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The map label for this gene is rpiA

Identifier: 91788718

GI number: 91788718

Start: 3012245

End: 3012967

Strand: Reverse

Name: rpiA

Synonym: Bpro_2857

Alternate gene names: 91788718

Gene position: 3012967-3012245 (Counterclockwise)

Preceding gene: 91788721

Following gene: 91788714

Centisome position: 57.94

GC content: 60.17

Gene sequence:

>723_bases
TTGTCGCAAAAACCAACCTCTCATCCTTACAAGCCCAACATGACTCAAGACGAACTCAAAGCCCTGGTCGGCCAGGCCGC
CCTGCCATACGTGGAACCCGGCAGCATTGTCGGCGTGGGCACCGGCTCCACTGTCAACAAATTCATAGATGCACTGGCAA
CGATGAAGGACCGCATTGCCGGCGCGGTCTCCAGTTCGGTGGCGTCTACCGAACGTCTGCAGGCCATCGGCATCAAGGTG
TTTGATGCCACTGAGGTGGATGAGCTGGCCGTGTACATCGACGGAGCCGACGAGATCGACCACGCGGGCTACATGATCAA
GGGTGGTGGCGCAGCGCTCACGCGCGAAAAAATCGTGGCGGCCCAGTCACGCAAATTTGTCTGTATTGCCGACGAGTCCA
AACTGGTGCAAACGCTGGGCAGCTTTCCCTTGCCGGTGGAGGTGATTCCGATGGCCGCCAGGCGCATTGCTCGCCAGTTT
GCCGCGCTGGGCGGTACGGCGACCTTGCGGTCTAAAGGTGGAGCGGAGAGCGGCGAACCGCTGGTGACCGACAACGGCCA
GCATATTCTGGACGTGACGGGCCTGAAGATCACCGACCCCTTGGGGTTTGAGTCCCAGGTAAACCAGTGGCCAGGGGTTG
TTACGGTGGGGGTGTTTGCCTTCCAGAAGGCTCATGTGTGCCTGCTGGGGGCGTCGGACGGTGTCAGGACCCTGGTGTTT
TAA

Upstream 100 bases:

>100_bases
ACGGGCCAGGGCATAGGGGAGCAGGGACATTGGATAATTCGACTTGATTTGAAGCTACTTGCTGTGAGTTGACCGGGCGT
GGCCCGGACATCGGCTCCGA

Downstream 100 bases:

>100_bases
CCGCGGTTTTTGGCCCGAGGTGGCAAGCCAGCGTGCTTAAAACTTGATGCCGGCCGGATTATCGTTCGGCTGGGTTGCTG
CGGGAGCCGGGATTGGGCGT

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSQKPTSHPYKPNMTQDELKALVGQAALPYVEPGSIVGVGTGSTVNKFIDALATMKDRIAGAVSSSVASTERLQAIGIKV
FDATEVDELAVYIDGADEIDHAGYMIKGGGAALTREKIVAAQSRKFVCIADESKLVQTLGSFPLPVEVIPMAARRIARQF
AALGGTATLRSKGGAESGEPLVTDNGQHILDVTGLKITDPLGFESQVNQWPGVVTVGVFAFQKAHVCLLGASDGVRTLVF

Sequences:

>Translated_240_residues
MSQKPTSHPYKPNMTQDELKALVGQAALPYVEPGSIVGVGTGSTVNKFIDALATMKDRIAGAVSSSVASTERLQAIGIKV
FDATEVDELAVYIDGADEIDHAGYMIKGGGAALTREKIVAAQSRKFVCIADESKLVQTLGSFPLPVEVIPMAARRIARQF
AALGGTATLRSKGGAESGEPLVTDNGQHILDVTGLKITDPLGFESQVNQWPGVVTVGVFAFQKAHVCLLGASDGVRTLVF
>Mature_239_residues
SQKPTSHPYKPNMTQDELKALVGQAALPYVEPGSIVGVGTGSTVNKFIDALATMKDRIAGAVSSSVASTERLQAIGIKVF
DATEVDELAVYIDGADEIDHAGYMIKGGGAALTREKIVAAQSRKFVCIADESKLVQTLGSFPLPVEVIPMAARRIARQFA
ALGGTATLRSKGGAESGEPLVTDNGQHILDVTGLKITDPLGFESQVNQWPGVVTVGVFAFQKAHVCLLGASDGVRTLVF

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=229, Percent_Identity=32.7510917030568, Blast_Score=102, Evalue=3e-22,
Organism=Escherichia coli, GI1789280, Length=226, Percent_Identity=61.0619469026549, Blast_Score=264, Evalue=4e-72,
Organism=Caenorhabditis elegans, GI17551758, Length=202, Percent_Identity=37.1287128712871, Blast_Score=103, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6324669, Length=217, Percent_Identity=29.0322580645161, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI281364072, Length=217, Percent_Identity=33.1797235023041, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_POLSJ (Q129M0)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_549670.1
- ProteinModelPortal:   Q129M0
- SMR:   Q129M0
- STRING:   Q129M0
- GeneID:   4014469
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_2857
- NMPDR:   fig|296591.1.peg.5448
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- PhylomeDB:   Q129M0
- ProtClustDB:   PRK00702
- BioCyc:   PSP296591:BPRO_2857-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 25197; Mature: 25066

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKPTSHPYKPNMTQDELKALVGQAALPYVEPGSIVGVGTGSTVNKFIDALATMKDRIA
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHH
GAVSSSVASTERLQAIGIKVFDATEVDELAVYIDGADEIDHAGYMIKGGGAALTREKIVA
HHHHHHHHHHHHHHHHCEEEECCCCCCEEEEEECCCCCCCCCCEEEECCCCHHHHHHHHH
AQSRKFVCIADESKLVQTLGSFPLPVEVIPMAARRIARQFAALGGTATLRSKGGAESGEP
HCCCCEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCC
LVTDNGQHILDVTGLKITDPLGFESQVNQWPGVVTVGVFAFQKAHVCLLGASDGVRTLVF
EEECCCCEEEEECCEEEECCCCCHHHHHCCCCEEEEHHHHHCCCEEEEEECCCCCEEECC
>Mature Secondary Structure 
SQKPTSHPYKPNMTQDELKALVGQAALPYVEPGSIVGVGTGSTVNKFIDALATMKDRIA
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHH
GAVSSSVASTERLQAIGIKVFDATEVDELAVYIDGADEIDHAGYMIKGGGAALTREKIVA
HHHHHHHHHHHHHHHHCEEEECCCCCCEEEEEECCCCCCCCCCEEEECCCCHHHHHHHHH
AQSRKFVCIADESKLVQTLGSFPLPVEVIPMAARRIARQFAALGGTATLRSKGGAESGEP
HCCCCEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCC
LVTDNGQHILDVTGLKITDPLGFESQVNQWPGVVTVGVFAFQKAHVCLLGASDGVRTLVF
EEECCCCEEEEECCEEEECCCCCHHHHHCCCCEEEEHHHHHCCCEEEEEECCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA