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The map label for this gene is ppa [H]

Identifier: 91788169

GI number: 91788169

Start: 2395522

End: 2396061

Strand: Direct

Name: ppa [H]

Synonym: Bpro_2300

Alternate gene names: 91788169

Gene position: 2395522-2396061 (Clockwise)

Preceding gene: 91788164

Following gene: 91788173

Centisome position: 46.07

GC content: 53.7

Gene sequence:

>540_bases
ATGTCCCTAGATAAAGTTTCTCCCGGAAAAAACGTTCCTGATTCCTTCAATGTGATCATCGAAATCCCGATGAACGCTGA
CCCGGTGAAATATGAAGTCGACAAGGAGTCGGGCGCGATTTTTGTGGACCGCTTCATGAGCACGTCCATGCACTACCCGA
CCAATTACGGTTATGTGCCCAAAACCATCAGCGGTGACGGTGACCCCGTGGATGTGCTGGTCATCACGCCCGTGCCGCTG
ATTCCCGGCGTGGTGGTGACATGCCGCGTGATCGGCATTTTAAAAATGACCGATGAGGCTGGCGAAGACGGCAAGGTGCT
GGCCGTGCCCATCGACAAGAAGTGCTCGCTCTATAGCCATTGGCAAAAGCCTGAAGACATGAACCCGTTGCGCCTGAAAA
CCATCGCGCATTTCTTTGAGCACTACAAAGACCTGGAAGAGGGCAAATGGGTCAAAGTGCAGGGATGGGAAGGCCCGGAG
GCTGCGAAGAAGGAAATTACCGACGGCATTGCCAATTACGCCAAGGCGAACAAGGCCTGA

Upstream 100 bases:

>100_bases
GAGTAGCTAAATCCAGCGGTTGACTCCCTCAACCAACGCCGCCTGCTGCAACGTTTCGTGTTCTTGTCTTTCCCTTTCTT
TTTATCAACATCAATCGACC

Downstream 100 bases:

>100_bases
GGTCCGGCAACTCACCTGATTGAATTTACCCAATCAAAAGCCAAAAGCCAAAAGCCAAAAGCGCGTGTACCCTCATCGGT
ACAGGCGCTTTTTCTTTTGG

Product: inorganic diphosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MSLDKVSPGKNVPDSFNVIIEIPMNADPVKYEVDKESGAIFVDRFMSTSMHYPTNYGYVPKTISGDGDPVDVLVITPVPL
IPGVVVTCRVIGILKMTDEAGEDGKVLAVPIDKKCSLYSHWQKPEDMNPLRLKTIAHFFEHYKDLEEGKWVKVQGWEGPE
AAKKEITDGIANYAKANKA

Sequences:

>Translated_179_residues
MSLDKVSPGKNVPDSFNVIIEIPMNADPVKYEVDKESGAIFVDRFMSTSMHYPTNYGYVPKTISGDGDPVDVLVITPVPL
IPGVVVTCRVIGILKMTDEAGEDGKVLAVPIDKKCSLYSHWQKPEDMNPLRLKTIAHFFEHYKDLEEGKWVKVQGWEGPE
AAKKEITDGIANYAKANKA
>Mature_178_residues
SLDKVSPGKNVPDSFNVIIEIPMNADPVKYEVDKESGAIFVDRFMSTSMHYPTNYGYVPKTISGDGDPVDVLVITPVPLI
PGVVVTCRVIGILKMTDEAGEDGKVLAVPIDKKCSLYSHWQKPEDMNPLRLKTIAHFFEHYKDLEEGKWVKVQGWEGPEA
AKKEITDGIANYAKANKA

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=176, Percent_Identity=61.9318181818182, Blast_Score=221, Evalue=2e-59,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 19837; Mature: 19706

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDKVSPGKNVPDSFNVIIEIPMNADPVKYEVDKESGAIFVDRFMSTSMHYPTNYGYVP
CCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCEEEEHHHHCCCCCCCCCCCCC
KTISGDGDPVDVLVITPVPLIPGVVVTCRVIGILKMTDEAGEDGKVLAVPIDKKCSLYSH
CEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHEEECCCCCCCCCEEEEECCCCCCHHHH
WQKPEDMNPLRLKTIAHFFEHYKDLEEGKWVKVQGWEGPEAAKKEITDGIANYAKANKA
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLDKVSPGKNVPDSFNVIIEIPMNADPVKYEVDKESGAIFVDRFMSTSMHYPTNYGYVP
CCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCEEEEHHHHCCCCCCCCCCCCC
KTISGDGDPVDVLVITPVPLIPGVVVTCRVIGILKMTDEAGEDGKVLAVPIDKKCSLYSH
CEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHEEECCCCCCCCCEEEEECCCCCCHHHH
WQKPEDMNPLRLKTIAHFFEHYKDLEEGKWVKVQGWEGPEAAKKEITDGIANYAKANKA
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9423859 [H]