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The map label for this gene is waaA [H]

Identifier: 91787523

GI number: 91787523

Start: 1696607

End: 1697932

Strand: Direct

Name: waaA [H]

Synonym: Bpro_1641

Alternate gene names: 91787523

Gene position: 1696607-1697932 (Clockwise)

Preceding gene: 91787522

Following gene: 91787524

Centisome position: 32.63

GC content: 67.42

Gene sequence:

>1326_bases
ATGAGCCAGCTGTTGCTGCGGCTTTATTCGCTGGCCATGGTGCTGGCGCAACCCATGCTGCGTCGCAAGCTGGCGCGGCG
CGGCCAGCGCGAGCCCGGCTATCTGACGGCGGTTGAAGAGCGCTTTGGCCACTACACCCAGCCGGCCGAGACTTCTTCCG
AACTGGTGTGGGTGCATGCTGTGTCACTCGGGGAAACACGTACCGCGGCCATGCTGCTCAAGGCCTTGCGCGCGCAGTAC
CCGGGCCTGCGAATTTTGCTCACGCACGGCACGGCCACCGGCCGCGCCGAGGGTGCGGCGCTGCTGCAGCCCGGCGATGT
GCAGGTGTGGCAACCCTGGGACAGCCTGGCTGCCGTGGCGCGTTTTTTCAATCACTTCAGGCCACGGCTGGGCCTGCTGA
TGGAAACCGAGATATGGCCCAACACCGTGGCCGCTGCCCGCGCGCGCGCCATGCCGCTGGTGCTCGTCAATGGACGCCTG
TCAGACAAATCATTGCAGCAGGCGCTGCGCATCGCGCTGCTGTCTTTGCCGGCCTACGGCGCGCTAGCCGCGGTGTACGC
GCAGACCGAAGACGACGCGCGGCGCTTTCGTCAGCTTGGCGCGCCGGTGACCGGCGTGTTTGGCAACCTCAAGTTTGATG
CCACGCCCAGCGCCGGCCAGCAGACGCAAGGCCGGGCATGGCGGCAGGCGCTGGCACAGCCGGTGCTGATGTTCGCCAGT
TCGCGCGAAGGCGAAGAAGCCGATTTCCTCAAGCAGATAAAGGCTGCGACCCAGGAAAAAGTTGAGCTGTCAGCCATGAG
TTCGGCAGCCAATGAATCCGCCAGGGCTTTCCATGCACTGATCGTTCCCCGCCACCCGCAGCGCTTCGACGAAGTGGCGG
CCCTGGTGGAGCAGCACGGCCTGCGCGTGTCGCGCCGCTCGCAGTGGACGGGCGGCCCCGCCGACAGCGACGAAGCCCGG
CAGGCCGATGTCTGGCTTGGCGACTCCCTGGGCGAGATGGCGCTGTACTACGGCCTCAGCGATGTGGCCCTGCTCGGTGG
CAGCTTTGCGCCCCTGGGCGGCCAGAATTTAATCGAGGCCGCAGCCTGCGGCTGCCCGGTGGTGATGGGGCCACACACCT
TCAACTTTGCCGAGGCCGCCGAGCTGGCCGAGGCCGAAGGCGCAGCCCTGCGCGTAGCCGACATGCCCGAGGCCGTCCAG
GCCGCGTTGGTTTTGGTGAGCGACCTGCCGGCGCTGGCAGCGGCCGTGGATTCCGGCCTGGCGTTCGCGGCCCGCAATCG
GGGTGCGGCTGCAAAGACGCTGGATGCGTTGCGCGCCTACTTGTGA

Upstream 100 bases:

>100_bases
TGTTTGCGCAACCCACCCCCAGCGTTGATGTCGTGTGGCAGGCCTGGCTGGCTTGCCGGCAGGCCCCTGCGGCGGCGCAT
ACGACCATTGTGGCCGCCCC

Downstream 100 bases:

>100_bases
GTTGCGTCCCGCTGGGGCCGGTTGTGGGGGCGGGGCAGCGCGAGCCCAGTTGAACATTCCAACATGCAGGCTTTCACGGA
TTTTTTATTGCCCCTTGAGT

Product: three-deoxy-D-manno-octulosonic-acid transferase-like protein

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MSQLLLRLYSLAMVLAQPMLRRKLARRGQREPGYLTAVEERFGHYTQPAETSSELVWVHAVSLGETRTAAMLLKALRAQY
PGLRILLTHGTATGRAEGAALLQPGDVQVWQPWDSLAAVARFFNHFRPRLGLLMETEIWPNTVAAARARAMPLVLVNGRL
SDKSLQQALRIALLSLPAYGALAAVYAQTEDDARRFRQLGAPVTGVFGNLKFDATPSAGQQTQGRAWRQALAQPVLMFAS
SREGEEADFLKQIKAATQEKVELSAMSSAANESARAFHALIVPRHPQRFDEVAALVEQHGLRVSRRSQWTGGPADSDEAR
QADVWLGDSLGEMALYYGLSDVALLGGSFAPLGGQNLIEAAACGCPVVMGPHTFNFAEAAELAEAEGAALRVADMPEAVQ
AALVLVSDLPALAAAVDSGLAFAARNRGAAAKTLDALRAYL

