Click here to switch to the map view.

The map label for this gene is aphA [H]

Identifier: 91787694

GI number: 91787694

Start: 1878092

End: 1879792

Strand: Reverse

Name: aphA [H]

Synonym: Bpro_1814

Alternate gene names: 91787694

Gene position: 1879792-1878092 (Counterclockwise)

Preceding gene: 91787699

Following gene: 91787693

Centisome position: 36.15

GC content: 58.91

Gene sequence:

>1701_bases
ATGCCTTCTGCTGAGCCCTCTCCAGTTGCTTCACCCGCTCCACCCGCGCACATCCTGATCGCAGAAGACAGTGGCGTGCA
GGCCTACATGCTGCGCCGCCTCCTCGAAGAAGAAGGCTACGCAACCAGCGTTGCGAAAAACGGCCGGCTCGCCCTGGAAC
TGGCTGCCCGGATACGCCCCTCACTGCTTGTCAGCGACGTCAACATGCCGGAGATGAGCGGCTACGAGCTGTGCCGGCAG
ATCAAGGCCAACCCCGATCTTTGCCATATTCCGGTGATTCTGGTGACCAACCTGTCGGACCCCGATGACGTGTTGCTCGG
GCTCAAAAGCGGCGCTGACAGCTTTGTCATCAAACCCTATGACCGAACCCATATGCTGGCGCGCGTGCAGCATGCGCTCA
GCAACCAGCACCTTCGCTCCACCGCAGAAGAAGGCCCGGGGGTGGAGATCTCCTTCCATGGCGAGAAGCACCAGATTACG
GCCAGCCGTGCCCAAATCCTCAACCTGCTGATGTCGACTTACGAAACCACCGCCCAGCGCAACAGGGAACTTCACGAAAG
CCGTGAGGAACTGGCCAAACGCACCACCGAGCTGCTGGCGGCAAACCGTTTCCTCGACTCGATCATCGAGAACATTCCGA
ACATGATCTTTATCAAGGATGCTGCGGAATTGAAGTTTGTCAGGCTCAATCGGGCGGGCGAGAACCTGCTTGGTTATTCG
CGCGACCAGTTGCTCGGAAAAAGTGACCATGACTTCTTCCCCAAGAATGAGAGCGATCATTTTGTGGCCAGGGAGCGCGA
GGTGCTGGCCAGCGGAAAAGTCTTGGAAATCGCTGAGGAGCCCGTGCAGACGGCCAACAAGGGGATACGCCTGCTTCGCA
CCAAGAAGGTGGCGGTGCTCGGCGAGAACGGCCTAGCGACTCACCTCCTGGGAATTTCCGAGGATATTACCCAGCAAAAG
GAAATGGAAAAGGAAATCCTCAACCTCAATGCGATTTTGAAGGCTCGCGCTGAAGAACTGGAAGCCAGTCACAAAAGCCT
GGAAAGCTTTACGTCCGCAGCGACGCACGACCTTCGCTCGCCACTGAGCATCATCGGCGGCTATGCCGGCCTGCTGGAGA
AAAATTACGCCAGCCGGCTGGACGAAAAGGGTCAGCGCTATGTGTCGATCATCCGGGACAATATCAAAGGCATGGCCAAA
CTGATTGACGACCTGCTGGCCTTCTCCAAGCTGGGCCAGCGCGAGATCAGCAAAGCCAGTGTGAACATGCATGGACTGGC
CCAACAGGTCATCGAAGAACTCCTGCAACGCCATCCGGAGGGCAGCAAACCACGCGTCGTCCTGGAGTCGCTGCCGCCGG
CGCAGGCAGACGCTTCGCTGCTGCGCCAGGTCTGGGTGAACCTGCTGTCCAACGCCGTGAAGTACAGCAGTCGCACACCC
AACCCCCTGATCGAAATCAGTGGCCGCATAGACGGCGCGGAGGCCGTTTATTCGGTGCGTGACAACGGCGCCGGCTTCAG
CATGGACCACTACGACAAACTCTTCGAAATATTTCAGCGACTGCACACCGACGAGGAGTTTGAAGGGAACGGGGTGGGCT
TGCCCATCGTCCAGCGCGTGGTGACCCGGCATGGCGGCCGCGTGTGGGCCGAGGGCAAGGTGGGTCAGGGTGCGGTGTTT
CATTTTGCGCTGCCCGTATAG

Upstream 100 bases:

>100_bases
GCTACTACCGTGCGTGACTCCCAAAAGTCCGCAGTGGGTCTCATTGCGAGCAGCTCACGTCCCATGCACGGCCCGCTAGC
TCATCCTGCGGAAGGGCCCC

Downstream 100 bases:

>100_bases
CGTCAGCAGCGCCCGGTCTCAAGACTTGAACGGCCTTGCAGCCATCAGCCCGGGCTGTTTGCACCGGCAGCCCACGTTGA
AGCCTTAGCCCATGTCCAGC

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 565

Protein sequence:

>566_residues
MPSAEPSPVASPAPPAHILIAEDSGVQAYMLRRLLEEEGYATSVAKNGRLALELAARIRPSLLVSDVNMPEMSGYELCRQ
IKANPDLCHIPVILVTNLSDPDDVLLGLKSGADSFVIKPYDRTHMLARVQHALSNQHLRSTAEEGPGVEISFHGEKHQIT
ASRAQILNLLMSTYETTAQRNRELHESREELAKRTTELLAANRFLDSIIENIPNMIFIKDAAELKFVRLNRAGENLLGYS
RDQLLGKSDHDFFPKNESDHFVAREREVLASGKVLEIAEEPVQTANKGIRLLRTKKVAVLGENGLATHLLGISEDITQQK
EMEKEILNLNAILKARAEELEASHKSLESFTSAATHDLRSPLSIIGGYAGLLEKNYASRLDEKGQRYVSIIRDNIKGMAK
LIDDLLAFSKLGQREISKASVNMHGLAQQVIEELLQRHPEGSKPRVVLESLPPAQADASLLRQVWVNLLSNAVKYSSRTP
NPLIEISGRIDGAEAVYSVRDNGAGFSMDHYDKLFEIFQRLHTDEEFEGNGVGLPIVQRVVTRHGGRVWAEGKVGQGAVF
HFALPV

Sequences:

>Translated_566_residues
MPSAEPSPVASPAPPAHILIAEDSGVQAYMLRRLLEEEGYATSVAKNGRLALELAARIRPSLLVSDVNMPEMSGYELCRQ
IKANPDLCHIPVILVTNLSDPDDVLLGLKSGADSFVIKPYDRTHMLARVQHALSNQHLRSTAEEGPGVEISFHGEKHQIT
ASRAQILNLLMSTYETTAQRNRELHESREELAKRTTELLAANRFLDSIIENIPNMIFIKDAAELKFVRLNRAGENLLGYS
RDQLLGKSDHDFFPKNESDHFVAREREVLASGKVLEIAEEPVQTANKGIRLLRTKKVAVLGENGLATHLLGISEDITQQK
EMEKEILNLNAILKARAEELEASHKSLESFTSAATHDLRSPLSIIGGYAGLLEKNYASRLDEKGQRYVSIIRDNIKGMAK
LIDDLLAFSKLGQREISKASVNMHGLAQQVIEELLQRHPEGSKPRVVLESLPPAQADASLLRQVWVNLLSNAVKYSSRTP
NPLIEISGRIDGAEAVYSVRDNGAGFSMDHYDKLFEIFQRLHTDEEFEGNGVGLPIVQRVVTRHGGRVWAEGKVGQGAVF
HFALPV
>Mature_565_residues
PSAEPSPVASPAPPAHILIAEDSGVQAYMLRRLLEEEGYATSVAKNGRLALELAARIRPSLLVSDVNMPEMSGYELCRQI
KANPDLCHIPVILVTNLSDPDDVLLGLKSGADSFVIKPYDRTHMLARVQHALSNQHLRSTAEEGPGVEISFHGEKHQITA
SRAQILNLLMSTYETTAQRNRELHESREELAKRTTELLAANRFLDSIIENIPNMIFIKDAAELKFVRLNRAGENLLGYSR
DQLLGKSDHDFFPKNESDHFVAREREVLASGKVLEIAEEPVQTANKGIRLLRTKKVAVLGENGLATHLLGISEDITQQKE
MEKEILNLNAILKARAEELEASHKSLESFTSAATHDLRSPLSIIGGYAGLLEKNYASRLDEKGQRYVSIIRDNIKGMAKL
IDDLLAFSKLGQREISKASVNMHGLAQQVIEELLQRHPEGSKPRVVLESLPPAQADASLLRQVWVNLLSNAVKYSSRTPN
PLIEISGRIDGAEAVYSVRDNGAGFSMDHYDKLFEIFQRLHTDEEFEGNGVGLPIVQRVVTRHGGRVWAEGKVGQGAVFH
FALPV

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=389, Percent_Identity=27.2493573264781, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI48994928, Length=400, Percent_Identity=24.25, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786912, Length=222, Percent_Identity=30.1801801801802, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI145693157, Length=261, Percent_Identity=27.5862068965517, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790860, Length=195, Percent_Identity=29.7435897435897, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1790436, Length=229, Percent_Identity=26.2008733624454, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788550, Length=122, Percent_Identity=34.4262295081967, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87081816, Length=243, Percent_Identity=29.2181069958848, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788713, Length=268, Percent_Identity=23.5074626865672, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=138, Percent_Identity=35.5072463768116, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788394, Length=196, Percent_Identity=28.0612244897959, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082012, Length=162, Percent_Identity=29.6296296296296, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790299, Length=137, Percent_Identity=31.3868613138686, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787229, Length=119, Percent_Identity=33.6134453781513, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786600, Length=262, Percent_Identity=25.1908396946565, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786784, Length=239, Percent_Identity=24.6861924686192, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790863, Length=147, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789809, Length=132, Percent_Identity=31.0606060606061, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 62670; Mature: 62539

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSAEPSPVASPAPPAHILIAEDSGVQAYMLRRLLEEEGYATSVAKNGRLALELAARIRP
CCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEHHHCCCCEEEHHHHHCCC
SLLVSDVNMPEMSGYELCRQIKANPDLCHIPVILVTNLSDPDDVLLGLKSGADSFVIKPY
HHEEECCCCCCCCHHHHHHHHCCCCCEEEEEEEEEECCCCHHHHHEECCCCCCCEEECCC
DRTHMLARVQHALSNQHLRSTAEEGPGVEISFHGEKHQITASRAQILNLLMSTYETTAQR
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
NRELHESREELAKRTTELLAANRFLDSIIENIPNMIFIKDAAELKFVRLNRAGENLLGYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCHHHCCC
RDQLLGKSDHDFFPKNESDHFVAREREVLASGKVLEIAEEPVQTANKGIRLLRTKKVAVL
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHEECEEEEE
GENGLATHLLGISEDITQQKEMEKEILNLNAILKARAEELEASHKSLESFTSAATHDLRS
CCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLSIIGGYAGLLEKNYASRLDEKGQRYVSIIRDNIKGMAKLIDDLLAFSKLGQREISKAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
VNMHGLAQQVIEELLQRHPEGSKPRVVLESLPPAQADASLLRQVWVNLLSNAVKYSSRTP
CCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
NPLIEISGRIDGAEAVYSVRDNGAGFSMDHYDKLFEIFQRLHTDEEFEGNGVGLPIVQRV
CCEEEECCCCCCHHHHEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
VTRHGGRVWAEGKVGQGAVFHFALPV
HHHCCCEEEECCCCCCCEEEEEECCC
>Mature Secondary Structure 
PSAEPSPVASPAPPAHILIAEDSGVQAYMLRRLLEEEGYATSVAKNGRLALELAARIRP
CCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEHHHCCCCEEEHHHHHCCC
SLLVSDVNMPEMSGYELCRQIKANPDLCHIPVILVTNLSDPDDVLLGLKSGADSFVIKPY
HHEEECCCCCCCCHHHHHHHHCCCCCEEEEEEEEEECCCCHHHHHEECCCCCCCEEECCC
DRTHMLARVQHALSNQHLRSTAEEGPGVEISFHGEKHQITASRAQILNLLMSTYETTAQR
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
NRELHESREELAKRTTELLAANRFLDSIIENIPNMIFIKDAAELKFVRLNRAGENLLGYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCHHHCCC
RDQLLGKSDHDFFPKNESDHFVAREREVLASGKVLEIAEEPVQTANKGIRLLRTKKVAVL
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHEECEEEEE
GENGLATHLLGISEDITQQKEMEKEILNLNAILKARAEELEASHKSLESFTSAATHDLRS
CCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLSIIGGYAGLLEKNYASRLDEKGQRYVSIIRDNIKGMAKLIDDLLAFSKLGQREISKAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
VNMHGLAQQVIEELLQRHPEGSKPRVVLESLPPAQADASLLRQVWVNLLSNAVKYSSRTP
CCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
NPLIEISGRIDGAEAVYSVRDNGAGFSMDHYDKLFEIFQRLHTDEEFEGNGVGLPIVQRV
CCEEEECCCCCCHHHHEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
VTRHGGRVWAEGKVGQGAVFHFALPV
HHHCCCEEEECCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]