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The map label for this gene is panE [C]

Identifier: 91788655

GI number: 91788655

Start: 2933484

End: 2934494

Strand: Direct

Name: panE [C]

Synonym: Bpro_2793

Alternate gene names: 91788655

Gene position: 2933484-2934494 (Clockwise)

Preceding gene: 91788654

Following gene: 91788657

Centisome position: 56.41

GC content: 61.52

Gene sequence:

>1011_bases
GTGAAAATTGCGATCATTGGAGCAGGAGCCATTGGCGGCTACGTGGGGGTAAAGCTGGCGCTGGCCGGCGAGGACGTCAC
CTTCATCGTGCGAGGCGCCAATCTGGAGGCCATCCGGAAAAACGGCATGAAGCTCATCATGCATGACGGTGTGGAGCATG
TGGCCTCCAGCGTCAAGGCCACCAATGACTATGCCGAAGCCGGCCCGCAGGACCTGGTGATCCTGGCGATGAAGGCTCAT
CAGGTGGAAGCCGTGGCCAAGGATCTGCCCAAGCTGTTCGGCCCCGACACGCCCGTAATAACCATGCAAAATGGCATCCC
CTACTGGTATTTCCACAAGCACGGCGGCCCTCACGAAGGCAGCCAGGTGCACAGCGTGGATCCCACGGGCATGATCACGG
AGATGATTCCGCCCAAACGAGTCATCGGCTGCGTCGTCTATCCGGCCTCAGAACTGGTAGCGCCCGGTGTGGTCAAGCAC
ATTGAAGGCGACCGCTTCCCGATCGGCGAACTGGATGGCTCGACCAGCGAGCGTGTCACACGCATTTCGGAGTGCTTTGG
CAGGGCCGGCTTCAAGGCGCCGGTGCTGGACAATATCCGCTGCGAGATCTGGCTCAAGCTGTGGGGGAACCTGACCTTCA
ACCCGATCAGCGCCCTGGCCCACTCCACCCTGGTAGATATTTGCCAGTTCCCGCTGTCGCGCGAACTGGCCGCCAGCATG
ATGCGCGAAGCGCAGGAAGTGGCCCAGAAACTGGGTATCGAATTCCGGGTGACGCTGGACAAGCGCATCGCTGGTGCCGA
GAAGGTGGGCAAGCACAAGACGTCCATGCTGCAGGATATCGAAGCCGGTCGCGCGCCCGAGATCGACGCACTCGTGGGAT
CGGTGGTGGAACTGGGCCGCCTCACGCAAACGCCGACACCCCACATTGATACCGTGTATGCGCTGGTCAGGCTGCTTGCC
AAAACCATGGAAGAAGAACGCGGCCAGGTGCGGCTTCAGCCCGCGGCCTGA

Upstream 100 bases:

>100_bases
GTGGGGGCCATGAAGCCAGGAAGCACCGTTGAAGTCGAGATTGCCGGTATCGGCAAGCTCAAAAACCGGTTCGAGTAACG
TTTTTATATTGGAGCACCGT

Downstream 100 bases:

>100_bases
AAGCGGTGCAGAAGGCTCAGGCCTGCGGCCAGGTCGTCTCGCGACGAGAGGTTTGATGCTGCAGGCCGCAAGGCTGCGCC
AGGCGGCAACATCCCCGCCA

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKIAIIGAGAIGGYVGVKLALAGEDVTFIVRGANLEAIRKNGMKLIMHDGVEHVASSVKATNDYAEAGPQDLVILAMKAH
QVEAVAKDLPKLFGPDTPVITMQNGIPYWYFHKHGGPHEGSQVHSVDPTGMITEMIPPKRVIGCVVYPASELVAPGVVKH
IEGDRFPIGELDGSTSERVTRISECFGRAGFKAPVLDNIRCEIWLKLWGNLTFNPISALAHSTLVDICQFPLSRELAASM
MREAQEVAQKLGIEFRVTLDKRIAGAEKVGKHKTSMLQDIEAGRAPEIDALVGSVVELGRLTQTPTPHIDTVYALVRLLA
KTMEEERGQVRLQPAA

Sequences:

