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The map label for this gene is aroA [H]

Identifier: 91787672

GI number: 91787672

Start: 1850655

End: 1852661

Strand: Reverse

Name: aroA [H]

Synonym: Bpro_1790

Alternate gene names: 91787672

Gene position: 1852661-1850655 (Counterclockwise)

Preceding gene: 91787673

Following gene: 91787671

Centisome position: 35.63

GC content: 63.83

Gene sequence:

>2007_bases
ATGTTCGATATTGAGTACCTGGATATTCCGCCACTGGCCCGGGCGGGAGGAACAGTCCGACTGCCCGGCTCCAAAAGCAT
TTCCAACCGCGTCCTGCTGCTGGCCGCACTGAGCCGGGGACAAACCACGGTGCACGACCTGCTGGCCTCTGACGACACCG
CCGTGATGCTGGCGGCCCTGAAACAGCTGGGCTGCAGCGTGGCACAGCACGGAACCACCGCCGTCATCGACGGGCTCGGT
GGCCAGGTCGGACAGGCCAAAGCCACGCTTTTCATGGGCAATGCCGGCACCGCGATGCGCCCCCTGACGGCCGCCCTGGC
GCTGCTGGGTGGCGAGTTTGAACTCTCGGGCGTTGCCCGCATGCATGAAAGACCGATCGGCGATCTGGTCGATGCGCTCC
GGCAACTGGGCTGCTCCATCGAGTACCTCGGCAACGAGGGCTATCCACCGCTGCGCCTGCGTCCCGCCCAGCTGAAGATC
GAAGAGCCTATCCGGGTACGGGGCGATGTTTCCAGCCAGTTCCTGACAGCGCTGCTGATGGCTTTGCCGCTGGTAGCCGG
GCAGGACATCCACATTGAAGTGGTGGGCGAACTGATTTCCCGTCCCTATATCGAGATCACCCTCAACCTGCTCAAGCGCT
TTGGCATTCACGTCCAGCGGCCGCTGGGTGCTGACAACTGGCAGCGGTTTACCATCCCGGCCGGGAGCCAGTACCAGTCG
CCCGGCGACATCCATGTCGAGGGCGACGCCTCGTCCGCCAGCTATTTCATAGCACTCGGTGCAATTTCCGAGCCGGCTGC
AGGGCAAAACCACATAGAAATTCTGGGTGTAGGCGCCGACTCGATCCAGGGGGACATCCGCTTTATTGAGGCTGCCCGGA
TGATGGGCGCGCAGATTGAAAGCACGCCCAACTCGCTGCGGATTTCCCGCGGCAAACCAGGCCAGGGATGGCCGCTCAAG
GCGATCGACCTGGACTGCAACCACATCCCCGATGCCGCCATGACGCTGGCCGTGATGGCGCTGTATGCAGACGGCACGAC
CACGCTGCGCAATATCGCCAGCTGGCGCGTCAAGGAAACCGACCGCATCGCCGCCATGGCCTGCGAACTGCAAAAGCTCG
GCGCCACCGTGGAGGAAGGCGCGGACTATCTCAAGATCACGCCGCCCCTGGCGTGGAAAAGTGCCGCCATTCACACCTAC
GACGATCACCGCATCGCCATGTGCTTTTCGCTGGCGGCCTTCAATCCGGCCCGGCAGCCGATACGGATTCTCGACCCCAA
GTGCGTCGCCAAGACCTTCCCCGATTATTTCGAAGCCCTGTTTGCCGTGTCCGAAGCCGAAACCGCGCAGATTCCCGTCA
TCTGCATCGACGGCCCGACGGCCTCGGGCAAGGGTACGCTGGCTGCACTGGCCGCCCACCGGCTTGGCTACCACTACCTG
GACTCCGGCGCCCTGTATCGTTTGAGCGCCTTTGCCGCCACGCGCGCCGGCGTGGCGCTGGAGAATGGTGCCGACGTGGC
GCGCATCGCCCGGACGCTGCCGGTCCGCTTTCGGGGCGACCGGATATTCCTGGGCACCGAAGACGTGTCCGAAGCCATCC
GCACCGAGGCTGCGGGTATGGCCGCCTCCAAAGTGTCGGCGCACCCCGAGGTGCGTAGCGCCCTGCTGGAGCTCCAGCAC
AGCTTTCGGCGCCTGCCGGGGCTGGTGGCGGATGGCCGGGACATGGGAACCGTCATATTCCCCGATGCCCCCCTCAAGGT
CTACCTGACGGCAAGCGCCCTGCACCGGGCTGAACGCAGGCATAAGCAATTGATTTCAAAGGGAATTTCGGCTACAATCG
CCGGGATTCAGCAAGATTTGGAGGCGCGCGACGCCCGCGACATGTCCAGGCCGGTCGCCCCTTTGAAACCTGCTGATGAC
GCCCGCCCGCTGGACAACTCCTATCTGTCGATTGAAAACTCGGTAGCTCAGGTGATTGACTGGTGGGAAGGCAGTCGGCC
CTTCTGA

