| Definition | Polaromonas sp. JS666 chromosome, complete genome. |
|---|---|
| Accession | NC_007948 |
| Length | 5,200,264 |
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The map label for this gene is livF [H]
Identifier: 91788942
GI number: 91788942
Start: 3250400
End: 3251077
Strand: Reverse
Name: livF [H]
Synonym: Bpro_3082
Alternate gene names: 91788942
Gene position: 3251077-3250400 (Counterclockwise)
Preceding gene: 91788943
Following gene: 91788941
Centisome position: 62.52
GC content: 65.93
Gene sequence:
>678_bases ATGCCTGATATGCGCATGAACGTGCAAATGGACGTGCCCCTGGACGTGGAGGGGCTGAATGCCTTTTATGGCCCGGCCCA GGCGCTTTTCGGCATTTCCCTGCAGGTGCGGCAGCGGGAGTTCGTCGTGCTGCAGGGACTGAATGGCGCTGGAAAATCGA CGCTGCTGAAAGCCCTGATGGGTCTGGAGGTGCGCACCGAGGGCCGCATCAGTTACCAGACGGAAACGGGCCGCGCCGAC ATCGGTCAATGGCCGACGCACCGGCGCGCACGTGCCGGGCTGGGCTATGTGCCCGAAGACCGGCGGCTTTTCACCGGCCT GACGGTTCGCGAGAACCTGGCCGTGGCGGCAGGCCGGGACGTTGCGGCGCACGAGGCCAGGGTGCTGGATTTGTTCCCGG TGCTCAAGACCATGCTGAAACGGCCCGCTGCCCAGATGAGCGGCGGCGAGCAGCAGATGCTGGCCATTGCCCGCACGCTG ATGACCGGCCCGCGCCTGCTGCTGCTCGATGAGCCTTGCGAAGGCATTGCACCGGTGCTGGTCGAGTCCATCCGCGATGC CTTGCTGGCCCTCAGGGCGGGCGGCATGCCCATGCTGGTGGTGGAGCAAAACCAGCTGCTGGCAGCCAGTGCTGACCGGC TGGTCCGGCTGGTTGCGGGTAAAGTCAGGGGTTCGTGA
Upstream 100 bases:
>100_bases CTGGTACTGATTGAGGGCCGGCTGGCGGCGCAGGGTTCGTTTGAGGAGATTTCCCGCGACAGCACGGTGCGCAGGCGCTA TCTGGGTGAAGGCGCAGCTC
Downstream 100 bases:
>100_bases ACATGCGCTGATTTCCCCTCGCCGGCTTTCTCGCGAACCCCGGAATTTTGGCGCGATTTCCCCTTTTCTTCCTCATTTTT CAAAAAGGACATCCACATGA
Product: ABC transporter-like protein
Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]
Alternate protein names: LIV-I protein F [H]
Number of amino acids: Translated: 225; Mature: 224
Protein sequence:
>225_residues MPDMRMNVQMDVPLDVEGLNAFYGPAQALFGISLQVRQREFVVLQGLNGAGKSTLLKALMGLEVRTEGRISYQTETGRAD IGQWPTHRRARAGLGYVPEDRRLFTGLTVRENLAVAAGRDVAAHEARVLDLFPVLKTMLKRPAAQMSGGEQQMLAIARTL MTGPRLLLLDEPCEGIAPVLVESIRDALLALRAGGMPMLVVEQNQLLAASADRLVRLVAGKVRGS
Sequences:
>Translated_225_residues MPDMRMNVQMDVPLDVEGLNAFYGPAQALFGISLQVRQREFVVLQGLNGAGKSTLLKALMGLEVRTEGRISYQTETGRAD IGQWPTHRRARAGLGYVPEDRRLFTGLTVRENLAVAAGRDVAAHEARVLDLFPVLKTMLKRPAAQMSGGEQQMLAIARTL MTGPRLLLLDEPCEGIAPVLVESIRDALLALRAGGMPMLVVEQNQLLAASADRLVRLVAGKVRGS >Mature_224_residues PDMRMNVQMDVPLDVEGLNAFYGPAQALFGISLQVRQREFVVLQGLNGAGKSTLLKALMGLEVRTEGRISYQTETGRADI GQWPTHRRARAGLGYVPEDRRLFTGLTVRENLAVAAGRDVAAHEARVLDLFPVLKTMLKRPAAQMSGGEQQMLAIARTLM TGPRLLLLDEPCEGIAPVLVESIRDALLALRAGGMPMLVVEQNQLLAASADRLVRLVAGKVRGS
Specific function: Component of the leucine-specific transport system [H]
COG id: COG0410
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI153792144, Length=221, Percent_Identity=30.316742081448, Blast_Score=81, Evalue=6e-16, Organism=Homo sapiens, GI255708477, Length=204, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI31657092, Length=200, Percent_Identity=28.5, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI27436953, Length=206, Percent_Identity=27.1844660194175, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI6005701, Length=202, Percent_Identity=29.2079207920792, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI27477115, Length=202, Percent_Identity=28.7128712871287, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI21536376, Length=207, Percent_Identity=28.5024154589372, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI47078218, Length=201, Percent_Identity=28.8557213930348, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI45446740, Length=201, Percent_Identity=28.8557213930348, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI4505771, Length=207, Percent_Identity=26.5700483091787, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI9961252, Length=207, Percent_Identity=26.5700483091787, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI148612844, Length=219, Percent_Identity=28.7671232876712, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI105990541, Length=196, Percent_Identity=27.0408163265306, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI87082268, Length=216, Percent_Identity=45.3703703703704, Blast_Score=153, Evalue=9e-39, Organism=Escherichia coli, GI1789672, Length=220, Percent_Identity=32.2727272727273, Blast_Score=101, Evalue=5e-23, Organism=Escherichia coli, GI1787089, Length=219, Percent_Identity=33.7899543378995, Blast_Score=94, Evalue=9e-21, Organism=Escherichia coli, GI1789593, Length=198, Percent_Identity=32.8282828282828, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1786872, Length=219, Percent_Identity=31.5068493150685, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1790190, Length=231, Percent_Identity=31.1688311688312, Blast_Score=84, Evalue=6e-18, Organism=Escherichia coli, GI1789873, Length=212, Percent_Identity=31.1320754716981, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1787029, Length=219, Percent_Identity=30.1369863013699, Blast_Score=83, Evalue=1e-17, Organism=Escherichia coli, GI48994943, Length=220, Percent_Identity=32.7272727272727, Blast_Score=82, Evalue=2e-17, Organism=Escherichia coli, GI1787370, Length=212, Percent_Identity=31.6037735849057, Blast_Score=82, Evalue=2e-17, Organism=Escherichia coli, GI1788761, Length=221, Percent_Identity=30.316742081448, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1790467, Length=198, Percent_Identity=34.3434343434343, Blast_Score=81, Evalue=5e-17, Organism=Escherichia coli, GI1786703, Length=210, Percent_Identity=34.2857142857143, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1788225, Length=219, Percent_Identity=29.2237442922374, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI87081791, Length=165, Percent_Identity=32.7272727272727, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1787105, Length=203, Percent_Identity=31.0344827586207, Blast_Score=74, Evalue=9e-15, Organism=Escherichia coli, GI1788165, Length=170, Percent_Identity=31.7647058823529, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1787712, Length=225, Percent_Identity=28.8888888888889, Blast_Score=73, Evalue=1e-14, Organism=Escherichia coli, GI1790162, Length=224, Percent_Identity=27.2321428571429, Blast_Score=72, Evalue=2e-14, Organism=Escherichia coli, GI1790525, Length=200, Percent_Identity=30, Blast_Score=72, Evalue=2e-14, Organism=Escherichia coli, GI1786319, Length=198, Percent_Identity=34.3434343434343, Blast_Score=71, Evalue=6e-14, Organism=Escherichia coli, GI48995001, Length=224, Percent_Identity=30.3571428571429, Blast_Score=71, Evalue=7e-14, Organism=Escherichia coli, GI87081782, Length=218, Percent_Identity=29.3577981651376, Blast_Score=70, Evalue=8e-14, Organism=Escherichia coli, GI1788210, Length=218, Percent_Identity=31.651376146789, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1789864, Length=229, Percent_Identity=28.82096069869, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI1788897, Length=163, Percent_Identity=31.9018404907975, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI87081709, Length=208, Percent_Identity=29.8076923076923, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1787792, Length=183, Percent_Identity=28.4153005464481, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI87081834, Length=200, Percent_Identity=29, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI87082267, Length=219, Percent_Identity=28.7671232876712, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1788450, Length=173, Percent_Identity=29.4797687861272, Blast_Score=65, Evalue=5e-12, Organism=Escherichia coli, GI48994997, Length=225, Percent_Identity=27.5555555555556, Blast_Score=63, Evalue=1e-11, Organism=Escherichia coli, GI1789991, Length=191, Percent_Identity=29.3193717277487, Blast_Score=63, Evalue=1e-11, Organism=Escherichia coli, GI1788644, Length=225, Percent_Identity=29.3333333333333, Blast_Score=62, Evalue=2e-11, Organism=Escherichia coli, GI1787112, Length=190, Percent_Identity=33.6842105263158, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI1786654, Length=177, Percent_Identity=33.3333333333333, Blast_Score=60, Evalue=8e-11, Organism=Caenorhabditis elegans, GI25146777, Length=211, Percent_Identity=28.9099526066351, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71992285, Length=171, Percent_Identity=29.8245614035088, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI71984940, Length=206, Percent_Identity=29.126213592233, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI71996809, Length=205, Percent_Identity=29.2682926829268, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI193202349, Length=208, Percent_Identity=28.3653846153846, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17558664, Length=207, Percent_Identity=28.5024154589372, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI193211015, Length=211, Percent_Identity=27.4881516587678, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI193211017, Length=211, Percent_Identity=27.9620853080569, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17510237, Length=187, Percent_Identity=28.3422459893048, Blast_Score=64, Evalue=7e-11, Organism=Caenorhabditis elegans, GI212646699, Length=151, Percent_Identity=34.4370860927152, Blast_Score=64, Evalue=7e-11, Organism=Drosophila melanogaster, GI221512771, Length=219, Percent_Identity=27.8538812785388, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI85725262, Length=202, Percent_Identity=27.7227722772277, Blast_Score=72, Evalue=2e-13, Organism=Drosophila melanogaster, GI24582014, Length=178, Percent_Identity=30.8988764044944, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24582012, Length=178, Percent_Identity=30.8988764044944, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24666092, Length=233, Percent_Identity=26.6094420600858, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI17136662, Length=203, Percent_Identity=28.0788177339901, Blast_Score=64, Evalue=9e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 24453; Mature: 24322
Theoretical pI: Translated: 10.00; Mature: 10.00
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 4.9 %Met (Translated Protein) 5.3 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 4.5 %Met (Mature Protein) 4.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPDMRMNVQMDVPLDVEGLNAFYGPAQALFGISLQVRQREFVVLQGLNGAGKSTLLKALM CCCCEEEEEECCCCCCCCCCHHHCHHHHHHCCEEEEECCEEEEEECCCCCCHHHHHHHHH GLEVRTEGRISYQTETGRADIGQWPTHRRARAGLGYVPEDRRLFTGLTVRENLAVAAGRD CCEEECCCEEEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCEEEECCEECCCEEEECCCC VAAHEARVLDLFPVLKTMLKRPAAQMSGGEQQMLAIARTLMTGPRLLLLDEPCEGIAPVL HHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHH VESIRDALLALRAGGMPMLVVEQNQLLAASADRLVRLVAGKVRGS HHHHHHHHHHHHCCCCEEEEEECCCEEHHHHHHHHHHHHHHCCCC >Mature Secondary Structure PDMRMNVQMDVPLDVEGLNAFYGPAQALFGISLQVRQREFVVLQGLNGAGKSTLLKALM CCCEEEEEECCCCCCCCCCHHHCHHHHHHCCEEEEECCEEEEEECCCCCCHHHHHHHHH GLEVRTEGRISYQTETGRADIGQWPTHRRARAGLGYVPEDRRLFTGLTVRENLAVAAGRD CCEEECCCEEEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCEEEECCEECCCEEEECCCC VAAHEARVLDLFPVLKTMLKRPAAQMSGGEQQMLAIARTLMTGPRLLLLDEPCEGIAPVL HHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHH VESIRDALLALRAGGMPMLVVEQNQLLAASADRLVRLVAGKVRGS HHHHHHHHHHHHCCCCEEEEEECCCEEHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]
Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2195019; 8041620; 9278503 [H]