>Translated_336_residues
MKIAIIGAGAIGGYVGVKLALAGEDVTFIVRGANLEAIRKNGMKLIMHDGVEHVASSVKATNDYAEAGPQDLVILAMKAH
QVEAVAKDLPKLFGPDTPVITMQNGIPYWYFHKHGGPHEGSQVHSVDPTGMITEMIPPKRVIGCVVYPASELVAPGVVKH
IEGDRFPIGELDGSTSERVTRISECFGRAGFKAPVLDNIRCEIWLKLWGNLTFNPISALAHSTLVDICQFPLSRELAASM
MREAQEVAQKLGIEFRVTLDKRIAGAEKVGKHKTSMLQDIEAGRAPEIDALVGSVVELGRLTQTPTPHIDTVYALVRLLA
KTMEEERGQVRLQPAA
>Mature_336_residues
MKIAIIGAGAIGGYVGVKLALAGEDVTFIVRGANLEAIRKNGMKLIMHDGVEHVASSVKATNDYAEAGPQDLVILAMKAH
QVEAVAKDLPKLFGPDTPVITMQNGIPYWYFHKHGGPHEGSQVHSVDPTGMITEMIPPKRVIGCVVYPASELVAPGVVKH
IEGDRFPIGELDGSTSERVTRISECFGRAGFKAPVLDNIRCEIWLKLWGNLTFNPISALAHSTLVDICQFPLSRELAASM
MREAQEVAQKLGIEFRVTLDKRIAGAEKVGKHKTSMLQDIEAGRAPEIDALVGSVVELGRLTQTPTPHIDTVYALVRLLA
KTMEEERGQVRLQPAA

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 36408; Mature: 36408

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIIGAGAIGGYVGVKLALAGEDVTFIVRGANLEAIRKNGMKLIMHDGVEHVASSVKA
CEEEEEECCHHCCCEEEEEEEECCCEEEEEECCCHHHHHHCCCEEEECCCHHHHHHHHHH
TNDYAEAGPQDLVILAMKAHQVEAVAKDLPKLFGPDTPVITMQNGIPYWYFHKHGGPHEG
CCHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCCCCCCC
SQVHSVDPTGMITEMIPPKRVIGCVVYPASELVAPGVVKHIEGDRFPIGELDGSTSERVT
CEEECCCCCCHHHHCCCCHHHHEEEEECHHHHHCCHHHHHCCCCCCCCCCCCCCHHHHHH
RISECFGRAGFKAPVLDNIRCEIWLKLWGNLTFNPISALAHSTLVDICQFPLSRELAASM
HHHHHHHCCCCCCCCCCCCHHEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
MREAQEVAQKLGIEFRVTLDKRIAGAEKVGKHKTSMLQDIEAGRAPEIDALVGSVVELGR
HHHHHHHHHHCCCEEEEEEHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
LTQTPTPHIDTVYALVRLLAKTMEEERGQVRLQPAA
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCC
>Mature Secondary Structure
MKIAIIGAGAIGGYVGVKLALAGEDVTFIVRGANLEAIRKNGMKLIMHDGVEHVASSVKA
CEEEEEECCHHCCCEEEEEEEECCCEEEEEECCCHHHHHHCCCEEEECCCHHHHHHHHHH
TNDYAEAGPQDLVILAMKAHQVEAVAKDLPKLFGPDTPVITMQNGIPYWYFHKHGGPHEG
CCHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCCCCCCC
SQVHSVDPTGMITEMIPPKRVIGCVVYPASELVAPGVVKHIEGDRFPIGELDGSTSERVT
CEEECCCCCCHHHHCCCCHHHHEEEEECHHHHHCCHHHHHCCCCCCCCCCCCCCHHHHHH
RISECFGRAGFKAPVLDNIRCEIWLKLWGNLTFNPISALAHSTLVDICQFPLSRELAASM
HHHHHHHCCCCCCCCCCCCHHEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
MREAQEVAQKLGIEFRVTLDKRIAGAEKVGKHKTSMLQDIEAGRAPEIDALVGSVVELGR
HHHHHHHHHHCCCEEEEEEHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
LTQTPTPHIDTVYALVRLLAKTMEEERGQVRLQPAA
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]