGGWDHPVESARQSVREAIFQRVGNRQLAGVVAALVVGDQNAIDRADWDVFRATG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
VAHLMSISGLHITMFAWLASLLLSGLWRRSAGLTPRLCLALPAVSAGAWGGLLLAVLYAL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHH
FSGWGVPAQRTIWMLATVVLLRHSGKQWPWLQTWLLAMAVVVTLDPWALMQAGFWLSFVA
HCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VGVLFAANPGASGARDSAGDGPLLSGSPVKQGWVPRLLAKPAAALLRAAREQWVVTLALT
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEHH
PLSLLLFNQVSLVGLLANAVAIPWVTLVVTPLAMLGVLWAPVWDAAAWAVGLLAVFLQWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAWPLASVSVAAAPPWCAAFGVLGGVLLALRLPWHWRALGVPLLLPVLLWQPVRVAPGQF
HHCCHHHCEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHCCCCCCCCCCE
ELLAADIGQGNAVLVRTATHSLLYDTGPRFSRESDAGHRVLVPLLRALGERLDMLMLSHR
EEEEEECCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
DIDHIGGARAVLAMQPQASLLSSIEDSHELQAVRKSARCTAGLRWVWDAVTFEVLHPVAA
CHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
DYEAANKSNAMSCVLRISNGAQTALLAGDIESAQELRLATSGDPPGLKADFLLVPHHGSK
CHHHCCCCCCEEEEEEECCCCCEEEEECCHHHHHHHEEECCCCCCCCCEEEEEECCCCCC
TSSSAVFLDAVQPRLALVQAGYRNRFGHPVDLVVARYNERGIRLLRSPQCGAAVWQSLKP
CCCCEEEEEHHCHHHHHHHCCHHHCCCCCCEEEEEECCCCCHHEECCCCCCHHHHHCCCC
ADITCQRQAGQHYWHHVPEP
CCCEEHHHCCCHHCCCCCCC
>Mature Secondary Structure 
GDRVSARPWAASMGPGLVFGGFITGVALQLQQPGLWPGSLYPALAVLAALAGVVMGAWW
CCCCCCCCCCCCCCCCHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LMAGRSSPLTLNVRGFRGVGVVALALAALLGFGLTGWRATVFQSAALDPALEGRDIAVTG
HHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEEEEE
VVLAMPQPAEDGLRFRLGIESARLNGQTVTLPRHILLGWYSGFGMRDGRASPAESADPSD
EEEECCCCCCCCCEEEEECHHHHCCCCEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCHH
LALELQRQPQDLRAGERWQMTVRLKVPHGNSNPHGFDYELWLWEQGIQATGYVRAGLNDA
HHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCEEECCCCCC
PPRRLSGGWDHPVESARQSVREAIFQRVGNRQLAGVVAALVVGDQNAIDRADWDVFRATG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
VAHLMSISGLHITMFAWLASLLLSGLWRRSAGLTPRLCLALPAVSAGAWGGLLLAVLYAL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHH
FSGWGVPAQRTIWMLATVVLLRHSGKQWPWLQTWLLAMAVVVTLDPWALMQAGFWLSFVA
HCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VGVLFAANPGASGARDSAGDGPLLSGSPVKQGWVPRLLAKPAAALLRAAREQWVVTLALT
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEHH
PLSLLLFNQVSLVGLLANAVAIPWVTLVVTPLAMLGVLWAPVWDAAAWAVGLLAVFLQWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAWPLASVSVAAAPPWCAAFGVLGGVLLALRLPWHWRALGVPLLLPVLLWQPVRVAPGQF
HHCCHHHCEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHCCCCCCCCCCE
ELLAADIGQGNAVLVRTATHSLLYDTGPRFSRESDAGHRVLVPLLRALGERLDMLMLSHR
EEEEEECCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
DIDHIGGARAVLAMQPQASLLSSIEDSHELQAVRKSARCTAGLRWVWDAVTFEVLHPVAA
CHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
DYEAANKSNAMSCVLRISNGAQTALLAGDIESAQELRLATSGDPPGLKADFLLVPHHGSK
CHHHCCCCCCEEEEEEECCCCCEEEEECCHHHHHHHEEECCCCCCCCCEEEEEECCCCCC
TSSSAVFLDAVQPRLALVQAGYRNRFGHPVDLVVARYNERGIRLLRSPQCGAAVWQSLKP
CCCCEEEEEHHCHHHHHHHCCHHHCCCCCCEEEEEECCCCCHHEECCCCCCHHHHHCCCC
ADITCQRQAGQHYWHHVPEP
CCCEEHHHCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934834; 8830266 [H]