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The map label for this gene is hrcA

Identifier: 91787199

GI number: 91787199

Start: 1347287

End: 1348303

Strand: Direct

Name: hrcA

Synonym: Bpro_1303

Alternate gene names: 91787199

Gene position: 1347287-1348303 (Clockwise)

Preceding gene: 91787195

Following gene: 91787200

Centisome position: 25.91

GC content: 60.28

Gene sequence:

>1017_bases
ATGCTTGATGATCGTGCCCGGTTGTTGCTCAAGGCGCTGGTGGAGCGCTACATTGCTGATGGTCAGCCGGTCGGGTCGCG
CACGCTGTCCAGGGCCTCCGGTCTTGAACTGTCTCCGGCCACCATACGCAATGTCATGAGCGATCTGGAGGAGCTGGGCC
TGATTGTCAGCCCGCATACCTCTGCCGGCCGCATCCCAACCGCCCGCGGCTACCGCCTCTTCGTCGACACCATGCTGACC
ACGCAGCGCGACCAGCTTTCGGCTGGGCACATCACGGCGCCCAGGCTGGCACCCGATCAACCACAGAAGGTGATCAGCAA
CGCCGCCCACATGCTGTCCAGCCTGTCGCAGTTCGTCGGCGTGGTCATGGCGCCGCGCCGCACGTCGGTGTTCCGGCATA
TCGAGTTTTTGCGCCTGTCGGAAAAACGGTTTCTTGTGATCATCGTCTCACCGGACGGCGACGTGCAAAACCGCGTCATC
TTTACCGAGGCAGACTACACGCAGTCCCAGTTGATCGAAGCCTCCAACTTCCTCAATTCGCACTATGCGGGCATGGCTAT
TGAAGAAGTGCGGGAGCGCCTGCAAAATGAGGTGGAAGCGCTCAGGGGCGAAATTGCCACGTTGATGCAGGCTGCCGTCC
AGGTGAGTTCCGAGGCCATCGAATCGCGCGACGAGGTGGTGGTGTCAGGCGAACGCAATCTGCTGGCCGTCAGCGATTTT
TCCAGCGACATGGGCAACCTGCGCAAGCTCTTTGATCTTTTTGAGCAGAAGGCTCAACTGATGCGCCTGCTCGATGTGTC
AAGCCGCGCCGAGGGCGTGCGCATTTACATTGGCGGCGAAAGCCAGGTCATTCCCTACCAGGAACTCTCGGTGGTGACGG
CACCTTACGAGGTGGACGGCCAGGTCGTGGGAACGCTGGGCGTCATCGGCCCCATGCGCATGCCGTACGAAAAAATGATC
CAGATTGTCGATATCACCTCCAAACTGGTCAGCACGGCCCTGAGCCACAGCAAGTAG

Upstream 100 bases:

>100_bases
CTGGGCGTGGTACTTGCCGATCAGTGCGACATGGCGAAATTGCGATTTCATCGGCAAATTACATCACAACATGGTGATAG
AAGCTTCGTAGAATGTCAGT

Downstream 100 bases:

>100_bases
GCCCTTACAATCTGCCTGTCGATGGGGGGCGTTAGCTCAGTTGGTTAGAGCAGAGGACTCATAATCCTTTGGTCGTTGGT
TCAAGTCCAACACGCCCTAC

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MLDDRARLLLKALVERYIADGQPVGSRTLSRASGLELSPATIRNVMSDLEELGLIVSPHTSAGRIPTARGYRLFVDTMLT
TQRDQLSAGHITAPRLAPDQPQKVISNAAHMLSSLSQFVGVVMAPRRTSVFRHIEFLRLSEKRFLVIIVSPDGDVQNRVI
FTEADYTQSQLIEASNFLNSHYAGMAIEEVRERLQNEVEALRGEIATLMQAAVQVSSEAIESRDEVVVSGERNLLAVSDF
SSDMGNLRKLFDLFEQKAQLMRLLDVSSRAEGVRIYIGGESQVIPYQELSVVTAPYEVDGQVVGTLGVIGPMRMPYEKMI
QIVDITSKLVSTALSHSK

Sequences:

>Translated_338_residues
MLDDRARLLLKALVERYIADGQPVGSRTLSRASGLELSPATIRNVMSDLEELGLIVSPHTSAGRIPTARGYRLFVDTMLT
TQRDQLSAGHITAPRLAPDQPQKVISNAAHMLSSLSQFVGVVMAPRRTSVFRHIEFLRLSEKRFLVIIVSPDGDVQNRVI
FTEADYTQSQLIEASNFLNSHYAGMAIEEVRERLQNEVEALRGEIATLMQAAVQVSSEAIESRDEVVVSGERNLLAVSDF
SSDMGNLRKLFDLFEQKAQLMRLLDVSSRAEGVRIYIGGESQVIPYQELSVVTAPYEVDGQVVGTLGVIGPMRMPYEKMI
QIVDITSKLVSTALSHSK
>Mature_338_residues
MLDDRARLLLKALVERYIADGQPVGSRTLSRASGLELSPATIRNVMSDLEELGLIVSPHTSAGRIPTARGYRLFVDTMLT
TQRDQLSAGHITAPRLAPDQPQKVISNAAHMLSSLSQFVGVVMAPRRTSVFRHIEFLRLSEKRFLVIIVSPDGDVQNRVI
FTEADYTQSQLIEASNFLNSHYAGMAIEEVRERLQNEVEALRGEIATLMQAAVQVSSEAIESRDEVVVSGERNLLAVSDF
SSDMGNLRKLFDLFEQKAQLMRLLDVSSRAEGVRIYIGGESQVIPYQELSVVTAPYEVDGQVVGTLGVIGPMRMPYEKMI
QIVDITSKLVSTALSHSK

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_POLSJ (Q12DY9)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_548151.1
- ProteinModelPortal:   Q12DY9
- SMR:   Q12DY9
- STRING:   Q12DY9
- GeneID:   4012197
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_1303
- NMPDR:   fig|296591.1.peg.1960
- eggNOG:   COG1420
- HOGENOM:   HBG729878
- OMA:   LEQPHTS
- ProtClustDB:   PRK00082
- BioCyc:   PSP296591:BPRO_1303-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00081
- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF03444 DUF293; PF01628 HrcA

EC number: NA

Molecular weight: Translated: 37358; Mature: 37358

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDDRARLLLKALVERYIADGQPVGSRTLSRASGLELSPATIRNVMSDLEELGLIVSPHT
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEECCCC
SAGRIPTARGYRLFVDTMLTTQRDQLSAGHITAPRLAPDQPQKVISNAAHMLSSLSQFVG
CCCCCCCCCCCEEEHHHHHHCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VVMAPRRTSVFRHIEFLRLSEKRFLVIIVSPDGDVQNRVIFTEADYTQSQLIEASNFLNS
HHCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHH
HYAGMAIEEVRERLQNEVEALRGEIATLMQAAVQVSSEAIESRDEVVVSGERNLLAVSDF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECC
SSDMGNLRKLFDLFEQKAQLMRLLDVSSRAEGVRIYIGGESQVIPYQELSVVTAPYEVDG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHEEEECCEECCC
QVVGTLGVIGPMRMPYEKMIQIVDITSKLVSTALSHSK
EEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDDRARLLLKALVERYIADGQPVGSRTLSRASGLELSPATIRNVMSDLEELGLIVSPHT
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEECCCC
SAGRIPTARGYRLFVDTMLTTQRDQLSAGHITAPRLAPDQPQKVISNAAHMLSSLSQFVG
CCCCCCCCCCCEEEHHHHHHCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VVMAPRRTSVFRHIEFLRLSEKRFLVIIVSPDGDVQNRVIFTEADYTQSQLIEASNFLNS
HHCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHH
HYAGMAIEEVRERLQNEVEALRGEIATLMQAAVQVSSEAIESRDEVVVSGERNLLAVSDF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECC
SSDMGNLRKLFDLFEQKAQLMRLLDVSSRAEGVRIYIGGESQVIPYQELSVVTAPYEVDG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHEEEECCEECCC
QVVGTLGVIGPMRMPYEKMIQIVDITSKLVSTALSHSK
EEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA