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The map label for this gene is vgb [H]

Identifier: 91788600

GI number: 91788600

Start: 2880678

End: 2881757

Strand: Direct

Name: vgb [H]

Synonym: Bpro_2738

Alternate gene names: 91788600

Gene position: 2880678-2881757 (Clockwise)

Preceding gene: 91788599

Following gene: 91788602

Centisome position: 55.39

GC content: 68.52

Gene sequence:

>1080_bases
ATGGCACTGCCAACGCAACCTCAACAAGTACGTATCAGCCGCCGCGCCGCACTGGGCGCAGTGGCGGCACTGCCCGGCCT
CTCGGGTATTGCCCTGGGTGGGGTCTTCGCAGGCGCCCTGCTCTCGCCCGCCACCGGGCACGCACAGACAACGGGCACCT
CTCGCCTGCAATCCTGGCCGCTCAACACCCCGCGCAGCACAGGCATTCACGACGTGGCGCCCGCGACCGGTGGCGGGGTC
TGGTTCTCGGCGCAGCGCAGCGGGCACCTGGGCTGGTTTGACCCGCGCACCGGCAAGTCCGAGCTGATCGCCCTGGGAAG
CAATGGCGGCAGTTCGTCGCCGCATGGCGTCATTGCCGGGCCCGACGGCGCAGCCTGGCTGACCGACAGCGGACAAAACG
CCATTGCGCGCGTGAGCTGGCCGGCGCGAGAGGTGAAGCTCTTCCCCCTGCCCGCCGGAACACCCTACGCCAACCTCAAC
ACCTGCGCCTTTGATGGCGGCGGCGACCTGTGGTTTACCGGGCAAGGCGGCTACGTGGGCAAGGTGGCCGTGCGCACCGG
CAAGGTCAGCGTGAAGGAAGCGCCACGCGGGCGCGGGCCCTACGGCATTTGCGCCACTCCAAAGGGCGACGTGTGGTGGT
GCTCGCTGGCCGGGTCCTTCATTGCGCAGATAGACCGGAGCACCGGCGAGTCACGCGTCGTTGAACCACCCACACAGCGC
CAGGGCGCGCGCCGCGTCTGGTCCGACAGCCGCGGCCGCATCTGGGTGGCCGAGTGGAACAGCGGCAACCTCTCGGTGCA
CGACCCGGCATTGGGCCTCGGCCCCAACAGCTGGCGCACCTGGAAAGCACCGGGCGCCAGCCCGCAGATCTACGCCGTGT
ATGTAGACGACAAAGACATCGTCTGGACCTCCGAGTGGAGCAACAACGCCATGCTGCGCTTCGACCCGCGCGCCGAGAAG
TTCGACGTGATCCCCATGCACCGCCCCGCGGCCAACATCCGCCAGATACTCGGCCGGCCGGGCGAAGTCTGGCTGCCCGA
AAGCGGCACGGAGTTTATTTCGGTGATCAGGACGGGGTGA

Upstream 100 bases:

>100_bases
AGGTGCACCCTTGCAGCCCTTGCATGCGGCAGCACATTGCCGCCACAATGATCCCGCACGACCTTGTCCAACCAGTCCCG
AACGCGCAGGAGAATCTGCC

Downstream 100 bases:

>100_bases
ATACCGCGAAAACTACAACGTTGATTTGTCATTGCGGGCTTGACCCGCAATCCATGGACCCCGGATCGAGTCCGGGATGA
CAAGTCAGGGGCAAGGGTTT

Product: twin-arginine translocation pathway signal protein

Products: NA

Alternate protein names: Streptogramin B lyase [H]

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MALPTQPQQVRISRRAALGAVAALPGLSGIALGGVFAGALLSPATGHAQTTGTSRLQSWPLNTPRSTGIHDVAPATGGGV
WFSAQRSGHLGWFDPRTGKSELIALGSNGGSSSPHGVIAGPDGAAWLTDSGQNAIARVSWPAREVKLFPLPAGTPYANLN
TCAFDGGGDLWFTGQGGYVGKVAVRTGKVSVKEAPRGRGPYGICATPKGDVWWCSLAGSFIAQIDRSTGESRVVEPPTQR
QGARRVWSDSRGRIWVAEWNSGNLSVHDPALGLGPNSWRTWKAPGASPQIYAVYVDDKDIVWTSEWSNNAMLRFDPRAEK
FDVIPMHRPAANIRQILGRPGEVWLPESGTEFISVIRTG

Sequences:

>Translated_359_residues
MALPTQPQQVRISRRAALGAVAALPGLSGIALGGVFAGALLSPATGHAQTTGTSRLQSWPLNTPRSTGIHDVAPATGGGV
WFSAQRSGHLGWFDPRTGKSELIALGSNGGSSSPHGVIAGPDGAAWLTDSGQNAIARVSWPAREVKLFPLPAGTPYANLN
TCAFDGGGDLWFTGQGGYVGKVAVRTGKVSVKEAPRGRGPYGICATPKGDVWWCSLAGSFIAQIDRSTGESRVVEPPTQR
QGARRVWSDSRGRIWVAEWNSGNLSVHDPALGLGPNSWRTWKAPGASPQIYAVYVDDKDIVWTSEWSNNAMLRFDPRAEK
FDVIPMHRPAANIRQILGRPGEVWLPESGTEFISVIRTG
>Mature_358_residues
ALPTQPQQVRISRRAALGAVAALPGLSGIALGGVFAGALLSPATGHAQTTGTSRLQSWPLNTPRSTGIHDVAPATGGGVW
FSAQRSGHLGWFDPRTGKSELIALGSNGGSSSPHGVIAGPDGAAWLTDSGQNAIARVSWPAREVKLFPLPAGTPYANLNT
CAFDGGGDLWFTGQGGYVGKVAVRTGKVSVKEAPRGRGPYGICATPKGDVWWCSLAGSFIAQIDRSTGESRVVEPPTQRQ
GARRVWSDSRGRIWVAEWNSGNLSVHDPALGLGPNSWRTWKAPGASPQIYAVYVDDKDIVWTSEWSNNAMLRFDPRAEKF
DVIPMHRPAANIRQILGRPGEVWLPESGTEFISVIRTG

Specific function: Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid [H]

COG id: COG4257

COG function: function code V; Streptogramin lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the vgb family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011217 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 38119; Mature: 37988

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALPTQPQQVRISRRAALGAVAALPGLSGIALGGVFAGALLSPATGHAQTTGTSRLQSWP
CCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCC
LNTPRSTGIHDVAPATGGGVWFSAQRSGHLGWFDPRTGKSELIALGSNGGSSSPHGVIAG
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEC
PDGAAWLTDSGQNAIARVSWPAREVKLFPLPAGTPYANLNTCAFDGGGDLWFTGQGGYVG
CCCCEEEECCCCCCEEEEECCCCEEEEEECCCCCCCCCCEEEEECCCCCEEEECCCCEEE
KVAVRTGKVSVKEAPRGRGPYGICATPKGDVWWCSLAGSFIAQIDRSTGESRVVEPPTQR
EEEEEECCEEEECCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHCCCCCCEEECCCHHH
QGARRVWSDSRGRIWVAEWNSGNLSVHDPALGLGPNSWRTWKAPGASPQIYAVYVDDKDI
HHHHHHHCCCCCEEEEEEECCCCEEEECCCCCCCCCCCEEEECCCCCCEEEEEEECCCCE
VWTSEWSNNAMLRFDPRAEKFDVIPMHRPAANIRQILGRPGEVWLPESGTEFISVIRTG
EEECCCCCCCEEEECCCCCCEEEEECCCCHHHHHHHHCCCCCEEECCCCCCEEEEEECC
>Mature Secondary Structure 
ALPTQPQQVRISRRAALGAVAALPGLSGIALGGVFAGALLSPATGHAQTTGTSRLQSWP
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCC
LNTPRSTGIHDVAPATGGGVWFSAQRSGHLGWFDPRTGKSELIALGSNGGSSSPHGVIAG
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEC
PDGAAWLTDSGQNAIARVSWPAREVKLFPLPAGTPYANLNTCAFDGGGDLWFTGQGGYVG
CCCCEEEECCCCCCEEEEECCCCEEEEEECCCCCCCCCCEEEEECCCCCEEEECCCCEEE
KVAVRTGKVSVKEAPRGRGPYGICATPKGDVWWCSLAGSFIAQIDRSTGESRVVEPPTQR
EEEEEECCEEEECCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHCCCCCCEEECCCHHH
QGARRVWSDSRGRIWVAEWNSGNLSVHDPALGLGPNSWRTWKAPGASPQIYAVYVDDKDI
HHHHHHHCCCCCEEEEEEECCCCEEEECCCCCCCCCCCEEEECCCCCCEEEEEEECCCCE
VWTSEWSNNAMLRFDPRAEKFDVIPMHRPAANIRQILGRPGEVWLPESGTEFISVIRTG
EEECCCCCCCEEEECCCCCCEEEEECCCCHHHHHHHHCCCCCEEECCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA