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The map label for this gene is panE [C]

Identifier: 91788789

GI number: 91788789

Start: 3091602

End: 3092543

Strand: Reverse

Name: panE [C]

Synonym: Bpro_2929

Alternate gene names: 91788789

Gene position: 3092543-3091602 (Counterclockwise)

Preceding gene: 91788790

Following gene: 91788781

Centisome position: 59.47

GC content: 68.68

Gene sequence:

>942_bases
ATGACCCAATCCCTCAAAGTCGCCGTGATGGGCGCAGGCGCCGTCGGGTGCTACTTCGGCGGCATGCTCGCTCGCGCCGG
GCACGAGGTGGTGCTGATCGCCCGGCCCCAGCATGTGGAAGCCATCGCCCGCGACGGCCTGCGCATGGAAACCAAAACCT
TCGACGAGCACGTGCGCCTGGCCGCCAGCGCAGACCCGGGCGCGGTGCAGGGCGCCAACCTGGTGCTGTTCAGCGTCAAG
TCCACCGACACCGAATCGGCCGGCGCCCAGATACGGCCGCACCTGTCGGCCGACGCCCTGGTGCTGTGCCTGCAAAACGG
CGTGGACAACGCCGACCGCCTGCGCACCGTGCTGCCGCAGCACGCCGTGGCCGCCGCAGTGGTCTATGTCGCCACCGAAA
TGGCCGGCCCCGGCCACGTCAAGCACCACGGCCGCGGCGAGCTGGTGATCGAGCCCGCCAGTTCCGCCTCCTTTTCCAGC
GAAGTCGTGGCGCAAGCCCTGATTGCCGCCGGCGTGCCGACCGAGATTTCTGGCAACGTGCGCGGCGCGCTGTGGGCCAA
GCTGATCCTCAACTGTGCCTACAACGCCGTCTCGGCCATCGCCCAGCTGCCGTATGGCAAAACGGTGCAGGGCGAGGGCG
TGAAAGACGTGATGCGCGACGTGGTGGCCGAATGCCTGGCCGTGGCCAAGGCCGAGGGCGTGCAGGTGCCCGGCGACGTG
GACGCCGCTGTGCGCAAGATCGCTGAAACCATGCCCAGCCAGTTTTCATCCACCGCGCAAGACCTGGCGCGCGGCAAGCG
CAGCGAGATCGACTACCTCAACGGCCTGATTGTGCAGCGCGGCGAGGCGCTGGGCGTTGCCACGCCGGCAAACCGGGTGT
TGTGGGCCTTGGTGAAGTTGCTGGAAGGCCAGCAATCCGCCGCGGGGTCACCCGCTCGCTAG

Upstream 100 bases:

>100_bases
GCTGGGCCGGCGCTTTGCCGGCAGCCTCGGTTAGGCGGCCTGCAAATACGGCGGACTTGACCCACAATCCTTGTCTTCGC
ATCTCTCTGAAAGCCACCTC

Downstream 100 bases:

>100_bases
CGCAGTGCCGATCATCTCCTTCCCCCGCTGGGGGAAGGCCGGGATGGGGGCTCACGGCGTGAGCGTCGGGCCACCGTGCT
GACCTGGTCGTCGCTGGCCC

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTQSLKVAVMGAGAVGCYFGGMLARAGHEVVLIARPQHVEAIARDGLRMETKTFDEHVRLAASADPGAVQGANLVLFSVK
STDTESAGAQIRPHLSADALVLCLQNGVDNADRLRTVLPQHAVAAAVVYVATEMAGPGHVKHHGRGELVIEPASSASFSS
EVVAQALIAAGVPTEISGNVRGALWAKLILNCAYNAVSAIAQLPYGKTVQGEGVKDVMRDVVAECLAVAKAEGVQVPGDV
DAAVRKIAETMPSQFSSTAQDLARGKRSEIDYLNGLIVQRGEALGVATPANRVLWALVKLLEGQQSAAGSPAR

Sequences:

>Translated_313_residues
MTQSLKVAVMGAGAVGCYFGGMLARAGHEVVLIARPQHVEAIARDGLRMETKTFDEHVRLAASADPGAVQGANLVLFSVK
STDTESAGAQIRPHLSADALVLCLQNGVDNADRLRTVLPQHAVAAAVVYVATEMAGPGHVKHHGRGELVIEPASSASFSS
EVVAQALIAAGVPTEISGNVRGALWAKLILNCAYNAVSAIAQLPYGKTVQGEGVKDVMRDVVAECLAVAKAEGVQVPGDV
DAAVRKIAETMPSQFSSTAQDLARGKRSEIDYLNGLIVQRGEALGVATPANRVLWALVKLLEGQQSAAGSPAR
>Mature_312_residues
TQSLKVAVMGAGAVGCYFGGMLARAGHEVVLIARPQHVEAIARDGLRMETKTFDEHVRLAASADPGAVQGANLVLFSVKS
TDTESAGAQIRPHLSADALVLCLQNGVDNADRLRTVLPQHAVAAAVVYVATEMAGPGHVKHHGRGELVIEPASSASFSSE
VVAQALIAAGVPTEISGNVRGALWAKLILNCAYNAVSAIAQLPYGKTVQGEGVKDVMRDVVAECLAVAKAEGVQVPGDVD
AAVRKIAETMPSQFSSTAQDLARGKRSEIDYLNGLIVQRGEALGVATPANRVLWALVKLLEGQQSAAGSPAR

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=311, Percent_Identity=26.3665594855305, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 32526; Mature: 32394

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSLKVAVMGAGAVGCYFGGMLARAGHEVVLIARPQHVEAIARDGLRMETKTFDEHVRL
CCCCEEEEEEECCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCEEHHHHHHHHHEE
AASADPGAVQGANLVLFSVKSTDTESAGAQIRPHLSADALVLCLQNGVDNADRLRTVLPQ
ECCCCCCCCCCCCEEEEEEECCCCCCCCCEECCCCCHHHHHHHHHCCCCCHHHHHHHHHH
HAVAAAVVYVATEMAGPGHVKHHGRGELVIEPASSASFSSEVVAQALIAAGVPTEISGNV
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCC
RGALWAKLILNCAYNAVSAIAQLPYGKTVQGEGVKDVMRDVVAECLAVAKAEGVQVPGDV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCH
DAAVRKIAETMPSQFSSTAQDLARGKRSEIDYLNGLIVQRGEALGVATPANRVLWALVKL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHH
LEGQQSAAGSPAR
HCCCCCCCCCCCC
>Mature Secondary Structure 
TQSLKVAVMGAGAVGCYFGGMLARAGHEVVLIARPQHVEAIARDGLRMETKTFDEHVRL
CCCEEEEEEECCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCEEHHHHHHHHHEE
AASADPGAVQGANLVLFSVKSTDTESAGAQIRPHLSADALVLCLQNGVDNADRLRTVLPQ
ECCCCCCCCCCCCEEEEEEECCCCCCCCCEECCCCCHHHHHHHHHCCCCCHHHHHHHHHH
HAVAAAVVYVATEMAGPGHVKHHGRGELVIEPASSASFSSEVVAQALIAAGVPTEISGNV
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCC
RGALWAKLILNCAYNAVSAIAQLPYGKTVQGEGVKDVMRDVVAECLAVAKAEGVQVPGDV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCH
DAAVRKIAETMPSQFSSTAQDLARGKRSEIDYLNGLIVQRGEALGVATPANRVLWALVKL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHH
LEGQQSAAGSPAR
HCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]