Upstream 100 bases:

>100_bases
GGCAGTGGTGATGTGCTGGAGGTGCTGATCGAGCAAGCCAGCGAAACGCGCGCCAACTGGCGCATGTCCTCGCATAAATC
CCATAAATAAGTCCCGGTTC

Downstream 100 bases:

>100_bases
CCCCCGACGCGCTCACCTCATCACGGCGCACTGGTCAGCAGGTTCATTAACGCAACCCGCGGCCTTATTAGACGTCTGGC
CGCAAAAACCGCCGCAAGCA

Product: bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidine monophosphate kinase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 668; Mature: 668

Protein sequence:

>668_residues
MFDIEYLDIPPLARAGGTVRLPGSKSISNRVLLLAALSRGQTTVHDLLASDDTAVMLAALKQLGCSVAQHGTTAVIDGLG
GQVGQAKATLFMGNAGTAMRPLTAALALLGGEFELSGVARMHERPIGDLVDALRQLGCSIEYLGNEGYPPLRLRPAQLKI
EEPIRVRGDVSSQFLTALLMALPLVAGQDIHIEVVGELISRPYIEITLNLLKRFGIHVQRPLGADNWQRFTIPAGSQYQS
PGDIHVEGDASSASYFIALGAISEPAAGQNHIEILGVGADSIQGDIRFIEAARMMGAQIESTPNSLRISRGKPGQGWPLK
AIDLDCNHIPDAAMTLAVMALYADGTTTLRNIASWRVKETDRIAAMACELQKLGATVEEGADYLKITPPLAWKSAAIHTY
DDHRIAMCFSLAAFNPARQPIRILDPKCVAKTFPDYFEALFAVSEAETAQIPVICIDGPTASGKGTLAALAAHRLGYHYL
DSGALYRLSAFAATRAGVALENGADVARIARTLPVRFRGDRIFLGTEDVSEAIRTEAAGMAASKVSAHPEVRSALLELQH
SFRRLPGLVADGRDMGTVIFPDAPLKVYLTASALHRAERRHKQLISKGISATIAGIQQDLEARDARDMSRPVAPLKPADD
ARPLDNSYLSIENSVAQVIDWWEGSRPF

Sequences:

>Translated_668_residues
MFDIEYLDIPPLARAGGTVRLPGSKSISNRVLLLAALSRGQTTVHDLLASDDTAVMLAALKQLGCSVAQHGTTAVIDGLG
GQVGQAKATLFMGNAGTAMRPLTAALALLGGEFELSGVARMHERPIGDLVDALRQLGCSIEYLGNEGYPPLRLRPAQLKI
EEPIRVRGDVSSQFLTALLMALPLVAGQDIHIEVVGELISRPYIEITLNLLKRFGIHVQRPLGADNWQRFTIPAGSQYQS
PGDIHVEGDASSASYFIALGAISEPAAGQNHIEILGVGADSIQGDIRFIEAARMMGAQIESTPNSLRISRGKPGQGWPLK
AIDLDCNHIPDAAMTLAVMALYADGTTTLRNIASWRVKETDRIAAMACELQKLGATVEEGADYLKITPPLAWKSAAIHTY
DDHRIAMCFSLAAFNPARQPIRILDPKCVAKTFPDYFEALFAVSEAETAQIPVICIDGPTASGKGTLAALAAHRLGYHYL
DSGALYRLSAFAATRAGVALENGADVARIARTLPVRFRGDRIFLGTEDVSEAIRTEAAGMAASKVSAHPEVRSALLELQH
SFRRLPGLVADGRDMGTVIFPDAPLKVYLTASALHRAERRHKQLISKGISATIAGIQQDLEARDARDMSRPVAPLKPADD
ARPLDNSYLSIENSVAQVIDWWEGSRPF
>Mature_668_residues
MFDIEYLDIPPLARAGGTVRLPGSKSISNRVLLLAALSRGQTTVHDLLASDDTAVMLAALKQLGCSVAQHGTTAVIDGLG
GQVGQAKATLFMGNAGTAMRPLTAALALLGGEFELSGVARMHERPIGDLVDALRQLGCSIEYLGNEGYPPLRLRPAQLKI
EEPIRVRGDVSSQFLTALLMALPLVAGQDIHIEVVGELISRPYIEITLNLLKRFGIHVQRPLGADNWQRFTIPAGSQYQS
PGDIHVEGDASSASYFIALGAISEPAAGQNHIEILGVGADSIQGDIRFIEAARMMGAQIESTPNSLRISRGKPGQGWPLK
AIDLDCNHIPDAAMTLAVMALYADGTTTLRNIASWRVKETDRIAAMACELQKLGATVEEGADYLKITPPLAWKSAAIHTY
DDHRIAMCFSLAAFNPARQPIRILDPKCVAKTFPDYFEALFAVSEAETAQIPVICIDGPTASGKGTLAALAAHRLGYHYL
DSGALYRLSAFAATRAGVALENGADVARIARTLPVRFRGDRIFLGTEDVSEAIRTEAAGMAASKVSAHPEVRSALLELQH
SFRRLPGLVADGRDMGTVIFPDAPLKVYLTASALHRAERRHKQLISKGISATIAGIQQDLEARDARDMSRPVAPLKPADD
ARPLDNSYLSIENSVAQVIDWWEGSRPF

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=446, Percent_Identity=53.1390134529148, Blast_Score=415, Evalue=1e-117,
Organism=Escherichia coli, GI1787139, Length=218, Percent_Identity=48.6238532110092, Blast_Score=186, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6320332, Length=556, Percent_Identity=34.1726618705036, Blast_Score=255, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 71787; Mature: 71787

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDIEYLDIPPLARAGGTVRLPGSKSISNRVLLLAALSRGQTTVHDLLASDDTAVMLAAL
CCCCEEECCCCHHHCCCEEECCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCHHHHHHHH
KQLGCSVAQHGTTAVIDGLGGQVGQAKATLFMGNAGTAMRPLTAALALLGGEFELSGVAR
HHHCCHHHHCCCEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEHHHHH
MHERPIGDLVDALRQLGCSIEYLGNEGYPPLRLRPAQLKIEEPIRVRGDVSSQFLTALLM
HHCCCHHHHHHHHHHHCCEEEEECCCCCCCCEEECCCEEECCCCEECCCCHHHHHHHHHH
ALPLVAGQDIHIEVVGELISRPYIEITLNLLKRFGIHVQRPLGADNWQRFTIPAGSQYQS
HHHHHCCCCEEHHHHHHHHHCCHHHHHHHHHHHCCCEEECCCCCCCCEEEECCCCCCCCC
PGDIHVEGDASSASYFIALGAISEPAAGQNHIEILGVGADSIQGDIRFIEAARMMGAQIE
CCCEEEECCCCCCEEEEEEECCCCCCCCCCCEEEEEECCHHCCCHHHHHHHHHHHCCHHC
STPNSLRISRGKPGQGWPLKAIDLDCNHIPDAAMTLAVMALYADGTTTLRNIASWRVKET
CCCCCEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCH
DRIAAMACELQKLGATVEEGADYLKITPPLAWKSAAIHTYDDHRIAMCFSLAAFNPARQP
HHHHHHHHHHHHHCCCHHCCCCEEEECCCCCCCCCEEEECCCCEEEEHHHHHHCCCCCCC
IRILDPKCVAKTFPDYFEALFAVSEAETAQIPVICIDGPTASGKGTLAALAAHRLGYHYL
CEECCCHHHHHHCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCEEE
DSGALYRLSAFAATRAGVALENGADVARIARTLPVRFRGDRIFLGTEDVSEAIRTEAAGM
CCCCHHHHHHHHHHHCCEEECCCCHHHHHHHHCCEEECCCEEEECCHHHHHHHHHHHHCC
AASKVSAHPEVRSALLELQHSFRRLPGLVADGRDMGTVIFPDAPLKVYLTASALHRAERR
HHHHHCCCHHHHHHHHHHHHHHHHCCCCEECCCCCCEEEECCCCEEEEEEHHHHHHHHHH
HKQLISKGISATIAGIQQDLEARDARDMSRPVAPLKPADDARPLDNSYLSIENSVAQVID
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHH
WWEGSRPF
HCCCCCCC
>Mature Secondary Structure
MFDIEYLDIPPLARAGGTVRLPGSKSISNRVLLLAALSRGQTTVHDLLASDDTAVMLAAL
CCCCEEECCCCHHHCCCEEECCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCHHHHHHHH
KQLGCSVAQHGTTAVIDGLGGQVGQAKATLFMGNAGTAMRPLTAALALLGGEFELSGVAR
HHHCCHHHHCCCEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEHHHHH
MHERPIGDLVDALRQLGCSIEYLGNEGYPPLRLRPAQLKIEEPIRVRGDVSSQFLTALLM
HHCCCHHHHHHHHHHHCCEEEEECCCCCCCCEEECCCEEECCCCEECCCCHHHHHHHHHH
ALPLVAGQDIHIEVVGELISRPYIEITLNLLKRFGIHVQRPLGADNWQRFTIPAGSQYQS
HHHHHCCCCEEHHHHHHHHHCCHHHHHHHHHHHCCCEEECCCCCCCCEEEECCCCCCCCC
PGDIHVEGDASSASYFIALGAISEPAAGQNHIEILGVGADSIQGDIRFIEAARMMGAQIE
CCCEEEECCCCCCEEEEEEECCCCCCCCCCCEEEEEECCHHCCCHHHHHHHHHHHCCHHC
STPNSLRISRGKPGQGWPLKAIDLDCNHIPDAAMTLAVMALYADGTTTLRNIASWRVKET
CCCCCEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCH
DRIAAMACELQKLGATVEEGADYLKITPPLAWKSAAIHTYDDHRIAMCFSLAAFNPARQP
HHHHHHHHHHHHHCCCHHCCCCEEEECCCCCCCCCEEEECCCCEEEEHHHHHHCCCCCCC
IRILDPKCVAKTFPDYFEALFAVSEAETAQIPVICIDGPTASGKGTLAALAAHRLGYHYL
CEECCCHHHHHHCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCEEE
DSGALYRLSAFAATRAGVALENGADVARIARTLPVRFRGDRIFLGTEDVSEAIRTEAAGM
CCCCHHHHHHHHHHHCCEEECCCCHHHHHHHHCCEEECCCEEEECCHHHHHHHHHHHHCC
AASKVSAHPEVRSALLELQHSFRRLPGLVADGRDMGTVIFPDAPLKVYLTASALHRAERR
HHHHHCCCHHHHHHHHHHHHHHHHCCCCEECCCCCCEEEECCCCEEEEEEHHHHHHHHHH
HKQLISKGISATIAGIQQDLEARDARDMSRPVAPLKPADDARPLDNSYLSIENSVAQVID
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHH
WWEGSRPF
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA