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The map label for this gene is fbp [H]

Identifier: 91788941

GI number: 91788941

Start: 3249956

End: 3250303

Strand: Reverse

Name: fbp [H]

Synonym: Bpro_3081

Alternate gene names: 91788941

Gene position: 3250303-3249956 (Counterclockwise)

Preceding gene: 91788942

Following gene: 91788940

Centisome position: 62.5

GC content: 64.94

Gene sequence:

>348_bases
ATGACAACCACTTCATCAGGACTGCAATACGAAGACACCGTGCTGGGCACGGGTGCCATTGCCAAGGCAGGGCAGCATGT
CAAGGTGCATTACACCGGCTGGCTGTACAACGGCGGTACGCAGGGCGCCAAATTCGACTCCAGCAAGGACCGCGGCCAGC
CCTTCGAGTTCTCGCTCGGTGCGGGCCAGGTCATCCGTGGCTGGGACGAGGGCGTGCAGGGCATGTCGGTCGGGGGCACG
CGCCGCCTGATCATTCCGGCCGAGCTGGGCTATGGCGCACGCGGCGCCGGCGGCGTGATCCCGCCCAATGCCACCTTGCT
GTTTGAAGTCGACCTGCTGGCAACCTGA

Upstream 100 bases:

>100_bases
GTGAACATGCGCTGATTTCCCCTCGCCGGCTTTCTCGCGAACCCCGGAATTTTGGCGCGATTTCCCCTTTTCTTCCTCAT
TTTTCAAAAAGGACATCCAC

Downstream 100 bases:

>100_bases
GCCTCTGCGTTTTCAGCCGCCCCGGAGCAAAGCCGCCACCATGATCATCACCAGCCTGCTTGATACCGACCTGTACAAGT
TCACCATGATGCAGGTGGTG

Product: peptidylprolyl isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 115; Mature: 114

Protein sequence:

>115_residues
MTTTSSGLQYEDTVLGTGAIAKAGQHVKVHYTGWLYNGGTQGAKFDSSKDRGQPFEFSLGAGQVIRGWDEGVQGMSVGGT
RRLIIPAELGYGARGAGGVIPPNATLLFEVDLLAT

Sequences:

>Translated_115_residues
MTTTSSGLQYEDTVLGTGAIAKAGQHVKVHYTGWLYNGGTQGAKFDSSKDRGQPFEFSLGAGQVIRGWDEGVQGMSVGGT
RRLIIPAELGYGARGAGGVIPPNATLLFEVDLLAT
>Mature_114_residues
TTTSSGLQYEDTVLGTGAIAKAGQHVKVHYTGWLYNGGTQGAKFDSSKDRGQPFEFSLGAGQVIRGWDEGVQGMSVGGTR
RLIIPAELGYGARGAGGVIPPNATLLFEVDLLAT

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm And Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI17149836, Length=108, Percent_Identity=51.8518518518518, Blast_Score=104, Evalue=2e-23,
Organism=Homo sapiens, GI4503725, Length=108, Percent_Identity=51.8518518518518, Blast_Score=104, Evalue=2e-23,
Organism=Homo sapiens, GI206725530, Length=93, Percent_Identity=54.8387096774194, Blast_Score=100, Evalue=2e-22,
Organism=Homo sapiens, GI17149844, Length=93, Percent_Identity=54.8387096774194, Blast_Score=100, Evalue=2e-22,
Organism=Homo sapiens, GI17149842, Length=93, Percent_Identity=54.8387096774194, Blast_Score=100, Evalue=2e-22,
Organism=Homo sapiens, GI4758380, Length=108, Percent_Identity=48.1481481481481, Blast_Score=100, Evalue=3e-22,
Organism=Homo sapiens, GI224809331, Length=90, Percent_Identity=52.2222222222222, Blast_Score=89, Evalue=7e-19,
Organism=Homo sapiens, GI4503729, Length=99, Percent_Identity=47.4747474747475, Blast_Score=89, Evalue=7e-19,
Organism=Homo sapiens, GI224809329, Length=90, Percent_Identity=52.2222222222222, Blast_Score=87, Evalue=4e-18,
Organism=Homo sapiens, GI224809327, Length=90, Percent_Identity=52.2222222222222, Blast_Score=87, Evalue=4e-18,
Organism=Homo sapiens, GI4758384, Length=90, Percent_Identity=52.2222222222222, Blast_Score=87, Evalue=4e-18,
Organism=Homo sapiens, GI192448443, Length=110, Percent_Identity=43.6363636363636, Blast_Score=84, Evalue=3e-17,
Organism=Homo sapiens, GI8923659, Length=94, Percent_Identity=46.8085106382979, Blast_Score=84, Evalue=4e-17,
Organism=Homo sapiens, GI150010552, Length=112, Percent_Identity=33.0357142857143, Blast_Score=79, Evalue=7e-16,
Organism=Homo sapiens, GI206725547, Length=102, Percent_Identity=39.2156862745098, Blast_Score=78, Evalue=2e-15,
Organism=Homo sapiens, GI31317231, Length=103, Percent_Identity=39.8058252427184, Blast_Score=75, Evalue=1e-14,
Organism=Homo sapiens, GI33469985, Length=92, Percent_Identity=43.4782608695652, Blast_Score=74, Evalue=2e-14,
Organism=Homo sapiens, GI4503727, Length=112, Percent_Identity=40.1785714285714, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87082390, Length=113, Percent_Identity=48.6725663716814, Blast_Score=95, Evalue=1e-21,
Organism=Escherichia coli, GI1789745, Length=113, Percent_Identity=43.3628318584071, Blast_Score=78, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71993519, Length=92, Percent_Identity=56.5217391304348, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17540882, Length=93, Percent_Identity=47.3118279569892, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17561782, Length=90, Percent_Identity=51.1111111111111, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17561778, Length=99, Percent_Identity=40.4040404040404, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320727, Length=93, Percent_Identity=56.989247311828, Blast_Score=107, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6324194, Length=99, Percent_Identity=54.5454545454545, Blast_Score=104, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6323482, Length=108, Percent_Identity=47.2222222222222, Blast_Score=93, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323566, Length=108, Percent_Identity=48.1481481481481, Blast_Score=91, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281363946, Length=93, Percent_Identity=59.1397849462366, Blast_Score=116, Evalue=3e-27,
Organism=Drosophila melanogaster, GI17352457, Length=93, Percent_Identity=59.1397849462366, Blast_Score=116, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24655568, Length=108, Percent_Identity=52.7777777777778, Blast_Score=109, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24647110, Length=113, Percent_Identity=47.787610619469, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21356629, Length=94, Percent_Identity=57.4468085106383, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24583150, Length=100, Percent_Identity=45, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 12002; Mature: 11870

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTSSGLQYEDTVLGTGAIAKAGQHVKVHYTGWLYNGGTQGAKFDSSKDRGQPFEFSLG
CCCCCCCCEECCEEEECCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEECC
AGQVIRGWDEGVQGMSVGGTRRLIIPAELGYGARGAGGVIPPNATLLFEVDLLAT
CCCEEECCCCCCCCEECCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure 
TTTSSGLQYEDTVLGTGAIAKAGQHVKVHYTGWLYNGGTQGAKFDSSKDRGQPFEFSLG
CCCCCCCEECCEEEECCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEECC
AGQVIRGWDEGVQGMSVGGTRRLIIPAELGYGARGAGGVIPPNATLLFEVDLLAT
CCCEEECCCCCCCCEECCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]