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The map label for this gene is nadA [H]

Identifier: 91786805

GI number: 91786805

Start: 920918

End: 922051

Strand: Direct

Name: nadA [H]

Synonym: Bpro_0903

Alternate gene names: 91786805

Gene position: 920918-922051 (Clockwise)

Preceding gene: 91786804

Following gene: 91786806

Centisome position: 17.71

GC content: 66.58

Gene sequence:

>1134_bases
ATGGGCGCCGTGACTGACGTGATTGATGTTGAATACGACTCGCCGCACCCGGCGGCGGTTCCGGGCGCCTCGGCGTGCGA
CACCAGGCACGCCTGGGCGCGTGTACCGGTCGAGCCCGGCCCCAAGCAGCGTGCCGCGCTCAAGGACAAGATCCGCCGGC
TGCTGAAGGAGCGCAACGCGGTGATGGTGTCGCACTACTACGTGCACCCCGACCTGCAGGACCTGGCCGAGGAAACCGGC
GGTATCGTCAGCGACTCGCTGGAGATGGCGCGCTTTGGCCAGAACCATGCGGCGCAGACGCTGGTGGTCTCGGGCGTGCG
CTTCATGGGCGAGACGGCCAAGATTGTTTCGCCCGAAAAGCGCGTGCTGATGCCCGACCTCGACGCGACCTGCTCGCTGG
ACCTGGGGTGTCCGGTCGATGAGTTCAGCGCTTTTTGCGACGCGCACCCGGACCGCACCGTGGTAGTCTATGCCAACACC
AGCGCGGCCGTGAAGGCGCGCGCCGACTGGGTGGTCACATCCAGCTGCGCGCTCGACATTGTGCAGGCACTGAAAGACAA
GGGGCACAAGATCTTGTGGGCGCCCGACAAGCATCTGGGCGGCTACATCCAGCGCCAGACTGGCGCCGATATGGTGTTCT
GGAACGGCACCTGCATCGTGCACGACGAGTTCAAGGCCTTCGAGCTCGAAGCGCTCAAGAAGGAGCACCCGAAAGCCAGG
GTGCTGGTGCATCCCGAGTCACCGGCCGATGTGGTGGCGCTGGCCGACGCGGTGGGTTCCACCTCGGCCATCCTGAAAGC
CGCGCGCGAACTGGACGCCCCGGAGTTCATTGTCGCCACCGACAGCGGCATGATGCACAAGCTGCGCACACTCAACCCCG
GCAAGATCTTCATCGAGGCGCCGACGGCTGGCAACAGCGCGACCTGCAAGAGCTGCGCGCACTGCCCCTGGATGGCCATG
AACAGCCTGGCGGGCCTGGCCCATGTGCTGGAGACCGGCCGCAATGAAATTCACGTTGATCCGGCGCTGGGCCTGCGTGC
CCGCCTGCCGATTGACCGCATGCTGGCGTTCACCGCTGCGCTGAAGGCCGGCCAGCCGGCGGGCGCGCTGGTGCCGAACA
TCGGCGCGGCCTGA

Upstream 100 bases:

>100_bases
GGCCGAAACTGGCGTGGACCGGATTTCCATTGGCGGCCTGACCAAGGACGTCAAGGCCATCGATTTCTCGATGCGTTTTC
ACGAGCTGTAAGGAACTGCG

Downstream 100 bases:

>100_bases
TGGGAGCCTTGTCGGCACTCATCGACTTCTCCAACCCGGACCATCCCGACGGGCCACGTTTGCGCCAGGCCTTTGGCGTG
GCGCGCCAGGTGCTGGTGGC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MGAVTDVIDVEYDSPHPAAVPGASACDTRHAWARVPVEPGPKQRAALKDKIRRLLKERNAVMVSHYYVHPDLQDLAEETG
GIVSDSLEMARFGQNHAAQTLVVSGVRFMGETAKIVSPEKRVLMPDLDATCSLDLGCPVDEFSAFCDAHPDRTVVVYANT
SAAVKARADWVVTSSCALDIVQALKDKGHKILWAPDKHLGGYIQRQTGADMVFWNGTCIVHDEFKAFELEALKKEHPKAR
VLVHPESPADVVALADAVGSTSAILKAARELDAPEFIVATDSGMMHKLRTLNPGKIFIEAPTAGNSATCKSCAHCPWMAM
NSLAGLAHVLETGRNEIHVDPALGLRARLPIDRMLAFTAALKAGQPAGALVPNIGAA

