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The map label for this gene is pncB

Identifier: 91788940

GI number: 91788940

Start: 3248728

End: 3249915

Strand: Reverse

Name: pncB

Synonym: Bpro_3080

Alternate gene names: 91788940

Gene position: 3249915-3248728 (Counterclockwise)

Preceding gene: 91788941

Following gene: 91788939

Centisome position: 62.5

GC content: 60.19

Gene sequence:

>1188_bases
ATGATCATCACCAGCCTGCTTGATACCGACCTGTACAAGTTCACCATGATGCAGGTGGTGTTGCACCAGTTTCCAGGTGC
CGAGGTGGAGTACCGGTTCAAGTGCCGCAACGCCGGGGCGCCCGGCATAGGCAAGCTGGCACCTTATGTGAACGAAATCC
GCGAAGAGATCCGCGGGTTGTGCAATTTGCGCTTTCAGGATGCCGAGCTGGCCTACCTGAAGGCCATGCGCTTCATCAAG
AGCGACTTCGTCGATTTTCTGGGTATCTTCAAGCTCAACGAGAAATACGTGAGCGTGACGGCCTTGCCATCGGGCGAGAT
CGAGGTGTCCATCAAGGGCCCCTGGCTGCACACCATCCTGTTTGAAATCCCGGTGCTGGCCATCATCAATGAGGTCTACT
TTCGCAACACGCAAAAGCAGCCTGACCTGACCGAAGGCCGCAAACGCCTGGACACCAAGATACTGGAGCTGCAGGCCGAT
GGCCTGCGCGAACTCAAGATCGCCGACTACGGCACGCGCCGGCGTTTCGGCAAGGTCTGGCACGAGGAAGTGTTGCGCAC
GCTGGTGACCCGTCTGGGCACGGGCATGTCGGGCCAGCTCGCGGGGACCAGCAATGTGCTGTTTGCCATGAAGCTGGGCC
TGACGCCGCTGGGCACCATGGCGCACGAATACCTGCAGGCCTGCCAGGCGCTCGGGCCGCGCCTGCGTGACAGCCAGGTC
TTCGGTTTCGAATCGTGGGCCCGGGAGTACCGGGGTGACCTGGGGATTGCGCTGTCGGACGTATACGGCATGAGTGCCTT
CCTGCGCGATTTCGACATGTACTTCTGCAAGCTGTTTGACGGGGCGCGCCATGACAGCGGCGACCCGTTCGAGTGGGGTG
AGCGCATGCTCGCGCACTACGTTAAAAACCGCGTCGATCCCAGAACCAAGACGCTGATCTTCAGCGACGCGCTCACCGTG
CCGCGCACCATTGAGCTGTACCAGCAGTTCAGGGGGCGTTGCCAGCTGGCTTTCGGCATAGGCACCAACCTGACCAACGA
CCTGGGTTACGAGCCGCTGCAGATCGTCATCAAGATGATTCGCTGCAATGGCCAGCCGGTGGCCAAGCTGTCGGACACGC
CCTCCAAAAACATGTGCGAGGACGAAAAGTACCTGGCCTATCTGCGTCAGGTCTTCGAGATTGGCTGA

Upstream 100 bases:

>100_bases
GGCGGCGTGATCCCGCCCAATGCCACCTTGCTGTTTGAAGTCGACCTGCTGGCAACCTGAGCCTCTGCGTTTTCAGCCGC
CCCGGAGCAAAGCCGCCACC

Downstream 100 bases:

>100_bases
TGCCGGTATCCGGCGTTTCGCCAGGCGCAATGGCTACCTGGCGAGTGCCTGCCCTTGCCCGCTGGCCAGCGAGCGCGGGG
CCATGCCCGCCACGAAAACT

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MIITSLLDTDLYKFTMMQVVLHQFPGAEVEYRFKCRNAGAPGIGKLAPYVNEIREEIRGLCNLRFQDAELAYLKAMRFIK
SDFVDFLGIFKLNEKYVSVTALPSGEIEVSIKGPWLHTILFEIPVLAIINEVYFRNTQKQPDLTEGRKRLDTKILELQAD
GLRELKIADYGTRRRFGKVWHEEVLRTLVTRLGTGMSGQLAGTSNVLFAMKLGLTPLGTMAHEYLQACQALGPRLRDSQV
FGFESWAREYRGDLGIALSDVYGMSAFLRDFDMYFCKLFDGARHDSGDPFEWGERMLAHYVKNRVDPRTKTLIFSDALTV
PRTIELYQQFRGRCQLAFGIGTNLTNDLGYEPLQIVIKMIRCNGQPVAKLSDTPSKNMCEDEKYLAYLRQVFEIG

Sequences:

>Translated_395_residues
MIITSLLDTDLYKFTMMQVVLHQFPGAEVEYRFKCRNAGAPGIGKLAPYVNEIREEIRGLCNLRFQDAELAYLKAMRFIK
SDFVDFLGIFKLNEKYVSVTALPSGEIEVSIKGPWLHTILFEIPVLAIINEVYFRNTQKQPDLTEGRKRLDTKILELQAD
GLRELKIADYGTRRRFGKVWHEEVLRTLVTRLGTGMSGQLAGTSNVLFAMKLGLTPLGTMAHEYLQACQALGPRLRDSQV
FGFESWAREYRGDLGIALSDVYGMSAFLRDFDMYFCKLFDGARHDSGDPFEWGERMLAHYVKNRVDPRTKTLIFSDALTV
PRTIELYQQFRGRCQLAFGIGTNLTNDLGYEPLQIVIKMIRCNGQPVAKLSDTPSKNMCEDEKYLAYLRQVFEIG
>Mature_395_residues
MIITSLLDTDLYKFTMMQVVLHQFPGAEVEYRFKCRNAGAPGIGKLAPYVNEIREEIRGLCNLRFQDAELAYLKAMRFIK
SDFVDFLGIFKLNEKYVSVTALPSGEIEVSIKGPWLHTILFEIPVLAIINEVYFRNTQKQPDLTEGRKRLDTKILELQAD
GLRELKIADYGTRRRFGKVWHEEVLRTLVTRLGTGMSGQLAGTSNVLFAMKLGLTPLGTMAHEYLQACQALGPRLRDSQV
FGFESWAREYRGDLGIALSDVYGMSAFLRDFDMYFCKLFDGARHDSGDPFEWGERMLAHYVKNRVDPRTKTLIFSDALTV
PRTIELYQQFRGRCQLAFGIGTNLTNDLGYEPLQIVIKMIRCNGQPVAKLSDTPSKNMCEDEKYLAYLRQVFEIG

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family

Homologues:

Organism=Escherichia coli, GI1787162, Length=398, Percent_Identity=42.4623115577889, Blast_Score=336, Evalue=1e-93,
Organism=Saccharomyces cerevisiae, GI6324783, Length=404, Percent_Identity=32.4257425742574, Blast_Score=195, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PNCB_POLSJ (Q128P8)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_549892.1
- ProteinModelPortal:   Q128P8
- SMR:   Q128P8
- STRING:   Q128P8
- GeneID:   4014238
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_3080
- NMPDR:   fig|296591.1.peg.2044
- eggNOG:   COG1488
- HOGENOM:   HBG325503
- OMA:   GNTFYGK
- PhylomeDB:   Q128P8
- ProtClustDB:   PRK05321
- BioCyc:   PSP296591:BPRO_3080-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00570
- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638
- PANTHER:   PTHR11098:SF1
- PIRSF:   PIRSF000484
- TIGRFAMs:   TIGR01514

Pfam domain/function: PF04095 NAPRTase; SSF51690 Q_phspho_trans

EC number: =2.4.2.11

Molecular weight: Translated: 45100; Mature: 45100

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIITSLLDTDLYKFTMMQVVLHQFPGAEVEYRFKCRNAGAPGIGKLAPYVNEIREEIRGL
CEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
CNLRFQDAELAYLKAMRFIKSDFVDFLGIFKLNEKYVSVTALPSGEIEVSIKGPWLHTIL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCHHHHHH
FEIPVLAIINEVYFRNTQKQPDLTEGRKRLDTKILELQADGLRELKIADYGTRRRFGKVW
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHH
HEEVLRTLVTRLGTGMSGQLAGTSNVLFAMKLGLTPLGTMAHEYLQACQALGPRLRDSQV
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCC
FGFESWAREYRGDLGIALSDVYGMSAFLRDFDMYFCKLFDGARHDSGDPFEWGERMLAHY
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
VKNRVDPRTKTLIFSDALTVPRTIELYQQFRGRCQLAFGIGTNLTNDLGYEPLQIVIKMI
HHHCCCCCHHEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHH
RCNGQPVAKLSDTPSKNMCEDEKYLAYLRQVFEIG
HCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIITSLLDTDLYKFTMMQVVLHQFPGAEVEYRFKCRNAGAPGIGKLAPYVNEIREEIRGL
CEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
CNLRFQDAELAYLKAMRFIKSDFVDFLGIFKLNEKYVSVTALPSGEIEVSIKGPWLHTIL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCHHHHHH
FEIPVLAIINEVYFRNTQKQPDLTEGRKRLDTKILELQADGLRELKIADYGTRRRFGKVW
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHH
HEEVLRTLVTRLGTGMSGQLAGTSNVLFAMKLGLTPLGTMAHEYLQACQALGPRLRDSQV
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCC
FGFESWAREYRGDLGIALSDVYGMSAFLRDFDMYFCKLFDGARHDSGDPFEWGERMLAHY
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
VKNRVDPRTKTLIFSDALTVPRTIELYQQFRGRCQLAFGIGTNLTNDLGYEPLQIVIKMI
HHHCCCCCHHEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHH
RCNGQPVAKLSDTPSKNMCEDEKYLAYLRQVFEIG
HCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA