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The map label for this gene is rcsC [H]

Identifier: 91787693

GI number: 91787693

Start: 1875578

End: 1876123

Strand: Reverse

Name: rcsC [H]

Synonym: Bpro_1812

Alternate gene names: 91787693

Gene position: 1876123-1875578 (Counterclockwise)

Preceding gene: 91787694

Following gene: 91787692

Centisome position: 36.08

GC content: 62.09

Gene sequence:

>546_bases
ATGACCCTTGATCTGTCGCTGCCCATAGCGGATCCCGCGCAGCTTCCAGAAGGAAATCCAGGTGCCCCGGACTCATTTTT
TGCGAGCCTGGAGACACGCAGGGCAGCGCCTGACGTGGCGCAAGCCGAGGCAGAGGGCACGCTGATCCTGCTGGCCGATG
ACCACCCCACCAACCGCTCGCTGTTGATGCGCCAGGTAAACCTGCTCGGCTATGCGGCAGAGAGCGCCAGAAACGGCGTC
GAAGCCCTGAACCTGTGGAAGTCGGGCCGATTTTCGCTGCTCCTGACAGACTGCAACATGCCCGAAATGGACGGCTATGA
ACTGGCCAAGGCTATACGCGCGCTCGAAGCAGCCACAGCCGCCCGTCACTACCCCGTCATTGCCTGCACAGCCAATGCCA
TGGGCGGTGAAGCAGAAATTTGCCTCGCCGCGGGTATGGACGACTACCTTGTCAAGCCGGTGGAGTTAAAAAAACTGCGG
CCAGCCTGGCGCGCTGGCTACCCATCCCCGCGGCCCCCGTCACACCGCCCGCCTATTTTCCTGTAG

Upstream 100 bases:

>100_bases
CTTTGGCGATACAGGCCTCGGTCTGGTTATCTGCCGCCGGCTGGCGGCCTTGATAGGCGGCTCCATCACCATGGAGAGCA
CGCCTGGCAAAGGAACCACC

Downstream 100 bases:

>100_bases
CACGGCGGGCGAGGACACCGATTGACCATGTGGCGCTGGCCAGAGTGTCTGCGGGCGATGCGGCCGTCGAGCGCGACATT
TTCATCGAGTTTCAACGGGC

Product: response regulator receiver domain-containing protein

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MTLDLSLPIADPAQLPEGNPGAPDSFFASLETRRAAPDVAQAEAEGTLILLADDHPTNRSLLMRQVNLLGYAAESARNGV
EALNLWKSGRFSLLLTDCNMPEMDGYELAKAIRALEAATAARHYPVIACTANAMGGEAEICLAAGMDDYLVKPVELKKLR
PAWRAGYPSPRPPSHRPPIFL

Sequences:

>Translated_181_residues
MTLDLSLPIADPAQLPEGNPGAPDSFFASLETRRAAPDVAQAEAEGTLILLADDHPTNRSLLMRQVNLLGYAAESARNGV
EALNLWKSGRFSLLLTDCNMPEMDGYELAKAIRALEAATAARHYPVIACTANAMGGEAEICLAAGMDDYLVKPVELKKLR
PAWRAGYPSPRPPSHRPPIFL
>Mature_180_residues
TLDLSLPIADPAQLPEGNPGAPDSFFASLETRRAAPDVAQAEAEGTLILLADDHPTNRSLLMRQVNLLGYAAESARNGVE
ALNLWKSGRFSLLLTDCNMPEMDGYELAKAIRALEAATAARHYPVIACTANAMGGEAEICLAAGMDDYLVKPVELKKLRP
AWRAGYPSPRPPSHRPPIFL

Specific function: Member of the two-component regulatory system RcsC/RcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with RcsF, RcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=125, Percent_Identity=42.4, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1788713, Length=152, Percent_Identity=40.7894736842105, Blast_Score=87, Evalue=5e-19,
Organism=Escherichia coli, GI1789149, Length=112, Percent_Identity=36.6071428571429, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788191, Length=106, Percent_Identity=38.6792452830189, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1788550, Length=111, Percent_Identity=36.9369369369369, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 19523; Mature: 19391

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDLSLPIADPAQLPEGNPGAPDSFFASLETRRAAPDVAQAEAEGTLILLADDHPTNRS
CEEEECCCCCCHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHCCCCEEEEEECCCCCCHH
LLMRQVNLLGYAAESARNGVEALNLWKSGRFSLLLTDCNMPEMDGYELAKAIRALEAATA
HHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
ARHYPVIACTANAMGGEAEICLAAGMDDYLVKPVELKKLRPAWRAGYPSPRPPSHRPPIF
HHCCCEEEEECCCCCCCCEEEEECCCHHHHCCCHHHHHCCHHHHCCCCCCCCCCCCCCCC
L
C
>Mature Secondary Structure 
TLDLSLPIADPAQLPEGNPGAPDSFFASLETRRAAPDVAQAEAEGTLILLADDHPTNRS
EEEECCCCCCHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHCCCCEEEEEECCCCCCHH
LLMRQVNLLGYAAESARNGVEALNLWKSGRFSLLLTDCNMPEMDGYELAKAIRALEAATA
HHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
ARHYPVIACTANAMGGEAEICLAAGMDDYLVKPVELKKLRPAWRAGYPSPRPPSHRPPIF
HHCCCEEEEECCCCCCCCEEEEECCCHHHHCCCHHHHHCCHHHHCCCCCCCCCCCCCCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2404948; 8366025; 9097040; 9278503; 11758943; 11309126; 13129944 [H]