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The map label for this gene is ppsA [H]

Identifier: 91788619

GI number: 91788619

Start: 2900151

End: 2902628

Strand: Direct

Name: ppsA [H]

Synonym: Bpro_2757

Alternate gene names: 91788619

Gene position: 2900151-2902628 (Clockwise)

Preceding gene: 91788618

Following gene: 91788620

Centisome position: 55.77

GC content: 65.54

Gene sequence:

>2478_bases
ATGACGAAAAACTACATTCGCTGGTTTTCGGAAATCGGTGTCGCCGATGTCGCGCTGGTGGGCGGCAAGAACGCGTCGCT
GGGCGAGATGGTCCGCGAACTGGGGACGCAGAATGTGCGGGTGCCCAATGGCTTTGCGGTCACGGCCGAAGCCTATCGCT
ACGTGCTTGATCAGTCGGGGGCCTGGCCAGGCCTGCACGATGCACTCGACGGCCTGGACGTCAAGGACGTCGATGACCTG
GCGCGGCGCGCACAGCGGGCGCGCGAGATCATCCAGGCCGCGCCGTTGCCCGAGGACCTTGTCGCCGGGATCGCCGCAGC
CTACACCCGACTGCAGACCGAGTACGGCGAAGGGTTGACAGTGGCCGTGCGCAGCTCGGCGACCGCCGAAGACCTGCCGA
CCGCCAGCTTTGCCGGCCAGCACGAAACCTTTCTGAACATCTCGGGACAGGCGCGCCTGCTTGATGCGGTCCGCCAGTGC
TTTGCCAGCCTGTTCAAGGACCGGGCCATCGCCTACCGCGTTGACCATGGCATCGATCATTTCAGGGTGTTCCAGTCGGT
GGGCGTGATGAAGATGGTGCGCGCCGACCGCGCCGCCAGCGGCGTGATCTTCACCCTCGACACCGAGACCGGATTTCGCG
ACGTGGTTTTCGTCACCGGCGCCTACGGGCTGGGCGAGAACGTGGTGCAGGGCACGGTCGACCCGGACGAGTTTTATGTG
TTCAAGCCCACCCTGCGGCAGGGCCACCGGGTCGTGCTCAGGCGCAAGCTCGGCGGCAAGGAAATTCGCATGGTCTATGC
CCGGGCTGCCGGCCGCGAGACCACGCGCAACATGCCGACACCGCCGGAGGACCAGGCGCGTTATTGCATCAGCGACGATG
AGGTGCTGGAACTTGCCGACGCCGCGATCAGGATCGAAGACCACTACAGCCGCAAGTCCGGCCACCCGACACCCATGGAC
ATTGAATGGGCCAAGGATGGCCTGGACGGCAAGCTCTATATCGTCCAGGCGCGGCCAGAAACCGTGGCCTCGCGCAAACC
GCTGGGAACCATCGACGAATACCGGCTGGGCGGCAAGGGTGCGCTGCGCGTCAGCGGCCGCGCCGTGGGCAGCAAGATCG
CCTCGGGGCGGGCGCGCGTCATCAGCGACGTCGGCGAGCTCAACCAGTTCCAGCCCGGCGAGGTGCTGGTGGCGGACACG
ACCATGCCCGACTGGGGCACGGTAATGAAGATAGCCGCCGCCGTGGTGACCAACCGGGGCGGGCGGACCTGCCACGCGGC
CATCGTTGCGCGCGAAATGGGTATTCCGGCGGTGGTCGGCTGCGGCCAGGCCACCACCGCGATCCGCACCGGTGACGAGA
TCACGGTGTCCTGCGCCGAAGGCAGCGAGGGCCGGGTCTACGCCGGGCTGTTGCCCTTCACGACAACGCACCTCGACGTG
ACCGGCCTGCCCAGGCCGCAGACACACATGATGGTCAACATCGCCAACCCCGACACCGCGTTCCAGACCGCGCTGCTGCC
CAACGACGGCGTCGGCCTGGCGCGCATGGAGTTCATCGTCGCCGAACACATCCGCGCCCACCCGATGGCGCTGGTACACC
CTGAAAAAATCGAGGATGCCTCGGTACGCGAGGAAATCGCCCGCCTCACGCGTTCGTATGCCAAGCCGGCCGACTATTTC
GTCCGGCAGTTGTCTGAAGGCGTGGCCACCATTGCCGCGGCCTTCTGGCCCAAGCCGGTGATTGTGCGCATGTCCGACTT
CAAGACCAATGAATACGCGAGCCTGCTCGGCGGACGCTGGTTCGAGCCGGTCGAAGCCAATCCCATGATCGGCTTTCGCG
GTGCCTCGCGTTATGCGCACCCGGCCTATGCCGAGGGCTTCGCGCTGGAGTGCGCGGCCATGAAACGGGTGCGCGACGAG
ATGGGCCTGTCCAACGTCAGGTTGATGATCCCGTTTTGCCGCCGTGTCGAGGAAGGCGAGCGCGTGCTGCAGGCCATGGC
CGGATACGGCCTGGCACGCGGCGGTCATGAAGCTGGCAAGGGGCTGGAAATTTACGTCATGTGCGAGATCCCCAACAACG
TGATCCAGATCGATGCGTTTGCCCGGCTGTTCGACGGTTTCTCCATCGGCTCCAACGACCTGACGCAACTGGCGCTCGGG
GTGGACCGCGACTCCGACATCGTGGCCTTCGACTTCGACGAACGTGACCCGGGCGTCAAAATGCTGATTCGCCAGACCAT
AGAGGGCGCGCGGCGCAATCACCGCCACGTGGGTATTTGCGGCCAGGCGCCCTCGGACTACCCCGAAATCGCAGAATATC
TGGTAGAACTCGGCATCGACTCGATGAGCGTCACCCCGGATACGCTAATGAAAATCACGCGCGACGTGCTGGCCGTGGAA
GCACGGCTGGGACGCGCGCCACGCAGCGCCGCGCCGGCGCGACATGAGCCGTCATCGGCGGCCAGGAGCATGCCATGA

Upstream 100 bases:

>100_bases
CTGGCGCAATACAGCGCCGCCCCGTTGCGCCTACCGTATGCCAAGGTAAAGGCAACAGCAACAACAACAGGAGACTGGCT
GGCATCCGGCCACCCCCGTC

Downstream 100 bases:

>100_bases
GCAAAAAAATATCGTCATTGATGCACCGTGAAGTGTGCCTGGTCGGCCTGGACGACACGGCGCAATCCGTCGAGGCCCAG
ATGGTGGCCAAGGGCCTGTC

Product: phosphoenolpyruvate synthase

Products: NA

Alternate protein names: PEP synthase; Pyruvate, water dikinase [H]

Number of amino acids: Translated: 825; Mature: 824

Protein sequence:

>825_residues
MTKNYIRWFSEIGVADVALVGGKNASLGEMVRELGTQNVRVPNGFAVTAEAYRYVLDQSGAWPGLHDALDGLDVKDVDDL
ARRAQRAREIIQAAPLPEDLVAGIAAAYTRLQTEYGEGLTVAVRSSATAEDLPTASFAGQHETFLNISGQARLLDAVRQC
FASLFKDRAIAYRVDHGIDHFRVFQSVGVMKMVRADRAASGVIFTLDTETGFRDVVFVTGAYGLGENVVQGTVDPDEFYV
FKPTLRQGHRVVLRRKLGGKEIRMVYARAAGRETTRNMPTPPEDQARYCISDDEVLELADAAIRIEDHYSRKSGHPTPMD
IEWAKDGLDGKLYIVQARPETVASRKPLGTIDEYRLGGKGALRVSGRAVGSKIASGRARVISDVGELNQFQPGEVLVADT
TMPDWGTVMKIAAAVVTNRGGRTCHAAIVAREMGIPAVVGCGQATTAIRTGDEITVSCAEGSEGRVYAGLLPFTTTHLDV
TGLPRPQTHMMVNIANPDTAFQTALLPNDGVGLARMEFIVAEHIRAHPMALVHPEKIEDASVREEIARLTRSYAKPADYF
VRQLSEGVATIAAAFWPKPVIVRMSDFKTNEYASLLGGRWFEPVEANPMIGFRGASRYAHPAYAEGFALECAAMKRVRDE
MGLSNVRLMIPFCRRVEEGERVLQAMAGYGLARGGHEAGKGLEIYVMCEIPNNVIQIDAFARLFDGFSIGSNDLTQLALG
VDRDSDIVAFDFDERDPGVKMLIRQTIEGARRNHRHVGICGQAPSDYPEIAEYLVELGIDSMSVTPDTLMKITRDVLAVE
ARLGRAPRSAAPARHEPSSAARSMP

Sequences:

>Translated_825_residues
MTKNYIRWFSEIGVADVALVGGKNASLGEMVRELGTQNVRVPNGFAVTAEAYRYVLDQSGAWPGLHDALDGLDVKDVDDL
ARRAQRAREIIQAAPLPEDLVAGIAAAYTRLQTEYGEGLTVAVRSSATAEDLPTASFAGQHETFLNISGQARLLDAVRQC
FASLFKDRAIAYRVDHGIDHFRVFQSVGVMKMVRADRAASGVIFTLDTETGFRDVVFVTGAYGLGENVVQGTVDPDEFYV
FKPTLRQGHRVVLRRKLGGKEIRMVYARAAGRETTRNMPTPPEDQARYCISDDEVLELADAAIRIEDHYSRKSGHPTPMD
IEWAKDGLDGKLYIVQARPETVASRKPLGTIDEYRLGGKGALRVSGRAVGSKIASGRARVISDVGELNQFQPGEVLVADT
TMPDWGTVMKIAAAVVTNRGGRTCHAAIVAREMGIPAVVGCGQATTAIRTGDEITVSCAEGSEGRVYAGLLPFTTTHLDV
TGLPRPQTHMMVNIANPDTAFQTALLPNDGVGLARMEFIVAEHIRAHPMALVHPEKIEDASVREEIARLTRSYAKPADYF
VRQLSEGVATIAAAFWPKPVIVRMSDFKTNEYASLLGGRWFEPVEANPMIGFRGASRYAHPAYAEGFALECAAMKRVRDE
MGLSNVRLMIPFCRRVEEGERVLQAMAGYGLARGGHEAGKGLEIYVMCEIPNNVIQIDAFARLFDGFSIGSNDLTQLALG
VDRDSDIVAFDFDERDPGVKMLIRQTIEGARRNHRHVGICGQAPSDYPEIAEYLVELGIDSMSVTPDTLMKITRDVLAVE
ARLGRAPRSAAPARHEPSSAARSMP
>Mature_824_residues
TKNYIRWFSEIGVADVALVGGKNASLGEMVRELGTQNVRVPNGFAVTAEAYRYVLDQSGAWPGLHDALDGLDVKDVDDLA
RRAQRAREIIQAAPLPEDLVAGIAAAYTRLQTEYGEGLTVAVRSSATAEDLPTASFAGQHETFLNISGQARLLDAVRQCF
ASLFKDRAIAYRVDHGIDHFRVFQSVGVMKMVRADRAASGVIFTLDTETGFRDVVFVTGAYGLGENVVQGTVDPDEFYVF
KPTLRQGHRVVLRRKLGGKEIRMVYARAAGRETTRNMPTPPEDQARYCISDDEVLELADAAIRIEDHYSRKSGHPTPMDI
EWAKDGLDGKLYIVQARPETVASRKPLGTIDEYRLGGKGALRVSGRAVGSKIASGRARVISDVGELNQFQPGEVLVADTT
MPDWGTVMKIAAAVVTNRGGRTCHAAIVAREMGIPAVVGCGQATTAIRTGDEITVSCAEGSEGRVYAGLLPFTTTHLDVT
GLPRPQTHMMVNIANPDTAFQTALLPNDGVGLARMEFIVAEHIRAHPMALVHPEKIEDASVREEIARLTRSYAKPADYFV
RQLSEGVATIAAAFWPKPVIVRMSDFKTNEYASLLGGRWFEPVEANPMIGFRGASRYAHPAYAEGFALECAAMKRVRDEM
GLSNVRLMIPFCRRVEEGERVLQAMAGYGLARGGHEAGKGLEIYVMCEIPNNVIQIDAFARLFDGFSIGSNDLTQLALGV
DRDSDIVAFDFDERDPGVKMLIRQTIEGARRNHRHVGICGQAPSDYPEIAEYLVELGIDSMSVTPDTLMKITRDVLAVEA
RLGRAPRSAAPARHEPSSAARSMP

Specific function: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate [H]

COG id: COG0574

COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEP-utilizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1787994, Length=788, Percent_Identity=51.2690355329949, Blast_Score=803, Evalue=0.0,
Organism=Escherichia coli, GI1788756, Length=444, Percent_Identity=24.0990990990991, Blast_Score=94, Evalue=5e-20,
Organism=Escherichia coli, GI1788726, Length=187, Percent_Identity=29.9465240641711, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI48994992, Length=187, Percent_Identity=28.3422459893048, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1789193, Length=394, Percent_Identity=24.3654822335025, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17564524, Length=256, Percent_Identity=27.734375, Blast_Score=76, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR008279
- InterPro:   IPR006319
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR002192
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF01326 PPDK_N [H]

EC number: =2.7.9.2 [H]

Molecular weight: Translated: 90007; Mature: 89875

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00370 PEP_ENZYMES_PHOS_SITE ; PS00742 PEP_ENZYMES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKNYIRWFSEIGVADVALVGGKNASLGEMVRELGTQNVRVPNGFAVTAEAYRYVLDQSG
CCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCCCEECCCCEEEHHHHHHHHHHCCC
AWPGLHDALDGLDVKDVDDLARRAQRAREIIQAAPLPEDLVAGIAAAYTRLQTEYGEGLT
CCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEE
VAVRSSATAEDLPTASFAGQHETFLNISGQARLLDAVRQCFASLFKDRAIAYRVDHGIDH
EEEECCCCHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCHH
FRVFQSVGVMKMVRADRAASGVIFTLDTETGFRDVVFVTGAYGLGENVVQGTVDPDEFYV
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCHHEECCCCCCCEEE
FKPTLRQGHRVVLRRKLGGKEIRMVYARAAGRETTRNMPTPPEDQARYCISDDEVLELAD
ECCCHHCCHHEEHHHHCCCCEEEEEEEHHCCCHHCCCCCCCCCHHCCEECCCHHHHHHHH
AAIRIEDHYSRKSGHPTPMDIEWAKDGLDGKLYIVQARPETVASRKPLGTIDEYRLGGKG
HHEEEEHHHCCCCCCCCCCCCHHHCCCCCCEEEEEEECCHHHHCCCCCCCCHHHCCCCCC
ALRVSGRAVGSKIASGRARVISDVGELNQFQPGEVLVADTTMPDWGTVMKIAAAVVTNRG
EEEECCHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCC
GRTCHAAIVAREMGIPAVVGCGQATTAIRTGDEITVSCAEGSEGRVYAGLLPFTTTHLDV
CCCHHHHHHHHHCCCCEEEECCCCHHEEECCCEEEEEECCCCCCCEEEEECCCEEEEEEE
TGLPRPQTHMMVNIANPDTAFQTALLPNDGVGLARMEFIVAEHIRAHPMALVHPEKIEDA
CCCCCCCCEEEEEECCCCCHHEEEECCCCCCCHHHHHHHHHHHHHHCCEEEECCHHCCCH
SVREEIARLTRSYAKPADYFVRQLSEGVATIAAAFWPKPVIVRMSDFKTNEYASLLGGRW
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCC
FEPVEANPMIGFRGASRYAHPAYAEGFALECAAMKRVRDEMGLSNVRLMIPFCRRVEEGE
CCCCCCCCCEEECCCCCCCCCCHHCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHH
RVLQAMAGYGLARGGHEAGKGLEIYVMCEIPNNVIQIDAFARLFDGFSIGSNDLTQLALG
HHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCEEEHHHHHHHHCCCCCCCCHHHHHHCC
VDRDSDIVAFDFDERDPGVKMLIRQTIEGARRNHRHVGICGQAPSDYPEIAEYLVELGID
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCC
SMSVTPDTLMKITRDVLAVEARLGRAPRSAAPARHEPSSAARSMP
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCC
>Mature Secondary Structure 
TKNYIRWFSEIGVADVALVGGKNASLGEMVRELGTQNVRVPNGFAVTAEAYRYVLDQSG
CCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCCCEECCCCEEEHHHHHHHHHHCCC
AWPGLHDALDGLDVKDVDDLARRAQRAREIIQAAPLPEDLVAGIAAAYTRLQTEYGEGLT
CCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEE
VAVRSSATAEDLPTASFAGQHETFLNISGQARLLDAVRQCFASLFKDRAIAYRVDHGIDH
EEEECCCCHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCHH
FRVFQSVGVMKMVRADRAASGVIFTLDTETGFRDVVFVTGAYGLGENVVQGTVDPDEFYV
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCHHEECCCCCCCEEE
FKPTLRQGHRVVLRRKLGGKEIRMVYARAAGRETTRNMPTPPEDQARYCISDDEVLELAD
ECCCHHCCHHEEHHHHCCCCEEEEEEEHHCCCHHCCCCCCCCCHHCCEECCCHHHHHHHH
AAIRIEDHYSRKSGHPTPMDIEWAKDGLDGKLYIVQARPETVASRKPLGTIDEYRLGGKG
HHEEEEHHHCCCCCCCCCCCCHHHCCCCCCEEEEEEECCHHHHCCCCCCCCHHHCCCCCC
ALRVSGRAVGSKIASGRARVISDVGELNQFQPGEVLVADTTMPDWGTVMKIAAAVVTNRG
EEEECCHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCC
GRTCHAAIVAREMGIPAVVGCGQATTAIRTGDEITVSCAEGSEGRVYAGLLPFTTTHLDV
CCCHHHHHHHHHCCCCEEEECCCCHHEEECCCEEEEEECCCCCCCEEEEECCCEEEEEEE
TGLPRPQTHMMVNIANPDTAFQTALLPNDGVGLARMEFIVAEHIRAHPMALVHPEKIEDA
CCCCCCCCEEEEEECCCCCHHEEEECCCCCCCHHHHHHHHHHHHHHCCEEEECCHHCCCH
SVREEIARLTRSYAKPADYFVRQLSEGVATIAAAFWPKPVIVRMSDFKTNEYASLLGGRW
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCC
FEPVEANPMIGFRGASRYAHPAYAEGFALECAAMKRVRDEMGLSNVRLMIPFCRRVEEGE
CCCCCCCCCEEECCCCCCCCCCHHCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHH
RVLQAMAGYGLARGGHEAGKGLEIYVMCEIPNNVIQIDAFARLFDGFSIGSNDLTQLALG
HHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCEEEHHHHHHHHCCCCCCCCHHHHHHCC
VDRDSDIVAFDFDERDPGVKMLIRQTIEGARRNHRHVGICGQAPSDYPEIAEYLVELGID
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCC
SMSVTPDTLMKITRDVLAVEARLGRAPRSAAPARHEPSSAARSMP
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]