Sequences:

>Translated_441_residues
MSQLLLRLYSLAMVLAQPMLRRKLARRGQREPGYLTAVEERFGHYTQPAETSSELVWVHAVSLGETRTAAMLLKALRAQY
PGLRILLTHGTATGRAEGAALLQPGDVQVWQPWDSLAAVARFFNHFRPRLGLLMETEIWPNTVAAARARAMPLVLVNGRL
SDKSLQQALRIALLSLPAYGALAAVYAQTEDDARRFRQLGAPVTGVFGNLKFDATPSAGQQTQGRAWRQALAQPVLMFAS
SREGEEADFLKQIKAATQEKVELSAMSSAANESARAFHALIVPRHPQRFDEVAALVEQHGLRVSRRSQWTGGPADSDEAR
QADVWLGDSLGEMALYYGLSDVALLGGSFAPLGGQNLIEAAACGCPVVMGPHTFNFAEAAELAEAEGAALRVADMPEAVQ
AALVLVSDLPALAAAVDSGLAFAARNRGAAAKTLDALRAYL
>Mature_440_residues
SQLLLRLYSLAMVLAQPMLRRKLARRGQREPGYLTAVEERFGHYTQPAETSSELVWVHAVSLGETRTAAMLLKALRAQYP
GLRILLTHGTATGRAEGAALLQPGDVQVWQPWDSLAAVARFFNHFRPRLGLLMETEIWPNTVAAARARAMPLVLVNGRLS
DKSLQQALRIALLSLPAYGALAAVYAQTEDDARRFRQLGAPVTGVFGNLKFDATPSAGQQTQGRAWRQALAQPVLMFASS
REGEEADFLKQIKAATQEKVELSAMSSAANESARAFHALIVPRHPQRFDEVAALVEQHGLRVSRRSQWTGGPADSDEARQ
ADVWLGDSLGEMALYYGLSDVALLGGSFAPLGGQNLIEAAACGCPVVMGPHTFNFAEAAELAEAEGAALRVADMPEAVQA
ALVLVSDLPALAAAVDSGLAFAARNRGAAAKTLDALRAYL

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA). Transfers two molecules of KDO to lipid IVA [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=440, Percent_Identity=34.5454545454545, Blast_Score=217, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR007507 [H]

Pfam domain/function: PF00534 Glycos_transf_1; PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 47415; Mature: 47284

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLLLRLYSLAMVLAQPMLRRKLARRGQREPGYLTAVEERFGHYTQPAETSSELVWVHA
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEE
VSLGETRTAAMLLKALRAQYPGLRILLTHGTATGRAEGAALLQPGDVQVWQPWDSLAAVA
ECCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEECCCCCEEECCHHHHHHHH
RFFNHFRPRLGLLMETEIWPNTVAAARARAMPLVLVNGRLSDKSLQQALRIALLSLPAYG
HHHHHHCHHHCCEEECCCCCCHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHCCCHH
ALAAVYAQTEDDARRFRQLGAPVTGVFGNLKFDATPSAGQQTQGRAWRQALAQPVLMFAS
HHHHHHHCCHHHHHHHHHHCCCHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHC
SREGEEADFLKQIKAATQEKVELSAMSSAANESARAFHALIVPRHPQRFDEVAALVEQHG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHC
LRVSRRSQWTGGPADSDEARQADVWLGDSLGEMALYYGLSDVALLGGSFAPLGGQNLIEA
CCCCCCCCCCCCCCCCCCHHHCCEEECCCHHHHHHHHCCHHHHHHCCCCCCCCCHHHHHH
AACGCPVVMGPHTFNFAEAAELAEAEGAALRVADMPEAVQAALVLVSDLPALAAAVDSGL
HHCCCCEEECCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCH
AFAARNRGAAAKTLDALRAYL
HHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SQLLLRLYSLAMVLAQPMLRRKLARRGQREPGYLTAVEERFGHYTQPAETSSELVWVHA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEE
VSLGETRTAAMLLKALRAQYPGLRILLTHGTATGRAEGAALLQPGDVQVWQPWDSLAAVA
ECCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEECCCCCEEECCHHHHHHHH
RFFNHFRPRLGLLMETEIWPNTVAAARARAMPLVLVNGRLSDKSLQQALRIALLSLPAYG
HHHHHHCHHHCCEEECCCCCCHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHCCCHH
ALAAVYAQTEDDARRFRQLGAPVTGVFGNLKFDATPSAGQQTQGRAWRQALAQPVLMFAS
HHHHHHHCCHHHHHHHHHHCCCHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHC
SREGEEADFLKQIKAATQEKVELSAMSSAANESARAFHALIVPRHPQRFDEVAALVEQHG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHC
LRVSRRSQWTGGPADSDEARQADVWLGDSLGEMALYYGLSDVALLGGSFAPLGGQNLIEA
CCCCCCCCCCCCCCCCCCHHHCCEEECCCHHHHHHHHCCHHHHHHCCCCCCCCCHHHHHH
AACGCPVVMGPHTFNFAEAAELAEAEGAALRVADMPEAVQAALVLVSDLPALAAAVDSGL
HHCCCCEEECCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCH
AFAARNRGAAAKTLDALRAYL
HHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]