Sequences:

>Translated_377_residues
MGAVTDVIDVEYDSPHPAAVPGASACDTRHAWARVPVEPGPKQRAALKDKIRRLLKERNAVMVSHYYVHPDLQDLAEETG
GIVSDSLEMARFGQNHAAQTLVVSGVRFMGETAKIVSPEKRVLMPDLDATCSLDLGCPVDEFSAFCDAHPDRTVVVYANT
SAAVKARADWVVTSSCALDIVQALKDKGHKILWAPDKHLGGYIQRQTGADMVFWNGTCIVHDEFKAFELEALKKEHPKAR
VLVHPESPADVVALADAVGSTSAILKAARELDAPEFIVATDSGMMHKLRTLNPGKIFIEAPTAGNSATCKSCAHCPWMAM
NSLAGLAHVLETGRNEIHVDPALGLRARLPIDRMLAFTAALKAGQPAGALVPNIGAA
>Mature_376_residues
GAVTDVIDVEYDSPHPAAVPGASACDTRHAWARVPVEPGPKQRAALKDKIRRLLKERNAVMVSHYYVHPDLQDLAEETGG
IVSDSLEMARFGQNHAAQTLVVSGVRFMGETAKIVSPEKRVLMPDLDATCSLDLGCPVDEFSAFCDAHPDRTVVVYANTS
AAVKARADWVVTSSCALDIVQALKDKGHKILWAPDKHLGGYIQRQTGADMVFWNGTCIVHDEFKAFELEALKKEHPKARV
LVHPESPADVVALADAVGSTSAILKAARELDAPEFIVATDSGMMHKLRTLNPGKIFIEAPTAGNSATCKSCAHCPWMAMN
SLAGLAHVLETGRNEIHVDPALGLRARLPIDRMLAFTAALKAGQPAGALVPNIGAA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=332, Percent_Identity=62.9518072289157, Blast_Score=431, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 40441; Mature: 40310

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAVTDVIDVEYDSPHPAAVPGASACDTRHAWARVPVEPGPKQRAALKDKIRRLLKERNA
CCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCE
VMVSHYYVHPDLQDLAEETGGIVSDSLEMARFGQNHAAQTLVVSGVRFMGETAKIVSPEK
EEEEEEEECCCHHHHHHHHCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHCCCCC
RVLMPDLDATCSLDLGCPVDEFSAFCDAHPDRTVVVYANTSAAVKARADWVVTSSCALDI
EEECCCCCCCEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHH
VQALKDKGHKILWAPDKHLGGYIQRQTGADMVFWNGTCIVHDEFKAFELEALKKEHPKAR
HHHHHHCCCEEEECCCHHHCCEEECCCCCCEEEECCEEEEECCCCHHHHHHHHHCCCCEE
VLVHPESPADVVALADAVGSTSAILKAARELDAPEFIVATDSGMMHKLRTLNPGKIFIEA
EEECCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCCCEEEEEC
PTAGNSATCKSCAHCPWMAMNSLAGLAHVLETGRNEIHVDPALGLRARLPIDRMLAFTAA
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCHHHHHHHHHH
LKAGQPAGALVPNIGAA
HHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GAVTDVIDVEYDSPHPAAVPGASACDTRHAWARVPVEPGPKQRAALKDKIRRLLKERNA
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCE
VMVSHYYVHPDLQDLAEETGGIVSDSLEMARFGQNHAAQTLVVSGVRFMGETAKIVSPEK
EEEEEEEECCCHHHHHHHHCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHCCCCC
RVLMPDLDATCSLDLGCPVDEFSAFCDAHPDRTVVVYANTSAAVKARADWVVTSSCALDI
EEECCCCCCCEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHH
VQALKDKGHKILWAPDKHLGGYIQRQTGADMVFWNGTCIVHDEFKAFELEALKKEHPKAR
HHHHHHCCCEEEECCCHHHCCEEECCCCCCEEEECCEEEEECCCCHHHHHHHHHCCCCEE
VLVHPESPADVVALADAVGSTSAILKAARELDAPEFIVATDSGMMHKLRTLNPGKIFIEA
EEECCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCCCEEEEEC
PTAGNSATCKSCAHCPWMAMNSLAGLAHVLETGRNEIHVDPALGLRARLPIDRMLAFTAA
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCHHHHHHHHHH
LKAGQPAGALVPNIGAA
HHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA